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Volumn 20, Issue 6, 2012, Pages 543-549

HER2/neu gene amplification heterogeneity: The significance of cells with a 3: 1 HER2/CEP17 ratio

Author keywords

amplification; breast carcinoma; HER2 neu; heterogeneity

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2;

EID: 84870419302     PISSN: 15412016     EISSN: 15334058     Source Type: Journal    
DOI: 10.1097/PAI.0b013e31824d04e8     Document Type: Article
Times cited : (3)

References (13)
  • 1
    • 36649015630 scopus 로고    scopus 로고
    • Fluorescence in situ hybridization (FISH) as primary methodology for the assessment of HER2 Status in adenocarcinoma of the breast: A single institution experience
    • Tubbs RR, Hicks DG, Cook J, et al. Fluorescence in situ hybridization (FISH) as primary methodology for the assessment of HER2 Status in adenocarcinoma of the breast: a single institution experience. Diagn Mol Pathol. 2007;16:207-210.
    • (2007) Diagn Mol Pathol , vol.16 , pp. 207-210
    • Tubbs, R.R.1    Hicks, D.G.2    Cook, J.3
  • 2
    • 3042622482 scopus 로고    scopus 로고
    • HER2 amplification ratios by fluorescence in situ hybridization and correlation with immunohistochemistry in a cohort of 6556 breast cancer tissues
    • Owens MA, Horten BC, Da Silva MM. HER2 amplification ratios by fluorescence in situ hybridization and correlation with immunohistochemistry in a cohort of 6556 breast cancer tissues. Clin Breast Cancer. 2004;5:63-69.
    • (2004) Clin Breast Cancer , vol.5 , pp. 63-69
    • Owens, M.A.1    Horten, B.C.2    Da Silva, M.M.3
  • 3
    • 2042467574 scopus 로고    scopus 로고
    • HER-2 testing in breast cancer using immunohistochemical analysis and fluorescence in situ hybridization: A single-institution experience of 2279 cases and comparison of dual-color and single-color scoring
    • Lal P, Salazar PA, Hudis CA, et al. HER-2 testing in breast cancer using immunohistochemical analysis and fluorescence in situ hybridization: a single-institution experience of 2279 cases and comparison of dual-color and single-color scoring. Am J Clin Pathol. 2004;121:631-636.
    • (2004) Am J Clin Pathol , vol.121 , pp. 631-636
    • Lal, P.1    Salazar, P.A.2    Hudis, C.A.3
  • 4
    • 23044475881 scopus 로고    scopus 로고
    • Analysis of intratumoral heterogeneity and amplification status in breast carcinomas with equivocal (2+) HER-2 immunostaining
    • Lewis JT, Ketterling RP, Halling KC, et al. Analysis of intratumoral heterogeneity and amplification status in breast carcinomas with equivocal (2+) HER-2 immunostaining. Am J Clin Pathol. 2005;124:273-281.
    • (2005) Am J Clin Pathol , Issue.124 , pp. 273-281
    • Lewis, J.T.1    Ketterling, R.P.2    Halling, K.C.3
  • 5
    • 0036798620 scopus 로고    scopus 로고
    • Marked intratumoral heterogeneity of c-myc and cyclinD1 but not of c-erbB2 amplification in breast cancer
    • Glockner S, Buurman H, Kleeberger W, et al. Marked intratumoral heterogeneity of c-myc and cyclinD1 but not of c-erbB2 amplification in breast cancer. Lab Invest. 2002;82:1419-1426.
    • (2002) Lab Invest , vol.82 , pp. 1419-1426
    • Glockner, S.1    Buurman, H.2    Kleeberger, W.3
  • 6
    • 64849095162 scopus 로고    scopus 로고
    • College of American Pathologists. Genetic heterogeneity in HER2 testing in breast cancer: Panel summary and guidelines
    • Vance GH, Barry TS, Bloom KJ, et al. College of American Pathologists. Genetic heterogeneity in HER2 testing in breast cancer: panel summary and guidelines. Arch Pathol Lab Med. 2009;133:611-612.
