Ultrasound sensitivity for thyroid malignancy is increased by real-time elastography: A prospective multicenter study

Journal of Clinical Endocrinology and Metabolism

Volumn 97, Issue 12, 2012, Pages 4524-4530

  Trimboli, Pierpaolo ^a   Guglielmi, Rinaldo ^b   Monti, Salvatore ^c   Misischi, Irene ^b   Graziano, Filomena ^b   Nasrollah, Naim ^a   Amendola, Stefano ^a   Morgante, Sara Nazzarena ^c   Deiana, Maria Grazia ^c   Valabrega, Stefano ^c   Toscano, Vincenzo ^c   Papini, Enrico ^b  

^a Piazza San Bartolomeo All'Isola 21   (Italy)

^b REGINA APOSTOLORUM HOSPITAL   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; B SCAN; CLINICAL TRIAL; COLOR ULTRASOUND FLOWMETRY; DIAGNOSTIC ACCURACY; ELASTOGRAPHY; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NEEDLE BIOPSY; PREDICTIVE VALUE; PRIORITY JOURNAL; PROSPECTIVE STUDY; REAL TIME ELASTOGRAPHY; SENSITIVITY AND SPECIFICITY; THYROID CANCER; THYROID NODULE;

ADULT; AGED; CARCINOMA; COMPUTER SYSTEMS; DIAGNOSIS, DIFFERENTIAL; ELASTICITY IMAGING TECHNIQUES; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; SENSITIVITY AND SPECIFICITY; THYROID NEOPLASMS; THYROID NODULE;

EID: 84870744710     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2012-2951     Document Type: Article

References (30)

