메뉴 건너뛰기




Volumn 26, Issue 12, 2012, Pages 4855-4863

Bone structure and B-cell populations, crippled by obesity, are partially rescued by brief daily exposure to low-magnitude mechanical signals

Author keywords

Adiposity; Diabetes

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; OSTEOCLAST DIFFERENTIATION FACTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR PAX5;

EID: 84870329227     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.12-209841     Document Type: Article
Times cited : (56)

References (57)
  • 2
    • 77950650638 scopus 로고    scopus 로고
    • Diet-induced obesity alters bone remodeling leading to decreased femoral trabecular bone mass in mice
    • Cao, J. J., Sun, L., and Gao, H. (2010) Diet-induced obesity alters bone remodeling leading to decreased femoral trabecular bone mass in mice. Ann. N. Y. Acad. Sci. 1192, 292-297
    • (2010) Ann. N. Y. Acad. Sci. , vol.1192 , pp. 292-297
    • Cao, J.J.1    Sun, L.2    Gao, H.3
  • 4
    • 78649828932 scopus 로고    scopus 로고
    • Obesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in mice
    • Halade, G. V., El Jamali, A., Williams, P. J., Fajardo, R. J., and Fernandes, G. (2011) Obesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in mice. Exp. Gerontol. 46, 43-52
    • (2011) Exp. Gerontol. , vol.46 , pp. 43-52
    • Halade, G.V.1    El Jamali, A.2    Williams, P.J.3    Fajardo, R.J.4    Fernandes, G.5
  • 5
    • 78249259079 scopus 로고    scopus 로고
    • High fat diet-induced animal model of age-associated obesity and osteoporosis
    • Halade, G. V., Rahman, M. M., Williams, P. J., and Fernandes, G. (2010) High fat diet-induced animal model of age-associated obesity and osteoporosis. J. Nutr. Biochem. 21, 1162-1169
    • (2010) J. Nutr. Biochem. , vol.21 , pp. 1162-1169
    • Halade, G.V.1    Rahman, M.M.2    Williams, P.J.3    Fernandes, G.4
  • 8
    • 64349090658 scopus 로고    scopus 로고
    • Bone, fat, and body composition: Evolving concepts in the pathogenesis of osteoporosis
    • Rosen, C. J., and Klibanski, A. (2009) Bone, fat, and body composition: evolving concepts in the pathogenesis of osteoporosis. Am. J. Med. 122, 409-414
    • (2009) Am. J. Med. , vol.122 , pp. 409-414
    • Rosen, C.J.1    Klibanski, A.2
  • 10
    • 28544431852 scopus 로고    scopus 로고
    • Alterations in T-cell subset frequency in peripheral blood in obesity
    • DOI 10.1381/096089205774859308
    • O'Rourke, R. W., Kay, T., Scholz, M. H., Diggs, B., Jobe, B. A., Lewinsohn, D. M., and Bakke, A. C. (2005) Alterations in T-cell subset frequency in peripheral blood in obesity. Obes. Surg. 15, 1463-1468 (Pubitemid 41746423)
    • (2005) Obesity Surgery , vol.15 , Issue.10 , pp. 1463-1468
    • O'Rourke, R.W.1    Kay, T.2    Scholz, M.H.3    Diggs, B.4    Jobe, B.A.5    Lewinsohn, D.M.6    Bakke, A.C.7
  • 11
    • 70349303404 scopus 로고    scopus 로고
    • Long term effects of high fat and sucrose diets on obesity and lymphocyte proliferation in mice
    • Sato Mito, N., Suzui, M., Yoshino, H., Kaburagi, T., and Sato, K. (2009) Long term effects of high fat and sucrose diets on obesity and lymphocyte proliferation in mice. J. Nutr. Health Aging 13, 602-606
    • (2009) J. Nutr. Health Aging , vol.13 , pp. 602-606
    • Sato Mito, N.1    Suzui, M.2    Yoshino, H.3    Kaburagi, T.4    Sato, K.5
  • 12
    • 33947583822 scopus 로고    scopus 로고
