The effects of low-dose epinephrine infusion on spleen size, central and hepatic circulation and circulating platelets

Clinical Physiology and Functional Imaging

Volumn 33, Issue 1, 2013, Pages 30-37

  Bakovic, Darija ^b   Pivac, Nediljko ^b   Eterovic, Davor ^b   Breskovic, Toni ^a   Zubin, Petra ^a   Obad, Ante ^a   Dujic, Zeljko ^a  

^a UNIVERSITY OF SPLIT   (Croatia)

^b UNIVERSITY HOSPITAL SPLIT   (Croatia)

Author keywords

Large platelets; Mean platelet volume; Risk of thrombosis; Spleen volume; Sympathetic stimulation

Indexed keywords

ADRENALIN;

ADULT; ARTICLE; BLOOD SAMPLING; DRUG EFFECT; ECHOGRAPHY; HEART OUTPUT; HUMAN; LIVER BLOOD FLOW; LIVER CIRCULATION; LOW DRUG DOSE; LYMPHOID TISSUE; MALE; MEAN ARTERIAL PRESSURE; NORMAL HUMAN; PRIORITY JOURNAL; SAMPLING; SPLEEN BLOOD FLOW; SPLEEN SIZE; SYSTEMIC CIRCULATION; THROMBOCYTE COUNT; THROMBOCYTE VOLUME; VASCULAR RESISTANCE;

ADULT; BLOOD FLOW VELOCITY; BLOOD PLATELETS; BLOOD PRESSURE; CARDIAC OUTPUT; EPINEPHRINE; ERYTHROCYTE INDICES; HEART RATE; HEPATIC VEINS; HUMANS; INFUSIONS, INTRAVENOUS; LEUKOCYTE COUNT; LIVER CIRCULATION; MALE; ORGAN SIZE; PLATELET COUNT; SPLEEN; SYMPATHOMIMETICS; TIME FACTORS; VASCULAR RESISTANCE; YOUNG ADULT;

EID: 84870803990     PISSN: 14750961     EISSN: 1475097X     Source Type: Journal    
DOI: 10.1111/j.1475-097X.2012.01156.x     Document Type: Article

References (42)