1. Hegedüs L 2004 Thyroid Nodule. N Engl J Med 351:1764-1771
2. Vander JB, Gaston EA, Dawber TR 1968 The significance of nontoxic thyroid nodules: final report of a 15-year study of the incidence of thyroid malignancy. Ann Intern Med 69:537-540
3. Ezzat S, Sarti DA, Cain DR, Braunstein GD 1994 Thyroid incidentalomas. Prevalence by palpation and ultrasonography. Arch Intern Med 154:1838-1840 (Pubitemid 24262001)
4. Gharib H, Papini E 2007 Thyroid nodules: clinical importance, assessment and treatment. Endocrinol Metab Clin North Am 36:707-735, vi (Pubitemid 47135591)
5. Gharib H, Papini E, Paschke R, Duick DS, Valcavi R, Hegedüs L, Vitti P; AACE/AME/ETA Task Force on Thyroid Nodules 2010 AACE/AME/ETA Task Force on Thyroid Nodules. American Association of Clinical Endocrinologists, Associazione Medici Endocrinologi, and European Thyroid Association medical guidelines for clinical practice for the diagnosis and management of thyroid nodules. J Endocrinol Invest 33:1-50
6. Cooper DS, Doherty GM, Haugen BR, Kloos RT, Lee SL, Mandel SJ, Mazzaferri EL, McIver B, Sherman SI, Tuttle RM; American Thyroid Association Guidelines Taskforce 2006 The American Thyroid Association Guidelines Taskforce. Management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid 16:109-142
7. Solbiati L, Osti V, Cova L, Tonolini M 2001 Ultrasound of thyroid, parathyroid glands and neck lymph nodes. Eur Radiol 11:2411-2424 (Pubitemid 33114892)
8. Kim EK, Park CS, Chung WY, Oh KK, Kim DI, Lee JT, Yoo HS 2002 New sonographic criteria for recommending fine-needle aspiration biopsy of nonpalpable solid nodules of the thyroid. Am J Roentgenol 178:687-691
9. Rago T, Vitti P, Chiovato L, Mazzeo S, De Liperi A, Miccoli P, Viacava P, Bogazzi F, Martino E, Pinchera A 1998 Role of conventional ultrasonography and color flow-doppler sonography in predicting malignancy in 'cold' thyroid nodules. Eur J Endocrinol 138:41-46 (Pubitemid 28078807)
10. Frates MC, Benson CB, Charboneau JW, Cibas ES, Clark OH, Coleman BG, Cronan JJ, Doubilet PM, Evans DB, Goellner JR, Hay ID, Hertzberg BS, Intenzo CM, Jeffrey RB, Langer JE, Larsen PR, Mandel SJ, Middleton WD, Reading CC, Sherman SI, Tessler FN; Society of Radiologists in Ultrasound 2005 Management of thyroid nodules detected at US: Society of Radiologists in Ultrasound consensus conference statement. Radiology 237:794-800
11. Mandel SJ 2004 Diagnostic use of ultrasonography in patients with nodular thyroid disease. Endocr Pract 10:246-252
12. Cochand-Priollet B, Guillausseau PJ, Chagnon S, Hoang C, Guillausseau-Scholer C, Chanson P, Dahan H, Warnet A, Tran Ba Huy PT, Valleur P 1994 The diagnostic value of fine-needle aspiration biopsy under ultrasonography in nonfunctional thyroid nodules: a prospective study comparing cytologic and histologic findings. Am J Med 97:152-157 (Pubitemid 24250675)
13. Lyshchik A, Higashi T, Asato R, Tanaka S, Ito J, Mai JJ, Pellot- Barakat C, Insana MF, Brill AB, Saga T, Hiraoka M, Togashi K 2005 Thyroid gland tumor diagnosis at US elastography. Radiology 237:202-211
14. Rago T, Santini F, Scutari M, Pinchera A, Vitti P 2007 Elastography: new developments in ultrasound for predicting malignancy in thyroid nodules. J Clin Endocrinol Metab 92:2917-2922 (Pubitemid 47236350)
15. Asteria C, Giovanardi A, Pizzocaro A, Cozzaglio L, Morabito A, Somalvico F, Zoppo A 2008 US-elastography in the differential diagnosis of benign and malignant thyroid nodules. Thyroid 18:523-531 (Pubitemid 351667834)
16. Tranquart F, Bleuzen A, Pierre-Renoult P, Chabrolle C, Sam Giao M, Lecomte P 2008 Elastosonography of thyroid lesions. J Radiol 89:35-39 (Pubitemid 351312048)
17. Dighe M, Bae U, Richardson ML, Dubinsky TJ, Minoshima S, Kim Y 2008 Differential diagnosis of thyroid nodules with US elastography using carotid artery pulsation. Radiology 248:662-669
18. Rubaltelli L, Corradin S, Dorigo A, Stabilito M, Tregnaghi A, Borsato S, Stramare R 2009 Differential diagnosis of benign and malignant thyroid nodules at elastosonography. Ultraschall Med 30:175-179
19. Hong Y, Liu X, Li Z, Zhang X, Chen M, Luo Z 2009 Real-time ultrasound elastography in the differential diagnosis of benign and malignant thyroid nodules. J Ultrasound Med 28:861-867
20. Friedrich-Rust M, Sperber A, Holzer K, Diener J, Grünwald F, Badenhoop K, Weber S, Kriener S, Herrmann E, Bechstein WO, Zeuzem S, Bojunga J 2010 Real-time elastography and contrastenhanced ultrasound for the assessment of thyroid nodules. Exp Clin Endocrinol Diabetes 118:602-609
21. Kagoya R, Monobe H, Tojima H 2010 Utility of elastography for differential diagnosis of benign and malignant thyroid nodules. Otolaryngol Head Neck Surg 143:230-234
22. Unlütürk U, Erdogan MF, Demir O, Güllü S, Başkal N 9 August 2012 Ultrasound-Elastography is not superior to gray-scale ultrasound in predicting malignancy in thyroid nodules. Thyroid 10.1089/thy.2011-0502
23. Royal College of Physicians of London 2007 Guidelines for the management of thyroid cancer. 2nd ed. Suffolk, UK: The Lavenham Press
24. Galen RS, Gambino SL 1975 How to determine the predictive value and efficiency of a test when reading a scientific paper. In: Beyond normality: the predictive value and efficiency of medical diagnosis. New York: John Wiley; 29-40
25. Wienke JR, Chong WK, Fielding JR, Zou KH, Mittelstaedt CA 2003 Sonographic features of benign thyroid nodules: interobserver reliability and overlap with malignancy. J Ultrasound Med 22:1027-1031 (Pubitemid 37210945)
26. Papini E, Guglielmi R, Bianchini A, Crescenzi A, Taccogna S, Nardi F, Panunzi C, Rinaldi R, Toscano V, Pacella CM 2002 Risk of malignancy in nonpalpable thyroid nodules: predictive value of ultrasound and color-Doppler features. J Clin Endocrinol Metab 87:1941-1946 (Pubitemid 34521470)
27. Lee YH, Kim DW, In HS, Park JS, Kim SH, Eom JW, Kim B, Lee EJ, Rho MH 2011 Differentiation between benign and malignant solid thyroid nodules using an US classification system. Korean J Radiol 12:559-567
28. Bojunga J, Herrmann E, Meyer G, Weber S, Zeuzem S, Friedrich-Rust M 2010 Real-time elastography for the differentiation of benign and malignant thyroid nodules: a meta-analysis. Thyroid 20:1145-1150
29. Park SH, Kim SJ, Kim EK, Kim MJ, Son EJ, Kwak JY 2009 Interobserver agreement in assessing the sonographic and elastographic features of malignant thyroid nodules. AJR Am J Roentgenol 193:W416-W423
30. Hegedu̧s L 2010 Can elastography stretch our understanding of thyroid histomorphology? J Clin Endocrinol Metab 95:5213-5215