Characterisation of the Virulence Factors and Genetic Types of Methicillin Susceptible Staphylococcus aureus from Patients and Healthy Individuals

Indian Journal of Microbiology

Volumn 52, Issue 4, 2012, Pages 593-600

  Lim, King Ting ^a   Hanifah, Yasmin Abu ^a   Yusof, Mohd Yasim Mohd ^a   Thong, Kwai Lin ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

PFGE; spa and agr; Staphylococcus aureus; Virulence genes

Indexed keywords

BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS AUREUS;

EID: 84870788273     PISSN: 00468991     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12088-012-0286-7     Document Type: Article

References (29)

1. Plata K, Rosato AE, Wegrzyn G (2009) Staphylococcus aureus as an infectious agent: overview of biochemistry and molecular genetics of its pathogenicity. Acta Biochim Pol 56: 597-612.
2. Gordon RJ, Lowy FD (2008) Pathogenesis of methicillin-resistant Staphylococcus aureus infection. Clin Infect Dis 46: S350-S359.
3. Ortega E, Abriouel H, Lucas R, Galvez A (2010) Multiple roles of Staphylococcus aureus enterotoxins: pathogenicity, superantigenic activity, and correlation to antibiotic resistance. Toxins 2: 2117-2131.
4. Argudin MA, Mendoza MC, Rodicio MR (2010) Food poisoning and Staphylococcus aureus enterotoxins. Toxins 2: 1751-1773.
5. Traber KE, Lee E, Benson S, Corrigan R, Cantera M, Shopsin B, Novick RP (2008) Agr function in clinical Staphylococcus aureus strains. Microbiol 154: 2265-2274.
6. Baranovich T, Zarake H, Shabana II, Nevzorova V, Turcutyuicov V, Suzuki H (2010) Molecular characterization and susceptibility of methicillin-resistant and methicillin-susceptible Staphylococcus aureus isolates from hospitals and the community in Vladivostok, Russia. Clin Microbiol Infect 16: 575-582.
7. Chonngtrakool P, Ito T, Ma XX, Kondo Y, Trakulsomboon S, Tiensasitorn C, Jamklang M (2006) Staphylococcal cassette chromosome mec (SCCmec) typing of methicillin-resistant Staphylococcus aureus strains isolated in 11 Asian countries: a proposal for a new nomenclature for SCCmec elements. Antimicrob Agents Chemother 50: 1001-1012.
8. Mitani N, Koizumi A, Sano R, Masutani T, Murukawa K, Mikasa K, Okamoto Y (2005) Molecular typing of methicillin-resistant Staphylococcus aureus by PCR-RFLP and its usefulness in an epidemiological study of an outbreak. Jpn J Infect Dis 58: 250-252.
9. Thong KL, June J, Liew FY, Yusof MY, Hanifah YA (2009) Antibiograms and molecular subtypes of methicillin-resistant Staphylococcus aureus in local teaching hospital, Malaysia. J Microbiol Biotechnol 19: 1265-1270.
10. Ghaznavi-Rad E, Shamsudin MN, Sekawi Z, Khoon LY, Azoz MN, Hamat RA, Othman N, Chong PP, van Belkum A, Ghasemzadeh-Moghaddam H, Neela V (2010) Predominance and emergence of clones of hospital-acquired methicillin-resistant Staphylococcus aureus in Malaysia. J Clin Microbiol 48: 867-872.
11. Himabindu M, Muthamilselvan DS, Bishi DK, Verma RS (2009) Molecular analysis of coagulase gene polymorphism in clinical isolates of methicillin resistant Staphylococcus aureus by restriction fragment length polymorphism based genotyping. Am J Infect Dis 5: 170-176.
12. Deurenburg RH, Vink C, Kalenic S, Friedrich AW, Bruggeman CA, Stobberingh EE (2007) The molecular evolution of methicillin-resistant Staphylococcus aureus. Clin Microbiol Infect Dis 13: 222-235.
13. Ghasemzadeh-Moghaddam H, Ghaznavi-Rad E, Sekawi Z, Liew YK, Aziz MN, Hamat RA, Melles DC, van Belkum A, Shamsudin MN, Neela V (2011) Methicillin-susceptible Staphylococcus aureus from clinical and community sources are genetically diverse. Intern J Med Microbiol 301: 347-353.
14. Jarraud S, Mougel C, Thioulouse J, Lina G, Meugnier H, Forey F, Nesmw X, Etienne J, Vandenesh F (2002) Relationship between Staphylococcus aureus genetic background, virulence factors, agr types (alleles), and human disease. Infect Immun 70: 631-641.
