Cerebral blood flow identifies responders to transcranial magnetic stimulation in auditory verbal hallucinations

Translational Psychiatry

Volumn 2, Issue , 2012, Pages

  Homan, P ^a   Kindler, J ^a   Hauf, M ^a   Hubl, D ^a   Dierks, T ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

arterial spin labeling; auditory verbal hallucinations; cerebral blood flow; schizophrenia; superior temporal gyrus; transcranial magnetic stimulation

Indexed keywords

ADULT; ARTICLE; AUDITORY HALLUCINATION; BRAIN BLOOD FLOW; BRAIN PERFUSION; CLINICAL ARTICLE; FEMALE; HUMAN; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; SCHIZOAFFECTIVE PSYCHOSIS; SPIN LABELING; SUPERIOR TEMPORAL GYRUS; TRANSCRANIAL MAGNETIC STIMULATION; BRAIN; BRAIN CIRCULATION; ELECTRON SPIN RESONANCE; HALLUCINATION; METHODOLOGY; MIDDLE AGED; PROGNOSIS; SCHIZOPHRENIA; TEMPORAL LOBE; TREATMENT OUTCOME; VASCULARIZATION;

ADULT; BRAIN; CEREBROVASCULAR CIRCULATION; ELECTRON SPIN RESONANCE SPECTROSCOPY; FEMALE; HALLUCINATIONS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PROGNOSIS; SCHIZOPHRENIA; TEMPORAL LOBE; TRANSCRANIAL MAGNETIC STIMULATION; TREATMENT OUTCOME;

EID: 84870793382     PISSN: None     EISSN: 21583188     Source Type: Journal    
DOI: 10.1038/tp.2012.114     Document Type: Article

References (53)

