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Volumn 7, Issue 12, 2012, Pages

Prevention of Vaginal SHIV Transmission in Macaques by a Coitally-Dependent Truvada Regimen

Author keywords

[No Author keywords available]

Indexed keywords

EMTRICITABINE; EMTRICITABINE PLUS TENOFOVIR DISOPROXIL; PLACEBO; TENOFOVIR; VIRUS DNA; VIRUS RNA;

EID: 84870748389     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0050632     Document Type: Article
Times cited : (63)

References (40)
  • 1
    • 78650549662 scopus 로고    scopus 로고
    • Preexposure chemoprophylaxis for HIV prevention in men who have sex with men
    • Grant RM, Lama JR, Anderson PL, McMahan V, Liu AY, et al. (2010) Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med 363: 2587-2599.
    • (2010) N Engl J Med , vol.363 , pp. 2587-2599
    • Grant, R.M.1    Lama, J.R.2    Anderson, P.L.3    McMahan, V.4    Liu, A.Y.5
  • 2
    • 84864527306 scopus 로고    scopus 로고
    • Antiretroviral Preexposure Prophylaxis for Heterosexual HIV Transmission in Botswana
    • July 11, 2012 (10.1056/NEJMoa1110711)
    • Thigpen MC, Kebaabetswe PM, Paxton LA, Smith DK, Rose CE, et al. (2012) Antiretroviral Preexposure Prophylaxis for Heterosexual HIV Transmission in Botswana. N Engl J Med July 11, 2012 (10.1056/NEJMoa1110711).
    • (2012) N Engl J Med
    • Thigpen, M.C.1    Kebaabetswe, P.M.2    Paxton, L.A.3    Smith, D.K.4    Rose, C.E.5
  • 3
    • 84864505868 scopus 로고    scopus 로고
    • Antiretroviral Prophylaxis for HIV Prevention in Heterosexual Men and Women
    • 10.1056/NEJMoa1108524
    • Baeten JM, Donnell D, Ndase P, Mugo NR, Campbell JD, et al. (2012) Antiretroviral Prophylaxis for HIV Prevention in Heterosexual Men and Women. N Engl J Med 10.1056/NEJMoa1108524.
    • (2012) N Engl J Med
    • Baeten, J.M.1    Donnell, D.2    Ndase, P.3    Mugo, N.R.4    Campbell, J.D.5
  • 4
    • 84864507852 scopus 로고    scopus 로고
    • Preexposure Prophylaxis for HIV Infection among African Women
    • 10.1056/NEJMoa1202614
    • Van Damme L, Corneli A, Ahmed K, Agot K, Lombaard J, et al. (2012) Preexposure Prophylaxis for HIV Infection among African Women. N Engl J Med 10.1056/NEJMoa1202614.
    • (2012) N Engl J Med
    • van Damme, L.1    Corneli, A.2    Ahmed, K.3    Agot, K.4    Lombaard, J.5
  • 5
    • 33745937659 scopus 로고    scopus 로고
    • Repetitive exposures with simian/human immunodeficiency viruses: strategy to study HIV pre-clinical interventions in non-human primates
    • Kim C, Adams D, Bashirian S, Butera S, Folks T, et al. (2006) Repetitive exposures with simian/human immunodeficiency viruses: strategy to study HIV pre-clinical interventions in non-human primates. J Med Primatol 35: 210-216.
    • (2006) J Med Primatol , vol.35 , pp. 210-216
    • Kim, C.1    Adams, D.2    Bashirian, S.3    Butera, S.4    Folks, T.5
  • 6
    • 19944428117 scopus 로고    scopus 로고
    • Multiple vaginal exposures to low doses of R5 simian-human immunodeficiency virus: strategy to study HIV preclinical interventions in nonhuman primates
    • Otten RA, Adams DR, Kim CN, Jackson E, Pullium JK, et al. (2005) Multiple vaginal exposures to low doses of R5 simian-human immunodeficiency virus: strategy to study HIV preclinical interventions in nonhuman primates. J Infect Dis 19: 164-173.
    • (2005) J Infect Dis , vol.19 , pp. 164-173
    • Otten, R.A.1    Adams, D.R.2    Kim, C.N.3    Jackson, E.4    Pullium, J.K.5
  • 7
    • 39849100140 scopus 로고    scopus 로고
    • Prevention of rectal SHIV transmission in macaques by daily or intermittent prophylaxis with emtricitabine and tenofovir PLoS Med
    • García-Lerma JG, Otten RA, Qari SH, Jackson E, Cong M, et al. (2008) Prevention of rectal SHIV transmission in macaques by daily or intermittent prophylaxis with emtricitabine and tenofovir PLoS Med. 5: e28.
