Histopathologic effects of Echinacea purpurea extract on sodium arsenite-induced hepatic disorders

Comparative Clinical Pathology

Volumn 21, Issue 6, 2012, Pages 1629-1632

  Heidari, Marzieh ^a   Rezaie, Annahita ^a   Broojeni, Mehdi Pourmahdi ^a   Najafzadeh, Hossein ^a   Mohammadian, Babak ^a  

^a SHAHID CHAMRAN UNIVERSITY OF AHVAZ   (Iran)

Author keywords

Arsenic; Echinacea purpurea; Hepatotoxicity; Pathology; Rat

Indexed keywords

EID: 84870603126     PISSN: 16185641     EISSN: 1618565X     Source Type: Journal    
DOI: 10.1007/s00580-011-1338-9     Document Type: Article

References (17)

1. Arteel GE, Guo L, Schlierf T, Beier JI, Kaiser JP, Chen TS, Liu M, Conklin DJ, Miller HL, Montfort CV, States JC (2008) Subhepatotoxic exposure to arsenic enhances lipopolysaccharide induced liver injury in mice. Toxicol Appl Pharmacol 226: 128-139.
2. Barcz E, Sommer E, Nartowska J, Balan BJ, Chorostowska-Wynimko J, Skopinska-Rozewska E (2007) Influence of Echinacea purpurea intake during pregnancy on fetal growth and tissue angiogenic activity. Folia Histochem 45: 35-39.
3. Bashir S, Sharma Y, Irshad M, Nag MTC, Tiwari M, Kabra M, Dogra TD (2006) Arsenic induced apoptosis in rat liver following repeated 60 days exposure. Toxicology 217(1): 63-70.
4. Cheng B, Hung CT, Chiu W (2002) Herbal medicine and anaesthesia. HKMJ 8(2): 123-130.
5. Cullen JM (2007) Liver, biliary system and exocrine pancreas. In: Mcgovin MD, Zachary JF (eds) Pathologic basis of veterinary disease. Elsevier, China, pp 393-455.
6. Datta S, Saha DR, Ghosh D, Majumdar T, Bhattacharya SH, Mazumder SH (2007) Sub-lethal concentration of arsenic interferes with the proliferation of hepatocytes and induces in vivo apoptosis in Clariasbatrachus L. Comp Biochem Physiol C Toxicol Pharmacol 145(3): 339-349.
7. Flora SJS (1999) Arsenic-induced oxidative stress and its reversibility following combined administration of n-acetylcysteine and meso 2, 3-dimercaptosuccinic acid in rats. Clin Exp Pharmacol 26: 865-869.
8. Ghosh D, Ghosh S, Sarkar S, Ghosh A, Das N, Saha KD, Mandal AK (2010) Quercetin in vesicular delivery systems: evaluation in combating arsenic induced acute liver toxicity associated gene expression in rat model. Chem Biol Interact 186: 61-71.
9. Khaksary-Mahabady M, Ranjbar R, Arzi A, Papahn AA, Najafzadeh H (2006) A comparison study of effect of Echinacea extract and levamisole on phenytoin-induced cleft palate in mice. Regul Toxicol Pharmacol 46: 163-166.
10. Manna P, Sinha M, Sil PC (2007) Protection of arsenic-induced hepatic disorder by arjunolic acid. Basic Clin Pharmacol Toxicol 101(5): 333-338.
11. Miller SC (2005) Echinacea: a miracle herb against aging and cancer? Evidence in vivo in mice. Evidence-Based Complement Altern Med 2: 309-314.
12. Nair SB, Jhala DD, Chinoy NJ (2004) Beneficial effects of certain antidotes in mitigating fluoride and/or arsenic induced hepatotoxicity in mice. Fluoride 37: 60-70.
13. Nanji AA, Khettry U, Sadrzadeh SM (1994) Lactobacillus feeding reduces endotoxemia and severity of experimental alcoholic liver disease. Proc Soc Exp Biol Med 205: 243-247.
14. Ramanathan K, Shila S, Kumaran S, Panneerselvam C (2003) Ascorbic acid and α-tocopherol as potent modulators on arsenic induced toxicity in mitochondria. J Nutr Biochem 14: 416-420.
15. Ratnaike RN (2003) Acute and chronic arsenic toxicity. Postgrad Med 79: 391-396.
16. Santra A, Chowdhury A, Ghatak S, Biswas A, Dhali GK (2007) Arsenic induces apoptosis in mouse liver is mitochondria dependent and is abrogated by N-acetylcysteine. Toxicol Appl Pharmacol 220(2): 146-155.
17. Skaudickas D, Kondrotas A, Baltrusaitis K (2004) The effect of Echinacea purpurea extract on sexual glands of male rats. Medicina 40: 1211-1218.