Endosomal proteolysis regulates calcitonin gene-related peptide responses in mesenteric arteries

British Journal of Pharmacology

Volumn 167, Issue 8, 2012, Pages 1679-1690

  McNeish, A J ^b   Roux, B T ^a   Aylett, S B ^a,d   Van Den Brink, A M ^c   Cottrell, G S ^a  

^a University of Bath   (United Kingdom)

^b UNIVERSITY OF READING   (United Kingdom)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

calcitonin gene related peptide; calcitonin receptor like receptor; endosome; endothelin converting enzyme 1; mesenteric; migraine; receptor activity modifying protein; smooth muscle cell; vasodilation

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CALCITONIN RECEPTOR LIKE RECEPTOR; CYCLIC AMP; ENDOTHELIN CONVERTING ENZYME; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN INHIBITOR; RECEPTOR ACTIVITY MODIFYING PROTEIN 1; SM 19712; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENDOSOME; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; GENE EXPRESSION; IMMUNOFLUORESCENCE TEST; MALE; MESENTERIC ARTERY; MYOGRAPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIZATION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR RESISTANCE; VASODILATATION;

ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; BLOOD PRESSURE; CALCITONIN GENE-RELATED PEPTIDE; CALCITONIN RECEPTOR-LIKE PROTEIN; CELLS, CULTURED; ENDOSOMES; MALE; MESENTERIC ARTERIES; METALLOENDOPEPTIDASES; MYOCYTES, SMOOTH MUSCLE; PROTEOLYSIS; RATS; RATS, WISTAR; RECEPTOR ACTIVITY-MODIFYING PROTEIN 1; RNA, MESSENGER; VASODILATION;

EID: 84870515632     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2012.02129.x     Document Type: Article

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