NDRG1/Cap43 overexpression in tumor tissues and serum from lung cancer patients

Journal of Cancer Research and Clinical Oncology

Volumn 138, Issue 11, 2012, Pages 1813-1820

  Wang, D ^a   Tian, X ^a   Jiang, Y ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Biological marker; Diagnostic; Lung cancer; NDRG1 Cap43

Indexed keywords

MESSENGER RNA;

ADULT; AGED; ARTICLE; BLOOD LEVEL; CANCER CELL; CANCER PATIENT; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE; GENE IDENTIFICATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG ADENOCARCINOMA; LUNG CANCER; LUNG RESECTION; MAJOR CLINICAL STUDY; MALE; N MYC DOWNSTREAM REGULATED GENE 1; PRIMARY TUMOR; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; RNA TRANSCRIPTION; SENSITIVITY AND SPECIFICITY; TISSUE SECTION;

ADENOCARCINOMA; AGED; CARCINOMA, SQUAMOUS CELL; CELL CYCLE PROTEINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUNG; LUNG NEOPLASMS; MALE; MIDDLE AGED; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84870423889     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-012-1236-9     Document Type: Article

References (27)

1. Bandyopadhyay S, Pai SK, Gross SC, Hirota S, Hosobe S, Miura K, Saito K, Commes T, Hayashi S, Watabe M, Watabe K (2003) The Drg-1 gene suppresses tumor metastasis in prostate cancer. Cancer Res 63(8): 1731-1736 (Pubitemid 36460828)
2. Bandyopadhyay S, Pai SK, Hirota S, Hosobe S, Takano Y, Saito K, Piquemal D, Commes T, Watabe M, Gross SC, Wang Y, Ran S, Watabe K (2004) Role of the putative tumor metastasis suppressor gene Drg-1 in breast cancer progression. Oncogene 23(33): 5675-5681 (Pubitemid 39093045)
3. Brundage MD, Davies D, Mackillop WJ (2002) Prognostic factors in non-small cell lung cancer: a decade of progress. Chest 122(3): 1037-1057
4. Cangul H (2004) Hypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancers. BMC Genet 5:27
5. Cangul H, Salnikow K, Yee H, Zagzag D, Commes T, Costa M (2002) Enhanced expression of a novel protein in human cancer cells: a potential aid to cancer diagnosis. Cell Biol Toxicol 18(2): 87-96 (Pubitemid 34467941)
6. Chen J, Li S, Yang Z, Lu G, Hu H (2008) Correlation between NDRG1 and PTEN expression in endometrial carcinoma. Cancer Sci 99(4): 706-710 (Pubitemid 351448073)
7. Chua MS, Sun H, Cheung ST, Mason V, Higgins J, Ross DT, Fan ST, So S (2007) Overexpression of NDRG1 is an indicator of poor prognosis in hepatocellular carcinoma. Mod Pathol 20(1): 76-83 (Pubitemid 44967952)
8. Fan C, Yu J, Liu Y, Xu H, Wang E (2010) Increased NDRG1 expression is associated with advanced T stages and poor vascularization in non-small cell lung cancer. Pathol Oncol Res
9. Fotovati A, Fujii T, Yamaguchi M, Kage M, Shirouzu K, Oie S, Basaki Y, Ono M, Yamana H, Kuwano M (2006) 17Betaestradiol induces down-regulation of Cap43/NDRG1/Drg-1, a putative differentiation-related and metastasis suppressor gene, in human breast cancer cells. Clin Cancer Res 12(10): 3010-3018 (Pubitemid 43837345)
10. Gail MH, Muenz L, McIntire KR, Radovich B, Braunstein G, Brown PR, Deftos L, Dnistrian A, Dunsmore M, Elashoff R, Geller N, Go VLW, Hirji K, Klauber MRD, Petroni G, Schwartz M, Wolfsen AR (1988) Multiple markers for lung cancer diagnosis: validation of models for localized lung cancer. J Natl Cancer Inst 80(2): 97-101
