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Volumn 14, Issue 5, 2012, Pages 441-448

Mucosal melanoma: Pathogenesis, clinical behavior, and management

Author keywords

Anorectal melanoma; C KIT; Head and neck melanoma; Imatinib; Ipilimumab; Mucosal melanoma; Vemurafenib; Vulvovaginal melanoma

Indexed keywords

ALPHA INTERFERON; ALPHA2B INTERFERON; B RAF KINASE; CISPLATIN; DACARBAZINE; DASATINIB; EVEROLIMUS; IMATINIB; INTERLEUKIN 2; IPILIMUMAB; NILOTINIB; PLACEBO; PROTEIN KINASE B INHIBITOR; STEM CELL FACTOR RECEPTOR; VEMURAFENIB; VINBLASTINE;

EID: 84870554279     PISSN: 15233790     EISSN: 15346269     Source Type: Journal    
DOI: 10.1007/s11912-012-0244-x     Document Type: Article
Times cited : (119)

References (67)
  • 1
    • 13944274877 scopus 로고    scopus 로고
    • Incidence of noncutaneous melanomas in the U.S
    • McLaughlin CC, Wu XC, Jemal A, et al. Incidence of noncutaneous melanomas in the U.S. Cancer. 2005;103:1000-7.
    • (2005) Cancer. , vol.103 , pp. 1000-7
    • McLaughlin, C.C.1    Wu, X.C.2    Jemal, A.3
  • 3
    • 0032531854 scopus 로고    scopus 로고
    • The National Cancer Data Base report on cutaneous and noncutaneous melanoma: A summary of 84,836 cases from the past decade. The American College of Surgeons Commission on Cancer and the American Cancer Society
    • Chang AE, Karnell LH, Menck HR. The National Cancer Data Base report on cutaneous and noncutaneous melanoma: A summary of 84,836 cases from the past decade. The American College of Surgeons Commission on Cancer and the American Cancer Society. Cancer. 1998;83:1664-78.
    • (1998) Cancer. , vol.83 , pp. 1664-78
    • Chang, A.E.1    Karnell, L.H.2    Menck, H.R.3
  • 5
    • 0037823197 scopus 로고    scopus 로고
    • Epidemiologic evidence for different roles of ultraviolet A and B radiation in melanoma mortality rates
    • Garland CF, Garland FC, Gorham ED. Epidemiologic evidence for different roles of ultraviolet A and B radiation in melanoma mortality rates. Ann Epidemiol. 2003;13:395-404.
    • (2003) Ann Epidemiol. , vol.13 , pp. 395-404
    • Garland, C.F.1    Garland, F.C.2    Gorham, E.D.3
  • 6
    • 0016210010 scopus 로고
    • Primary malignant melanoma of the oral cavity in Japan. With special reference to mucosal melanosis
    • Takagi M, Ishikawa G, MoriW. Primary malignant melanoma of the oral cavity in Japan. With special reference to mucosal melanosis. Cancer. 1974;34:358-70.
    • (1974) Cancer. , vol.34 , pp. 358-70
    • Takagi, M.1    Ishikawa, G.2    Mori, W.3
  • 7
    • 84985846647 scopus 로고
    • Epidemiologic study of excessive oral melanin pigmentation with special reference to the influence of tobacco habits
    • Axell T, Hedin CA. Epidemiologic study of excessive oral melanin pigmentation with special reference to the influence of tobacco habits. Scand J Dental Res. 1982;90:434-42.
    • (1982) Scand J Dental Res. , vol.90 , pp. 434-42
    • Axell, T.1    Hedin, C.A.2
  • 8
    • 0037225395 scopus 로고    scopus 로고
    • Mucosal melanoma of the female genital tract is a multifocal disorder
    • Lotem M, Anteby S, Peretz T, et al. Mucosal melanoma of the female genital tract is a multifocal disorder. Gynecol Oncol. 2003;88:45-50.