    • (2009) Arch Pathol Lab Med , vol.133 , pp. 611-612
    • Vance, G.H.1    Barry, T.S.2    Bloom, K.J.3
  • 7
    • 76449086944 scopus 로고    scopus 로고
    • Proposal of modification for the definition of genetic heterogeneity in HER2 testing in breast cancer
    • author reply 163
    • Hsu CY, Li AF, Yang CF, et al. Proposal of modification for the definition of genetic heterogeneity in HER2 testing in breast cancer. Arch Pathol Lab Med. 2010;134:162, author reply 163.
    • (2010) Arch Pathol Lab Med , vol.134 , pp. 162
    • Hsu, C.Y.1    Li, A.F.2    Yang, C.F.3
  • 8
    • 84870427417 scopus 로고    scopus 로고
    • "High-ICR" a unifying data-driven reporting system for HER2 FISH analysis based on intra-tumor heterogeneity
    • Schmidt RA, Dintzis SM, Allison KH. "High-ICR": a unifying data-driven reporting system for HER2 FISH analysis based on intra-tumor heterogeneity. Mod Pathol. 2010;62A:251.
    • (2010) Mod Pathol , vol.62 A , pp. 251
    • Schmidt, R.A.1    Dintzis, S.M.2    Allison, K.H.3
  • 9
    • 84870395191 scopus 로고    scopus 로고
    • Her2/neu genetic heterogeneity (GH) in breast cancer as defined by CAP guidelines correlates with negative prognostic factors
    • Shafi H, Schmidt M, Bose S. Her2/neu genetic heterogeneity (GH) in breast cancer as defined by CAP guidelines correlates with negative prognostic factors. Mod Pathol. 2010;63A:252.
    • (2010) Mod Pathol , vol.63 A , pp. 252
    • Shafi, H.1    Schmidt, M.2    Bose, S.3
  • 10
    • 79961007548 scopus 로고    scopus 로고
    • Heterogeneous HER2 gene amplification: Impact on patient outcome and a clinically relevant definition
    • Bartlett AI, Starcyznski J, Robson T, et al. Heterogeneous HER2 gene amplification: impact on patient outcome and a clinically relevant definition. Am J Clin Pathol. 2011;136:266-274.
    • (2011) Am J Clin Pathol , vol.136 , pp. 266-274
    • Bartlett, A.I.1    Starcyznski, J.2    Robson, T.3
  • 11
    • 34848854801 scopus 로고    scopus 로고
    • The complexity of genotypic alterations underlying HER2-positive breast cancer: An explanation for its clinical heterogeneity
    • Vanden Bempt I, Drijkoningen M, De Wolf-Peeters C. The complexity of genotypic alterations underlying HER2-positive breast cancer: an explanation for its clinical heterogeneity. Curr Opin Oncol. 2007;19:552-557.
    • (2007) Curr Opin Oncol , vol.19 , pp. 552-557
    • Vanden Bempt, I.1    Drijkoningen, M.2    De Wolf-Peeters, C.3
  • 12
    • 0035864901 scopus 로고    scopus 로고
    • Clone heterogeneity in diploid and aneuploid breast carcinomas as detected by FISH
    • Farabegoli F, Santini D, Ceccarelli C, et al. Clone heterogeneity in diploid and aneuploid breast carcinomas as detected by FISH. Cytometry. 2001;46:50-56.
    • (2001) Cytometry , vol.46 , pp. 50-56
    • Farabegoli, F.1    Santini, D.2    Ceccarelli, C.3
  • 13
    • 84870427773 scopus 로고    scopus 로고
    • Genetic heterogeneity in HER2 testing revisited: How nonuniform are "genetically heterogeneous" tumors? A study of 1550 HER2 FISH cases
    • Abstract 213
    • Malowany JI, Mazurkiewicz J, Wood M, et al. Genetic heterogeneity in HER2 testing revisited: how nonuniform are "genetically heterogeneous" tumors? A study of 1550 HER2 FISH Cases. Mod Pathol. 2011;53A. Abstract 213.
    • (2011) Mod Pathol , vol.53 A
    • Malowany, J.I.1    Mazurkiewicz, J.2    Wood, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.