11. Greenberg AK, Lee MS (2010) Biomarkers for lung cancer: clinical uses. Curr Opin Pulm Med 13(4): 249-255 (Pubitemid 46847287)
12. Guan RJ, Ford HL, Fu Y, Li Y, Shaw LM, Pardee AB (2000) Drg-1 as a differentiation-related, putative metastatic suppressor gene in human colon cancer. Cancer Res 60(3): 749-755 (Pubitemid 30094577)
13. Jemal A, Bray F, Melissa M, Ferlay J, Ward E, Forman D (2009) Cancer statistics, 2009. CA Cancer J Clin 59(4): 225-249
14. Jemal A, Bray F et al (2011) Global cancer statistics. CA Cancer J Clin 61(2): 69-90
15. Jiang K, Shen Z, Ye Y, Yang X, Wang S (2010) A novel molecular marker for early detection and evaluating prognosis of gastric cancer: N-myc downstream regulated gene-1 (NDRG1). Scand J Gastroenterol 45(7-8): 898-908
16. Jung EU, Yoon JH, Lee YJ, Lee JH, Kim BH, Yu SJ, Myung SJ, Kim YJ, Lee HS (2010) Hypoxia and retinoic acid-inducible NDRG1 expression is responsible for doxorubicin and retinoic acid resistance in hepatocellular carcinoma cells. Cancer Lett 298(1): 9-15
17. Kalaydjieva L, Hallmayer J, Chandler D, Savov A, Nikolova A, Angelicheva D, King RH, Ishpekova B, Honeyman K, Calafell F, Shmarov A, Petrova J, Turnev I, Hristova A, Moskov M, Stancheva S, Petkova I, Bittles AH, Georgieva V, Middleton L, Thomas PK (1996) Gene mapping in Gypsies identifies a novel demyelinating neuropathy on chromosome 8q24. Nat Genet 14(2): 214-217 (Pubitemid 26338808)
18. Lachat P, Shaw P, Gebhard S, van Belzen N, Chaubert P, Bosman FT (2002) Expression of NDRG1, a differentiation-related gene, in human tissues. Histochem Cell Biol 118(5): 399-408 (Pubitemid 35352125)
19. Masuda K, Ono M, Okamoto M, Morikawa W, Otsubo M, Migita T, Tsuneyoshi M, Okuda H, Shuin T, Naito S, Kuwano M (2003) Downregulation of Cap43 gene by von Hippel-Lindau tumor suppressor protein in human renal cancer cells. Int J Cancer 105(6): 803-810 (Pubitemid 36706104)
20. Nagai MA, Gerhard R, Fregnani JH, Nonogaki S, Rierger RB, Netto MM, Soares FA (2010) Prognostic value of NDRG1 and SPARC protein expression in breast cancer patients. Breast Cancer Res Treat 126(1): 1-14
21. Nishio S, Ushijima K, Tsuda N, Takemoto S, Kawano K, Yamaguchi T, Nishida N, Kakuma T, Tsuda H, Kasamatsu T, Sasajima Y, Kage M, Kuwano M, Kamura T (2008) Cap43/NDRG1/Drg-1 is a molecular target for angiogenesis and a prognostic indicator in cervical adenocarcinoma. Cancer Lett 264(1): 36-43
22. Said HM, Stein S et al (2009) Oxygen-dependent regulation of NDRG1 in human glioblastoma cells in vitro and in vivo. Oncol Rep 21(1): 237-246
23. Sohda M, Mochida Y, Kato H, Miyazaki T, Nakajima M, Fukuchi M, Manda R, Fukai Y, Masuda N, Ono M, Kuwano M, Kuwano H (2009) Overexpression of Cap43 is associated with malignant status of esophageal cancer. Anticancer Res 29(4): 965-970
24. Stein S, Thomas EK, Herzog B, Westfall MD, Rocheleau JV, Jackson RS 2nd, Wang M, Liang P (2004) NDRG1 is necessary for p53-dependent apoptosis. J Biol Chem 279(47): 48930-48940 (Pubitemid 39625774)
25. Toffoli S, Delaive E, Dieu M, Feron O, Raes M, Michiels C (2009) NDRG1 and CRK-I/II are regulators of endothelial cell migration under Intermittent Hypoxia. Angiogenesis 12(4): 339-354
26. Zhao P, Dai M, Chen W, Li N (2010) Cancer trends in China. Jpn J Clin Oncol 40(4): 281-285
27. Zhou D, Salnikow K, Costa M (1998) Cap43, a novel gene specifically induced by Ni2 + compounds. Cancer Res 58(10): 2182-2189 (Pubitemid 28232906)