A New Framework for Interpreting the Outcomes of Imperfectly Blinded Controlled Clinical Trials

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Arandjelović, Ognjen ^a  

^a DEAKIN UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BLIND PROCEDURE; CLINICAL PRACTICE; CONTROLLED CLINICAL TRIAL (TOPIC); DATA COLLECTION METHOD; METHODOLOGY; QUESTIONNAIRE; RESEARCH SUBJECT; STATISTICAL ANALYSIS; STATISTICAL MODEL; STUDY DESIGN;

CLINICAL TRIALS AS TOPIC; HUMANS; RESEARCH DESIGN; STATISTICS AS TOPIC;

EID: 84870839703     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048984     Document Type: Article

References (15)

1. Moerman DE, Jonas WB, (2002) Deconstructing the placebo effect and finding the meaning response. Ann Intern Med 136: 471-476.
2. Benedetti F, Mayberg HS, Wager TD, Stohler CS, Zubieta JK, (2005) Neurobiological mechanisms of the placebo effect. J Neurosci 25: 10390-10402.
3. Montgomery GH, Kirsch I, (1997) Classical conditioning and the placebo effect. Pain 72: 107-113.
4. Kolahi J, Bang H, Park J, (2009) Towards a proposal for assessment of blinding success in clinical trials: up-to-date review. Community Dent Oral Epidemiol 37: 477-484.
5. Colford JM, Rees JR, Wade TJ, Khalakdina A, Hilton JF, et al. (2002) Participant blinding and gastrointestinal illness in a randomized, controlled trial of an in-home drinking water intervention. Emerg Infect Dis 8: 29-36.
6. James KE, Bloch DA, Lee KK, Kraemer HC, Fuller RK, (1996) An index for assessing blindness in a multi-centre clinical trial: disulfiram for alcohol cessation-a va cooperative study. Stat Med 15: 1421-1434.
7. Beecher HK, (1955) The powerful placebo. JAMA 159: 1602-1606.
8. Mayberg HS, Silva JA, Brannan SK, Tekell JL, Mahurin RK, et al. (2002) The functional neuroanatomy of the placebo effect. Am J Psychiatry 159: 728-737.
9. Bang H, Ni L, Davis CE, (2004) Assessment of blinding in clinical trials. Contemp Clin Trials 25: 143-156.
10. Hemilä H, (2005) Assessment of blinding may be inappropriate after the trial. Contemp Clin Trials 26: 512-514.
11. Henneicke-von Zepelin HH, (2005) Letter to the editor. Contemp Clin Trials 26: 512.
12. Berger V (2005) Selection Bias and Covariate Imbalances in Randomized Clinical Trials. Hoboken, New Jersey: Wiley.
13. Costantino G, Furfaro F, Belvedere A, Alibrandi A, Fries W, (2011) Thiopurine treatment in in-ammatory bowel disease: Response predictors, safety, and withdrawal in follow-up. J Crohns Colitis.
14. Karakitsos D, Papanikolaou J, Karabinis A, Alalawi R, Wachtel M, et al. (2012) Acute effect of sildenafil on central hemodynamics in mechanically ventilated patients with WHO group III pulmonary hypertension and right ventricular failure necessitating administration of dobutamine. Int J Cardiol.
15. Bishop CM (2007) Pattern Recognition and Machine Learning. New York, USA: Springer-Verlag.