    • (2008) , vol.5
    • García-Lerma, J.G.1    Otten, R.A.2    Qari, S.H.3    Jackson, E.4    Cong, M.5
  • 9
    • 79551578453 scopus 로고    scopus 로고
    • Early events in sexual transmission of HIV and SIV and opportunities for interventions
    • Haase AT, (2011) Early events in sexual transmission of HIV and SIV and opportunities for interventions. Annu Rev Med 62: 127-139.
    • (2011) Annu Rev Med , vol.62 , pp. 127-139
    • Haase, A.T.1
  • 10
    • 0034051289 scopus 로고    scopus 로고
    • Simian immunodeficiency virus rapidly penetrates the cervicovaginal mucosa after intravaginal inoculation and infects intraepithelial dendritic cells
    • Hu J, Gardner MB, Miller CJ, (2000) Simian immunodeficiency virus rapidly penetrates the cervicovaginal mucosa after intravaginal inoculation and infects intraepithelial dendritic cells. J Virol 74: 6087-6095.
    • (2000) J Virol , vol.74 , pp. 6087-6095
    • Hu, J.1    Gardner, M.B.2    Miller, C.J.3
  • 12
    • 53549135475 scopus 로고    scopus 로고
    • A new strategy to understand how HIV infects women: identification of a window of vulnerability during the menstrual cycle
    • Wira CR, Fahey JV, (2008) A new strategy to understand how HIV infects women: identification of a window of vulnerability during the menstrual cycle. AIDS 22: 1909-1917.
    • (2008) AIDS , vol.22 , pp. 1909-1917
    • Wira, C.R.1    Fahey, J.V.2
  • 13
    • 83155177076 scopus 로고    scopus 로고
    • Penetration of tenofovir and emtricitabine in mucosal tissues: implications for prevention of HIV-1 transmission
    • Patterson KB, Prince HA, Kraft E, Jenkins AJ, Shaheen NJ, et al. (2011) Penetration of tenofovir and emtricitabine in mucosal tissues: implications for prevention of HIV-1 transmission. Sci Transl Med 3: 112re114.
    • (2011) Sci Transl Med , vol.3
    • Patterson, K.B.1    Prince, H.A.2    Kraft, E.3    Jenkins, A.J.4    Shaheen, N.J.5
  • 14
    • 0019820666 scopus 로고
    • Characteristics of the menstrual cycle in nonhuman primates. IV. Timed mating in Macaca nemestrina
    • Blakley GB, Beamer TW, Dukelow WR, (1981) Characteristics of the menstrual cycle in nonhuman primates. IV. Timed mating in Macaca nemestrina. Lab Anim 15: 351-353.
    • (1981) Lab Anim , vol.15 , pp. 351-353
    • Blakley, G.B.1    Beamer, T.W.2    Dukelow, W.R.3
  • 15
    • 0031958939 scopus 로고    scopus 로고
    • Vaginal transmission of SIV: assessing infectivity and hormonal influences in macaques inoculated with cell-free and cell-associated viral stocks
    • Sodora DL, Gettie A, Miller CJ, Marx PA (1998) Vaginal transmission of SIV: assessing infectivity and hormonal influences in macaques inoculated with cell-free and cell-associated viral stocks. AIDS Res Hum Retroviruses Suppl 1: S119-123.
    • (1998) AIDS Res Hum Retroviruses Suppl , vol.1
    • Sodora, D.L.1    Gettie, A.2    Miller, C.J.3    Marx, P.A.4
  • 16
    • 79959938249 scopus 로고    scopus 로고
    • High susceptibility to repeated, low-dose, vaginal SHIV exposure late in the luteal phase of the menstrual cycle of pigtail macaques
    • Vishwanathan SA, Guenthner PC, Lin CY, Dobard C, Sharma S, et al. (2011) High susceptibility to repeated, low-dose, vaginal SHIV exposure late in the luteal phase of the menstrual cycle of pigtail macaques. J Acquir Immune Defic Syndr 57: 261-264.
