Incidence of HIV-related anal cancer remains increased despite long-term combined antiretroviral treatment: Results from the french hospital database on HIV

Journal of Clinical Oncology

Volumn 30, Issue 35, 2012, Pages 4360-4366

  Piketty, Christophe ^a   Selinger Leneman, Hana ^b   Bouvier, Anne Marie ^g,h   Belot, Aurelien ^h,i,j   Mary Krause, Murielle ^a   Duvivier, Claudine ^c   Bonmarchand, Manuela ^d   Abramowitz, Laurent ^e   Costagliola, Dominique ^b,d   Grabar, Sophie ^b,f  

^a HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^b INSERM   (France)

^c ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^d PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^e BICHAT HOSPITAL   (France)

^f Groupe Hospitalier Cochin Hôtel Dieu ^*  (France)

^g Institut Médical de Génétique et d Immunologie   (France)

^h Network of French Cancer Registries (FRANCIM)   (France)

ⁱ HOSPICES CIVILS DE LYON   (France)

^j INSTITUT DE VEILLE SANITAIRE   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

ADULT; ANUS CARCINOMA; ANUS SQUAMOUS CELL CARCINOMA; ARTICLE; CANCER INCIDENCE; CANCER REGISTRY; CANCER RISK; CD4 LYMPHOCYTE COUNT; FEMALE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HISTOPATHOLOGY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; MALE HOMOSEXUAL; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA;

ADULT; ANTI-HIV AGENTS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; ANUS NEOPLASMS; CARCINOMA, SQUAMOUS CELL; FEMALE; FRANCE; HIV INFECTIONS; HUMANS; INCIDENCE; MALE; MIDDLE AGED;

EID: 84870746261     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2012.44.5486     Document Type: Article

References (38)

