Salt chamber treatment is ineffective in treating eosinophilic inflammation in asthma

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 68, Issue 1, 2013, Pages 125-127

  Sandell, J ^a   Hedman, J ^b   Saarinen, K ^a   Haahtela, T ^c  

^a Etela karjalan Allergia ja Ymparistoinstituutti   (Finland)

^b CENTRAL FINLAND CENTRAL HOSPITAL   (Finland)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

asthma; eosinophils; halotherapy; sputum

Indexed keywords

CORTICOSTEROID; EOSINOPHIL CATIONIC PROTEIN; SODIUM CHLORIDE;

ADULT; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG MEGADOSE; EOSINOPHILIA; EOSINOPHILIC INFLAMMATION; FEMALE; HUMAN; INFLAMMATION; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SALT CHAMBER TREATMENT; SPELEOTHERAPY; SPUTUM LEVEL; THERAPY EFFECT; TREATMENT OUTCOME;

ADMINISTRATION, INHALATION; ADRENAL CORTEX HORMONES; ADULT; AGED; ANTI-ASTHMATIC AGENTS; ASTHMA; DRUG THERAPY, COMBINATION; EOSINOPHILS; FEMALE; HUMANS; MALE; MIDDLE AGED; SODIUM CHLORIDE;

EID: 84870605641     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/all.12061     Document Type: Article

References (10)

1. Crimi E, Spanevello A, Neri M, Ind PW, Rossi GA, Brusasco V,. Dissociation between airway inflammation and airway hyperresponsiveness in allergic asthma. Am J Crit Care Med 1998; 157: 4-9.
2. Kauppinen RS, Vilkka V, Hedman J, Sintonen H,. Ten-year follow-up of early intensive self-management guidance in newly diagnosed patients with asthma. J Asthma 2011; 48: 945-951.
3. Venge P,. Monitoring the allergic inflammation. Allergy 2004; 59: 26-32.
4. Pizzichini E, Pizzichini MM, Efthimiadis A, Dolovich J, Hargreave FE,. Measuring airway inflammation in asthma: eosinophils and eosinophilic cationic protein in induced sputum compared with peripheral blood. J Allergy Clin Immunol 1997; 99: 539-544.
5. Hedman J, Hugg T, Sandell J, Haahtela T,. The effect of salt chamber treatment on bronchial hyperresponsiveness in asthmatics. Allergy 2006; 61: 605-610.
6. Djukanovic R, Sterk PJ, Fahy JV, Hargreave FE,. Standardised methodology of sputum induction and processing. Eur Respir J Suppl 2002; 37: 1s-2s.
7. Anderson SD, Spring J, Moore B, Rodwell LT, Spalding N, Gonda I, et al. The effect of inhaling a dry powder of sodium chloride on the airways of asthmatic subjects. Eur Respir J 1997; 10: 2465-2473.
8. Metso T, Rytilä P, Peterson C, Haahtela T,. Granulocyte markers in induced sputum in patients with respiratory disorders and healthy persons obtained by two sputum-processing methods. Respir Med 2001; 95: 48-55.
9. Zuyderduyn S, Sukkar MB, Fust A, Dhaliwal S, Burgess JK,. Treating asthma means treating airway smooth muscle cells. Eur Respir J 2008; 32: 265-274.
10. Downie SR, Salome CM, Verbanck S, Thompson B, Berend N, King GG,. Ventilation heterogeneity is a major determinant of airway hyperresponsiveness in asthma, independent of airway inflammation. Thorax 2007; 62: 684-689.