    • (2011) J Acquir Immune Defic Syndr , vol.57 , pp. 261-264
    • Vishwanathan, S.A.1    Guenthner, P.C.2    Lin, C.Y.3    Dobard, C.4    Sharma, S.5
  • 18
    • 66849135265 scopus 로고    scopus 로고
    • Effect of mobile phase pH and organic content on LC-MS analysis of nucleoside and nucleotide HIV reverse transcriptase inhibitors
    • Kuklenyik Z, Martin A, Pau CP, Garcia-Lerma JG, Heneine W, et al. (2009) Effect of mobile phase pH and organic content on LC-MS analysis of nucleoside and nucleotide HIV reverse transcriptase inhibitors. J Chromatogr Sci 47: 365-372.
    • (2009) J Chromatogr Sci , vol.47 , pp. 365-372
    • Kuklenyik, Z.1    Martin, A.2    Pau, C.P.3    Garcia-Lerma, J.G.4    Heneine, W.5
  • 19
    • 34250204898 scopus 로고    scopus 로고
    • Evidence and possible consequences of the phosphorylation of nucleoside reverse transcriptase inhibitors in human red blood cells
    • Durand-Gasselin L, Da Silva D, Benech H, Pruvost A, Grassi J, (2007) Evidence and possible consequences of the phosphorylation of nucleoside reverse transcriptase inhibitors in human red blood cells. Antimicrob Agents Chemother 51: 2105-2111.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 2105-2111
    • Durand-Gasselin, L.1    Da Silva, D.2    Benech, H.3    Pruvost, A.4    Grassi, J.5
  • 20
    • 72049125123 scopus 로고    scopus 로고
    • On-line coupling of anion exchange and ion pair chromatography for measurement of intracellular triphosphate metabolites of reverse transcriptase inhibitors
    • Kuklenyik Z, Martin A, Pau C, Holder A, Youngpairoj AS, et al. (2009) On-line coupling of anion exchange and ion pair chromatography for measurement of intracellular triphosphate metabolites of reverse transcriptase inhibitors. J Chromatogr B Analyt Technol Biomed Life Sci 877: 3659-3666.
    • (2009) J Chromatogr B Analyt Technol Biomed Life Sci , vol.877 , pp. 3659-3666
    • Kuklenyik, Z.1    Martin, A.2    Pau, C.3    Holder, A.4    Youngpairoj, A.S.5
  • 21
    • 70349736171 scopus 로고    scopus 로고
    • Complete protection from repeated vaginal SHIV exposures in macaques by a topical gel containing tenofovir alone or with emtricitabine
    • Parikh U, Dobard C, Sharma S, Cong M, Jia H, et al. (2009) Complete protection from repeated vaginal SHIV exposures in macaques by a topical gel containing tenofovir alone or with emtricitabine. J Virol 83: 10358-10365.
    • (2009) J Virol , vol.83 , pp. 10358-10365
    • Parikh, U.1    Dobard, C.2    Sharma, S.3    Cong, M.4    Jia, H.5
  • 22
    • 33748988204 scopus 로고    scopus 로고
    • Chemoprophylaxis with tenofovir disoproxil fumarate provided partial protection against infection with simian human immunodeficiency virus in macaques given multiple virus challenges
    • Subbarao S, RA Otten RA, Ramos A, Kim C, Jackson E, et al. (2006) Chemoprophylaxis with tenofovir disoproxil fumarate provided partial protection against infection with simian human immunodeficiency virus in macaques given multiple virus challenges. J Infect Dis 194: 904-911.
    • (2006) J Infect Dis , vol.194 , pp. 904-911
    • Subbarao, S.1    Otten, R.A.R.A.2    Ramos, A.3    Kim, C.4    Jackson, E.5
  • 23
    • 0032924466 scopus 로고    scopus 로고
    • Correlation of human immunodeficiency virus type 1 RNA levels in blood and the female genital tract
    • Hart CE, Lennox JL, Pratt-Palmore M, Wright TC, Schinazi RF, et al. (1999) Correlation of human immunodeficiency virus type 1 RNA levels in blood and the female genital tract. J Infect Dis 179: 871-882.
    • (1999) J Infect Dis , vol.179 , pp. 871-882
    • Hart, C.E.1    Lennox, J.L.2    Pratt-Palmore, M.3    Wright, T.C.4    Schinazi, R.F.5
  • 24
    • 34548267289 scopus 로고    scopus 로고
    • Antiretroviral drug exposure in the female genital tract: implications for oral pre- and post-exposure prophylaxis
    • Dumond JB, Yeh RF, Patterson KB, Corbett AH, Jung BH, et al. (2007) Antiretroviral drug exposure in the female genital tract: implications for oral pre- and post-exposure prophylaxis. AIDS 21: 1899-1907.
