-
1
-
-
5044225419
-
Determinants of sensitivity and resistance to gemcitabine: The roles of human equilibrative nucleoside transporter 1 and deoxycytidine kinase in non-small cell lung cancer
-
DOI 10.1111/j.1349-7006.2004.tb03257.x
-
ACHIWA, H., OGURI, T., SATO, S., MAEDA, H., NIIMI, T., and UEDA, R. (2004). Determinants of sensitivity and resistance to gemcitabine: the roles of human equilibrative nucleoside transporter 1 and deoxycytidine kinase in non-small cell lung cancer. Cancer Sci. 95, 753-757. (Pubitemid 39335096)
-
(2004)
Cancer Science
, vol.95
, Issue.9
, pp. 753-757
-
-
Achiwa, H.1
Oguri, T.2
Sato, S.3
Maeda, H.4
Niimi, T.5
Ueda, R.6
-
2
-
-
33845723241
-
An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform
-
DOI 10.1002/anie.200602251
-
BAGALKOT, V., FAROKHZAD, O.C., LANGER, R., and JON, S. (2006). An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform. Angew Chem. Int. Ed. Engl. 45, 8149-8152. (Pubitemid 44974149)
-
(2006)
Angewandte Chemie - International Edition
, vol.45
, Issue.48
, pp. 8149-8152
-
-
Bagalkot, V.1
Farokhzad, O.C.2
Langer, R.3
Jon, S.4
-
3
-
-
67349167635
-
Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer
-
BATES, P.J., LABER, D.A., MILLER, D.M., THOMAS, S.D., and TRENT, J.O. (2009). Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer. Exp. Mol. Pathol. 86, 151-164.
-
(2009)
Exp. Mol. Pathol
, vol.86
, pp. 151-164
-
-
Bates, P.J.1
Laber, D.A.2
Miller, D.M.3
Thomas, S.D.4
Trent, J.O.5
-
4
-
-
77956650825
-
Development of aptamer therapeutics
-
BUNKA, D.H., PLATONOVA, O., and STOCKLEY, P.G. (2010). Development of aptamer therapeutics. Curr. Opin. Pharmacol. 10, 557-562.
-
(2010)
Curr. Opin. Pharmacol
, vol.10
, pp. 557-562
-
-
Bunka, D.H.1
Platonova, O.2
Stockley, P.G.3
-
5
-
-
8244254377
-
Improvements in survival and clinical benefit with gemcitabine as first- line therapy for patients with advanced pancreas cancer: A randomized trial
-
BURRIS, H.A., 3rd, MOORE, M.J., ANDERSEN, J., GREEN, M.R., ROTHENBERG, M.L., MODIANO, M.R., CRIPPS, M.C., PORTENOY, R.K., STORNIOLO, A.M., TARASSOFF, P., et al. (1997). Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J. Clin. Oncol. 15, 2403-2413. (Pubitemid 27251144)
-
(1997)
Journal of Clinical Oncology
, vol.15
, Issue.6
, pp. 2403-2413
-
-
Burris III, H.A.1
Moore, M.J.2
Andersen, J.3
Green, M.R.4
Rothenberg, M.L.5
Modiano, M.R.6
Cripps, M.C.7
Portenoy, R.K.8
Storniolo, A.M.9
Tarassoff, P.10
Nelson, R.11
Dorr, F.A.12
Stephens, C.D.13
Von Hoff, D.D.14
-
6
-
-
70349376534
-
Cell-specific aptamers for targeted therapies
-
CERCHIA, L., GIANGRANDE, P.H., MCNAMARA, J.O., and DE FRANCISCIS, V. (2009). Cell-specific aptamers for targeted therapies. Methods Mol. Biol. 535, 59-78.