    • (2003) Gynecol Oncol. , vol.88 , pp. 45-50
    • Lotem, M.1    Anteby, S.2    Peretz, T.3
  • 10
    • 0033801092 scopus 로고    scopus 로고
    • Primary malignant melanoma of the male urethra
    • Watanabe J, Yamamoto S, Souma T, et al. Primary malignant melanoma of the male urethra. Int J Urol. 2000;7:3513.
    • (2000) Int J Urol , vol.7 , pp. 3513
    • Watanabe, J.1    Yamamoto, S.2    Souma, T.3
  • 11
    • 0036189813 scopus 로고    scopus 로고
    • Primary mucosal malignant melanoma of the head and neck
    • Patel SG, Prasad ML, Escrig M, et al. Primary mucosal malignant melanoma of the head and neck. Head Neck. 2002;24:247-57.
    • (2002) Head Neck. , vol.24 , pp. 247-57
    • Patel, S.G.1    Prasad, M.L.2    Escrig, M.3
  • 12
    • 55549132934 scopus 로고    scopus 로고
    • Mucosal melanomas of the head and neck: Experience of the Princess Margaret Hospital
    • Bachar G, Loh KS, O'Sullivan B, et al. Mucosal melanomas of the head and neck: Experience of the Princess Margaret Hospital. Head Neck. 2008;30:1325-31.
    • (2008) Head Neck. , vol.30 , pp. 1325-31
    • Bachar, G.1    Loh, K.S.2    O'Sullivan, B.3
  • 13
    • 1842424993 scopus 로고    scopus 로고
    • Primary mucosal melanoma of the head and neck: A proposal for microstaging localized stage I (lymph Node-negative) Tumors
    • Prasad ML, Patel SG, Huvos AG, et al. Primary mucosal melanoma of the head and neck: A proposal for microstaging localized, Stage I (lymph node-negative) tumors. Cancer. 2004;100:1657-64.
    • (2004) Cancer. , vol.100 , pp. 1657-64
    • Prasad, M.L.1    Patel, S.G.2    Huvos, A.G.3
  • 14
    • 0037407964 scopus 로고    scopus 로고
    • Sinonasal tract and nasopharyngeal melanomas: A clinicopathologic study of 115 cases with a proposed staging system
    • Thompson LD, Wieneke JA, Miettinen M. Sinonasal tract and nasopharyngeal melanomas: A clinicopathologic study of 115 cases with a proposed staging system. Am J Surg Pathol. 2003;27:594-611.
    • (2003) Am J Surg Pathol. , vol.27 , pp. 594-611
    • Thompson, L.D.1    Wieneke, J.A.2    Miettinen, M.3
  • 15
    • 84858224977 scopus 로고    scopus 로고
    • Mucosal melanoma of the head and neck
    • Pfister DG, Ang KK, Brizel DM, et al. Mucosal melanoma of the head and neck. JNCCN. 2012;10:320-38.
    • (2012) JNCCN. , vol.10 , pp. 320-38
    • Pfister, D.G.1    Ang, K.K.2    Brizel, D.M.3
  • 16
    • 31144436580 scopus 로고    scopus 로고
    • Craniofacial resection for malignant melanoma of the skull base: Report of an international collaborative study
    • Ganly I, Patel SG, Singh B, et al. Craniofacial resection for malignant melanoma of the skull base: Report of an international collaborative study. Arch Otolaryngol. 2006;132:73-8.
    • (2006) Arch Otolaryngol. , vol.132 , pp. 73-8
    • Ganly, I.1    Patel, S.G.2    Singh, B.3
  • 17
    • 73949135443 scopus 로고    scopus 로고
    • Endoscopic resection of sinonasal cancers with and without craniotomy: Oncologic results
    • Hanna E, DeMonte F, Ibrahim S, et al. Endoscopic resection of sinonasal cancers with and without craniotomy: Oncologic results. Arch Otolaryngol. 2009;135:1219-24.
