MALDI-TOF mass spectrometry - A rapid method for the identification of dermatophyte species

Medical Mycology

Volumn 51, Issue 1, 2013, Pages 17-24

  Nenoff, Pietro ^a   Erhard, Marcel ^b   Simon, Jan C ^c   Muylowa, Grace K ^d   Herrmann, Jürgen ^a   Rataj, Waldemar ^a,c   Gräser, Yvonne ^e  

^a Haut und Laborarzt Allergologie Andrologie Labor für Medizinische Mikrobiologie Partnerschaft Prof Dr Med Pietro Nenoff and Dr Med Constanze Krüger   (Germany)

^b AnagnosTec Gesellschaft für Analytische Biochemie und Diagnostik mbH   (Germany)

^c UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^d MBARARA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Uganda)

^e CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Dermatophyte; Identification; MALDI TOF mass spectrometry

Indexed keywords

INTERNAL TRANSCRIBED SPACER; RIBOSOME DNA;

ARTHRODERMA; ARTICLE; DERMATOPHYTE; DNA SEQUENCE; EPIDERMOPHYTON FLOCCOSUM; FUNGAL STRAIN; FUNGUS IDENTIFICATION; FUNGUS ISOLATION; HUMAN; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MICROSPORUM CANIS; NONHUMAN; POLYMERASE CHAIN REACTION; TRICHOPHYTON MENTAGROPHYTES; TRICHOPHYTON RUBRUM;

EID: 84870896003     PISSN: 13693786     EISSN: 14602709     Source Type: Journal    
DOI: 10.3109/13693786.2012.685186     Document Type: Article

References (26)