-
(2009)
Methods Mol. Biol
, vol.535
, pp. 59-78
-
-
Cerchia, L.1
Giangrande, P.H.2
McNamara, J.O.3
De Franciscis, V.4
-
7
-
-
33745714275
-
Aptamer:toxin conjugates that specifically target prostate tumor cells
-
CHU, T.C., MARKS, J.W., 3RD, LAVERY, L.A., FAULKNER, S., ROSENBLUM, M.G., ELLINGTON, A.D., and LEVY, M. (2006). Aptamer:toxin conjugates that specifically target prostate tumor cells. Cancer Res. 66, 5989-5992.
-
(2006)
Cancer Res
, vol.66
, pp. 5989-5992
-
-
Chu, T.C.1
Marks III, J.W.2
Lavery, L.A.3
Faulkner, S.4
Rosenblum, M.G.5
Ellington, A.D.6
Levy, M.7
-
8
-
-
0029017988
-
Enzymatic synthesis of 2¢-modified nucleic acids: Identification of important phosphate and ribose moieties in RNase P substrates
-
CONRAD, F., HANNE, A., GAUR, R.K., and KRUPP, G. (1995). Enzymatic synthesis of 2¢-modified nucleic acids: identification of important phosphate and ribose moieties in RNase P substrates. Nucleic Acids Res. 23, 1845-1853.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 1845-1853
-
-
Conrad, F.1
Hanne, A.2
Gaur, R.K.3
Krupp, G.4
-
9
-
-
79955921754
-
FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer
-
CONROY, T., DESSEIGNE, F., YCHOU, M., BOUCHE, O., GUIMBAUD, R., BECOUARN, Y., ADENIS, A., RAOUL, J.L., GOURGOU-BOURGADE, S., DE LA FOUCHARDIERE, C., et al. (2011). FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. N. Engl. J. Med. 364, 1817-1825.
-
(2011)
N. Engl. J. Med
, vol.364
, pp. 1817-1825
-
-
Conroy, T.1
Desseigne, F.2
Ychou, M.3
Bouche, O.4
Guimbaud, R.5
Becouarn, Y.6
Adenis, A.7
Raoul, J.L.8
Gourgou-Bourgade, S.9
De La Fouchardiere, C.10
-
10
-
-
70249110439
-
Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors
-
DASSIE, J.P., LIU, X.Y., THOMAS, G.S., WHITAKER, R.M., THIEL, K.W., STOCKDALE, K.R., MEYERHOLZ, D.K., MCCAFFREY, A.P., MCNAMARA, J.O., 2nd, and GIANGRANDE, P.H. (2009). Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors. Nat. Biotechnol. 27, 839-849.
-
(2009)
Nat. Biotechnol
, vol.27
, pp. 839-849
-
-
Dassie, J.P.1
Liu, X.Y.2
Thomas, G.S.3
Whitaker, R.M.4
Thiel, K.W.5
Stockdale, K.R.6
Meyerholz, D.K.7
McCaffrey, A.P.8
McNamara II, J.O.9
Giangrande, P.H.10
-
11
-
-
0025074907
-
In vitro selection of RNA molecules that bind specific ligands
-
ELLINGTON, A.D., and SZOSTAK, J.W. (1990). In vitro selection of RNA molecules that bind specific ligands. Nature 346, 818-822.