    • (2009) Arch Otolaryngol. , vol.135 , pp. 1219-24
    • Hanna, E.1    DeMonte, F.2    Ibrahim, S.3
  • 18
    • 0025960706 scopus 로고
    • Mucosal melanoma of the head and neck
    • Stern SJ, Guillamondegui OM. Mucosal melanoma of the head and neck. Head Neck. 1991;13:22-7.
    • (1991) Head Neck. , vol.13 , pp. 22-7
    • Stern, S.J.1    Guillamondegui, O.M.2
  • 19
    • 33749425065 scopus 로고    scopus 로고
    • Sentinel lymph node biopsy: A new perspective in head and neck mucosal melanoma?
    • Starek I, Koranda P, Benes P. Sentinel lymph node biopsy: A new perspective in head and neck mucosal melanoma? Melanoma Res. 2006;16:423-7.
    • (2006) Melanoma Res. , vol.16 , pp. 423-7
    • Starek, I.1    Koranda, P.2    Benes, P.3
  • 20
    • 38549105719 scopus 로고    scopus 로고
    • Adjuvant therapy of melanoma
    • Shah GD, Chapman PB. Adjuvant therapy of melanoma. Cancer J. 2007;13:217-22.
    • (2007) Cancer J. , vol.13 , pp. 217-22
    • Shah, G.D.1    Chapman, P.B.2
  • 21
    • 33749053823 scopus 로고    scopus 로고
    • Sentinel-node biopsy or nodal observation in melanoma
    • Morton DL, Thompson JF, Cochran AJ, et al. Sentinel-node biopsy or nodal observation in melanoma. N Engl J Med. 2006;355:1307-17.
    • (2006) N Engl J Med. , vol.355 , pp. 1307-17
    • Morton, D.L.1    Thompson, J.F.2    Cochran, A.J.3
  • 22
    • 0030763625 scopus 로고    scopus 로고
    • Malignant mucosal melanoma of the head and neck: Review of the literature and report of 14 patients
    • Manolidis S, Donald PJ. Malignant mucosal melanoma of the head and neck: Review of the literature and report of 14 patients. Cancer. 1997;80:1373-86.
    • (1997) Cancer. , vol.80 , pp. 1373-86
    • Manolidis, S.1    Donald, P.J.2
  • 23
    • 12344297297 scopus 로고    scopus 로고
    • Postoperative radiotherapy for primary mucosal melanoma of the head and neck
    • Temam S, Mamelle G, Marandas P, et al. Postoperative radiotherapy for primary mucosal melanoma of the head and neck. Cancer. 2005;103:313-9.
    • (2005) Cancer. , vol.103 , pp. 313-9
    • Temam, S.1    Mamelle, G.2    Marandas, P.3
  • 24
    • 57349111846 scopus 로고    scopus 로고
    • Head and neck mucosal melanoma: Experience with 42 patients, with emphasis on the role of postoperative radiotherapy
    • Meleti M, Leemans CR, de Bree R, et al. Head and neck mucosal melanoma: Experience with 42 patients, with emphasis on the role of postoperative radiotherapy. Head Neck. 2008;30:1543-51.
    • (2008) Head Neck. , vol.30 , pp. 1543-51
    • Meleti, M.1    Leemans, C.R.2    De Bree, R.3
  • 25
    • 77953337213 scopus 로고    scopus 로고
    • Radiotherapy after surgical resection for head and neck mucosal melanoma
    • Wu AJ, Gomez J, Zhung JE, et al. Radiotherapy after surgical resection for head and neck mucosal melanoma. Am J Clin Oncol. 2010;33:281-5.
    • (2010) Am J Clin Oncol. , vol.33 , pp. 281-5
    • Wu, A.J.1    Gomez, J.2    Zhung, J.E.3
  • 26
    • 59549083657 scopus 로고    scopus 로고
    • Primary melanomas of the esophagus and anorectum: Epidemiologic comparison with melanoma of the skin
    • Cote TR, Sobin LH. Primary melanomas of the esophagus and anorectum: Epidemiologic comparison with melanoma of the skin. Melanoma Res. 2009;19:58-60.