1. Allsop P, Peters AM, Arnot RN, Stuttle AW, Deenmamode M, Gwilliam ME, Myers MJ, Hall GM. Intrasplenic blood cell kinetics in man before and after brief maximal exercise. Clin Sci (Lond) (1992); 83: 47-54.
2. Aster RH. Pooling of platelets in the spleen: role in the pathogenesis of "hypersplenic" thrombocytopenia. J Clin Invest (1966); 45: 645-657.
3. Bakovic D, Valic Z, Eterovic D, Vukovic I, Obad A, Marinovic-Terzic I, Dujic Z. Spleen volume and blood flow response to repeated breath-hold apneas. J Appl Physiol (2003); 95: 1460-1466.
4. Bakovic D, Eterovic D, Saratlija-Novakovic Z, Palada I, Valic Z, Bilopavlovic N, Dujic Z. Effect of human splenic contraction on variation in circulating blood cell counts. Clin Exp Pharmacol Physiol (2005); 32: 944-951.
5. Bakovic D, Eterovic D, Palada I, Valic Z, Dujic Z. Does breath-holding increase the risk of a thrombotic event? Platelets (2008); 19: 314-315.
6. Bakovic D, Pivac N, Eterovic D, Palada I, Valic Z, Paukovic-Sekulic B, Dujic Z. Changes in platelet size and spleen volume in response to selective and non-selective beta-adrenoceptor blockade in hypertensive patients. Clin Exp Pharmacol Physiol (2009); 36: 441-446.
7. Bessman JD. The relation of megakaryocyte ploidy to platelet volume. Am J Hematol (1984); 16: 161-170.
8. Braekkan SK, Mathiesen EB, Njolstad I, Wilsgaard T, Stormer J, Hansen JB. Mean platelet volume is a risk factor for venous thromboembolism: the Tromso Study, Tromso, Norway. J Thromb Haemost (2010); 8: 157-162.
9. Branehog I, Weinfeld A, Roos B. The exchangeable splenic platelet pool studied with epinephrine infusion in idiopathic thrombocytopenic purpura and in patients with splenomegaly. Br J Haematol (1973); 25: 239-248.
10. Breskovic T, Valic Z, Lipp A, Heusser K, Ivancev V, Tank J, Dzamonja G, Jordan J, Shoemaker JK, Eterovic D, Dujic Z. Peripheral chemoreflex regulation of sympathetic vasomotor tone in apnea divers. Clin Auton Res (2010); 20: 57-63.
11. Brown AS, Hong Y, de BA, Beacon H, Beeso J, Sherwood R, Edmonds M, Martin JF, Erusalimsky JD. Megakaryocyte ploidy and platelet changes in human diabetes and atherosclerosis. Arterioscler Thromb Vasc Biol (1997); 17: 802-807.
12. Burr ML, Holliday RM, Fehily AM, Whitehead PJ. Haematological prognostic indices after myocardial infarction: evidence from the diet and reinfarction trial (DART). Eur Heart J (1992); 13: 166-170.
13. Butterworth RJ, Bath PM. The relationship between mean platelet volume, stroke subtype and clinical outcome. Platelets (1998); 9: 359-364.
14. Cavalcanti JS, Andrade LP, Moreira IE, Rietra PH, Oliveira ML. A morphological and functional study of the cavo-hepatic junction in the human. Surg Radiol Anat (1995); 17: 311-314.
15. Chamberlain KG, Tong M, Penington DG. Properties of the exchangeable splenic platelets released into the circulation during exercise-induced thrombocytosis. Am J Hematol (1990); 34: 161-168.
16. Feigenbaum H. Hemodynamic information derived from echocardiography. In: Echocardiography (eds Ruth, W, Joyce, M, Alicia, J) (1994), pp. 181-184. Lea & Febiger, Philadelphia.
17. Gibson JB. The hepatic veins in man and their sphincter mechanisms. J Anat (1959); 93: 368-379.
18. Gill RW. Measurement of blood flow by ultrasound: accuracy and sources of error. Ultrasound Med Biol (1985); 11: 625-641.
19. Glud T, Schmidt EB, Kristensen SD, Arnfred T. Platelet number and volume during myocardial infarction in relation to infarct size. Acta Med Scand (1986); 220: 401-405.
20. Hendra TJ, Oswald GA, Yudkin JS. Increased mean platelet volume after acute myocardial infarction relates to diabetes and to cardiac failure. Diabetes Res Clin Pract (1988); 5: 63-69.
21. Heusser K, Dzamonja G, Breskovic T, Steinback CD, Diedrich A, Tank J, Jordan J, Dujic Z. Sympathetic and cardiovascular responses to glossopharyngeal insufflation in trained apnea divers. J Appl Physiol (2010); 109: 1728-1735.
22. Horn JR, Zierler B, Bauer LA, Reiss W, Strandness DE Jr. Estimation of hepatic blood flow in branches of hepatic vessels utilizing a noninvasive, duplex Doppler method. J Clin Pharmacol (1990); 30: 922-929.