-
(1990)
Nature
, vol.346
, pp. 818-822
-
-
Ellington, A.D.1
Szostak, J.W.2
-
12
-
-
33646582037
-
Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo
-
FAROKHZAD, O.C., CHENG, J., TEPLY, B.A., SHERIFI, I., JON, S., KANTOFF, P.W., RICHIE, J.P., and LANGER, R. (2006). Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo. Proc. Natl. Acad. Sci. U. S. A. 103, 6315-6320.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A
, vol.103
, pp. 6315-6320
-
-
Farokhzad, O.C.1
Cheng, J.2
Teply, B.A.3
Sherifi, I.4
Jon, S.5
Kantoff, P.W.6
Richie, J.P.7
Langer, R.8
-
13
-
-
47249108640
-
Kinetic investigation of the inhibitory effect of gemcitabine on DNA polymerization catalyzed by human mitochondrial DNA polymerase
-
FOWLER, J.D., BROWN, J.A., JOHNSON, K.A., and SUO, Z. (2008). Kinetic investigation of the inhibitory effect of gemcitabine on DNA polymerization catalyzed by human mitochondrial DNA polymerase. J. Biol. Chem. 283, 15339-15348.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 15339-15348
-
-
Fowler, J.D.1
Brown, J.A.2
Johnson, K.A.3
Suo, Z.4
-
14
-
-
34047273010
-
The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor AG1478 increases the formation of inactive untethered EGFR dimers: Implications for combination therapy with monoclonal antibody 806
-
DOI 10.1074/jbc.M605136200
-
GAN, H.K., WALKER, F., BURGESS, A.W., RIGOPOULOS, A., SCOTT, A.M., and JOHNS, T.G. (2007). The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor AG1478 increases the formation of inactive untethered EGFR dimers. Implications for combination therapy with monoclonal antibody 806. J. Biol. Chem. 282, 2840-2850. (Pubitemid 47084315)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.5
, pp. 2840-2850
-
-
Gan, H.K.1
Walker, F.2
Burgess, A.W.3
Rigopoulos, A.4
Scott, A.M.5
Johns, T.G.6
-
15
-
-
0027295270
-
Modification interference approach to detect ribose moieties important for the optimal activity of a ribozyme
-
GAUR, R.K., and KRUPP, G. (1993). Modification interference approach to detect ribose moieties important for the optimal activity of a ribozyme. Nucleic Acids Res. 21, 21-26. (Pubitemid 23146288)
-
(1993)
Nucleic Acids Research
, vol.21
, Issue.1
, pp. 21-26
-
-
Gaur, R.K.1
Krupp, G.2
-
16
-
-
33645731188
-
Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine
-
GIOVANNETTI, E., DEL TACCA, M., MEY, V., FUNEL, N., NANNIZZI, S., RICCI, S., ORLANDINI, C., BOGGI, U., CAMPANI, D., DEL CHIARO, M., et al. (2006). Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine. Cancer Res. 66, 3928-3935.
-
(2006)
Cancer Res
, vol.66
, pp. 3928-3935
-
-
Giovannetti, E.1
Del Tacca, M.2
Mey, V.3
Funel, N.4
Nannizzi, S.5
Ricci, S.6
Orlandini, C.7
Boggi, U.8
Campani, D.9
Del Chiaro, M.10
-
17
-
-
77950517325
-
The safety and side effects of monoclonal antibodies
-
HANSEL, T.T., KROPSHOFER, H., SINGER, T., MITCHELL, J.A., and GEORGE, A.J. (2010). The safety and side effects of monoclonal antibodies. Nat. Rev. Drug Disc. 9, 325-338.
-
(2010)
Nat. Rev. Drug Disc
, vol.9
, pp. 325-338
-
-
Hansel, T.T.1
Kropshofer, H.2
Singer, T.3
Mitchell, J.A.4
George, A.J.5
-
18
-
-
0000287564
-
Synthesis and Separation of Diastereomers of Ribonucleoside 5'-(α-P-Borano)triphosphates
-
HE, K., HASAN, A., KRZYZANOWSKA, B., and SHAW, B.R. (1998). Synthesis and separation of diastereomers of ribonucleoside 5¢-(alpha-P-borano) triphosphates. J. Org. Chem. 63, 5769-5773. (Pubitemid 128491742)
-
(1998)
Journal of Organic Chemistry
, vol.63
, Issue.17
, pp. 5769-5773
-
-
He, K.1
Hasan, A.2
Krzyzanowska, B.3
Shaw, B.R.4
-
19
-
-
0026324313
-
Action of 2¢,2¢-difluorodeoxycytidine on DNA synthesis
-
HUANG, P., CHUBB, S., HERTEL, L.W., GRINDEY, G.B., and PLUNKETT, W. (1991). Action of 2¢,2¢-difluorodeoxycytidine on DNA synthesis. Cancer Res. 51, 6110-6117.