    • (2009) Melanoma Res. , vol.19 , pp. 58-60
    • Cote, T.R.1    Sobin, L.H.2
  • 27
    • 74649085318 scopus 로고    scopus 로고
    • Practice patterns and outcomes for anorectal melanoma in the USA, reviewing 3 decades of treatment: Is more extensive surgical resection beneficial in all patients?
    • Iddings DM, Fleisig AJ, Chen SL, et al. Practice patterns and outcomes for anorectal melanoma in the USA, reviewing 3 decades of treatment: Is more extensive surgical resection beneficial in all patients? Ann Surg Oncol. 2010;17:40-4.
    • (2010) Ann Surg Oncol. , vol.17 , pp. 40-4
    • Iddings, D.M.1    Fleisig, A.J.2    Chen, S.L.3
  • 28
    • 0028942087 scopus 로고
    • Anorectal melanoma. A 64-year experience at memorial sloan-kettering cancer center
    • Brady MS, Kavolius JP, Quan SH. Anorectal melanoma. A 64-year experience at Memorial Sloan-Kettering Cancer Center. Dis Colon Rectum. 1995;38:146-51.
    • (1995) Dis Colon Rectum. , vol.38 , pp. 146-51
    • Brady, M.S.1    Kavolius, J.P.2    Quan, S.H.3
  • 29
    • 33751335627 scopus 로고    scopus 로고
    • The role of abdominoperineal resection as surgical therapy for anorectal melanoma
    • Yeh JJ, Shia J, Hwu WJ, et al. The role of abdominoperineal resection as surgical therapy for anorectal melanoma. Ann Surg. 2006;244:1012-7.
    • (2006) Ann Surg. , vol.244 , pp. 1012-7
    • Yeh, J.J.1    Shia, J.2    Hwu, W.J.3
  • 30
    • 4444365871 scopus 로고    scopus 로고
    • Surgical management of primary anorectal melanoma
    • Pessaux P, Pocard M, Elias D, et al. Surgical management of primary anorectal melanoma. Br J Surg. 2004;91:1183-7.
    • (2004) Br J Surg. , vol.91 , pp. 1183-7
    • Pessaux, P.1    Pocard, M.2    Elias, D.3
  • 31
    • 0036896396 scopus 로고    scopus 로고
    • Sphincter-sparing local excision and adjuvant radiation for anal-rectal melanoma
    • Ballo MT, Gershenwald JE, Zagars GK, et al. Sphincter-sparing local excision and adjuvant radiation for anal-rectal melanoma. J Clin Oncol. 2002;20:4555-8.
    • (2002) J Clin Oncol. , vol.20 , pp. 4555-8
    • Ballo, M.T.1    Gershenwald, J.E.2    Zagars, G.K.3
  • 32
    • 80053926026 scopus 로고    scopus 로고
    • Sphincter-sparing local excision and hypofractionated radiation therapy for anorectal melanoma: A 20-year experience
    • Kelly P, Zagars GK, Cormier JN, et al. Sphincter-sparing local excision and hypofractionated radiation therapy for anorectal melanoma: A 20-year experience. Cancer. 2011;117:4747-55.
    • (2011) Cancer. , vol.117 , pp. 4747-55
    • Kelly, P.1    Zagars, G.K.2    Cormier, J.N.3
  • 33
    • 0033214160 scopus 로고    scopus 로고
    • Malignant melanoma of the vulva in a nationwide, 25-year study of 219 Swedish females: Clinical observations and histopathologic features
    • Ragnarsson-Olding BK, Kanter-Lewensohn LR, Lagerlof B, et al. Malignant melanoma of the vulva in a nationwide, 25-year study of 219 Swedish females: Clinical observations and histopathologic features. Cancer. 1999;86:1273-84.