    • Osteoimmunology: Shared mechanisms and crosstalk between the immune and bone systems
    • Takayanagi, H. (2007) Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems. Nat. Rev. Immunol. 7, 292-304
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 292-304
    • Takayanagi, H.1
  • 13
    • 34548648830 scopus 로고    scopus 로고
    • Ten months of exercise improves general and visceral adiposity, bone, and fitness in black girls
    • Barbeau, P., Johnson, M. H., Howe, C. A., Allison, J., Davis, C. L., Gutin, B., and Lemmon, C. R. (2007) Ten months of exercise improves general and visceral adiposity, bone, and fitness in black girls. Obesity 15, 2077-2085 (Pubitemid 47402240)
    • (2007) Obesity , vol.15 , Issue.8 , pp. 2077-2085
    • Barbeau, P.1    Johnson, M.H.2    Howe, C.A.3    Allison, J.4    Davis, C.L.5    Gutin, B.6    Lemmon, C.R.7
  • 14
    • 53849106784 scopus 로고    scopus 로고
    • Child obesity can be reduced with vigorous activity rather than restriction of energy intake
    • Gutin, B. (2008) Child obesity can be reduced with vigorous activity rather than restriction of energy intake. Obesity 16, 2193-2196
    • (2008) Obesity , vol.16 , pp. 2193-2196
    • Gutin, B.1
  • 15
    • 0025750835 scopus 로고
    • Prevention of type 2 (non-insulin-dependent) diabetes mellitus by diet and physical exercise. The 6-year Malmo feasibility study
    • Eriksson, K. F., and Lindgarde, F. (1991) Prevention of type 2 (non-insulin-dependent) diabetes mellitus by diet and physical exercise. The 6-year Malmo feasibility study. Diabetologia 34, 891-898
    • (1991) Diabetologia , vol.34 , pp. 891-898
    • Eriksson, K.F.1    Lindgarde, F.2
  • 16
    • 0029248143 scopus 로고
    • Effect of dietary and/or exercise intervention on incidence of diabetes in 530 subjects with impaired glucose tolerance (from 1986-1992)
    • Pan, X., Li, G., and Hu, Y. (1995) [Effect of dietary and/or exercise intervention on incidence of diabetes in 530 subjects with impaired glucose tolerance (from 1986-1992)]. Zhonghua Nei Ke Za Zhi 34, 108-112
    • (1995) Zhonghua Nei Ke Za Zhi , vol.34 , pp. 108-112
    • Pan, X.1    Li, G.2    Hu, Y.3
  • 17
    • 0024948991 scopus 로고
    • The role of physical exercise in prevention and management of osteoporosis
    • Dilsen, G., Berker, C., Oral, A., and Varan, G. (1989) The role of physical exercise in prevention and management of osteoporosis. Clin. Rheumatol. 8(Suppl. 2), 70-75 (Pubitemid 20122984)
    • (1989) Clinical Rheumatology , vol.8 , Issue.SUPPL. 2 , pp. 70-75
    • Dilsen, G.1    Berker, C.2    Oral, A.3    Varan, G.4
  • 18
    • 78049271882 scopus 로고    scopus 로고
    • The effect of a multicomponent dual-modality exercise program targeting osteoporosis on bone health status and physical function capacity of postmenopausal women
    • Tolomio, S., Ermolao, A., Lalli, A., and Zaccaria, M. (2010) The effect of a multicomponent dual-modality exercise program targeting osteoporosis on bone health status and physical function capacity of postmenopausal women. J. Women Aging 22, 241-254
    • (2010) J. Women Aging , vol.22 , pp. 241-254
    • Tolomio, S.1    Ermolao, A.2    Lalli, A.3    Zaccaria, M.4
  • 19
    • 79952598936 scopus 로고    scopus 로고
    • Signaling mechanisms in the restoration of impaired immune function due to diet-induced obesity
