Uterine lavage or aspirate: Which view of the intrauterine environment?

Reproductive Sciences

Volumn 19, Issue 10, 2012, Pages 1125-1132

  Hannan, N J ^a,b   Nie, G ^a   Rainzcuk, A ^a   Rombauts, L J F ^a,c   Salamonsen, L A ^a  

^a HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c MONASH UNIVERSITY   (Australia)

Author keywords

aspirate; cytokine multiplex; proprotein convertase 6; SELDI TOF MS; uterine lavage

Indexed keywords

PROPROTEIN CONVERTASE 6; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; ASPIRATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GLYCOCALYX; HUMAN; HUMAN CELL; LAVAGE; PRIORITY JOURNAL; SURFACE ENHANCED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; UTERUS; UTERUS CAVITY; UTERUS FLUID;

ADULT; ANALYTIC SAMPLE PREPARATION METHODS; FEMALE; HUMANS; PROTEIN ARRAY ANALYSIS; PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; THERAPEUTIC IRRIGATION; UTERINE DISEASES; UTERUS; VACUUM CURETTAGE;

EID: 84870735862     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719112443879     Document Type: Article

References (27)

1. Boomsma CM, Kavelaars A, Eijkemans MJ, et al. Cytokine profiling in endometrial secretions: a non-invasive window on endometrial receptivity. Reprod Biomed Online. 2009 ; 18 (1). 85-94
2. Boomsma CM, Kavelaars A, Eijkemans MJ, et al. Endometrial secretion analysis identifies a cytokine profile predictive of pregnancy in IVF. Hum Reprod. 2009 ; 24 (6). 1427-1435
3. Casado-Vela J, Rodriguez-Suarez E, Iloro I, et al. Comprehensive proteomic analysis of human endometrial fluid aspirate. J Proteome Res. 2009 ; 8 (10). 4622-4632
4. Hannan NJ, Stephens AN, Rainczuk A, Hincks C, Rombauts LJ. Salamonsen LA. 2D-DiGE analysis of the human endometrial secretome reveals differences between receptive and nonreceptive states in fertile and infertile women. J Proteome Res. 2010 ; 9 (12). 6256-6264
5. Lopata A, Agresta F, Quinn MA, Smith C, Ostor AG, Salamonsen LA. Detection of endometrial cancer by determination of matrix metalloproteinases in the uterine cavity. Gynecol Oncol. 2003 ; 90 (2). 318-324
6. Scotchie JG, Fritz MA, Mocanu M, Lessey BA, Young SL. Proteomic analysis of the luteal endometrial secretome. Reprod Sci. 2009 ; 16 (9). 883-893
7. van der Gaast MH, Beier-Hellwig K, Fauser BC, Beier HM, Macklon NS. Endometrial secretion aspiration prior to embryo transfer does not reduce implantation rates. Reprod Biomed Online. 2003 ; 7 (1). 105-109
8. van der Gaast MH, Macklon NS, Beier-Hellwig K, et al. The feasibility of a less invasive method to assess endometrial maturation-comparison of simultaneously obtained uterine secretion and tissue biopsy. BJOG. 2009 ; 116 (2). 304-312
9. Simon C, Mercader A, Frances A, et al. Hormonal regulation of serum and endometrial IL-1 alpha, IL-1 beta and IL-1ra: IL-1 endometrial microenvironment of the human embryo at the apposition phase under physiological and supraphysiological steroid level conditions. J Reprod Immunol. 1996 ; 31 (3). 165-184
10. Jones CJ, Aplin JD. Glycosylation at the fetomaternal interface: does the glycocode play a critical role in implantation?. Glycoconj J. 2009 ; 26 (3). 359-366
11. Germeyer A, Klinkert MS, Huppertz AG, et al. Expression of syndecans, cell-cell interaction regulating heparan sulfate proteoglycans, within the human endometrium and their regulation throughout the menstrual cycle. Fertil Steril. 2007 ; 87 (3). 657-663