1. M ü gge C, Haustein UF, Nenoff P. Causative agents of onychomycosis - a retrospective study. J Dtsch Dermatol Ges 2006; 4: 218 - 228.
2. Gr ä ser Y, Scott J, Summerbell RC. The new species concept in dermatophytes - a polyphasic approach. Mycopathologia 2008; 166: 239 - 256.
3. Heidemann S, Monod M, Gr ä ser Y. Signature polymorphisms in the internal transcribed spacer region relevant for the differentiation of zoophilic and anthropophilic strains of Trichophyton interdigitale and other species of T. mentagrophytes sensu lato. Br J Dermatol 2010; 162: 282- 295.
4. Nenoff P, M ü gge C, Haustein UF. Differentiation of clinically important dermatophytes. Part I: Trichophyton. Derm Prakt Dermatol 2002; 8: 16 - 31 [in German].
5. Sch ö nborn C. Special fungal diagnostics. In: Wildf ü hr G, Wildf ü hr W (eds). Medical Microbiology, Immunology and Epidemiology (Vol. IV/2), 2nd ed. Leipzig, Germany:Georg Thieme Publisher, 1982: 691 - 746 [in German].
6. Kallow W, Erhard M, Shah H, Raptakis E, Welker M. MALDI-TOF MS for microbial identifi cation: Years of experimental development to an established protocol. In: Phah H, Gharbia S, (eds). Mass Spectrometry for Microbial Proteomics, 1st edn. New York: John Wiley & Sons, 2010: 255 - 276.
7. Rataj W, Erhard M, Gr ä ser Y, e t al. Prevalence of dermatophytes at Mbarara, Uganda, East Africa - comparison of classical mycological species differentiation with molecular biological methods (analysis of the internal transcribed spacer region of the ribosomale DNA) and MALDI-TOF mass spectroscopy. Mycoses 2007; 50: 335 (abstract).
8. Summerbell RC. T richophyton, Microsporum, Epidermophyton, and agents of superfi cial mycoses. In: Murray PR, Baron EJ, Jorgensen JH, Pfaller MA, Yolken RH (eds). Manual of Clinical Microbiology, 8th edn. Washington DC: ASM Press, 2003: 1798 - 1819.
9. Summerbell RC, Kane J. The genera T richophyton and E pidermophyton. In: Kane J, Summerbell RC, Sigler L, Krajden S, Land G (eds). Laboratory Handbook of Dermatophytes. Belmont: Ptar Publishing Company, 1997: 131 - 191.
10. de Hoog GS, Gerrits van den Ende AH. Molecular diagnostics of clinical strains of fi lamentous Basidiomycetes. Mycoses 1998; 41: 183- 189.
11. Stackebrandt E, P ä uker O, Erhard M. Grouping myxococci (C orallococcus) strains by Matrix-Assisted Laser Desorption Ionization Timeof-Flight (MALDI TOF) mass spectrometry: Comparison with gene sequence phylogenies. Curr Microbiol 2005; 50: 71 - 77.
12. De Hoog GS, Guarro J, Gen é J, Figueras MJ. A tlas of Clinical Fungi, 3rd edn. Utrecht, The Netherlands: Centraalbureau voor Schimmelculture and Universitat Rovira i Virgili, 2009.
13. Arabatzis M, Bruijnesteijn van Coppenraet LE, et al. Diagnosis of common dermatophyte infections by a novel multiplex real-time polymerase chain reaction detection/identifi cation scheme. Br J Dermatol 2007; 157: 681 - 689.
14. Bergmans AM, Schouls LM, van der Ent M, et al. Validation of PCRreverse line blot, a method for rapid detection and identifi cation of nine dermatophyte species in nail, skin and hair samples. Clin Microbiol Infect 2008; 14: 778 - 788.
15. Bergmans AM, van der Ent M, Klaassen A, e t al. Evaluation of a singletube real-time PCR for detection and identifi cation of 11 dermatophyte species in clinical material. Clin Microbiol Infect 2010; 16: 704- 710.
16. Gr ä ser Y, El Fari M, Presber W, Sterry W, Tietz HJ. Identifi cation of common dermatophytes (Trichophyton, Microsporum, Epidermophyton) using PCR fi ngerprinting. Br J Dermatol 1998; 138: 576 - 582.
17. Kanbe T, Suzuki Y, Kamiya A, et al. Species-identifi cation of dermatophytes Trichophyton, Microsporum and Epidermophyton by PCR and PCR-RFLP targeting of the DNA topoisomerase II genes. J Dermatol Science 2003; 33: 41 - 54.
18. Kardejeva V, Summerbell RC, Kantardjiev T, et al. Rapid diagnosis of onychomycosis with subtyping of Trichophyton rubrum strains. J Clin Microbiol 2006; 44: 1419 - 1427.
19. Donohue MJ, Smallwood AW, Pfaller S, Rodgers M, Shoemaker JA. The development of a matrix-assisted laser desorption/ionization mass spectrometry-based method for the protein fi ngerprinting and identifi cation of Aeromonas species using whole cells. J Microbiol Methods 2006; 65: 380 - 389.
20. Donohue MJ, Best JM, Smallwood JM, e t al. Differentiation of Aeromonas isolated from drinking water distribution systems using matrixassisted laser desorption/ionization-mass spectrometry. Anal Chem 2007; 79: 1939 - 1946.
21. Pignone M, Greth KM, Cooper J, Emerson D, Tang J. Identifi cation of mycobacteria by matrix-assisted laser desorption ionization-timeof-fl ight mass spectrometry. J Clin Microbiol 2006; 44: 1963 - 1970.
22. Ikryannikova LN, Afanas'ev MV, Akopian TA, e t al. Massspectrometry based minisequencing method for the rapid detection of drug resistance in Mycobacterium tuberculosis. J Microbiol Methods 2007; 70: 395 - 405.
23. Erhard M, Hipler UC. SARAMIS-MALDI-TOF MS analysis of Aspergillus species. Mycoses 2007; 50: 352 (abstract).
24. Erhard M, Hipler UC, Burmester A, Brakhage AA, W ö stemeyer J. Identifi cation of dermatophyte species causing onychomycosis and tinea pedis by MALDI-TOF mass spectrometry. Exp Dermatol 2008; 17: 356 - 361.
25. Gr ä ser Y, De Hoog S, Summerbell RC. Dermatophytes: Recognizing species of clonal fungi. Med Mycol 2006; 44: 199 - 209.
26. Nenoff P, Herrmann J, Gr ä ser Y. T richophyton mentagrophytes sive interdigitale ? A dermatophyte in the course of time. J Dtsch Dermatol Ges 2007; 5: 198 - 203.