Nitroglycerin: A review of its use in the treatment of vascular occlusion after soft tissue augmentation

Dermatologic Surgery

Volumn 38, Issue 12, 2012, Pages 1889-1897

  Kleydman, Kate ^a   Cohen, Joel L ^b   Marmur, Ellen ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b About Skin Dermatology and DermSurgery   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FILLER; GLYCERYL TRINITRATE; NITRO TD PATCH A; UNCLASSIFIED DRUG;

ALGORITHM; APPLICATION SITE IRRITATION; BLOOD VESSEL OCCLUSION; DISTRIBUTION VOLUME; DRUG FORMULATION; DRUG HALF LIFE; DRUG MECHANISM; EDEMA; ERYTHEMA; ESTHETIC SURGERY; HUMAN; ISCHEMIA; LASER DOPPLER FLOWMETRY; MEDICAL LITERATURE; NONHUMAN; NOSE NECROSIS; NOSE RECONSTRUCTION; PAPULE; PASTE; PRIORITY JOURNAL; REVIEW; TREATMENT INDICATION; VASODILATATION;

ADMINISTRATION, TOPICAL; COSMETIC TECHNIQUES; DOSAGE FORMS; HUMANS; ISCHEMIA; NECROSIS; NITROGLYCERIN; SKIN; VASODILATOR AGENTS;

EID: 84870564449     PISSN: 10760512     EISSN: 15244725     Source Type: Journal    
DOI: 10.1111/dsu.12001     Document Type: Review

References (33)