    • (2007) AIDS , vol.21 , pp. 1899-1907
    • Dumond, J.B.1    Yeh, R.F.2    Patterson, K.B.3    Corbett, A.H.4    Jung, B.H.5
  • 25
    • 0017618374 scopus 로고
    • Sex hormones correlated with sex skin swelling and rectal temperature during the menstrual cycle of the pigtail macaque (Macaca nemestrina)
    • Steiner RA, Schiller HS, Illner P, Blandau R, Gale CC, (1977) Sex hormones correlated with sex skin swelling and rectal temperature during the menstrual cycle of the pigtail macaque (Macaca nemestrina). Lab Anim Sci 27: 217-221.
    • (1977) Lab Anim Sci , vol.27 , pp. 217-221
    • Steiner, R.A.1    Schiller, H.S.2    Illner, P.3    Blandau, R.4    Gale, C.C.5
  • 26
    • 0023033053 scopus 로고
    • Man versus beast: pharmacokinetic scaling in mammals
    • Mordenti J, (1986) Man versus beast: pharmacokinetic scaling in mammals. J Pharm Sci 75: 1028-1040.
    • (1986) J Pharm Sci , vol.75 , pp. 1028-1040
    • Mordenti, J.1
  • 27
    • 22344455482 scopus 로고    scopus 로고
    • Intracellular pharmacokinetics of tenofovir diphosphate, carbovir triphosphate, and lamivudine triphosphate in patients receiving triple-nucleoside regimens
    • Hawkins T, Veikley W, St Claire RL 3rd, Guyer B, Clark N, et al (2005) Intracellular pharmacokinetics of tenofovir diphosphate, carbovir triphosphate, and lamivudine triphosphate in patients receiving triple-nucleoside regimens. J Acquir Immune Defic Syndr 39: 406-411.
    • (2005) J Acquir Immune Defic Syndr , vol.39 , pp. 406-411
    • Hawkins, T.1    Veikley, W.2    St Claire 3rd, R.L.3    Guyer, B.4    Clark, N.5
  • 28
    • 20944435946 scopus 로고    scopus 로고
    • Measurement of intracellular didanosine and tenofovir phosphorylated metabolites and possible interaction of the two drugs in human immunodeficiency virus-infected patients
    • Pruvost A, Negredo E, Benech H, Theodoro F, Puig J, et al. (2005) Measurement of intracellular didanosine and tenofovir phosphorylated metabolites and possible interaction of the two drugs in human immunodeficiency virus-infected patients. Antimicrob Agents Chemother 49: 1907-1914.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 1907-1914
    • Pruvost, A.1    Negredo, E.2    Benech, H.3    Theodoro, F.4    Puig, J.5
  • 29
    • 3142717936 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic characteristics of emtricitabine support its once daily dosing for the treatment of HIV infection
    • Wang LH, Begley J, St Claire RL 3rd, Harris J, Wakeford C, et al (2004) Pharmacokinetic and pharmacodynamic characteristics of emtricitabine support its once daily dosing for the treatment of HIV infection. AIDS Res Hum Retroviruses 20: 1173-1182.
    • (2004) AIDS Res Hum Retroviruses , vol.20 , pp. 1173-1182
    • Wang, L.H.1    Begley, J.2    St Claire 3rd, R.L.3    Harris, J.4    Wakeford, C.5
  • 30
    • 80052070000 scopus 로고    scopus 로고
    • Natural substrate concentrations can modulate the prophylactic erfficacy of nucleotide HIV reverse transcriptase inhibitors
    • García-Lerma JG, Aung W, Cong ME, Zheng Q, Youngpairoj AS, et al. (2011) Natural substrate concentrations can modulate the prophylactic erfficacy of nucleotide HIV reverse transcriptase inhibitors. J Virol 85: 6610-6617.
    • (2011) J Virol , vol.85 , pp. 6610-6617
    • García-Lerma, J.G.1    Aung, W.2    Cong, M.E.3    Zheng, Q.4    Youngpairoj, A.S.5
  • 33
    • 0031959187 scopus 로고    scopus 로고
    • Effects of two progestin-only contraceptives, Depo-Provera and Norplant-II, on the vaginal epithelium of rhesus monkeys
    • Hild-Petito S, Veazey RS, Larner JM, Reel JR, Blye RP (1998) Effects of two progestin-only contraceptives, Depo-Provera and Norplant-II, on the vaginal epithelium of rhesus monkeys. AIDS Res Hum Retroviruses Suppl 1: S125-130.
