Co-nanoencapsulation of magnetic nanoparticles and selol for breast tumor treatment: In vitro evaluation of cytotoxicity and magnetohyperthermia efficacy

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 5287-5299

  Estevanato, Luciana L C ^a   Da Silva, Jaqueline R ^a   Falqueiro, André M ^b   Mosiniewicz Szablewska, Ewa ^c   Suchocki, Piotr ^d,e   Tedesco, Antônio C ^b   Morais, Paulo C ^f   Lacava, Zulmira G M ^a  

^a INSTITUTO DE CIÊNCIAS BIOLÓGICAS   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c INSTITUTE OF PHYSICS   (Poland)

^d MEDICAL UNIVERSITY OF WARSAW   (Poland)

^e NATIONAL MEDICINES INSTITUTE   (Poland)

^f UNIVERSITY OF BRASILIA   (Brazil)

Author keywords

Cancer; Drug delivery; Maghemite nanoparticle; MTT; PLGA nanocapsule; Selenium

Indexed keywords

ANTINEOPLASTIC AGENT; MAGNETIC NANOPARTICLE; SELOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BREAST CANCER; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; ELECTROPHORETIC MOBILITY; HUMAN; HUMAN CELL; HYPERTHERMIC THERAPY; IN VITRO STUDY; MAGNETIC FIELD; MAGNETOHYPERTHERMIA THERAPY; NANOANALYSIS; NANOENCAPSULATION; NONHUMAN; PHOTON CORRELATION SPECTROSCOPY; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; COMBINED MODALITY THERAPY; FEMALE; HYPERTHERMIA, INDUCED; MAGNETITE NANOPARTICLES; MICE; NANOCAPSULES; SELENIUM COMPOUNDS; TREATMENT OUTCOME;

EID: 84870375800     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S35279     Document Type: Article

References (38)

