-
1
-
-
79551592245
-
Mirnome analysis reveals novel molecular determinants in the pathogenesis of diet-induced nonalcoholic fatty liver disease
-
Alisi A., et al. Mirnome analysis reveals novel molecular determinants in the pathogenesis of diet-induced nonalcoholic fatty liver disease. Lab. Invest. 2011, 91:283-293.
-
(2011)
Lab. Invest.
, vol.91
, pp. 283-293
-
-
Alisi, A.1
-
2
-
-
33645884425
-
Liver adenosine monophosphate-activated kinase-alpha2 catalytic subunit is a key target for the control of hepatic glucose production by adiponectin and leptin but not insulin
-
Andreelli F., et al. Liver adenosine monophosphate-activated kinase-alpha2 catalytic subunit is a key target for the control of hepatic glucose production by adiponectin and leptin but not insulin. Endocrinology 2006, 147:2432-2441.
-
(2006)
Endocrinology
, vol.147
, pp. 2432-2441
-
-
Andreelli, F.1
-
3
-
-
0034069495
-
Gene ontology: tool for the unification of biology. The Gene Ontology Consortium
-
Ashburner M., et al. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat. Genet. 2000, 25:25-29.
-
(2000)
Nat. Genet.
, vol.25
, pp. 25-29
-
-
Ashburner, M.1
-
4
-
-
79955368052
-
The PPARbeta/delta activator GW501516 prevents the down-regulation of AMPK caused by a high-fat diet in liver and amplifies the PGC-1alpha-Lipin 1-PPARalpha pathway leading to increased fatty acid oxidation
-
Barroso E., et al. The PPARbeta/delta activator GW501516 prevents the down-regulation of AMPK caused by a high-fat diet in liver and amplifies the PGC-1alpha-Lipin 1-PPARalpha pathway leading to increased fatty acid oxidation. Endocrinology 2011, 152:1848-1859.
-
(2011)
Endocrinology
, vol.152
, pp. 1848-1859
-
-
Barroso, E.1
-
5
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
6
-
-
0035029874
-
Effect of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats
-
Bergeron R., et al. Effect of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats. Diabetes 2001, 50:1076-1082.
-
(2001)
Diabetes
, vol.50
, pp. 1076-1082
-
-
Bergeron, R.1
-
7
-
-
78449297894
-
The guardians of the genome (p53, TA-p73, and TA-p63) are regulators of tumor suppressor miRNAs network
-
Boominathan L. The guardians of the genome (p53, TA-p73, and TA-p63) are regulators of tumor suppressor miRNAs network. Cancer Metastasis Rev. 2010, 29:613-639.
-
(2010)
Cancer Metastasis Rev.
, vol.29
, pp. 613-639
-
-
Boominathan, L.1
-
9
-
-
33847205295
-
GENECODIS: a web-based tool for finding significant concurrent annotations in gene lists
-
Carmona-Saez P., Chagoyen M., Tirado F., Carazo J.M., Pascual-Montano A. GENECODIS: a web-based tool for finding significant concurrent annotations in gene lists. Genome Biol. 2007, 8:R3.
-
(2007)
Genome Biol.
, vol.8
-
-
Carmona-Saez, P.1
Chagoyen, M.2
Tirado, F.3
Carazo, J.M.4
Pascual-Montano, A.5
-
10
-
-
79960685445
-
A role for miR-296 in the regulation of lipoapoptosis by targeting PUMA
-
Cazanave S.C., et al. A role for miR-296 in the regulation of lipoapoptosis by targeting PUMA. J. Lipid Res. 2011, 52:1517-1525.
-
(2011)
J. Lipid Res.
, vol.52
, pp. 1517-1525
-
-
Cazanave, S.C.1
-
11
-
-
84858213557
-
MicroRNA profiling in murine liver after partial hepatectomy
-
Chaveles I., et al. MicroRNA profiling in murine liver after partial hepatectomy. Int. J. Mol. Med. 2012, 29:747-755.
-
(2012)
Int. J. Mol. Med.
, vol.29
, pp. 747-755
-
-
Chaveles, I.1
-
12
-
-
58149386462
-
Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expression
-
Cheung O., et al. Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expression. Hepatology 2008, 48:1810-1820.
-
(2008)
Hepatology
, vol.48
, pp. 1810-1820
-
-
Cheung, O.1
-
13
-
-
85047689953
-
5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?
-
Corton J.M., Gillespie J.G., Hawley S.A., Hardie D.G. 5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?. Eur. J. Biochem. 1995, 229:558-565.