23. Huczek Z, Kochman J, Filipiak KJ, Horszczaruk GJ, Grabowski M, Piatkowski R, Wilczynska J, Zielinski A, Meier B, Opolski G. Mean platelet volume on admission predicts impaired reperfusion and long-term mortality in acute myocardial infarction treated with primary percutaneous coronary intervention. J Am Coll Cardiol (2005); 46: 284-290.
24. Jellema WT, Wesseling KH, Groeneveld AB, Stoutenbeek CP, Thijs LG, van Lieshout JJ. Continuous cardiac output in septic shock by simulating a model of the aortic input impedance: a comparison with bolus injection thermodilution. Anesthesiology (1999); 90: 1317-1328.
25. Klein RL, Wilson SP, Dzielak DJ, Yang WH, Viveros OH. Opioid peptides and noradrenaline co-exist in large dense-cored vesicles from sympathetic nerve. Neuroscience (1982); 7: 2255-2261.
26. Koga T. Correlation between sectional area of the spleen by ultrasonic tomography and actual volume of the removed spleen. J Clin Ultrasound (1979); 7: 119-120.
27. Laub M, Hvid-Jacobsen K, Hovind P, Kanstrup IL, Christensen NJ, Nielsen SL. Spleen emptying and venous hematocrit in humans during exercise. J Appl Physiol (1993); 74: 1024-1026.
28. Lodin-Sundstrom A, Schagatay E. Spleen contraction during 20 min normobaric hypoxia and 2 min apnea in humans. Aviat Space Environ Med (2010); 81: 545-549.
29. Martin JF, Bath PM, Burr ML. Influence of platelet size on outcome after myocardial infarction. Lancet (1991); 338: 1409-1411.
30. Meierhenrich R, Gauss A, Vandenesch P, Georgieff M, Poch B, Schutz W. The effects of intraabdominally insufflated carbon dioxide on hepatic blood flow during laparoscopic surgery assessed by transesophageal echocardiography. Anesth Analg (2005); 100: 340-347.
31. Palada I, Eterovic D, Obad A, Bakovic D, Valic Z, Ivancev V, Lojpur M, Shoemaker JK, Dujic Z. Spleen and cardiovascular function during short apneas in divers. J Appl Physiol (2007); 103: 1958-1963.
32. Pizzulli L, Yang A, Martin JF, Luderitz B. Changes in platelet size and count in unstable angina compared to stable angina or non-cardiac chest pain. Eur Heart J (1998); 19: 80-84.
33. Rupp H. Sympathetic overactivity - pathophysiological link between hypertension, diabetes, coronary heart disease, stroke and kidney disease. "Translational medicine in hypertension" (2010).
34. Schagatay E, Haughey H, Reimers J. Speed of spleen volume changes evoked by serial apneas. Eur J Appl Physiol (2005); 93: 447-452.
35. Schutz W, Meierhenrich R, Trager K, Gauss A, Radermacher P, Georgieff M. Is it feasible to monitor total hepatic blood flow by use of transesophageal echography? An experimental study in pigs. Intensive Care Med (2001); 27: 580-585.
36. Sloand JA, Hooper M, Izzo JL Jr. Effects of circulating norepinephrine on platelet, leukocyte and red blood cell counts by alpha 1-adrenergic stimulation. Am J Cardiol (1989); 63: 1140-1142.
37. Stewart IB, Warburton DE, Hodges AN, Lyster DM, McKenzie DC. Cardiovascular and splenic responses to exercise in humans. J Appl Physiol (2003); 94: 1619-1626.
38. Thompson CB, Diaz DD, Quinn PG, Lapins M, Kurtz SR, Valeri CR. The role of anticoagulation in the measurement of platelet volumes. Am J Clin Pathol (1983); 80: 327-332.
39. Thornton SJ, Spielman DM, Pelc NJ, Block WF, Crocker DE, Costa DP, LeBoeuf BJ, Hochachka PW. Effects of forced diving on the spleen and hepatic sinus in northern elephant seal pups. Proc Natl Acad Sci USA (2001); 98: 9413-9418.
40. Yang A, Pizzulli L, Luderitz B. Mean platelet volume as marker of restenosis after percutaneous transluminal coronary angioplasty in patients with stable and unstable angina pectoris. Thromb Res (2006); 117: 371-377.
41. Yilmaz MB, Akin Y, Biyikoglu SF, Guray U, Kisacik HL, Korkmaz S. Left ventricular thrombosis is associated with increased mean platelet volume in patients with dilated cardiomyopathy and sinus rhythm. Acta Cardiol (2004a); 59: 41-45.
42. Yilmaz MB, Saricam E, Biyikoglu SF, Guray Y, Guray U, Sasmaz H, Korkmaz S. Mean platelet volume and exercise stress test. J Thromb Thrombolysis (2004b); 17: 115-120.