Hepatic progenitor cells: Another piece in the nonalcoholic fatty liver disease puzzle

Hepatology

Volumn 56, Issue 6, 2012, Pages 2013-2015

  Torres, Dawn M ^a   Harrison, Stephen A ^b  

^a WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^b SAN ANTONIO MILITARY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN 7; ETHIONINE; GLUCAGON LIKE PEPTIDE 1; INTERLEUKIN 12; RESISTIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; CELL DIVISION; CELL EXPANSION; CELL PROLIFERATION; EDITORIAL; HEPATIC PROGENITOR CELL; HISTOPATHOLOGY; INFLAMMATORY CELL; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIVER CANCER; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER INJURY; NONALCOHOLIC FATTY LIVER; NONHUMAN; OBESITY; PRIORITY JOURNAL; STELLATE CELL; STEM CELL;

FATTY LIVER; FEMALE; HUMANS; LIVER; LIVER CIRRHOSIS; MALE; STEM CELLS;

EID: 84870549181     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.25903     Document Type: Editorial

References (17)

1. Williams CD, Stengel J, Asike M, Torres DM, Shaw J, Contreras M, et al. Prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy: a prospective study. Gastroenterology 2011; 140: 124-131.
2. Kleiner DE, Brunt EM, Van Natta M, Behling C, Contos MJ, Cummings OW, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. HEPATOLOGY 2005; 41: 1313-1321.
3. Schwimmer JB, Behling C, Newbury R, Deutsch R, Nievergelt C, Schork NJ, et al. Histopathology of pediatric nonalcoholic fatty liver disease. HEPATOLOGY 2005; 42: 641-649.
4. Syn WK, Jung Y, Omenetti A, Abdelmalek M, Guy CD, Yang L, et al. Hedgehog-mediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease. Gastroenterology 2009; 137: 1478-1488.
5. Richardson MM, Jonsson JR, Powell EE, Brunt EM, Neuschwander-Tetri BA, Bhathal PS, et al. Progressive fibrosis in nonalcoholic steatohepatitis: association with altered regeneration and a ductular reaction. Gastroenterology 2007; 133: 80-90.
6. Fleig SV, Choi SS, Yang L, Jung Y, Omenetti A, VanDongen HM, et al. Hepatic accumulation of Hedgehog-reactive progenitors increases with severity of fatty liver damage in mice. Lab Invest 2007; 87: 1227-1239.
7. Nitta T, Kim JS, Mohuczy, Behrns KE. Murine cirrhosis induces hepatocyte epithelial mesenchymal transition and alterations in survival signaling pathways. HEPATOLOGY 2008; 48: 909-919.
8. Nobili V, Marcellini M, Devito R, Ciampalini P, Piemonte F, Comparcola D, et al. NAFLD in children: a prospective clinical-pathological study and effect of lifestyle advice. HEPATOLOGY 2006; 44: 458-465.
9. Nobili V, Carpino G, Alis A, Franchitto A, Alpini G, De Vito R, et al. Hepatic progenitor cells activation, fibrosis, and adipokines production in pediatric nonalcoholic fatty liver disease. HEPATOLOGY 2012; 56: 2142-2153.
10. Ziol M, Nault JC, Aout M, Barget N, Tepper M, Martin A, et al. Intermediate hepatobiliary cells predict an increased risk of hepatocarcinonogenesis in patients with hepatitis C virus-related cirrhosis. Gastroenterology 2010; 139: 335-343.
11. Polyzos SA, Toulis KA, Goulis DG, Zavos C, Kountoura J. Serum total adiponectin in nonalcoholic fatty liver disease: a systematic review and meta-analysis. Metabolism 2011; 60: 313-326.
12. Nobili V, Parkes J, Bottazzo G, Marcellini M, Cross R, Newman D, et al. Performance of ELF serum markder in predicting fibrosis stage in pediatric non-alcoholic fatty liver disease. Gastroenterology 2009; 136; 160-167.
13. Lomonaco R, Ortiz-Lopez C, Orsak B, Webb A, Hardies J, Darland C, et al. Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease. HEPATOLOGY 2012; 55: 1389-1397.
14. Tsochatzis EA, Papatheodoridis GV, Archimandritis AJ. Adipokines in nonalcoholic steatohepatitis: from pathogenesis to implications in diagnosis and therapy. Mediators Inflam 2009; 2009: 831670.
15. Roth CL, Elfers CT, Figelwicz DP. Vitamin D deficiency in obese rates exacerbates nonalcoholic fatty liver disease and increases hepatic resistin and toll-like repector activation. HEPATOLOGY 2012; 55: 1103-1111.
16. Svegliati-Baroni G, Saccomanno S, Rychlicki C, Agostinelli L, De Mincis S, Canderlaresi C, et al. Glucagon-like peptide-1 receptor activation stimulates hepatic lipid oxidation and restores hepatic signaling alteration induced by a high-fat diet in non-alcoholic steatohepatitis. Liver Int 2011; 31: 1285-1297.
17. Mells JE, Fu PP, Sharma S, Olson D, Cheng L, Handy JA, et al. Glp-1 analog, liraglutide, ameliorates hepatic steatosis and cardiac hypertrophy in C57BL/6J mice fed a Western diet. Am J Physiol Gastrointest Liver Physiol 2012; 302: G225-G235.