Screening approach, optimisation and scale-up for chiral liquid chromatography of cathinones

Journal of Chromatography A

Volumn 1269, Issue , 2012, Pages 189-197

  Perera, R Wimal H ^a   Abraham, Ijeoma ^a   Gupta, Shradha ^a   Kowalska, Patrycja ^a   Lightsey, Danielle ^a   Marathaki, Chrysoula ^a   Singh, Nagendra S ^a   Lough, W John ^a  

^a UNIVERSITY OF SUNDERLAND   (United Kingdom)

Author keywords

Cathinones; Chiral LC screening; Optimisation; RegisCell; Scale up; Whelk O1

Indexed keywords

CATHINONES; CHIRAL LC; OPTIMISATIONS; REGISCELL; SCALE-UP; WHELK-O1;

CHIRALITY; ENANTIOSELECTIVITY; HEXANE; LIQUID CHROMATOGRAPHY; OPTIMIZATION; SEPARATION;

SHELLFISH;

2 PROPANOL; 4' METHYLMETHCATHINONE; CATHINONE; HEXANE; SOLVENT; TRIETHYLAMINE; TRIFLUOROACETIC ACID;

ANALYTIC METHOD; ARTICLE; CHEMICAL STRUCTURE; CHIRALITY; CONTROLLED STUDY; ENANTIOSELECTIVITY; LIQUID CHROMATOGRAPHY; PHASE SEPARATION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SCALE UP; SCREENING TEST; SEPARATION TECHNIQUE;

ALKALOIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; SPECTROPHOTOMETRY, ULTRAVIOLET; STEREOISOMERISM;

EID: 84870338541     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2012.11.001     Document Type: Article

References (26)

1. Wainer I.W. Trends Anal. Chem. 1987, 6(5):125.
2. Anderson M.E., Aslan D., Clarke A., et al. J. Chromatogr. A 2003, 1005:1.
3. Dossou K.S.S., Chiap P., Chankyetadze B., et al. J. Sep. Sci. 2010, 33(12):1699.
4. Peng L., Farkas T., Jayapaian S., et al. Chromatogr. Today 2009, 2(3):26.
5. Younes A.A., Managelings D., Heyden Y.V. J. Pharm. Biomed. Anal. 2011, 55(3):414.
6. Younes A.A., Managelings D., Heyden Y.V. J. Pharm. Biomed. Anal. 2011, 56(3):521.
7. Bracci P. Mephedrone Menace: The Deadly Drug that's Cheap, Easy to Order as Pizza... and Totally Legal 2009, Daily Mail, (accessed on February 2010). http://www.dailymail.co.uk/news/article-1231538/Mephedrone-menace-The-deadly-drug-thats-cheap-order-pizza-totally-legal.html.
8. Daily Mail Action Pledged on 'Meow, Meow' Drug After Two Teen Friends Die within Hours of Taking 'Legal High' 2010, (accessed on 21.03.10). http://www.dailymail.co.uk/news/article-1258384/Schools-mephedrone-Meow-Meow-ban-teenage-deaths.html.
9. Torrance H., Cooper G. Forensic Sci. Int. 2010, 202:e62.
10. N. Garnet, Mephedrone freely available on the internet despite ban, BBC Radio 5 live last updated 8 February 2011 at 08.51, 2011, http://www.bbc.co.uk/news/uk-12389321.
11. De Paoli G., Maskell P.D., Pounder D.J. J. Forensic Legal Med. 2011, 18:93.
12. Abdel-Hay K.M., Awad T., DeRuiter J., et al. Forensic Sci. Int. 2010, 195:78.
13. Chappel J.S., Lee M.M. Forensic Sci. Int. 2010, 195:108.
14. Ariëns E.J. Eur. J. Clin. Pharmacol. 1984, 26:663.
15. Maickel R.P., Light K.E., Zabic J.E. Neuropharmacology 1982, 21(12):1323.
16. Plotka J.M., Morrison C., Biziuk M. Trends Anal. Chem. 2011, 30(7):1139.
17. Raihana W.A., Gan S.H., Tan S.C. J. Chromatogr. A 2011, 879(1):8.
18. Miller K.J., Gal J., Ames M.M. J. Chromatogr. 1984, 307:335.
19. Bagnall J.P., Evans S.E., Wort M.T., et al. J. Chromatogr. A 2012, 1249:115.
20. Benshafrut R., Rothchild R. Spectrosc. Lett. 1992, 25(7):1097.
21. Hyun M.H., Tan G.H., Cho Y.J. J. Liq. Chromatogr. Relat. Technol. 2004, 27(11):1671.
22. Riley C.J. HPLC. Fundamental Principles and Practices 1989, 15. Blackie and Son Ltd., Glasgow. W.J. Lough, I.W. Wainer (Eds.).
23. Perera R.W.H., Lough W.J. J. Chromatogr. A 2011, 1218(48):8655.
24. Cox G.B. Drug Stereochemistry: Analytical Methods and Pharmacology 2012, 113. Informa Healthcare, London. 3rd ed. K. Jozwiak, W.J. Lough, I.W. Wainer (Eds.).
25. L. Yuan, (accessed on 02.10.12). http://www.thairohs.org/index.php%3Foption=com_docman%26task=doc_view%26gid=70.
26. Mohr S., Taschwer M., Schmid M.G. Chirality 2012, 24(6):486.