1. Diao YY, Li HY, Fu YH, etal. Doxorubicin-loaded PEG-PCL copolymer micelles enhance cytotoxicity and intracellular accumulation of doxorubicin in adriamycin-resistant tumor cells. Int J Nanomedicine. 2011;6:1955-1962.
2. Kumar CS, Mohammad F. Magnetic nanomaterials for hyperthermia-based therapy and controlled drug delivery. Adv Drug Deliv Rev. 2011;63(9):789-808.
3. Carneiro ML, Nunes ES, Peixoto RC, etal. Free Rhodium (II) citrate and rhodium (II) citrate magnetic carriers as potential strategies for breast cancer therapy. J Nanobiotechnology. 2011;9:11.
4. Lee P, Zhang R, Li V, etal. Enhancement of anticancer efficacy using modified lipophilic nanoparticle drug encapsulation. Int J Nanomedicine. 2012;7:731-737.
5. Wolinsky JB, Colson YL, Grinstaff MW. Local drug delivery strategies for cancer treatment: gels, nanoparticles, polymeric films, rods, and wafers. J Control Release. 2012;159(1):14-26.
6. Haley B, Frenkel E. Nanoparticles for drug delivery in cancer treatment. Urol Oncol. 2008;26(1):57-64.
7. De Jong WH, Borm PJ. Drug delivery and nanoparticles: applications and hazards. Int J Nanomedicine. 2008;3(2):133-149.
8. Danhier F, Ansorena E, Silva JM, Coco R, Le Breton A, Preat V. PLGA-based nanoparticles: an overview of biomedical applications. J Control Release. 2012;161(2):505-522.
9. Danhier F, Lecouturier N, Vroman B, etal. Paclitaxel-loaded PEGylated PLGA-based nanoparticles: in vitro and in vivo evaluation. J Control Release. 2009;133(1):11-17.
10. Fonseca C, Simoes S, Gaspar R. Paclitaxel-loaded PLGA nanoparticles: preparation, physicochemical characterization and in vitro anti-tumoral activity. J Control Release. 2002;83(2):273-286.
11. Davaran S, Rashidi MR, Pourabbas B, Dadashzadeh M, Haghshenas NM. Adriamycin release from poly(lactide-coglycolide)-polyethylene glycol nanoparticles: synthesis, and in vitro characterization. Int J Nanomedicine. 2006;1(4):535-539.
12. Park J, Fong PM, Lu J, etal. PEGylated PLGA nanoparticles for the improved delivery of doxorubicin. Nanomedicine. 2009;5(4):410-418.
13. Khandhar AP, Ferguson RM, Simon JA, Krishnan KM. Tailored magnetic nanoparticles for optimizing magnetic fluid hyperthermia. J Biomed Mater Res A. 2012;100(3):728-737.
14. Portilho FA, Estevanato LLC, Miranda-Vilela AL, etal. Investigation of a magnetohyperthermia system efficacy. J Appl Phys. 2010;109:07B307.
15. Laurent S, Dutz S, Häfeli UO, Mahmoudi M. Magnetic fluid hyperthermia: focus on superparamagnetic iron oxide nanoparticles. Adv Colloid Interface Sci. 2011;166(1-2):8-23.
16. Falqueiro AM, Primo FL, Morais PC, Mosiniewicz-Szablewska E, Suchocki P, Tedesco AC. Selol-loaded magnetic nanocapsules: a new approach for hyperthermia cancer therapy. J Appl Phys. 2011;109(7):07B306.
17. Fitak B, Grabowski M, Suchocki P, inventors. Poland patent Pol. Pl 176530 (Cl. A61K31/095). June 30, 1999.
18. Brozmanova J, Manikova D, Vlckova V, Chovanec M. Selenium: a double-edged sword for defense and offence in cancer. Arch Toxicol. 2010;84(12):919-938.
19. Luo H, Wang F, Bai Y, Chen T, Zheng W. Selenium nanoparticles inhibit the growth of HeLa and MDA-MB-231cells through induction of S phase arrest. Colloids Surf B Biointerfaces. 2012;94:304-308.
20. Suchocki P, Misiewicz I, Skupinska K, Waclawek K, Fijalek Z, Kasprzycka-Guttman T. The activity of Selol in multidrug-resistant and sensitive human leukemia cells. Oncol Rep. 2007;18(4):893-899.
21. Cao S, Durrani FA, Rustum YM. Selective modulation of the therapeutic efficacy of anticancer drugs by selenium containing compounds against human tumor xenografts. Clin Cancer Res. 2004;10(7):2561-2569.
22. Bee A, Massart R, Neveu S. Synthesis of very fine maghemite particles. J Magn Magn Mater. 1995;149(1-2):6-9.
23. Lu X, Qian J, Zhou H, etal. In vitro cytotoxicity and induction of apoptosis by silica nanoparticles in human HepG2 hepatoma cells. Int J Nanomedicine. 2011;6:1889-1901.
24. Falqueiro AM, Siqueira-Moura MP, Jardim DR, etal. In vitro cytotoxicity of Selol-loaded magnetic nanaocapsules against neoplastic cell lines under AC magnetic field activation. J Appl Phys. 2012;111:07B335.
25. Simioni AR, Primo FL, Rodrigues MMA, Lacava ZGM, Morais PC, Tedesco AC. Preparation, characterization and in vitro toxicity test of magnetic nanoparticle-based drug delivery system to hyperthermia of biological tissues. IEEE Trans Magn. 2007;43(6):2459-2461.
26. Guedes MHA, Guedes MEA, Morais PC, etal. Proposal of a magnetohyperthermia system: preliminary biological tests. J Magn Magn Mater. 2004;272-276:2406-2407.
27. Dobrovolskaia MA, McNeil SE. Immunological properties of engineered nanomaterials. Nat Nanotechnol. 2007;2(8):469-478.
28. Estevanato L, Cintra D, Baldini N, etal. Preliminary biocompatibility investigation of magnetic albumin nanosphere designed as a potential versatile drug delivery system. Int J Nanomedicine. 2011;6:1709-1717.
29. Heath JR, Davis ME. Nanotechnology and cancer. Annu Rev Med. 2008;59:251-265.
30. Morais PC, Garg VK, Oliveira AC, etal. Synthesis and characterization of size-controlled cobalt-ferrite-based ionic ferrofluids. J Magn Magn Mater. 2001;225(1-2):37-40.
31. Yang F, Tang Q, Zhong X, etal. Surface decoration by Spirulina polysaccharide enhances the cellular uptake and anticancer efficacy of selenium nanoparticles. Int J Nanomedicine. 2012;7:835-844.
32. Tan L, Jia X, Jiang X, etal. In vitro study on the individual and synergistic cytotoxicity of adriamycin and selenium nanoparticles against Bel7402 cells with a quartz crystal microbalance. Biosens Bioelectron. 2009;24(7):2268-2272.
33. Chen T, Wong YS, Zheng W, Bai Y, Huang L. Selenium nanoparticles fabricated in Undaria pinnatifida polysaccharide solutions induce mitochondria-mediated apoptosis in A375 human melanoma cells. Colloids Surf B Biointerfaces. 2008;67(1):26-31.
34. Kwok JC, Richardson DR. The iron metabolism of neoplastic cells: alterations that facilitate proliferation? Crit Rev Oncol Hematol. 2002;42(1):65-78.
35. Lu J, Kaeck M, Jiang C, Wilson AC, Thompson HJ. Selenite induction of DNA strand breaks and apoptosis in mouse leukemic L1210 cells. Biochem Pharmacol. 1994;47(9):1531-1535.
36. Li S, Zhou Y, Wang R, Zhang H, Dong Y, Ip C. Selenium sensitizes MCF-7 breast cancer cells to doxorubicin-induced apoptosis through modulation of phospho-Akt and its downstream substrates. Mol Cancer Ther. 2007;6(3):1031-1038.
37. Shang D, Li Y, Wang C, Wang X, Yu Z, Fu X. A novel polysaccharide from Se-enriched Ganoderma lucidum induces apoptosis of human breast cancer cells. Oncol Rep. 2011;25(1):267-272.
38. Valdiglesias V, Pasaro E, Mendez J, Laffon B. In vitro evaluation of selenium genotoxic, cytotoxic, and protective effects: a review. Arch Toxicol. 2010;84(5):337-351.