Purification of the therapeutic antibody trastuzumab from genetically modified plants using safflower Protein A-oleosin oilbody technology

Transgenic Research

Volumn 21, Issue 6, 2012, Pages 1291-1301

  McLean, Michael D ^a,b   Chen, Rongji ^c   Yu, Deqiang ^a,b   Mah, Kor Zheng ^b   Teat, John ^b   Wang, Haifeng ^a   Zaplachinski, Steve ^c   Boothe, Joseph ^c   Hall, J Christopher ^a,b  

^a UNIVERSITY OF GUELPH   (Canada)

^b PlantForm Corp   (Canada)

^c SemBioSys Genetics Inc   (Canada)

Author keywords

Antibody; Fusion protein; Nicotiana benthamiana; Oleosin; Protein A; Purification; Safflower; Transgenic; Transient; Trastuzumab

Indexed keywords

ARABIDOPSIS PROTEIN; MONOCLONAL ANTIBODY; OLEOSIN PROTEIN, ARABIDOPSIS; PLANTIBODY; STAPHYLOCOCCUS PROTEIN A; TRASTUZUMAB;

AFFINITY CHROMATOGRAPHY; AMINO ACID SEQUENCE; ARTICLE; CELL ORGANELLE; CHEMISTRY; GENETICS; HUMAN; IMMUNOLOGY; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; SAFFLOWER; TOBACCO; TRANSGENIC PLANT;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL, HUMANIZED; ARABIDOPSIS PROTEINS; CARTHAMUS TINCTORIUS; CHROMATOGRAPHY, AFFINITY; HUMANS; MOLECULAR SEQUENCE DATA; ORGANELLES; PLANTIBODIES; PLANTS, GENETICALLY MODIFIED; STAPHYLOCOCCAL PROTEIN A; TOBACCO;

CARTHAMUS TINCTORIUS; NICOTIANA BENTHAMIANA;

EID: 84870358859     PISSN: 09628819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11248-012-9603-5     Document Type: Article

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