Sample preparation for measurement of plasma mycophenolic acid concentrations using chromatographically functionalized magnetic micro-particles

European Journal of Mass Spectrometry

Volumn 18, Issue 5, 2012, Pages 413-417

  König, Katrin ^a   Vogeser, Michael ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Chromatography; Ferromagnetic micro particles; LC MS MS; Quantification; Sample preparation

Indexed keywords

AUTOMATION; CHROMATOGRAPHY; EXTRACTION; LIQUID CHROMATOGRAPHY; MAGNETISM; MASS SPECTROMETRY; PHASE SEPARATION;

LC-MS/MS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; MAGNETIC MICRO PARTICLES; MICRO PARTICLES; MYCOPHENOLIC ACIDS; QUANTIFICATION; SAMPLE PREPARATION; SOLID-PHASE EXTRACTION;

MAGNETOPLASMA;

IMMUNOSUPPRESSIVE AGENT; MYCOPHENOLIC ACID;

ARTICLE; AUTOMATION; BLOOD; CALIBRATION; CLINICAL CHEMISTRY; HUMAN; INSTRUMENTATION; LIQUID CHROMATOGRAPHY; MAGNETISM; MASS SPECTROMETRY; METHODOLOGY; REPRODUCIBILITY; SOLID PHASE EXTRACTION;

AUTOMATION; CALIBRATION; CHEMISTRY, CLINICAL; CHROMATOGRAPHY, LIQUID; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MAGNETICS; MASS SPECTROMETRY; MYCOPHENOLIC ACID; REPRODUCIBILITY OF RESULTS; SOLID PHASE EXTRACTION;

EID: 84870901712     PISSN: None     EISSN: 17516838     Source Type: Journal    
DOI: 10.1255/ejms.1197     Document Type: Article

References (16)

1. M. Vogeser, A. Geiger, R. Herrmann and U. Kobold, "Sample preparation for liquid chromatography-tandem mass spectrometry using functionalized ferromagnetic micro-particles", Clin. Biochem. 41, 1417 (2008). doi: 10.1016/j.clinbiochem.2008.08.001
2. I.I. Sukhanova, M.A. Dikunets, E.D. Viryus and G.M. Rodchenkov, "Magnetic separation as a new method for the extraction of small molecules from biological fluids of humans", J. Anal. Chem. 66, 9:807-814 (2011). doi: 10.1134/S1061934811090164
3. G.M. Fiedler, A.B. Leichtle, J. Kase, S. Baumann, U. Ceglarek, K. Felix, T. Conrad, H. Witzigmann, A. Weimann, C. Schutte, J. Hauss, M. Buchler and J. Thiery, "Serum peptidome profiling revealed platelet factor 4 as a potential discriminating peptide associated with pancreatic cancer", Clin. Cancer Res. 15, 3812 (2009). doi: 10.1158/1078-0432.CCR-08-2701
4. G.M. Fiedler, S. Baumann, A. Leichtle, A. Oltmann, J. Kase, J. Thiery and U. Ceglarek, "Standardized peptidome profiling of human urine by magnetic bead separation and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry", Clin. Chem. 53, 421 (2007).doi: 10.1373/clinchem.2006. 077834
5. J. Verheyen, R. Kaiser, M. Bozic, M. Timmen-Wego, B.K. Maier and H.H. Kessler, "Extraction of viral nucleic acids: comparison of five automated nucleic acid extraction platforms", J. Clin. Virol. 54, 255 (2012). doi: 10.1016/j.jcv.2012.03.008
6. P.L. Kole, G. Venkatesh, J. Kotecha and R. Sheshala, "Recent advances in sample preparation techniques for effective bioanalytical methods", Biomed. Chromatogr. 25, 199 (2011). doi: 10.1002/bmc.156
7. M. Vogeser and U. Spohrer, "Pitfall in the high-throughput quantification of whole blood cyclosporin A using liquid chromatography-tandem mass spectrometry", Clin. Chem. Lab. Med. 43, 400 (2005). doi: 10.1515/CCLM.2005.072
8. M. Vogeser and C. Seger, "A decade of HPLC-MS/MS in the routine clinical laboratory - goals for further developments", Clin. Biochem. 41, 649 (2008). doi: 10.1016/j.clinbiochem.2008.02.017
9. J.M. van den Ouweland and I.P. Kema, "The role of liquid chromatography-tandem mass spectrometry in the clinical laboratory", J. Chromatogr. B 883/884,1 (2012). doi: 10.1016/j.jchromb.2011.11.044
10. C.G. Patel, A.E. Mendonza, F. Akhlaghi, O. Majid, A.K. Trull, T. Lee and D.W. Holt, "Determination of total mycophenolic acid and its glucuronide metabolite using liquid chromatography with ultraviolet detection and unbound mycophenolic acid using tandem mass spectrometry", J. Chromatogr. B 813, 1-2:287-294 (2004). doi: 10.1016/j.jchromb.2004.10.004
11. T.M. Annesley and L.T. Clayton, "Quantification of mycophenolic acid and glucuronide metabolite in human serum by HPLC-tandem mass spectrometry", Clin. Chem. 51, 872 (2005). doi: 10.1373/clinchem.2004. 047357
12. A. Buchwald, K. Winkler and T. Epting, "Validation of an LC-MS/MS method to determine five immunosuppressants with deuterated internal standards including MPA", BMC Clin. Pharmacol. 12, (2012), doi: 10.1186/1472-6904-12- 2
13. I.S. Westley, B.C. Sallustio and R.G. Morris, "Validation of a high-performance liquid chromatography method for the measurement of mycophenolic acid and its glucuronide metabolites in plasma", Clin. Biochem. 38, 824 (2005). doi: 10.1016/j.clinbiochem.2005.05.008
14. M. Vogeser, R. Zachoval, U. Spohrer and K. Jacob, "Potential lack of specificity using electrospray tandem-mass spectrometry for the analysis of mycophenolic acid in serum", Ther. Drug Monit. 23, 722 (2012).
15. T.M. Annesley, "Ion suppression in mass spectrometry", Clin. Chem. 49, 1041 (2003).
16. H.T. Kuo, J.Z. Yeh, C.M. Jiang and M.C. Wu, "Magnetic particle-linked anti hCG beta antibody for immunoassay of human chorionic gonadotropin (hCG), potential application to early pregnancy diagnosis", J. Immunol. Methods 381, 32 (2012). doi: 10.1016/j.jim.2012.04.006