-
(1995)
Eur. J. Biochem.
, vol.229
, pp. 558-565
-
-
Corton, J.M.1
Gillespie, J.G.2
Hawley, S.A.3
Hardie, D.G.4
-
14
-
-
42249093319
-
LNA-mediated microRNA silencing in non-human primates
-
Elmen J., et al. LNA-mediated microRNA silencing in non-human primates. Nature 2008, 452:896-899.
-
(2008)
Nature
, vol.452
, pp. 896-899
-
-
Elmen, J.1
-
15
-
-
33645075443
-
MiR-122 regulation of lipid metabolism revealed by in vivo antisense targeting
-
Esau C., et al. miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. Cell Metab. 2006, 3:87-98.
-
(2006)
Cell Metab.
, vol.3
, pp. 87-98
-
-
Esau, C.1
-
16
-
-
38649105459
-
MiR-122 targeting with LNA/2'-O-methyl oligonucleotide mixmers, peptide nucleic acids (PNA), and PNA-peptide conjugates
-
Fabani M.M., Gait M.J. miR-122 targeting with LNA/2'-O-methyl oligonucleotide mixmers, peptide nucleic acids (PNA), and PNA-peptide conjugates. RNA 2008, 14:336-346.
-
(2008)
RNA
, vol.14
, pp. 336-346
-
-
Fabani, M.M.1
Gait, M.J.2
-
17
-
-
77954933558
-
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
-
Foretz M., et al. Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state. J. Clin. Invest. 2010, 120:2355-2369.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 2355-2369
-
-
Foretz, M.1
-
18
-
-
77952299722
-
MiR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma
-
Furuta M., Kozaki K.I., Tanaka S., Arii S., Imoto I., Inazawa J. miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. Carcinogenesis 2010, 31:766-776.
-
(2010)
Carcinogenesis
, vol.31
, pp. 766-776
-
-
Furuta, M.1
Kozaki, K.I.2
Tanaka, S.3
Arii, S.4
Imoto, I.5
Inazawa, J.6
-
19
-
-
77956790980
-
MicroRNA-451: a conditional switch controlling glioma cell proliferation and migration
-
Godlewski J., Bronisz A., Nowicki M.O., Chiocca E.A., Lawler S. microRNA-451: a conditional switch controlling glioma cell proliferation and migration. Cell Cycle 2010, 9:2742-2748.
-
(2010)
Cell Cycle
, vol.9
, pp. 2742-2748
-
-
Godlewski, J.1
Bronisz, A.2
Nowicki, M.O.3
Chiocca, E.A.4
Lawler, S.5
-
20
-
-
77649259296
-
MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells
-
Godlewski J., et al. MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells. Mol. Cell 2010, 37:620-632.
-
(2010)
Mol. Cell
, vol.37
, pp. 620-632
-
-
Godlewski, J.1
-
21
-
-
34250805982
-
MicroRNA targeting specificity in mammals: determinants beyond seed pairing
-
Grimson A., Farh K.K., Johnston W.K., Garrett-Engele P., Lim L.P., Bartel D.P. MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol. Cell 2007, 27:91-105.
-
(2007)
Mol. Cell
, vol.27
, pp. 91-105
-
-
Grimson, A.1
Farh, K.K.2
Johnston, W.K.3
Garrett-Engele, P.4
Lim, L.P.5
Bartel, D.P.6
-
22
-
-
35649011441
-
Overexpression of micro ribonucleic acid 29, highly up-regulated in diabetic rats, leads to insulin resistance in 3T3-L1 adipocytes
-
He A., Zhu L., Gupta N., Chang Y., Fang F. Overexpression of micro ribonucleic acid 29, highly up-regulated in diabetic rats, leads to insulin resistance in 3T3-L1 adipocytes. Mol. Endocrinol. 2007, 21:2785-2794.
-
(2007)
Mol. Endocrinol.
, vol.21
, pp. 2785-2794
-
-
He, A.1
Zhu, L.2
Gupta, N.3
Chang, Y.4
Fang, F.5
-
23
-
-
77952099464
-
Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes
-
Herrera B.M., et al. Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes. Diabetologia 2010, 53:1099-1109.
-
(2010)
Diabetologia
, vol.53
, pp. 1099-1109
-
-
Herrera, B.M.1
-
24
-
-
0025066941
-
More powerful procedures for multiple significance testing
-
Hochberg Y., Benjamini Y. More powerful procedures for multiple significance testing. Stat. Med. 1990, 9:811-818.