    • Zhou, Q., Leeman, S. E., and Amar, S. (2011) Signaling mechanisms in the restoration of impaired immune function due to diet-induced obesity. Proc. Natl. Acad. Sci. U. S. A. 108, 2867-2872
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 2867-2872
    • Zhou, Q.1    Leeman, S.E.2    Amar, S.3
  • 21
    • 76749108869 scopus 로고    scopus 로고
    • Development of diet-induced fatty liver disease in the aging mouse is suppressed by brief daily exposure to low-magnitude mechanical signals
    • Luu, Y. K., Ozcivici, E., Capilla, E., Adler, B., Chan, E., Shroyer, K., Rubin, J., Judex, S., Pessin, J. E., and Rubin, C. T. (2010) Development of diet-induced fatty liver disease in the aging mouse is suppressed by brief daily exposure to low-magnitude mechanical signals. Int. J. Obes. (Lond.) 34, 401-405
    • (2010) Int. J. Obes. (Lond.) , vol.34 , pp. 401-405
    • Luu, Y.K.1    Ozcivici, E.2    Capilla, E.3    Adler, B.4    Chan, E.5    Shroyer, K.6    Rubin, J.7    Judex, S.8    Pessin, J.E.9    Rubin, C.T.10
  • 23
    • 33947606818 scopus 로고    scopus 로고
    • Low-magnitude mechanical signals that stimulate bone formation in the ovariectomized rat are dependent on the applied frequency but not on the strain magnitude
    • DOI 10.1016/j.jbiomech.2006.05.014, PII S0021929006001680
    • Judex, S., Lei, X., Han, D., and Rubin, C. (2007) Low-magnitude mechanical signals that stimulate bone formation in the ovariectomized rat are dependent on the applied frequency but not on the strain magnitude. J. Biomech. 40, 1333-1339 (Pubitemid 46483448)
    • (2007) Journal of Biomechanics , vol.40 , Issue.6 , pp. 1333-1339
    • Judex, S.1    Lei, X.2    Han, D.3    Rubin, C.4
  • 24
    • 58149084456 scopus 로고    scopus 로고
    • Mechanical stimulation of mesenchymal stem cell proliferation and differentiation promotes osteogenesis while preventing dietary-induced obesity
    • Luu, Y. K., Capilla, E., Rosen, C. J., Gilsanz, V., Pessin, J. E., Judex, S., and Rubin, C. T. (2009) Mechanical stimulation of mesenchymal stem cell proliferation and differentiation promotes osteogenesis while preventing dietary-induced obesity. J. Bone Miner. Res. 24, 50-61
    • (2009) J. Bone Miner. Res. , vol.24 , pp. 50-61
    • Luu, Y.K.1    Capilla, E.2    Rosen, C.J.3    Gilsanz, V.4    Pessin, J.E.5    Judex, S.6    Rubin, C.T.7
  • 25
    • 77956200031 scopus 로고    scopus 로고
    • Low-level vibrations retain bone marrow's osteogenic potential and augment recovery of trabecular bone during reambulation
    • Ozcivici, E., Luu, Y. K., Rubin, C. T., and Judex, S. (2010) Low-level vibrations retain bone marrow's osteogenic potential and augment recovery of trabecular bone during reambulation. PLoS One 5, e11178
    • (2010) PLoS One , vol.5
    • Ozcivici, E.1    Luu, Y.K.2    Rubin, C.T.3    Judex, S.4
  • 26
    • 0032192369 scopus 로고    scopus 로고
    • How the osteoclast degrades bone
    • Blair, H. C. (1998) How the osteoclast degrades bone. Bioessays 20, 837-846
    • (1998) Bioessays , vol.20 , pp. 837-846
    • Blair, H.C.1
  • 27
    • 0028825896 scopus 로고
    • Human osteoclasts, not osteoblasts, deposit osteopontin onto resorption surfaces: An in vitro and ex vivo study of remodeling bone