1. Sartorius N, Jablensky A, Korten A, Ernberg G, Anker M, Cooper JE et al. Early manifestations and first-contact incidence of schizophrenia in different cultures. A preliminary report on the initial evaluation phase of the WHO collaborative study on determinants of outcome of severe mental disorders. Psychol Med 1986; 16: 909-928.
2. Shergill SS, Murray RM, McGuire PK. Auditory hallucinations: a review of psychological treatments. Schizophr Res 1998; 32: 137-150.
3. Copolov D, Trauer T, Mackinnon A. On the non-significance of internal versus external auditory hallucinations. Schizophr Res 2004; 69: 1-6.
4. Homan P, Kindler J, Federspiel A, Flury R, Hubl D, Hauf M et al. Muting the voice: a case of arterial spin labeling-monitored transcranial direct current stimulation treatment of auditory verbal hallucinations. Am J Psychiatry 2011; 168: 853-854.
5. Hoffman RE, Boutros NN, Berman RM, Roessler E, Belger A, Krystal JH et al. Transcranial magnetic stimulation of left temporoparietal cortex in three patients reporting hallucinated 'voices'. Biol Psychiatry 1999; 46: 130-132.
6. Hoffman RE, Boutros NN, Hu S, Berman RM, Krystal JH, Charney DS. Transcranial magnetic stimulation and auditory hallucinations in schizophrenia. Lancet 2000; 355: 1073-1075.
7. Saba G, Verdon CM, Kalalou K, Rocamora JF, Dumortier G, Benadhira R et al. Transcranial magnetic stimulation in the treatment of schizophrenic symptoms: a double blind sham controlled study. J Psychiatr Res 2006; 40: 147-152.
8. Vercammen A, Knegtering H, Bruggeman R, Westenbroek HM, Jenner JA, Slooff CJ et al. Effects of bilateral repetitive transcranial magnetic stimulation on treatment resistant auditory-verbal hallucinations in schizophrenia: a randomized controlled trial. Schizophr Res 2009; 114: 172-179.
9. Loo CK, Sainsbury K, Mitchell P, Hadzi-Pavlovic D, Sachdev PS. A sham-controlled trial of left and right temporal rTMS for the treatment of auditory hallucinations. Psychol Med 2010; 40: 541-546.
10. Rosa MO, Gattaz WF, Rosa MA, Rumi DO, Tavares H, Myczkowski M et al. Effects of repetitive transcranial magnetic stimulation on auditory hallucinations refractory to clozapine. J Clin Psychiatry 2007; 68: 1528-1532.
11. Chibbaro G, Daniele M, Alagona G, Di Pasquale C, Cannavo M, Rapisarda V et al. Repetitive transcranial magnetic stimulation in schizophrenic patients reporting auditory hallucinations. Neurosci Lett 2005; 383: 54-57.
12. Brunelin J, Poulet E, Bediou B, Kallel L, Dalery J, D'Amato T et al. Low frequency repetitive transcranial magnetic stimulation improves source monitoring deficit in hallucinating patients with schizophrenia. Schizophr Res 2006; 81: 41-45.
13. Lee SH, Kim W, Chung YC, Jung KH, Bahk WM, Jun TY et al. A double blind study showing that two weeks of daily repetitive TMS over the left or right temporoparietal cortex reduces symptoms in patients with schizophrenia who are having treatment-refractory auditory hallucinations. Neurosci Lett 2005; 376: 177-181.
14. Hoffman RE, Gueorguieva R, Hawkins KA, Varanko M, Boutros NN, Wu YT et al. Temporoparietal transcranial magnetic stimulation for auditory hallucinations: safety, efficacy and moderators in a fifty patient sample. Biol Psychiatry 2005; 58: 97-104.
15. Hoffman RE, Hampson M, Wu K, Anderson AW, Gore JC, Buchanan RJ et al. Probing the pathophysiology of auditory/verbal hallucinations by combining functional magnetic resonance imaging and transcranial magnetic stimulation. Cereb Cortex 2007; 17: 2733-2743.
16. Poulet E, Brunelin J, Bediou B, Bation R, Forgeard L, Dalery J et al. Slow transcranial magnetic stimulation can rapidly reduce resistant auditory hallucinations in schizophrenia. Biol Psychiatry 2005; 57: 188-191.
17. McIntosh AM, Semple D, Tasker K, Harrison LK, Owens DG, Johnstone EC et al. Transcranial magnetic stimulation for auditory hallucinations in schizophrenia. Psychiatry Res 2004; 127: 9-17.
18. Jandl M, Steyer J, Weber M, Linden DE, Rothmeier J, Maurer K et al. Treating auditory hallucinations by transcranial magnetic stimulation: a randomized controlled cross-over trial. Neuropsychobiology 2006; 53: 63-69.
19. Schonfeldt-Lecuona C, Gron G, Walter H, Buchler N, Wunderlich A, Spitzer M et al. Stereotaxic rTMS for the treatment of auditory hallucinations in schizophrenia. Neuroreport 2004; 15: 1669-1673.
20. Fitzgerald PB, Benitez J, Daskalakis JZ, Brown TL, Marston NA, de Castella A et al. A double-blind sham-controlled trial of repetitive transcranial magnetic stimulation in the treatment of refractory auditory hallucinations. J Clin Psychopharmacol 2005; 25: 358-362.
21. Sommer IE, de Weijer AD, Daalman K, Neggers SF, Somers M, Kahn RS et al. Can fMRI-guidance improve the efficacy of rTMS treatment for auditory verbal hallucinations? Schizophr Res 2007; 93: 406-408.
22. Slotema CW, Blom JD, de Weijer AD, Diederen KM, Goekoop R, Looijestijn J et al. Can low-frequency repetitive transcranial magnetic stimulation really relieve medication-resistant auditory verbal hallucinations? Negative results from a large randomized controlled trial. Biol Psychiatry 2011; 69: 450-456.
23. Demeulemeester M, Amad A, Bubrovszky M, Pins D, Thomas P, Jardri R. What is the real effect of 1-Hz repetitive transcranial magnetic stimulation on hallucinations? Controlling for publication bias in neuromodulation trials. Biol Psychiatry 2012; 71: e15-e16.
24. Kindler J, Homan P, Jann K, Federspiel A, Flury R, Hauf M et al. Reduced neuronal activity in language-related regions after transcranial magnetic stimulation therapy for auditory verbal hallucinations. Biol Psychiatry; e-pub ahead of print 26 July 2012; doi:10.1016/j.biopsych.2012.06.019.