    • (1999) Cancer. , vol.86 , pp. 1273-84
    • Ragnarsson-Olding, B.K.1    Kanter-Lewensohn, L.R.2    Lagerlof, B.3
  • 34
    • 0028535363 scopus 로고
    • Malignant melanoma of the vulva and vagina in the United States: Patterns of incidence and population-based estimates of survival
    • Weinstock MA. Malignant melanoma of the vulva and vagina in the United States: Patterns of incidence and population-based estimates of survival. Am J Obstet Gynecol. 1994;171:1225-30.
    • (1994) Am J Obstet Gynecol. , vol.171 , pp. 1225-30
    • Weinstock, M.A.1
  • 35
    • 34548463077 scopus 로고    scopus 로고
    • Vulvar melanoma: A multivariable analysis of 644 patients
    • Sugiyama VE, Chan JK, Shin JY, et al. Vulvar melanoma: A multivariable analysis of 644 patients. Obstet Gynecol. 2007;110 (2 Pt 1):296-301.
    • (2007) Obstet Gynecol. , vol.110 , Issue.2 PART 1 , pp. 296-301
    • Sugiyama, V.E.1    Chan, J.K.2    Shin, J.Y.3
  • 36
    • 0035986026 scopus 로고    scopus 로고
    • Primary malignant melanoma of the vagina: Case report and review of literature
    • Piura B, Rabinovich A, Yanai-Inbar I. Primary malignant melanoma of the vagina: Case report and review of literature. Eur J Gynaecol Oncol. 2002;23:195-8.
    • (2002) Eur J Gynaecol Oncol. , vol.23 , pp. 195-8
    • Piura, B.1    Rabinovich, A.2    Yanai-Inbar, I.3
  • 37
    • 0014868767 scopus 로고
    • Malignant melanoma of the skin of the head and neck. An analysis of 405 cases
    • Ballantyne AJ. Malignant melanoma of the skin of the head and neck. An analysis of 405 cases. Am J Surg. 1970;120:425-31.
    • (1970) Am J Surg. , vol.120 , pp. 425-31
    • Ballantyne, A.J.1
  • 40
    • 0037080270 scopus 로고    scopus 로고
    • Vulvar melanoma: Is there a role for sentinel lymph node biopsy?
    • de Hullu JA, Hollema H, Hoekstra HJ, et al. Vulvar melanoma: Is there a role for sentinel lymph node biopsy? Cancer. 2002;94:48691.
    • (2002) Cancer , vol.94 , pp. 48691
    • De Hullu, J.A.1    Hollema, H.2    Hoekstra, H.J.3
  • 41
    • 34248358598 scopus 로고    scopus 로고
    • Utility of sentinel node biopsy in vulvar and vaginal melanoma: Report of 2 cases and review of the literature
    • Dhar KK, Das N, Brinkman DA, et al. Utility of sentinel node biopsy in vulvar and vaginal melanoma: Report of 2 cases and review of the literature. Int J Gynecol Cancer. 2007;17:720-3.
    • (2007) Int J Gynecol Cancer. , vol.17 , pp. 720-3
    • Dhar, K.K.1    Das, N.2    Brinkman, D.A.3
  • 42
    • 34447537724 scopus 로고    scopus 로고
    • Prognosis of primary mucosal penile melanoma: A series of 19 Dutch patients and 47 patients from the literature
    • van Geel AN, den Bakker MA, Kirkels W, et al. Prognosis of primary mucosal penile melanoma: A series of 19 Dutch patients and 47 patients from the literature. Urology. 2007;70:143-7.
    • (2007) Urology. , vol.70 , pp. 143-7
    • Van Geel, A.N.1    Den Bakker, M.A.2    Kirkels, W.3
  • 43
    • 0023697067 scopus 로고
    • Primary malignant melanoma of the gall bladder
    • Heath DI, Womack C. Primary malignant melanoma of the gall bladder. J Clin Pathol. 1988;41:1073-7.
    • (1988) J Clin Pathol. , vol.41 , pp. 1073-7
    • Heath, D.I.1    Womack, C.2
  • 44
    • 0027688469 scopus 로고
    • Primary malignant melanoma of the gallbladder. Case report and literature review
    • Habeck JO. Primary malignant melanoma of the gallbladder. Case report and literature review. Zentralbl Pathol. 1993;139:367-71.