-
(1990)
Stat. Med.
, vol.9
, pp. 811-818
-
-
Hochberg, Y.1
Benjamini, Y.2
-
25
-
-
0032704115
-
Chronic activation of 5'-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle
-
Holmes B.F., Kurth-Kraczek E.J., Winder W.W. Chronic activation of 5'-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle. J. Appl. Physiol. 1999, 87:1990-1995.
-
(1999)
J. Appl. Physiol.
, vol.87
, pp. 1990-1995
-
-
Holmes, B.F.1
Kurth-Kraczek, E.J.2
Winder, W.W.3
-
26
-
-
24744467150
-
Triacylglycerol-mediated oxidative stress inhibits nitric oxide production in rat isolated hepatocytes
-
Ilan E., Tirosh O., Madar Z. Triacylglycerol-mediated oxidative stress inhibits nitric oxide production in rat isolated hepatocytes. J. Nutr. 2005, 135:2090-2095.
-
(2005)
J. Nutr.
, vol.135
, pp. 2090-2095
-
-
Ilan, E.1
Tirosh, O.2
Madar, Z.3
-
27
-
-
77952707662
-
MicroRNA-370 controls the expression of microRNA-122 and Cpt1alpha and affects lipid metabolism
-
Iliopoulos D., Drosatos K., Hiyama Y., Goldberg I.J., Zannis V.I. MicroRNA-370 controls the expression of microRNA-122 and Cpt1alpha and affects lipid metabolism. J. Lipid Res. 2010, 51:1513-1523.
-
(2010)
J. Lipid Res.
, vol.51
, pp. 1513-1523
-
-
Iliopoulos, D.1
Drosatos, K.2
Hiyama, Y.3
Goldberg, I.J.4
Zannis, V.I.5
-
28
-
-
84155186597
-
A phenotypic screen to identify hypertrophy-modulating microRNAs in primary cardiomyocytes
-
Jentzsch C., et al. A phenotypic screen to identify hypertrophy-modulating microRNAs in primary cardiomyocytes. J. Mol. Cell. Cardiol. 2012, 52:13-20.
-
(2012)
J. Mol. Cell. Cardiol.
, vol.52
, pp. 13-20
-
-
Jentzsch, C.1
-
29
-
-
62049083189
-
MicroRNA expression pattern in different stages of nonalcoholic fatty liver disease
-
Jin X., Ye Y.F., Chen S.H., Yu C.H., Liu J., Li Y.M. MicroRNA expression pattern in different stages of nonalcoholic fatty liver disease. Dig. Liver Dis. 2009, 41:289-297.
-
(2009)
Dig. Liver Dis.
, vol.41
, pp. 289-297
-
-
Jin, X.1
Ye, Y.F.2
Chen, S.H.3
Yu, C.H.4
Liu, J.5
Li, Y.M.6
-
30
-
-
14044251458
-
Human MicroRNA targets
-
John B., Enright A.J., Aravin A., Tuschl T., Sander C., Marks D.S. Human MicroRNA targets. PLoS Biol. 2004, 2:e363.
-
(2004)
PLoS Biol.
, vol.2
-
-
John, B.1
Enright, A.J.2
Aravin, A.3
Tuschl, T.4
Sander, C.5
Marks, D.S.6
-
31
-
-
39849096995
-
Regulation of progenitor cell proliferation and granulocyte function by microRNA-223
-
Johnnidis J.B., et al. Regulation of progenitor cell proliferation and granulocyte function by microRNA-223. Nature 2008, 451:1125-1129.
-
(2008)
Nature
, vol.451
, pp. 1125-1129
-
-
Johnnidis, J.B.1
-
32
-
-
0033982936
-
KEGG: Kyoto encyclopedia of genes and genomes
-
Kanehisa M., Goto S. KEGG: Kyoto encyclopedia of genes and genomes. Nucleic Acids Res. 2000, 28:27-30.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 27-30
-
-
Kanehisa, M.1
Goto, S.2
-
33
-
-
0035704901
-
Profiling gene expression using onto-express
-
Khatri P., Draghici S., Ostermeier G., Krawetz S. Profiling gene expression using onto-express. Genomics 2002, 79:266-270.
-
(2002)
Genomics
, vol.79
, pp. 266-270
-
-
Khatri, P.1
Draghici, S.2
Ostermeier, G.3
Krawetz, S.4
-
34
-
-
0028857136
-
Mathematical formulae for the prediction of the residual beta cell function during the first two years of disease in children and adolescents with insulin-dependent diabetes mellitus
-
Klipper-Aurbach Y., et al. Mathematical formulae for the prediction of the residual beta cell function during the first two years of disease in children and adolescents with insulin-dependent diabetes mellitus. Med Hypotheses 1995, 45:486-490.