25. Liddle PF, Friston KJ, Frith CD, Hirsch SR, Jones T, Frackowiak RS. Patterns of cerebral blood flow in schizophrenia. Br J Psychiatry 1992; 160: 179-186.
26. Gur RE, Mozley PD, Resnick SM, Mozley LH, Shtasel DL, Gallacher F et al. Resting cerebral glucose metabolism in first-episode and previously treated patients with schizophrenia relates to clinical features. Arch Gen Psychiatry 1995; 52: 657-667.
27. Lahti AC, Weiler MA, Holcomb HH, Tamminga CA, Carpenter WT, McMahon R. Correlations between rCBF and symptoms in two independent cohorts of drug-free patients with schizophrenia. Neuropsychopharmacology 2006; 31: 221-230.
28. Huang YZ, Edwards MJ, Rounis E, Bhatia KP, Rothwell JC. Theta burst stimulation of the human motor cortex. Neuron 2005; 45: 201-206.
29. Nyffeler T, Cazzoli D, Hess CW, Muri RM. One session of repeated parietal theta burst stimulation trains induces long-lasting improvement of visual neglect. Stroke 2009; 40: 2791-2796.
30. Kindler J, Schumacher R, Cazzoli D, Gutbrod K, Koenig M, Nyffeler T etal. Theta burst stimulation over the right broca's homologue induces improvement of naming in aphasic patients. Stroke 2012; 43: 2175-2179.
31. Viviani R, Sim EJ, Lo H, Beschoner P, Osterfeld N, Maier C et al. Baseline brain perfusion and the serotonin transporter promoter polymorphism. Biol Psychiatry 2010; 67: 317-322.
32. Jann K, Koenig T, Dierks T, Boesch C, Federspiel A. Association of individual resting state EEG alpha frequency and cerebral blood flow. Neuroimage 51: 365-372.
33. Horn H, Federspiel A, Wirth M, Muller TJ, Wiest R, Wang JJ etal. Structural and metabolic changes in language areas linked to formal thought disorder. Br J Psychiatry 2009; 194: 130-138.
34. Xu G, Rowley HA, Wu G, Alsop DC, Shankaranarayanan A, Dowling M etal. Reliability and precision of pseudo-continuous arterial spin labeling perfusion MRI on 3.0 T and comparison with 15O-water PET in elderly subjects at risk for Alzheimer's disease. NMR Biomed 2010; 23: 286-293.
35. Hoffman RE, Hawkins KA, Gueorguieva R, Boutros NN, Rachid F, Carroll K et al. Transcranial magnetic stimulation of left temporoparietal cortex and medication-resistant auditory hallucinations. Arch Gen Psychiatry 2003; 60: 49-56.
36. Kay SR, Opler LA, Lindenmayer JP. Reliability and validity of the positive and negative syndrome scale for schizophrenics. Psychiatry Res 1988; 23: 99-110.
37. Oldfield RC. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 1971; 9: 97-113.
38. Wang J, Rao H, Wetmore GS, Furlan PM, Korczykowski M, Dinges DF et al. Perfusion functional MRI reveals cerebral blood flow pattern under psychological stress. Proc Natl Acad Sci USA 2005; 102:17804-17809.
39. Homan P, Kindler J, Hubl D, Dierks T. Auditory verbal hallucinations: imaging, analysis, and intervention. Eur Arch Psychiatry Clin Neurosci 2012; e-pub ahead of print 2 September 2012; doi:10.1007/s00406-012-0355-2.
40. Brett M, Anton JL, Valabregue R, Poline JB. Region of interest analysis using an SPM toolbox. 8th International Conference on Functional Mapping of the Human Brain, vol. 16: Sendai, Japan, 2002.
41. Federspiel A, Muller TJ, Horn H, Kiefer C, Strik WK. Comparison of spatial and temporal pattern for fMRI obtained with BOLD and arterial spin labeling. J Neural Transm 2006; 113: 1403-1415.
42. Hickok G, Poeppel D. The cortical organization of speech processing. Nat Rev Neurosci 2007; 8: 393-402.
43. Hickok G, Okada K, Serences JT. Area Spt in the human planum temporale supports sensory-motor integration for speech processing. J Neurophysiol 2009; 101: 2725-2732.
44. Hashimoto R, Lee K, Preus A, McCarley RW, Wible CG. An fMRI study of functional abnormalities in the verbal working memory system and the relationship to clinical symptoms in chronic schizophrenia. Cereb Cortex 2010; 20: 46-60.
45. Schutter DJ, van Honk JA. Standardized motor threshold estimation procedure for transcranial magnetic stimulation research. JECT2006; 22:176-178.
46. Rossi S, Hallett M, Rossini PM, Safety Pascual-Leone A. Ethical considerations, and application guidelines for the use of transcranial magnetic stimulation in clinical practice and research. Clin Neurophysiol 2009; 120: 2008-2039.
47. Sack AT, Cohen Kadosh R, Schuhmann T, Moerel M, Walsh V, Goebel R. Optimizing functional accuracy of TMS in cognitive studies: a comparison of methods. J Cogn Neurosci 2009; 21: 207-221.
48. David AS. The neuropsychological origin of auditory hallucinations. In: David AS, Cutting JC (eds). Neuropsychology of Schizophrenia. Erlbaum: Hove, UK, 1994, pp 269-313.
49. McGuire PK, Silbersweig DA, Wright I, Murray RM, David AS, Frackowiak RS et al. Abnormal monitoring of inner speech: a physiological basis for auditory hallucinations. Lancet 1995; 346: 596-600.
50. Hubl D, Koenig T, Strik W, Federspiel A, Kreis R, Boesch C et al. Pathways that make voices: white matter changes in auditory hallucinations. Arch Gen Psychiatry 2004; 61: 658-668.
51. Hubl D, Koenig T, Strik WK, Garcia LM, Dierks T. Competition for neuronal resources: how hallucinations make themselves heard. Br J Psychiatry 2007; 190: 57-62.
52. Aleman A, Sommer IE, Kahn RS. Efficacy of slow repetitive transcranial magnetic stimulation in the treatment of resistant auditory hallucinations in schizophrenia: a metaanalysis. J Clin Psychiatry 2007; 68: 416-421.
53. Behrendt RP, Young C. Hallucinations in schizophrenia, sensory impairment, and brain disease: a unifying model. Behav Brain Sci 2004; 27: 771-787; discussion 787-830.