PI3K/Akt-dependent phosphorylation of GSK3β and activation of RhoA regulate Wnt5a-induced gastric cancer cell migration

Cellular Signalling

Volumn 25, Issue 2, 2013, Pages 447-456

  Liu, Jiaojing ^a   Zhang, Yujie ^a   Xu, Rui ^a   Du, Jun ^a   Hu, Zhenzhen ^a   Yang, Ling ^b   Chen, Yongchang ^c   Zhu, Yichao ^a   Gu, Luo ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b THE THIRD AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^c JIANGSU UNIVERSITY   (China)

Author keywords

Gastric cancer; GSK3 ; Migration; PI3K Akt; RhoA; Wnt5a

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; GLYCOGEN SYNTHASE KINASE 3BETA; LITHIUM CHLORIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SERINE; SMALL INTERFERING RNA; WNT5A PROTEIN;

ARTICLE; CANCER CELL; CANCER INHIBITION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STOMACH CANCER; STOMACH CARCINOGENESIS; STRESS FIBER;

CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL MOVEMENT; CHROMONES; ENZYME ACTIVATION; GLYCOGEN SYNTHASE KINASE 3; HUMANS; LITHIUM CHLORIDE; MORPHOLINES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT PROTEINS; RHOA GTP-BINDING PROTEIN; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; WNT PROTEINS;

EID: 84870351089     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2012.10.012     Document Type: Article

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