    • Dodds, R. A., Connor, J. R., James, I. E., Rykaczewski, E. L., Appelbaum, E., Dul, E., and Gowen, M. (1995) Human osteoclasts, not osteoblasts, deposit osteopontin onto resorption surfaces: an in vitro and ex vivo study of remodeling bone. J. Bone Min. Res. 10, 1666-1680
    • (1995) J. Bone Min. Res. , vol.10 , pp. 1666-1680
    • Dodds, R.A.1    Connor, J.R.2    James, I.E.3    Rykaczewski, E.L.4    Appelbaum, E.5    Dul, E.6    Gowen, M.7
  • 28
    • 0029928698 scopus 로고    scopus 로고
    • Linkage of decreased bone mass with impaired osteoblastogenesis in a murine model of accelerated senescence
    • Jilka, R. L., Weinstein, R. S., Takahashi, K., Parfitt, A. M., and Manolagas, S. C. (1996) Linkage of decreased bone mass with impaired osteoblastogenesis in a murine model of accelerated senescence. J. Clin. Invest. 97, 1732-1740 (Pubitemid 26105482)
    • (1996) Journal of Clinical Investigation , vol.97 , Issue.7 , pp. 1732-1740
    • Jilka, R.L.1    Weinstein, R.S.2    Takahashi, K.3    Parfitt, A.M.4    Manolagas, S.C.5
  • 30
    • 67349206475 scopus 로고    scopus 로고
    • Automated separation of visceral and subcutaneous adiposity in in vivo microcomputed tomographies of mice
    • Lublinsky, S., Luu, Y. K., Rubin, C. T., and Judex, S. (2009) Automated separation of visceral and subcutaneous adiposity in in vivo microcomputed tomographies of mice. J. Digit. Imaging 22, 222-231
    • (2009) J. Digit. Imaging , vol.22 , pp. 222-231
    • Lublinsky, S.1    Luu, Y.K.2    Rubin, C.T.3    Judex, S.4
  • 31
    • 57849127155 scopus 로고    scopus 로고
    • In vivo quantification of subcutaneous and visceral adiposity by micro-computed tomography in a small animal model
    • Luu, Y. K., Lublinsky, S., Ozcivici, E., Capilla, E., Pessin, J. E., Rubin, C. T., and Judex, S. (2009) In vivo quantification of subcutaneous and visceral adiposity by micro-computed tomography in a small animal model. Med. Eng. Phys. 31, 34-41
    • (2009) Med. Eng. Phys. , vol.31 , pp. 34-41
    • Luu, Y.K.1    Lublinsky, S.2    Ozcivici, E.3    Capilla, E.4    Pessin, J.E.5    Rubin, C.T.6    Judex, S.7
  • 32
    • 34848889332 scopus 로고    scopus 로고
    • An automated algorithm to detect the trabecular-cortical bone interface in micro-computed tomographic images
    • DOI 10.1007/s00223-007-9063-8
    • Lublinsky, S., Ozcivici, E., and Judex, S. (2007) An automated algorithm to detect the trabecular-cortical bone interface in micro-computed tomographic images. Calcif. Tissue Int. 81, 285-293 (Pubitemid 47498105)
    • (2007) Calcified Tissue International , vol.81 , Issue.4 , pp. 285-293
    • Lublinsky, S.1    Ozcivici, E.2    Judex, S.3
  • 33
    • 41349087734 scopus 로고    scopus 로고
    • - side population cells represent a functionally distinct population of long-term hematopoietic stem cells
    • DOI 10.1182/blood-2007-09-115006
    • Weksberg, D. C., Chambers, S. M., Boles, N. C., and Goodell, M. A. (2008) CD150- side population cells represent a functionally distinct population of long-term hematopoietic stem cells. Blood 111, 2444-2451 (Pubitemid 351451458)
    • (2008) Blood , vol.111 , Issue.4 , pp. 2444-2451
    • Weksberg, D.C.1    Chambers, S.M.2    Boles, N.C.3    Goodell, M.A.4
  • 34
    • 0033533891 scopus 로고    scopus 로고
    • Commitment to the B-lymphoid lineage depends on the transcription factor Pax5
    • Nutt, S. L., Heavey, B., Rolink, A. G., and Busslinger, M. (1999) Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. Nature 401, 556-562