-
(1991)
Cancer Res
, vol.51
, pp. 6110-6117
-
-
Huang, P.1
Chubb, S.2
Hertel, L.W.3
Grindey, G.B.4
Plunkett, W.5
-
20
-
-
32944478346
-
Phase II trial of bevacizumab plus gemcitabine in patients with advanced pancreatic cancer
-
DOI 10.1200/JCO.2005.01.9661
-
KINDLER, H.L., FRIBERG, G., SINGH, D.A., LOCKER, G., NATTAM, S., KOZLOFF, M., TABER, D.A., KARRISON, T., DACHMAN, A., STADLER, W.M., et al. (2005). Phase II trial of bevacizumab plus gemcitabine in patients with advanced pancreatic cancer. J. Clin. Oncol. 23, 8033-8040. (Pubitemid 46657405)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.31
, pp. 8033-8040
-
-
Kindler, H.L.1
Friberg, G.2
Singh, D.A.3
Locker, G.4
Nattam, S.5
Kozloff, M.6
Taber, D.A.7
Karrison, T.8
Dachman, A.9
Stadler, W.M.10
Vokes, E.E.11
-
21
-
-
44449151243
-
In vitro selection using modified or unnatural nucleotides
-
Chapter 9, Unit 9.6
-
KNUDSEN, S.M., ROBERTSON, M.P., and ELLINGTON, A.D. (2002). In vitro selection using modified or unnatural nucleotides. Curr. Protoc. Nucleic Acid Chem. Chapter 9, Unit 9.6.
-
(2002)
Curr. Protoc. Nucleic Acid Chem
-
-
Knudsen, S.M.1
Robertson, M.P.2
Ellington, A.D.3
-
22
-
-
0002831066
-
Pretreatment deoxycytidine kinase levels predict in vivo gemcitabine sensitivity
-
KROEP, J.R., LOVES, W.J., VAN DER WILT, C.L., ALVAREZ, E., TALIANIDIS, I., BOVEN, E., BRAAKHUIS, B.J., VAN GROENINGEN, C.J., PINEDO, H.M., and PETERS, G.J. (2002). Pretreatment deoxycytidine kinase levels predict in vivo gemcitabine sensitivity. Mol. Cancer Ther. 1, 371-376.
-
(2002)
Mol. Cancer Ther
, vol.1
, pp. 371-376
-
-
Kroep, J.R.1
Loves, W.J.2
Van Der Wilt, C.L.3
Alvarez, E.4
Talianidis, I.5
Boven, E.6
Braakhuis, B.J.7
Van Groeningen, C.J.8
Pinedo, H.M.9
Peters, G.J.10
-
23
-
-
47049115502
-
Nanotechnology and aptamers: Applications in drug delivery
-
LEVY-NISSENBAUM, E., RADOVIC-MORENO, A.F., WANG, A.Z., LANGER, R., and FAROKHZAD, O.C. (2008). Nanotechnology and aptamers: applications in drug delivery. Trends Biotechnol. 26, 442-449.
-
(2008)
Trends Biotechnol
, vol.26
, pp. 442-449
-
-
Levy-Nissenbaum, E.1
Radovic-Moreno, A.F.2
Wang, A.Z.3
Langer, R.4
Farokhzad, O.C.5
-
24
-
-
75649151999
-
Directed evolution of gold nanoparticle delivery to cells
-
LI, N., LARSON, T., NGUYEN, H.H., SOKOLOV, K.V., and ELLINGTON, A.D. (2010). Directed evolution of gold nanoparticle delivery to cells. Chemical communications 46, 392-394.
-
(2010)
Chemical Communications
, vol.46
, pp. 392-394
-
-
L, I.N.1
Larson, T.2
Nguyen, H.H.3
Sokolov, K.V.4
Ellington, A.D.5
-
25
-
-
79958158761
-
Inhibition of cell proliferation by an anti-EGFR aptamer
-
LI, N., NGUYEN, H.H., BYROM, M., and ELLINGTON, A.D. (2011). Inhibition of cell proliferation by an anti-EGFR aptamer. PLoS One 6, e20299.