15. Hisata K, Kuwahara-Arai K, Yamanoto M, Ito T, Nakatomi Y, Cui L, Baba T, Terasawa M, Sotozono C, Kimoshita S, Yamashiro Y, Hiratmasu K (2005) Dissemination of methicillin-resistant Staphylococcus among healthy Japanese children. J Clin Microbiol 43: 3364-3372.
16. Lina G, Piemont Y, Godail-Gamot F, Bes M, Peter MO, Gauduchon V, Vandenesch F, Etienne J (1999) Involvement of panton-valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia. Clin Infect Dis 29: 1129-1133.
17. Kumar JD, Negi YK, Gaur A, Khanna D (2009) Detection of virulence genes in Staphylococcus aureus strains from paper currency. Intern J Infect Dis 13: e450-e455.
18. Moore PCL, Lindsay JA (2001) Genetic variation among hospital strains of methicillin-sensitive Staphylococcus aureus: evidence for horizontal transfer of virulence genes. J Clin Microbiol 39: 2767-2860.
19. Arciola CR, Campoccia D, Gemberini S, Baldassarri L, Montanaro L (2005) Prevalence of cna, fnbA and fnbB adhesin genes among Staphylococcus aureus isolates from orthopaedic infections associated to different types of implant. FEMS Microbiol Lett 246: 81-86.
20. Lina G, Boutitie F, Tristan A, Bes M, Etienne J, Vandenesch F (2003) Bacterial competition for human nasal cavity colonization: role of staphylococcal agr alleles. Appl Environ Microbiol 69: 18-23.
21. Hookey JV, Richardson JF, Cookson BD (1998) Molecular typing of Staphylococcus aureus based on PCR restriction fragment length polymorphism and DNA sequence analysis of the coagulase gene. J Clin Microbiol 36: 1083-1089.
22. Harmsen D, Clause H, Witte W, Rothaganger J, Claus H, Turnwald D, Vogel U (2003) Typing of methicillin-resistant Staphylococcus aureus in a University Hospital Setting by using novel software for spa repeat determination and database management. J Clin Microbiol 41: 5442-5448.
23. Shore AC, Rossney AS, Kinnevey PM, Brennam OM, Creamer E, Sherlock O, Dolan A, Cunney R, Sullivan DJ, Goering RV, Humphreys H, Coleman DC (2010) Enhanced discrimination of highly clonal ST22-methicillin-resistant Staphylococcus aureus IV strains achieved by combining spa, dru, and pulsed-field gel electrophoresis typing data. J Clin Microbiol 48: 1839-1852.
24. Hussain A, Robinson G, Malkin J, Duthie M, Kearns A, Perera N (2007) Purpura fulminans in a child secondary to panton-valentine leukocidin-producing Staphylococcus aureus. J Med Microbiol 56: 1407-1409.
25. Kikuchi K, Takahashi N, Piao C, Totsuka K, Nishida H, Uchiyama T (2003) Molecular epidemiology of methicillin-resistant Staphylococcus aureus strains causing neonatal toxic shock syndrome-like exanthematous disease in neonatal and perinatal wards. J Clin Microbiol 41: 3001-3006.
26. Kravitz GR, Dries DJ, Peterson ML, Schlievert PM (2005) Purpura fulminans due to Staphylococcus aureus. Clin Infect Dis 40: 941-947.
27. Perez-Vazquez M, Vindel A, Marcos C, Oteo J, Cuevas O, Trincado P, Bautista V, Grundmann H, Campos J (2008) Spread of invasive Spanish Staphylococcus aureus spa-type t067 associated with a high prevalence of the aminoglycoside-modifying enzyme gene ant(4′)-Ia and the efflux pump genes msrA/msrB. J Antimicrob Agents 63: 21-31.
28. Vasanthakumari N, Subeh A, Alshrari D, Ghaznavi-Rad E, Moghaddam A, van Belkum A, Alreshidi MA, Selamat N, Shamsudin MN (2009) Highly dynamic transient colonization by Staphylococcus aureus in healthy Malaysian student. J Med Microbiol 58: 1531-1532.
29. Hu DL, Omoe K, Inoue F, Kasai T, Yasujima M, Shinagawa K, Nakane A (2008) Comparative prevalence of superantigenic toxin genes in methicillin-resistant and methicillin-susceptible Staphylococcus aureus isolates. J Med Microbiol 57: 1106-1112.