    • (1999) Nature , vol.401 , pp. 556-562
    • Nutt, S.L.1    Heavey, B.2    Rolink, A.G.3    Busslinger, M.4
  • 35
    • 0027997502 scopus 로고
    • Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP
    • DOI 10.1016/0092-8674(94)90079-5
    • Urbanek, P., Wang, Z. Q., Fetka, I., Wagner, E. F., and Busslinger, M. (1994) Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP. Cell 79, 901-912 (Pubitemid 24371980)
    • (1994) Cell , vol.79 , Issue.5 , pp. 901-912
    • Urbanek, P.1    Wang, Z.-Q.2    Fetka, I.3    Wagner, E.F.4    Busslinger, M.5
  • 36
    • 55849088412 scopus 로고    scopus 로고
    • NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism
    • Aliprantis, A. O., Ueki, Y., Sulyanto, R., Park, A., Sigrist, K. S., Sharma, S. M., Ostrowski, M. C., Olsen, B. R., and Glimcher, L. H. (2008) NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism. J. Clin. Invest. 118, 3775-3789
    • (2008) J. Clin. Invest. , vol.118 , pp. 3775-3789
    • Aliprantis, A.O.1    Ueki, Y.2    Sulyanto, R.3    Park, A.4    Sigrist, K.S.5    Sharma, S.M.6    Ostrowski, M.C.7    Olsen, B.R.8    Glimcher, L.H.9
  • 37
    • 36849034568 scopus 로고    scopus 로고
    • PPAR-gamma regulates osteoclastogenesis in mice
    • Wan, Y., Chong, L. W., and Evans, R. M. (2007) PPAR-gamma regulates osteoclastogenesis in mice. Nat. Med. 13, 1496-1503
    • (2007) Nat. Med. , vol.13 , pp. 1496-1503
    • Wan, Y.1    Chong, L.W.2    Evans, R.M.3
  • 38
    • 77956408841 scopus 로고    scopus 로고
    • PGC1beta mediates PPARgamma activation of osteoclastogenesis and rosiglitazone-induced bone loss
    • Wei, W., Wang, X., Yang, M., Smith, L. C., Dechow, P. C., Sonoda, J., Evans, R. M., and Wan, Y. (2010) PGC1beta mediates PPARgamma activation of osteoclastogenesis and rosiglitazone-induced bone loss. Cell Metab. 11, 503-516
    • (2010) Cell Metab. , vol.11 , pp. 503-516
    • Wei, W.1    Wang, X.2    Yang, M.3    Smith, L.C.4    Dechow, P.C.5    Sonoda, J.6    Evans, R.M.7    Wan, Y.8
  • 39
    • 0036405426 scopus 로고    scopus 로고
    • Osteoclasts from mice deficient in tartrate-resistant acid phosphatase have altered ruffled borders and disturbed intracellular vesicular transport
    • DOI 10.1006/excr.2002.5612
    • Hollberg, K., Hultenby, K., Hayman, A., Cox, T., and Andersson, G. (2002) Osteoclasts from mice deficient in tartrate-resistant acid phosphatase have altered ruffled borders and disturbed intracellular vesicular transport. Exp. Cell Res. 279, 227-238 (Pubitemid 35217551)
    • (2002) Experimental Cell Research , vol.279 , Issue.2 , pp. 227-238
    • Hollberg, K.1    Hultenby, K.2    Hayman, A.R.3    Cox, T.M.4    Andersson, G.5
  • 40
    • 0025117967 scopus 로고
    • Histochemistry and biochemistry of tartrate-resistant acid phosphatase (TRAP) and tartrate-resistant acid adenosine triphosphatase (TrATPase) in bone, bone marrow and spleen: Implications for osteoclast ontogeny
    • DOI 10.1016/0169-6009(90)90086-U
    • Lindunger, A., MacKay, C. A., Ek-Rylander, B., Andersson, G., and Marks, S. C., Jr. (1990) Histochemistry and biochemistry of tartrate-resistant acid phosphatase (TRAP) and tartrate-resistant acid adenosine triphosphatase (TrATPase) in bone, bone marrow and spleen: implications for osteoclast ontogeny. Bone Miner. 10, 109-119 (Pubitemid 20254670)