12. Hannan NJ, Stoikos CJ, Stephens AN, Salamonsen LA. Depletion of high-abundance serum proteins from human uterine lavages enhances detection of lower-abundance proteins. J Proteome Res. 2009 ; 8 (2). 1099-1103
13. Hannan N, Paiva P, Meehan K, Rombauts LJ, Gardner D, Salamonsen L. Analysis of fertility-related soluble mediators in human uterine fluid identifies VEGF as a key regulator of embryo implantation. Endocrinology. 2011 ; 152 (12). 4948-4956
14. Paiva P, Hannan NJ, Hincks C, et al. Human chorionic gonadotrophin regulates FGF2 and other cytokines produced by human endometrial epithelial cells, providing a mechanism for enhancing endometrial receptivity. Hum Reprod. 2011 ; 26 (5). 1153-1162
15. Fugere M, Appel J, Houghten RA, Lindberg I, Day R. Short polybasic peptide sequences are potent inhibitors of PC5/6 and PC7: use of positional scanning-synthetic peptide combinatorial libraries as a tool for the optimization of inhibitory sequences. Mol Pharmacol. 2007 ; 71 (1). 323-332
16. Heng S, Hannan NJ, Rombauts LJ, Salamonsen LA, Nie G. PC6 levels in uterine lavage are closely associated with uterine receptivity and significantly lower in a subgroup of women with unexplained infertility. Hum Reprod. 2011 ; 26 (4). 840-846
17. Casu B, Naggi A, Torri G. Heparin-derived heparan sulfate mimics to modulate heparan sulfate-protein interaction in inflammation and cancer. Matrix Biol. 2010 ; 29 (6). 442-452
18. Aplin JD, Hey NA, Li TC. MUC1 as a cell surface and secretory component of endometrial epithelium: reduced levels in recurrent miscarriage. Am J Reprod Immunol. 1996 ; 35 (3). 261-266
19. Aoki D, Kawakami H, Nozawa S, Udagawa Y, Iizuka R, Hirano H. Differences in lectin binding patterns of normal human endometrium between proliferative and secretory phases. Histochemistry. 1989 ; 92 (3). 177-184
20. Jones CJ, Aplin JD, Burton GJ. First trimester histiotrophe shows altered sialylation compared with secretory phase glycoconjugates in human endometrium. Placenta. 2010 ; 31 (7). 576-580
21. Thathiah A, Brayman M, Dharmaraj N, Julian JJ, Lagow EL, Carson DD. Tumor necrosis factor alpha stimulates MUC1 synthesis and ectodomain release in a human uterine epithelial cell line. Endocrinology. 2004 ; 145 (9). 4192-4203
22. Thathiah A, Carson DD. MT1-MMP mediates MUC1 shedding independent of TACE/ADAM17. Biochem J. 2004 ; 382 (pt 1). 363-373
23. MacLaughlin DT, Richardson GS. Analysis of human uterine luminal fluid proteins following radiolabeling by reductive methylation: comparison of proliferative and secretory phase samples. Biol Reprod. 1983 ; 29 (3). 733-742
24. Sylvan PE, Maclaughlin DT, Richardson GS, Scully RE, Nikrui N. Human uterine luminal fluid proteins associated with secretory phase endometrium: progesterone-induced products?. Biol Reprod. 1981 ; 24 (2). 423-429
25. Voss HJ, Beato M. Human uterine fluid proteins: gel electrophoretic pattern and progesterone-binding properties. Fertil Steril. 1977 ; 28 (9). 972-980
26. Jones RL, Hannan NJ, Kaitu'u TJ, Zhang J, Salamonsen LA. Identification of chemokines important for leukocyte recruitment to the human endometrium at the times of embryo implantation and menstruation. J Clin Endocrinol Metab. 2004 ; 89 (12). 6155-6167
27. Hannan NJ, Jones RL, Critchley HO, et al. Coexpression of fractalkine and its receptor in normal human endometrium and in endometrium from users of progestin-only contraception supports a role for fractalkine in leukocyte recruitment and endometrial remodeling. J Clin Endocrinol Metab. 2004 ; 89 (12). 6119-6129