    • (1993) Zentralbl Pathol. , vol.139 , pp. 367-71
    • Habeck, J.O.1
  • 45
    • 0032907504 scopus 로고    scopus 로고
    • Malignant melanoma of the oesophagus: Clinicopathological features, lack of p53 expression and steroid receptors and a review of the literature
    • Lam KY, Law S, Wong J. Malignant melanoma of the oesophagus: Clinicopathological features, lack of p53 expression and steroid receptors and a review of the literature. Eur J Surg Oncol. 1999;25:168-72.
    • (1999) Eur J Surg Oncol. , vol.25 , pp. 168-72
    • Lam, K.Y.1    Law, S.2    Wong, J.3
  • 46
  • 48
    • 79955591478 scopus 로고    scopus 로고
    • Dacarbazine-based chemotherapy as first-line treatment in noncutaneous metastatic melanoma: Multicenter, retrospective analysis in Asia
    • Yi JH, Yi SY, Lee HR, et al. Dacarbazine-based chemotherapy as first-line treatment in noncutaneous metastatic melanoma: Multicenter, retrospective analysis in Asia. Melanoma Res. 2011;21:223-7.
    • (2011) Melanoma Res. , vol.21 , pp. 223-7
    • Yi, J.H.1    Yi, S.Y.2    Lee, H.R.3
  • 49
    • 57349126400 scopus 로고    scopus 로고
    • Biochemotherapy in patients with advanced head and neck mucosal melanoma
    • Bartell HL, Bedikian AY, Papadopoulos NE, et al. Biochemotherapy in patients with advanced head and neck mucosal melanoma. Head Neck. 2008;30:1592-8.
    • (2008) Head Neck. , vol.30 , pp. 1592-8
    • Bartell, H.L.1    Bedikian, A.Y.2    Papadopoulos, N.E.3
  • 50
    • 12144291500 scopus 로고    scopus 로고
    • Biochemotherapy in patients with metastatic anorectal mucosal melanoma
    • Kim KB, Sanguino AM, Hodges C, et al. Biochemotherapy in patients with metastatic anorectal mucosal melanoma. Cancer. 2004;100:1478-83.
    • (2004) Cancer. , vol.100 , pp. 1478-83
    • Kim, K.B.1    Sanguino, A.M.2    Hodges, C.3
  • 51
    • 13544270173 scopus 로고    scopus 로고
    • Biochemotherapy in patients with advanced vulvovaginal mucosal melanoma
    • Harting MS, Kim KB. Biochemotherapy in patients with advanced vulvovaginal mucosal melanoma. Melanoma Res. 2004;14:517-20.
    • (2004) Melanoma Res. , vol.14 , pp. 517-20
    • Harting, M.S.1    Kim, K.B.2
  • 52
    • 36849061558 scopus 로고    scopus 로고
    • Chemotherapy compared with biochemotherapy for the treatment of metastatic melanoma: A meta-analysis of 18 trials involving 2621 patients
    • Ives NJ, Stowe RL, Lorigan P, et al. Chemotherapy compared with biochemotherapy for the treatment of metastatic melanoma: A meta-analysis of 18 trials involving 2621 patients. J Clin Oncol. 2007;25:5426-34.
    • (2007) J Clin Oncol. , vol.25 , pp. 5426-34
    • Ives, N.J.1    Stowe, R.L.2    Lorigan, P.3
  • 53
    • 53949108399 scopus 로고    scopus 로고
    • Phase III trial comparing concurrent biochemotherapy with cisplatin, vinblastine, dacarbazine, interleukin-2, and interferon alfa-2b with cisplatin, vinblastine, and dacarbazine alone in patients with metastatic malignant melanoma (E3695): A trial coordinated by the Eastern Cooperative Oncology Group
    • Atkins MB, Hsu J, Lee S, et al. Phase III trial comparing concurrent biochemotherapy with cisplatin, vinblastine, dacarbazine, interleukin-2, and interferon alfa-2b with cisplatin, vinblastine, and dacarbazine alone in patients with metastatic malignant melanoma (E3695): A trial coordinated by the Eastern Cooperative Oncology Group. J Clin Oncol. 2008;26:5748-54.