-
(2011)
PLoS One
, vol.6
-
-
L, I.N.1
Nguyen, H.H.2
Byrom, M.3
Ellington, A.D.4
-
26
-
-
0024589767
-
Rapid and efficient synthesis of nucleoside 5'-O-(1-thiotriphosphates), 5'-triphosphates and 2',3'-cyclophosphorothioates using 2-chloro-4H-1,3,2- benzodioxaphosphorin-4-one
-
DOI 10.1021/jo00264a024
-
LUDWIG, J., and ECKSTEIN, F. (1989). Rapid and efficient synthesis of nucleoside 5¢-O-(1-thiotriphosphate)s, 5¢-triphosphates and 2¢,3¢-cyclophosphorothioates using 2-chloro-4H-1,3,2- benzodioxaphosphorin-4-one. J. Org. Chem. 54, 631-635. (Pubitemid 19060209)
-
(1989)
Journal of Organic Chemistry
, vol.54
, Issue.3
, pp. 631-635
-
-
Ludwig, J.1
Eckstein, F.2
-
27
-
-
0032188825
-
Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines
-
MACKEY, J.R., MANI, R.S., SELNER, M., MOWLES, D., YOUNG, J.D., BELT, J.A., CRAWFORD, C.R., and CASS, C.E. (1998). Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines. Cancer Res. 58, 4349-4357. (Pubitemid 28450036)
-
(1998)
Cancer Research
, vol.58
, Issue.19
, pp. 4349-4357
-
-
Mackey, J.R.1
Mani, R.S.2
Selner, M.3
Mowles, D.4
Young, J.D.5
Belt, J.A.6
Crawford, C.R.7
Cass, C.E.8
-
28
-
-
33747031960
-
Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras
-
DOI 10.1038/nbt1223, PII NBT1223
-
MCNAMARA, J.O., 2ND, ANDRECHEK, E.R., WANG, Y., VILES, K.D., REMPEL, R.E., GILBOA, E., SULLENGER, B.A., and GIANGRANDE, P.H. (2006). Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras. Nat. Biotechnol. 24, 1005-1015. (Pubitemid 44215395)
-
(2006)
Nature Biotechnology
, vol.24
, Issue.8
, pp. 1005-1015
-
-
McNamara II, J.O.1
Andrechek, E.R.2
Wang, Y.3
Viles, K.D.4
Rempel, R.E.5
Gilboa, E.6
Sullenger, B.A.7
Giangrande, P.H.8
-
29
-
-
0023651444
-
Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates
-
MILLIGAN, J.F., GROEBE, D.R., WITHERELL, G.W., and UHLENBECK, O.C. (1987). Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates. Nucleic Acids Res. 15, 8783-8798.
-
(1987)
Nucleic Acids Res
, vol.15
, pp. 8783-8798
-
-
Milligan, J.F.1
Groebe, D.R.2
Witherell, G.W.3
Uhlenbeck, O.C.4
-
30
-
-
34249933404
-
Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group
-
DOI 10.1200/JCO.2006.07.9525
-
MOORE, M.J., GOLDSTEIN, D., HAMM, J., FIGER, A., HECHT, J.R., GALLINGER, S., AU, H.J., MURAWA, P., WALDE, D., WOLFF, R.A., et al. (2007). Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J. Clin. Oncol. 25, 1960-1966. (Pubitemid 46972777)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.15
, pp. 1960-1966
-
-
Moore, M.J.1
Goldstein, D.2
Hamm, J.3
Figer, A.4
Hecht, J.R.5
Gallinger, S.6
Au, H.J.7
Murawa, P.8
Walde, D.9
Wolff, R.A.10
Campos, D.11
Lim, R.12
Ding, K.13
Clark, G.14
Voskoglou-Nomikos, T.15
Ptasynski, M.16
Parulekar, W.17
-
31
-
-
33846816556
-