    • (1990) Bone and Mineral , vol.10 , Issue.2 , pp. 109-119
    • Lindunger, A.1    MacKay, C.A.2    Ek-Rylander, B.3    Andersson, G.4    Marks Jr., S.C.5
  • 41
    • 79958772773 scopus 로고    scopus 로고
    • Denosumab, a fully human RANKL antibody, reduced bone turnover markers and increased trabecular and cortical bone mass, density, and strength in ovariectomized cynomolgus monkeys
    • Ominsky, M. S., Stouch, B., Schroeder, J., Pyrah, I., Stolina, M., Smith, S. Y., and Kostenuik, P. J. (2011) Denosumab, a fully human RANKL antibody, reduced bone turnover markers and increased trabecular and cortical bone mass, density, and strength in ovariectomized cynomolgus monkeys. Bone 49, 162-173
    • (2011) Bone , vol.49 , pp. 162-173
    • Ominsky, M.S.1    Stouch, B.2    Schroeder, J.3    Pyrah, I.4    Stolina, M.5    Smith, S.Y.6    Kostenuik, P.J.7
  • 42
    • 67650503219 scopus 로고    scopus 로고
    • Regulatory mechanism of NFATc1 in RANKL-induced osteoclast activation
    • Song, I., Kim, J. H., Kim, K., Jin, H. M., Youn, B. U., and Kim, N. (2009) Regulatory mechanism of NFATc1 in RANKL-induced osteoclast activation. FEBS Lett. 583, 2435-2440
    • (2009) FEBS Lett. , vol.583 , pp. 2435-2440
    • Song, I.1    Kim, J.H.2    Kim, K.3    Jin, H.M.4    Youn, B.U.5    Kim, N.6
  • 43
    • 67349252445 scopus 로고    scopus 로고
    • High-fat diet decreases cancellous bone mass but has no effect on cortical bone mass in the tibia in mice
    • Cao, J. J., Gregoire, B. R., and Gao, H. (2009) High-fat diet decreases cancellous bone mass but has no effect on cortical bone mass in the tibia in mice. Bone 44, 1097-1104
    • (2009) Bone , vol.44 , pp. 1097-1104
    • Cao, J.J.1    Gregoire, B.R.2    Gao, H.3
  • 44
    • 79960255886 scopus 로고    scopus 로고
    • Long-term impact of overweight and obesity in childhood and adolescence on morbidity and premature mortality in adulthood: Systematic review
    • Reilly, J. J., and Kelly, J. (2011) Long-term impact of overweight and obesity in childhood and adolescence on morbidity and premature mortality in adulthood: systematic review. Int. J. Obes. (Lond.) 35, 891-898
    • (2011) Int. J. Obes. (Lond.) , vol.35 , pp. 891-898
    • Reilly, J.J.1    Kelly, J.2
  • 46
    • 34548040666 scopus 로고    scopus 로고
    • Abdominal adiposity and cardiometabolic risk: Do we have all the answers?
    • discussion S16-S17
    • Haffner, S. M. (2007) Abdominal adiposity and cardiometabolic risk: do we have all the answers? Am. J. Med. 120, S10-S16; discussion S16-S17
    • (2007) Am. J. Med. , vol.120
    • Haffner, S.M.1
  • 47
    • 0034970403 scopus 로고    scopus 로고
    • Pericardial fat accumulation in men as a risk factor for coronary artery disease
    • DOI 10.1016/S0021-9150(00)00709-7, PII S0021915000007097
    • Taguchi, R., Takasu, J., Itani, Y., Yamamoto, R., Yokoyama, K., Watanabe, S., and Masuda, Y. (2001) Pericardial fat accumulation in men as a risk factor for coronary artery disease. Atherosclerosis 157, 203-209 (Pubitemid 32539372)
    • (2001) Atherosclerosis , vol.157 , Issue.1 , pp. 203-209
    • Taguchi, R.1    Takasu, J.2    Itani, Y.3    Yamamoto, R.4    Yokoyama, K.5    Watanabe, S.6    Masuda, Y.7
  • 49
    • 77649220941 scopus 로고    scopus 로고
    • Is bone formation induced by high-frequency mechanical signals modulated by muscle activity?