    • (2008) J Clin Oncol. , vol.26 , pp. 5748-54
    • Atkins, M.B.1    Hsu, J.2    Lee, S.3
  • 54
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma
    • First phase III study to show an improvement in overall survival for patients with metastatic melanoma. Results of this study contributed to the US FDA approval of ipilimumab
    • Hodi FS, O'Day SJ, McDermott DF, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med. 2010;363:711-23. First phase III study to show an improvement in overall survival for patients with metastatic melanoma. Results of this study contributed to the US FDA approval of ipilimumab.
    • (2010) N Engl J Med. , vol.363 , pp. 711-23
    • Hodi, F.S.1    O'Day, S.J.2    McDermott, D.F.3
  • 55
    • 79959772576 scopus 로고    scopus 로고
    • Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
    • Second phase III study to demonstrate an improvement in overall survival for patients who received ipilimumab compared to those who did not
    • Robert C, Thomas L, Bondarenko I, et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med. 2011;364:2517-26. Second phase III study to demonstrate an improvement in overall survival for patients who received ipilimumab compared to those who did not.
    • (2011) N Engl J Med. , vol.364 , pp. 2517-26
    • Robert, C.1    Thomas, L.2    Bondarenko, I.3
  • 56
    • 79959795786 scopus 로고    scopus 로고
    • Improved survival with vemurafenib in melanoma with BRAF V600E mutation
    • First demonstration of the overall survival benefit of vemurafenib, the targeted inhibitor of oncogenic BRAF
    • Chapman PB, Hauschild A, Robert C, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med. 2011;364:2507-16. First demonstration of the overall survival benefit of vemurafenib, the targeted inhibitor of oncogenic BRAF.
    • (2011) N Engl J Med. , vol.364 , pp. 2507-16
    • Chapman, P.B.1    Hauschild, A.2    Robert, C.3
  • 57
    • 18444374405 scopus 로고    scopus 로고
    • Mutations of the BRAF gene in human cancer
    • Davies H, Bignell GR, Cox C, et al. Mutations of the BRAF gene in human cancer. Nature. 2002;417:949-54.
    • (2002) Nature. , vol.417 , pp. 949-54
    • Davies, H.1    Bignell, G.R.2    Cox, C.3
  • 58
    • 27844567142 scopus 로고    scopus 로고
    • Distinct sets of genetic alterations in melanoma
    • Curtin JA, Fridlyand J, Kageshita T, et al. Distinct sets of genetic alterations in melanoma. N Engl J Med. 2005;353:2135-47.
    • (2005) N Engl J Med. , vol.353 , pp. 2135-47
    • Curtin, J.A.1    Fridlyand, J.2    Kageshita, T.3
  • 59
    • 0346728596 scopus 로고    scopus 로고
    • Determinants of BRAF mutations in primary melanomas
    • Maldonado JL, Fridlyand J, Patel H, et al. Determinants of BRAF mutations in primary melanomas. J Natl Cancer Inst. 2003;95:1878-90.
    • (2003) J Natl Cancer Inst. , vol.95 , pp. 1878-90
    • Maldonado, J.L.1    Fridlyand, J.2    Patel, H.3
  • 60
    • 33749021085 scopus 로고    scopus 로고
    • Somatic activation of KIT in distinct subtypes of melanoma
    • Curtin JA, Busam K, Pinkel D, et al. Somatic activation of KIT in distinct subtypes of melanoma. J Clin Oncol. 2006;24:4340-6.