Gemcitabine chemoresistance and molecular markers associated with gemcitabine transport and metabolism in human pancreatic cancer cells
-
DOI 10.1038/sj.bjc.6603559, PII 6603559
-
NAKANO, Y., TANNO, S., KOIZUMI, K., NISHIKAWA, T., NAKAMURA, K., MINOGUCHI, M., IZAWA, T., MIZUKAMI, Y., OKUMURA, T., and KOHGO, Y. (2007). Gemcitabine chemoresistance and molecular markers associated with gemcitabine transport and metabolism in human pancreatic cancer cells. Br. J. Cancer 96, 457-463. (Pubitemid 46215217)
-
(2007)
British Journal of Cancer
, vol.96
, Issue.3
, pp. 457-463
-
-
Nakano, Y.1
Tanno, S.2
Koizumi, K.3
Nishikawa, T.4
Nakamura, K.5
Minoguchi, M.6
Izawa, T.7
Mizukami, Y.8
Okumura, T.9
Kohgo, Y.10
-
32
-
-
33846405332
-
Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: A randomized controlled trial
-
DOI 10.1001/jama.297.3.267
-
OETTLE, H., POST, S., NEUHAUS, P., GELLERT, K., LANGREHR, J., RIDWELSKI, K., SCHRAMM, H., FAHLKE, J., ZUELKE, C., BURKART, C., et al. (2007). Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: a randomized controlled trial. Jama 297, 267-277. (Pubitemid 46143304)
-
(2007)
Journal of the American Medical Association
, vol.297
, Issue.3
, pp. 267-277
-
-
Oettle, H.1
Post, S.2
Neuhaus, P.3
Gellert, K.4
Langrehr, J.5
Ridwelski, K.6
Schramm, H.7
Fahlke, J.8
Zuelke, C.9
Burkart, C.10
Gutberlet, K.11
Kettner, E.12
Schmalenberg, H.13
Weigang-Koehler, K.14
Bechstein, W.-O.15
Niedergethmann, M.16
Schmidt-Wolf, I.17
Roll, L.18
Doerken, B.19
Riess, H.20
more..
-
33
-
-
67149143399
-
Inhibition of hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
-
OLIVE, K.P., JACOBETZ, M.A., DAVIDSON, C.J., GOPINATHAN, A., MCINTYRE, D., HONESS, D., MADHU, B., GOLDGRABEN, M.A., CALDWELL, M.E., ALLARD, D., et al. (2009). Inhibition of hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. Science 324, 1457-1461.
-
(2009)
Science
, vol.324
, pp. 1457-1461
-
-
Olive, K.P.1
Jacobetz, M.A.2
Davidson, C.J.3
Gopinathan, A.4
McIntyre, D.5
Honess, D.6
Madhu, B.7
Goldgraben, M.A.8
Caldwell, M.E.9
Allard, D.10
-
34
-
-
0033559119
-
Efficient synthesis of nucleic acids heavily modified with non-canonical ribose 2'-groups using a mutant T7 RNA polymerase (RNAP)
-
DOI 10.1093/nar/27.6.1561
-
PADILLA, R., and SOUSA, R. (1999). Efficient synthesis of nucleic acids heavily modified with non-canonical ribose 2¢-groups using a mutantT7 RNA polymerase (RNAP). Nucleic Acids Res. 27, 1561-1563. (Pubitemid 29206303)
-
(1999)
Nucleic Acids Research
, vol.27
, Issue.6
, pp. 1561-1563
-
-
Padilla, R.1
Sousa, R.2
-
35
-
-
40949151239
-
Targeted delivery of gemcitabine to pancreatic adenocarcinoma using cetuximab as a targeting agent
-
DOI 10.1158/0008-5472.CAN-07-6102
-
