Differential regulation of tyrosine hydroxylase by continuous and intermittent hypoxia

Advances in Experimental Medicine and Biology

Volumn 758, Issue , 2012, Pages 381-385

  Raghuraman, Gayatri ^a   Prabhakar, Nanduri R ^a   Kumar, Ganesh K ^a  

^a University of Chicago   (United States)

Author keywords

Catecholamines; Chronic intermittent hypoxia; Protein kinases; Protein phosphatases; Protein phosphorylation; Reactive oxygen species; Tyrosine hydroxylase

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CATECHOLAMINE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; DOPAMINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; REACTIVE OXYGEN METABOLITE; SERINE; TYROSINE 3 MONOOXYGENASE;

CATECHOLAMINE SYNTHESIS; CONFERENCE PAPER; CONTINUOUS HYPOXIA; DISEASE DURATION; DISEASE SEVERITY; DOPAMINE BRAIN LEVEL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HUMAN; HYPOXIA; INTERMITTENT HYPOXIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REOXYGENATION; REPERFUSION INJURY;

EID: 84870419759     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-94-007-4584-1_51     Document Type: Conference Paper

References (23)

1. Bobrovskaya L, Gilligan C, Bolster EK, Flaherty JJ, Dickson PW, Dunkley PR (2007) Sustained phosphorylation of tyrosine hydroxylase at serine 40: A novel mechanism for maintenance of catecholamine synthesis. J Neurochem 100:479-489
2. Díaz-Cabiale Z, Parrado C, Fuxe K, Agnati L, Narváez JA (2007) Receptor-receptor interactions in central cardiovascular regulation. Focus on neuropeptide/alpha(2)-adrenoreceptor interactions in the nucleus tractus solitarius. J Neural Transm 114:115-125
3. Dunkley PR, Bobrovskaya L, Graham ME, von Nagy-Felsobuki EI, Dickson PW (2004) Tyrosine hydroxylase phosphorylation: Regulation and consequences. J Neurochem 91:1025-1043
4. Fitzpatrick PF (1999) Tetrahydropterin-dependent amino acid hydroxylase. Ann Rev Biochem 68:355-381
5. Gardner PR (2002) Aconitase: Sensitive target and measure of superoxide. Methods Enzymol 349:9-23
6. Gozal E, Shah ZA, Pequignot J-M, Pequignot J, Sachleben LR, Czyzyk-Krzeska MF, Li RC, Guo S-Z, Gozal D Tyrosine hydroxylase expression and activity in the rat brain: Differential regulation after long-term intermittent or sustained hypoxia. J Appl Physiol 99:642-649
7. Hanbauer I (1977) Regulation of tyrosine hydroxylase in carotid body. Adv Biochem Psychopharmacol 16:275-280
8. Hui AS, Striet JB, Gudelsky G, Soukhova GK, Gozal E, Beitner-Johnson D, Guo SZ, Sachleben LR Jr, Haycock JW, Gozal D, Czyzyk-Krzeska MF (2003) Regulation of catecholamines by sustained and intermittent hypoxia in neuroendocrine cells and sympathetic neurons. Hypertension 42:1130-1136
9. Khan SA, Nanduri J, Yuan G, Kinsman B, Kumar GK, Joseph J, Kalyanaraman B, Prabhakar NR (2011) NADPH oxidase mediates intermittent hypoxia-induced mitochondrial complex I inhibition: Relevance to lood pressure changes in rats. Antioxid Redox Signal 14:533-542
10. Kumar GK, Kim DK, Lee MS, Ramachandran R, Prabhakar NR (2003) Activation of tyrosine hydroxylase by intermittent hypoxia: Involvement of serine phosphorylation. J Appl Physiol 95:536-544
11. Kumar GK, Rai V, Sharma SD, Ramakrishnan DP, Peng YJ, Souvannakitti D, Prabhakar NR (2006) Chronic intermittent hypoxia induces hypoxia-evoked catecholamine ef fl ux in adult rat adrenal medulla via oxidative stress. J Physiol 575:229-239
12. Nyunoya T, Monick MM, Powers LS, Yarovinsky TO, Hunninghake GW (2005) Macrophages survive hyperoxia via prolonged ERK activation due to phosphatase down-regulation. J Biol Chem 280:26295-26302
13. Paulding WR, Schnell PO, Bauer AL, Striet JB, Nash JA, Kuznetsova AV, Czyzyk-Krzeska MF (2002) Regulation of gene expression for neurotransmitters during adaptation to hypoxia in oxygen-sensitive neuroendocrine cells. Microsc Res Tech 59:178-187
14. Peng YJ, Overholt JL, Kline D, Kumar GK, Prabhakar NR (2003) Induction of sensory long-term facilitation in the carotid body by intermittent hypoxia: Implications for recurrent apneas. Proc Natl Acad Sci USA 100:10073-10078
15. Pequignot JM, Cottet-Emard JM, Dalmaz Y, Peyrin L (1987) Dopamine and norepinephrine dynamics in rat carotid body during long-term hypoxia. J Auton Nerv Syst 21:9-14
16. Raghuraman G, Rai V, Peng YJ, Prabhakar NR, Kumar GK (2009) Pattern-speci fi c sustained activation of tyrosine hydroxylase by intermittent hypoxia: Role of reactive oxygen species-dependent downregulation of protein phosphatase and upregulation of protein kinases. Antioxid Redox Signal 11:1777-1789
17. Schnell PO, Ignacak ML, Bauer AL, Striet JB, Paulding WR, Czyzyk-Krzeska MF (2003) Regulation of tyrosine hydroxylase promoter activity by the von Hippel-Hindau tumor suppressor protein and hypoxia-inducible transcription factors. J Neurochem 85:483-491
18. Soulier V, Gestreau C, Borghini N, Dalmaz Y, Cottet-Emard JM, Pequignot JM (1997) Peripheral chemosensitivity and central integration: Neuroplasticity of catecholaminergic cells under hypoxia. Comp Biochem Physiol A Physiol 118:1-7
19. Souvannakitti D, Kumar GK, Fox A, Prabhakar NR (2009) Neonatal intermittent hypoxia leads to long-lasting facilitation of acute hypoxia-evoked catecholamine secretion from rat chromaf fi n cells. J Neurophysiol 101:2837-2846
20. Souvannakitti D, Nanduri J, Yuan G, Kumar GK, Fox AP, Prabhakar NR (2010) NADPH oxidase-dependent regulation of T-type Ca2+ channels and ryanodine receptors mediate the augmented exocytosis of catecholamines from intermittent hypoxia-treated neonatal rat chromaf fi n cells. J Neurosci 30:10763-10772
21. Truttmann AC, Ashraf Q, Mishra OP, Delivoria-Papadopoulos M (2004) Effect of hypoxia on protein phosphatase 2A activity, subcellular distribution and expression in cerebral cortex of newborn piglets. Neuroscience 127:355-363
22. Yuan G, Adhikary G, McCormick AA, Holcroft JJ, Kumar GK, Prabhakar NR (2004) Role of oxidative stress in intermittent hypoxia-induced immediate early gene activation in rat PC12 cells. J Physiol 557:773-783
23. Yuan G, Nanduri J, Bhasker CR, Semenza GL, Prabhakar NR (2005) Ca2+/Calmodulin kinase-dependent activation of hypoxia inducible factor 1 transcriptional activity in cells subjected to intermittent hypoxia. J Biol Chem 4321-4328