Blocking muscarinic receptors in the olfactory bulb impairs performance on an olfactory short term memory task

Frontiers in Behavioral Neuroscience

Volumn , Issue AUGUST, 2012, Pages

  Devore, Sasha ^a   Manella, Laura C ^a   Linster, Christiane ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUSCARINIC RECEPTOR; SCOPOLAMINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; MALE; NONHUMAN; OLFACTORY BULB; OLFACTORY MEMORY; RAT; REWARD; SHORT TERM MEMORY; SIGNAL TRANSDUCTION; TASK PERFORMANCE;

EID: 84870780806     PISSN: 16625153     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Castillo PE, Carleton A, Vincent JD, Lledo PM (1999) Multiple and opposing roles of cholinergic transmission in the main olfactory bulb. J Neurosci 19:9180-9191.
2. Chaudhury D, Escanilla O, Linster C (2009) Bulbar acetylcholine enhances neural and perceptual odor discrimination. The Journal of Neuroscience 29:52-60.
3. Cleland TA, Linster C (2005) Computation in the Olfactory System. Chemical Senses 30:801-813.
4. Cleland TA, Morse A, Yue E, Linster C (2002) Behavioral models of odor similarity. Behavioral Neuroscience 116:222-231.
5. David FO, Hugues E, Cenier T, Fourcaud-Trocmé N, Buonviso N (2009) Specific Entrainment of Mitral Cells during Gamma Oscillation in the Rat Olfactory Bulb. PLoS Comput Biol 5:e1000551.
6. De Rosa E, Hasselmo ME (2000) Muscarinic cholinergic neuromodulation reduces proactive interference between stored odor memories during associative learning in rats. Behavioral Neuroscience 114:32-41.
7. Ghatpande AS, Sivaraaman K, Vijayaraghavan S (2006) Store calcium mediates cholinergic effects on mIPSCs in the rat main olfactory bulb. J Neurophysiol 95:1345-1355.
8. Hasselmo M, Giocomo L (2006) Cholinergic modulation of cortical function. Journal of Molecular Neuroscience 30:133-135.
9. Hasselmo M, Anderson BP, Bower JM (1992) Cholinergic modulation of cortical associative memory function. Journal of Neurophysiology 67:1230-1246.
10. Heimer L, Zahm DS, Schmued LC (1990) The basal forebrain projection to the region of the nuclei gemini in the rat; a combined light and electron microscopic study employing horseradish peroxidase, fluorescent tracers and Phaseolus vulgaris-leucoagglutinin. Neuroscience 34:707-731.
11. Hunter A, Murray T (1989) Cholinergic mechansims in a simple test of olfactory learning in the rat. Psychopharmacology 99:270-275.
12. Linster C, Cleland TA (2002) Cholinergic modulation of sensory representations in the olfactory bulb. Neural Networks 15:709-717.
13. Linster C, Cleland TA (2010) Decorrelation of odor representations via spike timing-dependent plasticity. Frontiers in Computational Neuroscience 4.
14. Linster C, Garcia P, Hasselmo M, Baxter M (2001) Selective loss of cholinergic neurons projecting to the olfactory system increases perceptual generalization between similar, but not dissimilar, odorants. Behavioral Neuroscience 115:826-833.
15. Mandairon N, Ferretti CJ, Stack CM, Rubin DB, Cleland TA, Linster C (2006) Cholinergic modulation in the olfactory bulb influences spontaneous olfactory discrimination in adult rats. European Journal of Neuroscience 24:3234-3244.
16. Mesulam MM, Mufson EJ, Levey AI, Wainer BH (1983) Cholinergic in nervation of cortex by the basal forebrain: Cytochemistry and cortical connections of the septal area, diagonal band nuclei, nucleus basalis (Substantia innominata), and hypothalamus in the rhesus monkey. The Journal of Comparative Neurology 214:170-197.
17. Pressler RT, Inoue T, Strowbridge BW (2007a) Muscarinic receptor activation modulates granule cell excitability and potentiates inhibition onto mitral cells in the rat olfactory bulb. J Neurosci 27:10969-10981.
18. Pressler RT, Inoue T, Strowbridge BW (2007b) Muscarinic R 399 eceptor Activation Modulates Granule Cell Excitability and Potentiates Inhibition onto Mitral Cells in the Rat Olfactory Bulb. The Journal of Neuroscience 27:10969-10981.
19. Ravel N, Elaagouby A, Gervais R (1994) Scopolamine injection into the olfactory bulb impairs short-term olfactory memory in rats. Behavioral Neuroscience 108:317-324.
20. Sarter M, Bruno JP (1997) Cognitive functions of cortical acetylcholine: toward a unifying hypothesis. Brain Res Brain Res Rev 23:28-46.
21. Sarter M, Hasselmo ME, Bruno JP, Givens B (2005) Unraveling the attentional functions of cortical cholinergic inputs: interactions between signal-driven and cognitive modulation of signal detection. Brain Research Reviews 48:98-111.
22. Yu AJ, Dayan P (2005) Uncertainty, Neuro modulation, and Attention. Neuron 46:681-692.