    • Judex, S., and Rubin, C. T. (2010) Is bone formation induced by high-frequency mechanical signals modulated by muscle activity? J. Musculoskelet. Neuronal Interact. 10, 3-11
    • (2010) J. Musculoskelet. Neuronal Interact. , vol.10 , pp. 3-11
    • Judex, S.1    Rubin, C.T.2
  • 50
    • 0041762493 scopus 로고    scopus 로고
    • Bone development and age-related bone loss in male C57BL/6J mice
    • DOI 10.1016/S8756-3282(03)00199-6
    • Ferguson, V. L., Ayers, R. A., Bateman, T. A., and Simske, S. J. (2003) Bone development and age-related bone loss in male C57BL/6J mice. Bone 33, 387-398 (Pubitemid 37107464)
    • (2003) Bone , vol.33 , Issue.3 , pp. 387-398
    • Ferguson, V.L.1    Ayers, R.A.2    Bateman, T.A.3    Simske, S.J.4
  • 51
    • 0032956462 scopus 로고    scopus 로고
    • The effects of age and dietary restriction without nutritional supplementation on whole bone structural properties in C57BL/6J mice
    • Ferguson, V. L., Greenberg, A. R., Bateman, T. A., Ayers, R. A., and Simske, S. J. (1999) The effects of age and dietary restriction without nutritional supplementation on whole bone structural properties in C57BL/6J mice. Biomed. Sci. Instrum. 35, 85-91 (Pubitemid 29234000)
    • (1999) Biomedical Sciences Instrumentation , vol.35 , pp. 85-91
    • Ferguson, V.L.1    Greenberg, A.R.2    Bateman, T.A.3    Ayers, R.A.4    Simske, S.J.5
  • 53
    • 2942754341 scopus 로고    scopus 로고
    • Prevention of postmenopausal bone loss by a low-magnitude, high-frequency mechanical stimuli: A clinical trial assessing compliance, efficacy, and safety
    • DOI 10.1359/JBMR.0301251
    • Rubin, C., Recker, R., Cullen, D., Ryaby, J., McCabe, J., and McLeod, K. (2004) Prevention of postmenopausal bone loss by a low-magnitude, high-frequency mechanical stimuli: a clinical trial assessing compliance, efficacy, and safety. J. Bone Miner. Res. 19, 343-351 (Pubitemid 38787388)
    • (2004) Journal of Bone and Mineral Research , vol.19 , Issue.3 , pp. 343-351
    • Rubin, C.T.1    Recker, R.2    Cullen, D.3    Ryaby, J.4    McCabe, J.5    McLeod, K.6
  • 54
    • 81055155533 scopus 로고    scopus 로고
    • Effect of 12 months of whole-body vibration therapy on bone density and structure in postmenopausal women: A randomized trial
    • Slatkovska, L., Alibhai, S. M., Beyene, J., Hu, H., Demaras, A., and Cheung, A. M. (2011) Effect of 12 months of whole-body vibration therapy on bone density and structure in postmenopausal women: a randomized trial. Ann. Intern. Med. 155, 668-679, W205
    • (2011) Ann. Intern. Med. , vol.155
    • Slatkovska, L.1    Alibhai, S.M.2    Beyene, J.3    Hu, H.4    Demaras, A.5    Cheung, A.M.6
  • 55
    • 77953024397 scopus 로고    scopus 로고
    • Effect of low-magnitude, high-frequency vibration on osteocytes in the regulation of osteoclasts
    • Lau, E., Al-Dujaili, S., Guenther, A., Liu, D., Wang, L., and You, L. (2010) Effect of low-magnitude, high-frequency vibration on osteocytes in the regulation of osteoclasts. Bone 46, 1508-1515
    • (2010) Bone , vol.46 , pp. 1508-1515
    • Lau, E.1    Al-Dujaili, S.2    Guenther, A.3    Liu, D.4    Wang, L.5    You, L.6
  • 56
    • 80054920324 scopus 로고    scopus 로고
    • Mechanically induced focal adhesion assembly amplifies anti-adipogenic pathways in mesenchymal stem cells
    • Sen, B., Guilluy, C., Xie, Z., Case, N., Styner, M., Thomas, J., Oguz, I., Rubin, C., Burridge, K., and Rubin, J. (2011) Mechanically induced focal adhesion assembly amplifies anti-adipogenic pathways in mesenchymal stem cells. Stem Cells 29, 1829-1836
    • (2011) Stem Cells , vol.29 , pp. 1829-1836
    • Sen, B.1    Guilluy, C.2    Xie, Z.3    Case, N.4    Styner, M.5    Thomas, J.6    Oguz, I.7    Rubin, C.8    Burridge, K.9    Rubin, J.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.