    • (2006) J Clin Oncol. , vol.24 , pp. 4340-6
    • Curtin, J.A.1    Busam, K.2    Pinkel, D.3
  • 61
    • 37549021543 scopus 로고    scopus 로고
    • C-KIT protein expression correlated with activating mutations in KIT gene in oral mucosal melanoma
    • Rivera RS, Nagatsuka H, Gunduz M, et al. C-KIT protein expression correlated with activating mutations in KIT gene in oral mucosal melanoma. Virchows Arch. 2008;452:27-32.
    • (2008) Virchows Arch. , vol.452 , pp. 27-32
    • Rivera, R.S.1    Nagatsuka, H.2    Gunduz, M.3
  • 62
    • 42949128595 scopus 로고    scopus 로고
    • Major response to imatinib mesylate in KIT-mutated melanoma
    • Hodi FS, Friedlander P, Corless CL, et al. Major response to imatinib mesylate in KIT-mutated melanoma. J Clin Oncol. 2008;26:2046-51.
    • (2008) J Clin Oncol. , vol.26 , pp. 2046-51
    • Hodi, F.S.1    Friedlander, P.2    Corless, C.L.3
  • 63
    • 79958066836 scopus 로고    scopus 로고
    • KIT as a therapeutic target in metastatic melanoma
    • Phase II study showing the efficacy of imatinib for patients with KIT genetic aberrations, including patients with mucosal melanoma who achieved durable partial and complete responses
    • Carvajal RD, Antonescu CR, Wolchok JD, et al. KIT as a therapeutic target in metastatic melanoma. JAMA. 2011;305:2327-34. Phase II study showing the efficacy of imatinib for patients with KIT genetic aberrations, including patients with mucosal melanoma who achieved durable partial and complete responses.
    • (2011) JAMA , vol.305 , pp. 2327-34
    • Carvajal, R.D.1    Antonescu, C.R.2    Wolchok, J.D.3
  • 64
    • 79960708519 scopus 로고    scopus 로고
    • Phase II, open-label, single-arm trial of imatinib mesylate in patients with metastatic melanoma harboring c-KIT mutation or amplification
    • Phase II study showing the efficacy of imatinib for patients with KIT genetic aberrations
    • Guo J, Si L, Kong Y, et al. Phase II, open-label, single-arm trial of imatinib mesylate in patients with metastatic melanoma harboring c-KIT mutation or amplification. J Clin Oncol. 2011;29:2904-9. Phase II study showing the efficacy of imatinib for patients with KIT genetic aberrations.
    • (2011) J Clin Oncol. , vol.29 , pp. 2904-9
    • Guo, J.1    Si, L.2    Kong, Y.3
  • 65
    • 84857760658 scopus 로고    scopus 로고
    • Sunitinib therapy for melanoma patients with KIT mutations
    • Minor DR, Kashani-Sabet M, Garrido M, et al. Sunitinib therapy for melanoma patients with KIT mutations. Clin Cancer Res. 2012;18:1457-63.
    • (2012) Clin Cancer Res. , vol.18 , pp. 1457-63
    • Minor, D.R.1    Kashani-Sabet, M.2    Garrido, M.3
  • 66
    • 84863072006 scopus 로고    scopus 로고
    • Major response to everolimus in melanoma with acquired imatinib resistance
    • Si L, Xu X, Kong Y, et al. Major response to everolimus in melanoma with acquired imatinib resistance. J Clin Oncol. 2012;30:e37-40.
    • (2012) J Clin Oncol. , vol.30
    • Si, L.1    Xu, X.2    Kong, Y.3
  • 67
    • 0034085811 scopus 로고    scopus 로고
    • Relative reciprocity of NRAS and PTEN/MMAC1 alterations in cutaneous melanoma cell lines
    • Tsao H, Zhang X, Fowlkes K, et al. Relative reciprocity of NRAS and PTEN/MMAC1 alterations in cutaneous melanoma cell lines. Cancer Res. 2000;60:1800-4.
    • (2000) Cancer Res. , vol.60 , pp. 1800-4
    • Tsao, H.1    Zhang, X.2    Fowlkes, K.3


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