1. Goedert JJ: The epidemiology of acquired immunodeficiency syndrome malignancies. Semin Oncol 27:390-401, 2000
2. Goedert JJ, Coté TR, Virgo P, et al: Spectrum of AIDS-associated malignant disorders. Lancet 351:1833-1839, 1998 (Pubitemid 28279706)
3. Frisch M, Biggar RJ, Goedert JJ: Human papillomavirus-associated cancers in patients with human immunodeficiency virus infection and acquired immunodeficiency syndrome. J Natl Cancer Inst 92:1500-1510, 2000
4. Piketty C, Selinger-Leneman H, Grabar S, et al: Marked increase in the incidence of invasive anal cancer among HIV-infected patients despite treatment with combination antiretroviral therapy. AIDS 22:1203-1211, 2008
5. Hessol NA, Holly EA, Efird JT, et al: Anal intraepithelial neoplasia in a multisite study of HIV-infected and high-risk HIV-uninfected women. AIDS 23:59-70, 2009
6. Palefsky JM, Holly EA, Efird JT, et al: Anal intraepithelial neoplasia in the highly active antiretroviral therapy era among HIV-positive men who have sex with men. AIDS 19:1407-1414, 2005 (Pubitemid 41800677)
7. Piketty C, Si-Mohamed A, Lanoy E, et al: Lack of regression of anal squamous intraepithelial lesions and anal HPV infection despite immune restoration under cART. 18th International AIDS Conference, Vienna, Austria, July 18-23, 2010
8. Wilkin TJ, Palmer S, Brudney KF, et al: Anal intraepithelial neoplasia in heterosexual and homosexual HIV-positive men with access to antiretroviral therapy. J Infect Dis 190:1685-1691, 2004 (Pubitemid 39411020)
9. de Pokomandy A, Rouleau D, Ghattas G, et al: HAART and progression to high-grade anal intraepithelial neoplasia in men who have sex with men and are infected with HIV. Clin Infect Dis 52:1174-1181, 2011
10. Diamond C, Taylor TH, Aboumrad T, et al: Increased incidence of squamous cell anal cancer among men with AIDS in the era of highly active antiretroviral therapy. Sex Transm Dis 32:314-320, 2005 (Pubitemid 40578072)
11. Bower M, Powles T, Newsom-Davis T, et al: HIV-associated anal cancer: Has highly active antiretroviral therapy reduced the incidence or improved the outcome? J Acquir Immune Defic Syndr 37:1563-1565, 2004 (Pubitemid 39658192)
12. Clifford GM, Polesel J, Rickenbach M, et al: Cancer risk in the Swiss HIV Cohort Study: Associations with immunodeficiency, smoking, and highly active antiretroviral therapy. J Natl Cancer Inst 97:425-432, 2005 (Pubitemid 40528605)
13. Engels EA, Pfeiffer RM, Goedert JJ, et al: Trends in cancer risk among people with AIDS in the United States 1980-2002. AIDS 20:1645-1654, 2006 (Pubitemid 44162407)
14. Shiels MS, Pfeiffer RM, Engels EA: Age at cancer diagnosis among persons with AIDS in the United States. Ann Intern Med 153:452-460, 2010
15. Franceschi S, Lise M, Clifford GM, et al: Changing patterns of cancer incidence in the early- and late-HAART periods: The Swiss HIV Cohort Study. Br J Cancer 103:416-422, 2010
16. Crum-Cianflone NF, Hullsiek KH, Marconi VC, et al: Anal cancers among HIV-infected persons: HAART is not slowing rising incidence. AIDS 24:535-543, 2010
17. Patel S, Chiplunkar S: Host immune responses to cervical cancer. Curr Opin Obstet Gynecol 21:54-59, 2009
18. Engels EA, Biggar RJ, Hall HI, et al: Cancer risk in people infected with human immunodeficiency virus in the United States. Int J Cancer 123:187-194, 2008 (Pubitemid 351705208)
19. Powles T, Robinson D, Stebbing J, et al: Highly active antiretroviral therapy and the incidence of non-AIDS-defining cancers in people with HIV infection. J Clin Oncol 27:884-890, 2009
20. Grulich AE, van Leeuwen MT, Falster MO, et al: Incidence of cancers in people with HIV/AIDS compared with immunosuppressed transplant recipients: A meta-analysis. Lancet 370:59-67, 2007 (Pubitemid 47017468)
21. Patel P, Hanson DL, Sullivan PS, et al: Incidence of types of cancer among HIV-infected persons compared with the general population in the United States, 1992-2003. Ann Intern Med 148:728-736, 2008 (Pubitemid 351717418)
22. Seaberg EC, Wiley D, Martínez-Maza O, et al: Cancer incidence in the multicenter AIDS Cohort Study before and during the HAART era: 1984 to 2007. Cancer 116:5507-5516, 2010
23. Silverberg MJ, Lau B, Justice AC, et al: Risk of anal cancer in HIV-infected and HIV-uninfected individuals in North America. Clin Infect Dis 54:1026-1034, 2012
24. Martin J, Volberding P: HIV and premature aging: A field still in its infancy. Ann Intern Med 153:477-479, 2010
25. Grabar S, Le Moing V, Goujard C, et al: Clinical outcome of patients with HIV-1 infection according to immunologic and virologic response after 6 months of highly active antiretroviral therapy. Ann Intern Med 133:401-410, 2000
26. Breslow NE, Day NE: Statistical Methods in Cancer Research, Vol II: The Design and Analysis of Cohort Studies. Lyon, France, IARC Scientific Publications No. 82, 1987
27. Lanoy E, Spano JP, Bonnet F, et al: The spectrum of malignancies in HIV-infected patients in 2006 in France: The ONCOVIH study. Int J Cancer 129:467-475, 2011
28. Silverberg MJ, Chao C, Leyden WA, et al: HIV infection and the risk of cancers with and without a known infectious cause. AIDS 23:2337-2345, 2009
29. Chaturvedi AK, Mbulaiteye SM, Engels EA: Underestimation of relative risks by standardized incidence ratios for AIDS-related cancers. Ann Epidemiol 18:230-234, 2008
30. Shiels MS, Goedert JJ, Engels EA: Recent trends and future directions in human immunodeficiency virus-associated cancer. Cancer 116:5344-5347, 2010
31. Guiguet M, Boué F, Cadranel J, et al: Effect of immunodeficiency, HIV viral load, and antiretroviral therapy on the risk of individual malignancies (FHDH-ANRS CO4): A prospective cohort study. Lancet Oncol 10:1152-1159, 2009
32. Reekie J, Kosa C, Engsig F, et al: Relationship between current level of immunodeficiency and non-acquired immunodeficiency syndrome-defining malignancies. Cancer 116:5306-5315, 2010
33. Silverberg MJ, Chao C, Leyden WA, et al: HIV infection, immunodeficiency, viral replication, and the risk of cancer. Cancer Epidemiol Biomarkers Prev 20:2551-2559, 2011
34. Thompson MA, Aberg JA, Cahn P, et al: Antiretroviral treatment of adult HIV infection: 2010 recommendations of the International AIDS Society-USA panel. JAMA 304:321-333, 2010
35. Kreuter A, Potthoff A, Brockmeyer NH, et al: Anal carcinoma in human immunodeficiency virus-positive men: Results of a prospective study from Germany. Br J Dermatol 162:1269-1277, 2010
36. Autran B, Carcelain G, Li TS, et al: Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease. Science 277:112-116, 1997 (Pubitemid 27450659)
37. Havlir DV, Schrier RD, Torriani FJ, et al: Effect of potent antiretroviral therapy on immune responses to Mycobacterium avium in human immunodeficiency virus-infected subjects. J Infect Dis 182:1658-1663, 2000
38. Komanduri KV, Viswanathan MN, Wieder ED, et al: Restoration of cytomegalovirus-specific CD4+ T-lymphocyte responses after ganciclovir and highly active antiretroviral therapy in individuals infected with HIV-1. Nat Med 4:953-956, 1998 (Pubitemid 28364037)