PATRA, C.R., BHATTACHARYA, R., WANG, E., KATARYA, A., LAU, J.S., DUTTA, S., MUDERS, M., WANG, S., BUHROW, S.A., SAFGREN, S.L., et al. (2008). Targeted delivery of gemcitabine to pancreatic adenocarcinoma using cetuximab as a targeting agent. Cancer Res. 68, 1970-1978. (Pubitemid 351416584)
-
(2008)
Cancer Research
, vol.68
, Issue.6
, pp. 1970-1978
-
-
Patra, C.R.1
Bhattacharya, R.2
Wang, E.3
Katarya, A.4
Lau, J.S.5
Dutta, S.6
Muders, M.7
Wang, S.8
Buhrow, S.A.9
Safgren, S.L.10
Yaszemski, M.J.11
Reid, J.M.12
Ames, M.M.13
Mukherjee, P.14
Mukhopadhyay, D.15
-
36
-
-
36549083856
-
Phase III study of gemcitabine plus cetuximab versus gemcitabine in patients with locally advanced or metastatic pancreatic adenocarcinoma: SWOG S0205 study
-
PHILIP, P., BENEDETTI, J., FENOGIO-PREISER, C., ZALUPSKI, M., LENZ, H., O'REILLY, E., WONG, R., ATKINS, J., ABBRUZZESE, J., and BLANKE, C. (2007). Phase III study of gemcitabine plus cetuximab versus gemcitabine in patients with locally advanced or metastatic pancreatic adenocarcinoma: SWOG S0205 study. J. Clin. Oncol. 25, LBA4509.
-
(2007)
J. Clin. Oncol
, vol.25
-
-
Philip, P.1
Benedetti, J.2
Fenogio-Preiser, C.3
Zalupski, M.4
Lenz, H.5
O'Reilly, E.6
Wong, R.7
Atkins, J.8
Abbruzzese, J.9
Blanke, C.10
-
37
-
-
34447299692
-
EGFR targeting of solid tumors
-
ROCHA-LIMA, C.M., SOARES, H.P., RAEZ, L.E., and SINGAL, R. (2007). EGFR targeting of solid tumors. Cancer Control 14, 295-304. (Pubitemid 47057800)
-
(2007)
Cancer Control
, vol.14
, Issue.3
, pp. 295-304
-
-
Rocha-Lima, C.M.1
Soares, H.P.2
Raez, L.E.3
Singal, R.4
-
38
-
-
0027180521
-
2',2'-difluoro-deoxycytidine (gemcitabine) incorporation into RNA and DNA of tumour cell lines
-
DOI 10.1016/0006-2952(93)90566-F
-
RUIZ VAN HAPEREN, V.W., VEERMAN, G., VERMORKEN, J.B., and PETERS, G.J. (1993). 2¢,2¢-Difluoro-deoxycytidine (gemcitabine) incorporation into RNA and DNA of tumour cell lines. Biochem. Pharmacol. 46, 762-766. (Pubitemid 23262974)
-
(1993)
Biochemical Pharmacology
, vol.46
, Issue.4
, pp. 762-766
-
-
Ruiz Van Haperen, V.W.T.1
Veerman, G.2
Vermorken, J.B.3
Peters, G.J.4
-
39
-
-
80051580618
-
Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths
-
SIEGEL, R., WARD, E., BRAWLEY, O., and JEMAL, A. (2011). Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J. Clin. 61, 212-236.
-
(2011)
CA Cancer J. Clin
, vol.61
, pp. 212-236
-
-
Siegel, R.1
Ward, E.2
Brawley, O.3
Jemal, A.4
-
40
-
-
70350438402
-
Plasma membrane nucleolin is a receptor for the anticancer aptamer AS1411 in MV4-11 leukemia cells
-
SOUNDARARAJAN, S., WANG, L., SRIDHARAN, V., CHEN, W., COURTENAY-LUCK, N., JONES, D., SPICER, E.K., and FERNANDES, D.J. (2009). Plasma membrane nucleolin is a receptor for the anticancer aptamer AS1411 in MV4-11 leukemia cells. Mol. Pharmacol. 76, 984-991.
