Identification of collagen binding domain residues that govern catalytic activities of matrix metalloproteinase-2 (MMP-2)

Matrix Biology

Volumn 31, Issue 7-8, 2012, Pages 380-388

  Mikhailova, Margarita ^a   Xu, Xiaoping ^a   Robichaud, Trista K ^a   Pal, Sanjay ^a   Fields, Gregg B ^b   Steffensen, Bjorn ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

Author keywords

Exosite; Gelatin; Gelatinolysis; Matrix metalloproteinase 2; MMP 2; Proteolysis

Indexed keywords

ALANINE; COLLAGEN BINDING PROTEIN; ENZYME VARIANT; FIBRONECTIN; GELATIN; GELATINASE A; HYDROLYASE; RECOMBINANT ENZYME;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CATALYSIS; CIRCULAR DICHROISM; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MODIFICATION; ENZYME SUBSTRATE; FLUORESCENCE RESONANCE ENERGY TRANSFER; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; WILD TYPE;

BINDING SITES; CATALYSIS; CIRCULAR DICHROISM; COLLAGEN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GELATIN; HUMANS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE INHIBITORS; MODELS, MOLECULAR; POINT MUTATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

EID: 84870389311     PISSN: 0945053X     EISSN: 15691802     Source Type: Journal    
DOI: 10.1016/j.matbio.2012.10.001     Document Type: Article

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