-
(1995)
Med Hypotheses
, vol.45
, pp. 486-490
-
-
Klipper-Aurbach, Y.1
-
35
-
-
27144506185
-
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism
-
Koo S.H., et al. The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. Nature 2005, 437:1109-1111.
-
(2005)
Nature
, vol.437
, pp. 1109-1111
-
-
Koo, S.H.1
-
36
-
-
28444469246
-
Silencing of microRNAs in vivo with 'antagomirs'
-
Krutzfeldt J., et al. Silencing of microRNAs in vivo with 'antagomirs'. Nature 2005, 438:685-689.
-
(2005)
Nature
, vol.438
, pp. 685-689
-
-
Krutzfeldt, J.1
-
37
-
-
0346094457
-
Prediction of mammalian microRNA targets
-
Lewis B.P., Shih I.H., Jones-Rhoades M.W., Bartel D.P., Burge C.B. Prediction of mammalian microRNA targets. Cell 2003, 115:787-798.
-
(2003)
Cell
, vol.115
, pp. 787-798
-
-
Lewis, B.P.1
Shih, I.H.2
Jones-Rhoades, M.W.3
Bartel, D.P.4
Burge, C.B.5
-
38
-
-
77957144352
-
Genomic analysis of miRNAs in an extreme mammalian hibernator, the Arctic ground squirrel
-
Liu Y., et al. Genomic analysis of miRNAs in an extreme mammalian hibernator, the Arctic ground squirrel. Physiol. Genomics 2010, 42A:39-51.
-
(2010)
Physiol. Genomics
, vol.42 A
, pp. 39-51
-
-
Liu, Y.1
-
39
-
-
77956640400
-
MicroRNA-151 and its hosting gene FAK (focal adhesion kinase) regulate tumor cell migration and spreading of hepatocellular carcinoma
-
Luedde T. MicroRNA-151 and its hosting gene FAK (focal adhesion kinase) regulate tumor cell migration and spreading of hepatocellular carcinoma. Hepatology 2010, 52:1164-1166.
-
(2010)
Hepatology
, vol.52
, pp. 1164-1166
-
-
Luedde, T.1
-
40
-
-
62749132978
-
Oncomirs: from tumor biology to molecularly targeted anticancer strategies
-
Mocellin S., Pasquali S., Pilati P. Oncomirs: from tumor biology to molecularly targeted anticancer strategies. Mini Rev. Med. Chem. 2009, 9:70-80.
-
(2009)
Mini Rev. Med. Chem.
, vol.9
, pp. 70-80
-
-
Mocellin, S.1
Pasquali, S.2
Pilati, P.3
-
41
-
-
66349110163
-
Annotating the human genome with Disease Ontology
-
Osborne J.D., et al. Annotating the human genome with Disease Ontology. BMC Genomics 2009, 10(Suppl. 1):S6.
-
(2009)
BMC Genomics
, vol.10
, Issue.SUPPL. 1
-
-
Osborne, J.D.1
-
42
-
-
12744277951
-
5-Aminoimidazole-4-carboxamide-1-beta-d-ribofuranoside causes acute hepatic insulin resistance in vivo
-
Pencek R.R., et al. 5-Aminoimidazole-4-carboxamide-1-beta-d-ribofuranoside causes acute hepatic insulin resistance in vivo. Diabetes 2005, 54:355-360.
-
(2005)
Diabetes
, vol.54
, pp. 355-360
-
-
Pencek, R.R.1
-
43
-
-
20144386698
-
Long-term AICAR administration and exercise prevents diabetes in ZDF rats
-
Pold R., et al. Long-term AICAR administration and exercise prevents diabetes in ZDF rats. Diabetes 2005, 54:928-934.
-
(2005)
Diabetes
, vol.54
, pp. 928-934
-
-
Pold, R.1
-
44
-
-
17444415304
-
Repression of protein synthesis and mTOR signaling in rat liver mediated by the AMPK activator aminoimidazole carboxamide ribonucleoside
-
Reiter A.K., Bolster D.R., Crozier S.J., Kimball S.R., Jefferson L.S. Repression of protein synthesis and mTOR signaling in rat liver mediated by the AMPK activator aminoimidazole carboxamide ribonucleoside. Am. J. Physiol. Endocrinol. Metab. 2005, 288:E980-E988.