1. The internet drug index. Available from: http://rxlist.com/transder- nitro-drug.htm Accessed March 5, 2011.
2. The American Society for Dermatologic Surgery Releases New Procedure Survey Data. Available from: http://www.asds.net/ TheAmericanSocietyforDermatologicSurgeryReleases NewProcedureSurveyData.aspx. Accessed April 9, 2012.
3. Bailey SH, Cohen JL, Kenkel JM,. Etiology, prevention and treatment of dermal filler complications. Aesthetic Surg J 2011; 31: 110-21.
4. Cohen JL,. Understanding, avoiding and managing dermal filler complications. Dermatol Surg 2008; 34: s92-9. (Pubitemid 351792857)
5. Cohen JL, Brown MR,. Anatomic considerations for soft tissue augmentation of the face. J Drugs Dermatol 2009; 8: 13-6.
6. Glaich D, Cohen J, Goldberg L,. Injection necrosis of the glabella: protocol for prevention and treatment after use of dermal fillers. Dermatol Surg 2006; 32: 276-81.
7. Grunebaum LD, Elsaie ML, Kaufman JY,. Six-month, double-blind, randomized, split-face study to compare the efficacy and safety of calcium hydroxylapatite (CaHA) mixed with lidocaine and CaHA alone for correction of nasolabial fold wrinkles. Dermatol Surg 2008; 36: 760-5.
8. Grunebaum LD, Allemann IB, Dayan S, Mandy S, Baumann L,. The risk of alar necrosis associated with dermal filler injection. Dermatol Surg 2009; 35: 1635-40.
9. Sanchz S, Schippert W, Ulmer A, Rassner G, Fierlbeck G,. Arterial embolization caused by injection of hyaluronic acid (Restylane). Br J Dermatol 2002; 146: 928-9. (Pubitemid 34539217)
10. Winslow C,. The management of dermal filler complications. Facial Plast Surg 2009; 25: 124-8.
11. Sclafani A, Fagien S,. Treatment of injectable soft tissue filler complications. Dermatol Surg 2009; 35: 1672-80.
12. Arteriole and red blood cells, SEM. [Available at sciencephoto.com]. Accessed March 10, 2011.
13. Schonberger BR, Worden WS, Shahmohammadi K, Menn K, Silverman TJ,. Topical non-iontophoretic application of acetylcholine and nitroglycerin via a translucent patch: a new means for assessing microvascular reactivity. Yale J Biol Med 2006; 79: 1-7.
14. Wikipedia. Available from: http://en.wikipedia.org/wiki/Glyceryl- trinitrate-(pharmacology Accessed March 7, 2011
15. Thomas PDR. Physicians' Desk Reference (63rd ed). Montvale, NJ: Thomas PDR; 2009: 205, 217, 299, 2966.
16. Imoto S, Kuramoto M, Iwabuch K, Nagal H, Shimpo K,. Percutaneous chronic toxicity study of 10% nitroglycerin (NT-1 ointment) in rabbits. J Toxicol Sci 1986; 11: 59-70. (Pubitemid 16091385)
17. Drug information online. Available from: http://www.drugs.com/mmx/nitro- bid.html Accessed March 5, 2011.
18. Hanke CW, Higley HR, Jolivette DM, Swanson NA, Stegman SJ,. Abscess formation and local necrosis after treatment with Zyderm or Zyplast collagen implant. J Am Acad Dermatol 1991; 25: 319-26.
19. Stegman SJ, Chu S, Armstrong RC,. Adverse reactions to bovine collagen implant: clinical and histologic features. J Dermatol Surg Oncol 1988; 14: 39-48.
20. Cohen J, Onwudiwe O,. Vascular compromise after hyaluronic acid cheek augmentation. J Drugs Dermatol 2012; 11 (3 Suppl): s1-3.
21. Bolognia J, Jorizzo J, Rapini R, eds. Dermatology (2nd ed). Maryland Heights, MO; Mosby, 2008.
22. Sykes JM,. Applied anatomy of the temporal region and forehead for injectable fillers. J Drugs Dermatol 2009; 10 (Suppl): s24-7.
23. Kang MS, Park ES, Shin HS, Kim Y, et al. Skin necrosis of the nasal ala after injection of dermal fillers. Dermatol Surg 2011; 37: 375-80.
24. Inoue K, Sato K, Matsumoto D, Gonda K, Yeshimura K,. Arterial embolization and skin necrosis of the nasal ala following injection of dermal fillers. Plast Reconstr Surg 2008; 121: 127-8.
25. Lambros V,. The use of hyaluronidase to reverse the effects of hyaluronic acid filler. Plast Reconstr Surg 2004; 114: 277. (Pubitemid 39195681)
26. Hirsch RJ, Cohen JL, Carruthers JD,. Successful management of an unusual presentation of impending necrosis following a hyaluronic acid injection embolus and a proposed algorithm for management with hyaluronidase. Dermatol Surg 2007; 33: 357-60. (Pubitemid 46328237)
27. Hirsch RJ, Lupo M, Cohen JL, Duffy D,. Delayed presentation of impending necrosis following soft tissue augmentation with hyaluronic acid and successful management with hyaluronidase. J Drugs Dermatol 2007; 6: 325-8.
28. Lee A, Grummer SE, Kriegel D, Marmur E,. Hyaluronidase. Dermatol Surg 2010; 36: 1071-7.
29. Cox SE,. Clinical experience with filler complications. Dermatol Surg 2009; 35 (Suppl 2): 1661-6.
30. Dinehart S, Henry L,. Dietary supplements: altered coagulation and effects of bruising. Dermatol Surg 2005; 31: s819-26.
31. Kim SG, Kim YJ, Lee CJ,. Salvage of nasal skin in a case of venous compromise after hyaluronic acid filler injection using prostaglandin E. Dermatol Surg 2011; 37: 1817-9.
32. Nichter LS, Morwood DT, Williams GS, Spence RJ,. Expanding the limits of composite grafting: a case report of successful nose replantation assisted by hyperbaric oxygen. Plast Reconstr Surg 1991; 87: 337-40.
33. Rapley JH, Lawrence WT, Witt PD,. Composite grafting and hyperbaric oxygen therapy in pediatric nasal tip reconstruction after avulsive dog bite injury. Ann Plast Surg 2001; 46: 434-8. (Pubitemid 32319685)