-
(2009)
Mol. Pharmacol
, vol.76
, pp. 984-991
-
-
Soundararajan, S.1
Wang, L.2
Sridharan, V.3
Chen, W.4
Courtenay-Luck, N.5
Jones, D.6
Spicer, E.K.7
Fernandes, D.J.8
-
41
-
-
0029091457
-
A mutant T7 RNA polymerase as a DNA polymerase
-
SOUSA, R., and PADILLA, R. (1995). A mutant T7 RNA polymerase as a DNA polymerase. EMBO 14, 4609-4621.
-
(1995)
EMBO
, vol.14
, pp. 4609-4621
-
-
Sousa, R.1
Padilla, R.2
-
42
-
-
0025194307
-
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
-
TUERK, C., and GOLD, L. (1990). Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 249, 505-510.
-
(1990)
Science
, vol.249
, pp. 505-510
-
-
Tuerk, C.1
Gold, L.2
-
43
-
-
0025343230
-
Signal transduction by receptors with tyrosine kinase activity
-
ULLRICH, A., and SCHLESSINGER, J. (1990). Signal transduction by receptors with tyrosine kinase activity. Cell 61, 203-212.
-
(1990)
Cell
, vol.61
, pp. 203-212
-
-
Ullrich, A.1
Schlessinger, J.2
-
44
-
-
0030461226
-
Control of EGF receptor signaling by clathrin-mediated endocytosis
-
DOI 10.1126/science.274.5295.2086
-
VIEIRA, A.V., LAMAZE, C., and SCHMID, S.L. (1996). Control of EGF receptor signaling by clathrin-mediated endocytosis. Science 274, 2086-2089. (Pubitemid 27020702)
-
(1996)
Science
, vol.274
, Issue.5295
, pp. 2086-2089
-
-
Vieira, A.V.1
Lamaze, C.2
Schmid, S.L.3
-
45
-
-
0022780091
-
Oligodeoxynucleotide stability in subcellular extracts and culture media
-
WICKSTROM, E. (1986). Oligodeoxynucleotide stability in subcellular extracts and culture media. J. Biochem. Biophys. Methods 13, 97-102.
-
(1986)
J. Biochem. Biophys. Methods
, vol.13
, pp. 97-102
-
-
Wickstrom, E.1
-
46
-
-
4344590997
-
Cetuximab, a monoclonal antibody targeting the epidermal growth factor receptor, in combination with gemcitabine for advanced pancreatic cancer: A multicenter phase II trial
-
DOI 10.1200/JCO.2004.12.040
-
XIONG, H.Q., ROSENBERG, A., LOBUGLIO, A., SCHMIDT, W., WOLFF, R.A., DEUTSCH, J., NEEDLE, M., and ABBRUZZESE, J.L. (2004). Cetuximab, a monoclonal antibody targeting the epidermal growth factor receptor, in combination with gemcitabine for advanced pancreatic cancer: a multicenter phase II trial. J. Clin. Oncol. 22, 2610-2616. (Pubitemid 41103748)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.13
, pp. 2610-2616
-
-
Xiong, H.Q.1
Rosenberg, A.2
LoBuglio, A.3
Schmidt, W.4
Wolff, R.A.5
Deutsch, J.6
Needle, M.7
Abbruzzese, J.L.8
-
47
-
-
79952529043
-
Aptamers selected by cell-SELEX for application in cancer studies
-
ZHANG, Y., CHEN, Y., HAN, D., OCSOY, I., and TAN, W. (2010). Aptamers selected by cell-SELEX for application in cancer studies. Bioanalysis 2, 907-918.
-
(2010)
Bioanalysis
, vol.2
, pp. 907-918
-
-
Zhang, Y.1
Chen, Y.2
Han, D.3
Ocsoy, I.4
Tan, W.5
-
48
-
-
79951818184
-
Cell-specific aptamer-mediated targeted drug delivery
-
ZHOU, J., and ROSSI, J.J. (2011). Cell-specific aptamer-mediated targeted drug delivery. Oligonucleotides 21, 1-10.
-
(2011)
Oligonucleotides
, vol.21
, pp. 1-10
-
-
Zhou, J.1
Rossi, J.J.2
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