    • (1998) AIDS Res Hum Retroviruses Suppl , vol.1
    • Hild-Petito, S.1    Veazey, R.S.2    Larner, J.M.3    Reel, J.R.4    Blye, R.P.5
  • 34
    • 0345360806 scopus 로고    scopus 로고
    • Progesterone implants enhance SIV vaginal transmission and early virus load
    • Marx PA, Spira AI, Gettie A, Dailey PJ, Veazey RS, et al. (1996) Progesterone implants enhance SIV vaginal transmission and early virus load. Nat Med 2: 1084-1089.
    • (1996) Nat Med , vol.2 , pp. 1084-1089
    • Marx, P.A.1    Spira, A.I.2    Gettie, A.3    Dailey, P.J.4    Veazey, R.S.5
  • 35
    • 6944244828 scopus 로고    scopus 로고
    • Abrogation of attenuated lentivirus-induced protection in rhesus macaques by administration of depo-provera before intravaginal challenge with simian immunodeficiency virus mac239
    • Abel K, Rourke T, Lu D, Bost K, McChesney MB, Miller CJ, (2004) Abrogation of attenuated lentivirus-induced protection in rhesus macaques by administration of depo-provera before intravaginal challenge with simian immunodeficiency virus mac239. J Infect Dis 190: 1697-1705.
    • (2004) J Infect Dis , vol.190 , pp. 1697-1705
    • Abel, K.1    Rourke, T.2    Lu, D.3    Bost, K.4    McChesney, M.B.5    Miller, C.J.6
  • 36
    • 84155189092 scopus 로고    scopus 로고
    • Use of hormonal contraceptives and risk of HIV-1 transmission: a prospective cohort study
    • Heffron R, Donnell D, Rees H, Celum C, Mugo N, et al. (2012) Use of hormonal contraceptives and risk of HIV-1 transmission: a prospective cohort study. Lancet Infect Dis 12: 19-26.
    • (2012) Lancet Infect Dis , vol.12 , pp. 19-26
    • Heffron, R.1    Donnell, D.2    Rees, H.3    Celum, C.4    Mugo, N.5
  • 37
    • 0032723177 scopus 로고    scopus 로고
    • The effect of one injection of Depo-Provera on the human vaginal epithelium and cervical ectopy
    • Mauck CK, Callahan MM, Baker J, Arbogast K, Veazey R,et al. (1999) The effect of one injection of Depo-Provera on the human vaginal epithelium and cervical ectopy. Contraception 60: 15-24.
    • (1999) Contraception , vol.60 , pp. 15-24
    • Mauck, C.K.1    Callahan, M.M.2    Baker, J.3    Arbogast, K.4    Veazey, R.5
  • 38
    • 20244368227 scopus 로고    scopus 로고
    • Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, in Rakai, Uganda
    • Wawer MJ, Gray RH, Sewankambo NK, Serwadda D, Li X, et al. (2005) Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, in Rakai, Uganda. J Infect Dis 191: 1403-1409.
    • (2005) J Infect Dis , vol.191 , pp. 1403-1409
    • Wawer, M.J.1    Gray, R.H.2    Sewankambo, N.K.3    Serwadda, D.4    Li, X.5
  • 39
    • 84155171087 scopus 로고    scopus 로고
    • Tenofovir-based pre-exposure prophylaxis for HIV prevention: evolving evidence
    • Celum C, Baeten JM, (2012) Tenofovir-based pre-exposure prophylaxis for HIV prevention: evolving evidence. Curr Opin Infect Dis 25: 51-57.
    • (2012) Curr Opin Infect Dis , vol.25 , pp. 51-57
    • Celum, C.1    Baeten, J.M.2
  • 40
    • 84865779923 scopus 로고    scopus 로고
    • Safety and Adherence to Intermittent Pre-Exposure Prophylaxis (PrEP) for HIV-1 in African Men Who Have Sex with Men and Female Sex Workers
    • Mutua G, Sanders E, Mugo P, Anzala O, Haberer JE, et al. (2012) Safety and Adherence to Intermittent Pre-Exposure Prophylaxis (PrEP) for HIV-1 in African Men Who Have Sex with Men and Female Sex Workers. PLoS One 7: e33103.
    • (2012) PLoS One , vol.7
    • Mutua, G.1    Sanders, E.2    Mugo, P.3    Anzala, O.4    Haberer, J.E.5


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