-
(2005)
Am. J. Physiol. Endocrinol. Metab.
, vol.288
-
-
Reiter, A.K.1
Bolster, D.R.2
Crozier, S.J.3
Kimball, S.R.4
Jefferson, L.S.5
-
45
-
-
58249107416
-
Identification of glucose-regulated miRNAs from pancreatic beta cells reveals a role for miR-30d in insulin transcription
-
Tang X., Muniappan L., Tang G., Ozcan S. Identification of glucose-regulated miRNAs from pancreatic beta cells reveals a role for miR-30d in insulin transcription. RNA 2009, 15:287-293.
-
(2009)
RNA
, vol.15
, pp. 287-293
-
-
Tang, X.1
Muniappan, L.2
Tang, G.3
Ozcan, S.4
-
46
-
-
80455143206
-
Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans
-
Timmers S., et al. Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metab. 2011, 14:612-622.
-
(2011)
Cell Metab.
, vol.14
, pp. 612-622
-
-
Timmers, S.1
-
47
-
-
61949292843
-
Evidence for LKB1/AMP-activated protein kinase/endothelial nitric oxide synthase cascade regulated by hepatocyte growth factor, S-adenosylmethionine, and nitric oxide in hepatocyte proliferation
-
Vázquez-Chantada M., et al. Evidence for LKB1/AMP-activated protein kinase/endothelial nitric oxide synthase cascade regulated by hepatocyte growth factor, S-adenosylmethionine, and nitric oxide in hepatocyte proliferation. Hepatology 2009, 49:608-617.
-
(2009)
Hepatology
, vol.49
, pp. 608-617
-
-
Vázquez-Chantada, M.1
-
48
-
-
33744544094
-
Role of hepatic AMPK activation in glucose metabolism and dexamethasone-induced regulation of AMPK expression
-
Viana A.Y., et al. Role of hepatic AMPK activation in glucose metabolism and dexamethasone-induced regulation of AMPK expression. Diabetes Res. Clin. Pract. 2006, 73:135-142.
-
(2006)
Diabetes Res. Clin. Pract.
, vol.73
, pp. 135-142
-
-
Viana, A.Y.1
-
49
-
-
58849094980
-
MicroRNA-320 expression in myocardial microvascular endothelial cells and its relationship with insulin-like growth factor-1 in type 2 diabetic rats
-
Wang X.H., Qian R.Z., Zhang W., Chen S.F., Jin H.M., Hu R.M. MicroRNA-320 expression in myocardial microvascular endothelial cells and its relationship with insulin-like growth factor-1 in type 2 diabetic rats. Clin. Exp. Pharmacol. Physiol. 2009, 36:181-188.
-
(2009)
Clin. Exp. Pharmacol. Physiol.
, vol.36
, pp. 181-188
-
-
Wang, X.H.1
Qian, R.Z.2
Zhang, W.3
Chen, S.F.4
Jin, H.M.5
Hu, R.M.6
-
50
-
-
84862777271
-
MicroRNA-122 suppresses cell proliferation and induces cell apoptosis in hepatocellular carcinoma by directly targeting Wnt/beta-catenin pathway
-
Xu J., et al. MicroRNA-122 suppresses cell proliferation and induces cell apoptosis in hepatocellular carcinoma by directly targeting Wnt/beta-catenin pathway. Liver Int. 2012, 32:752-760.
-
(2012)
Liver Int.
, vol.32
, pp. 752-760
-
-
Xu, J.1
-
51
-
-
0036851817
-
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
-
Yamauchi T., et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat. Med. 2002, 8:1288-1295.
-
(2002)
Nat. Med.
, vol.8
, pp. 1288-1295
-
-
Yamauchi, T.1
-
52
-
-
62649093597
-
AMP-activated protein kinase suppresses LXR-dependent sterol regulatory element-binding protein-1c transcription in rat hepatoma McA-RH7777 cells
-
Yang J., Craddock L., Hong S., Liu Z.M. AMP-activated protein kinase suppresses LXR-dependent sterol regulatory element-binding protein-1c transcription in rat hepatoma McA-RH7777 cells. J. Cell. Biochem. 2009, 106:414-426.
-
(2009)
J. Cell. Biochem.
, vol.106
, pp. 414-426
-
-
Yang, J.1
Craddock, L.2
Hong, S.3
Liu, Z.M.4
-
53
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou G., et al. Role of AMP-activated protein kinase in mechanism of metformin action. J. Clin. Invest. 2001, 108:1167-1174.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
|