Preparation of an antitumor and antivirus agent: Chemical modification of α-MMC and MAP30 from Momordica Charantia L. with covalent conjugation of polyethyelene glycol

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 3133-3142

  Meng, Yao ^a,b   Liu, Shuangfeng ^a   Li, Juan ^c   Meng, Yanfa ^c   Zhao, Xiaojun ^b,d  

^a CHENGDU MEDICAL COLLEGE   (China)

^b SICHUAN UNIVERSITY   (China)

^c SICHUAN UNIVERSITY   (China)

^d Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

(mPEG)2 Lys NHS (20 kDa); Alpha momorcharin; Antitumor; Antivirus; Immunogenicity; Immunogenicity Lys NHS (20 kDa); Momordica anti HIV protein; Ribosome inactivating proteins

Indexed keywords

ALPHA MOMORCHARIN; ANTINEOPLASTIC AGENT; ANTIVIRUS AGENT; MACROGOL; MOMORDICA ANTI HUMAN IMMUNODEFICIENCY VIRUS PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CHORIOCARCINOMA; CONTROLLED STUDY; DRUG FORMULATION; DRUG RELEASE; DRUG SCREENING; ELECTROSPRAY MASS SPECTROMETRY; HERPES SIMPLEX VIRUS 1; IMMUNOGENICITY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOMORDICA CHARANTIA; NONHUMAN; PLANT SEED; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN PURIFICATION; PROTEIN SYNTHESIS; RAT; SEQUENCE ANALYSIS; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIVIRAL AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; HERPESVIRUS 1, HUMAN; HUMANS; IMMUNOGLOBULIN G; MOMORDICA CHARANTIA; POLYETHYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY; RIBOSOME INACTIVATING PROTEINS; RIBOSOME INACTIVATING PROTEINS, TYPE 2; SEEDS; VERO CELLS;

HUMAN HERPESVIRUS 1; MOMORDICA; MOMORDICA CHARANTIA;

EID: 84870323472     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S30631     Document Type: Article

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