UVB immunosuppression: Vitamin D or not vitamin D? That is the question

Journal of Investigative Dermatology

Volumn 132, Issue 12, 2012, Pages 2676-2678

  Xu, Hui ^a   Elmets, Craig A ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VITAMIN D;

ALLERGIC ENCEPHALOMYELITIS; CELLULAR IMMUNITY; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; NONHUMAN; PHOTOTHERAPY; PRIORITY JOURNAL; PSORIASIS; REVIEW; ULTRAVIOLET B RADIATION;

EID: 84870561100     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2012.327     Document Type: Note

References (15)

1. Arnson Y, Amital H, Shoenfeld Y (2007) Vitamin D and autoimmunity: new aetiological and therapeutic considerations. Ann Rheum Dis 66:1137-42 (Pubitemid 47309727)
2. Becklund BR, Severson KS, Vang SV et al. (2010) UV radiation suppresses experimental autoimmune encephalomyelitis independent of vitamin D production. Proc Natl Acad Sci USA 107:6418-23
3. Bernard JJ, Cowing-Zitron C, Nakatsuji T et al. (2012) Ultraviolet radiation damages self noncoding RNA and is detected by TLR3. Nat Med 18:1286-90
4. Elmets CA, Bergstresser PR, Tigelaar RE et al. (1983) Analysis of mechanism of unresponsiveness produced by haptens painted on skin exposed to low dose ultraviolet radiation. J Exp Med 158:781-94 (Pubitemid 13051345)
5. Hart PH, Gorman S, Finlay-Jones JJ (2011) Modulation of the immune system by UV radiation: more than just the effects of vitamin D?. Nat Rev Immunol 11:584-96
6. Krutmann JT, Elmets CA (eds) (1995) Photoimmunology. Blackwell Scientific: Oxford
7. Palmer MT, Lee YK, Maynard CL et al. (2011) Lineage-specific effects of 1,25-dihydroxyvitamin D(3) on the development of effector CD4 T cells. J Biol Chem 286:997-1004
8. Ross AC, Manson JE, Abrams SA et al. (2011) The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab 96:53-8
9. Royal Iii W, Mia Y, Li H et al. (2009) Peripheral blood regulatory T cell measurements correlate with serum vitamin D levels in patients with multiple sclerosis. J Neuroimmunol 213:135-41
10. Schauber J, Gallo RL (2008) The vitamin D pathway: a new target for control of the skin's immune response?. Exp Dermatol 17:633-9 (Pubitemid 352044354)
11. Schwarz A, Navid F, Sparwasser T et al. (2012) 1,25-Dihydroxyvitamin D exerts similar immunosuppressive effects as UVR but is dispensable for local UVR-induced immunosuppression. J Invest Dermatol 132:2762-9
12. Schwarz A, Noordegraaf M, Maeda A et al. (2010) Langerhans cells are required for UVRinduced immunosuppression. J Invest Dermatol 130:1419-27
13. Schwarz T (2008) 25 years of UV-induced immunosuppression mediated by T cells; from disregarded T suppressor cells to highly respected regulatory T cells. Photochem Photobiol 84:10-8 (Pubitemid 350265098)
14. Sreevidya CS, Fukunaga A, Khaskhely NM et al. (2010) Agents that reverse UV-induced immune suppression and photocarcinogenesis affect DNA repair. J Invest Dermatol 130:1428-37
15. van der Aar AMG, Sibiryak DS, Bakdash G et al. (2011) Vitamin D3 targets epidermal and dermal dendritic cells for induction of distinct regulatory T cells. J Allergy Clin Immunol 127:1532-40. e7