Clinical efficacy of a dry extract of five herbal drugs in acute viral rhinosinusitis

Rhinology

Volumn 50, Issue 4, 2012, Pages

  Jund, R ^a   Mondigler, M ^a   Steindl, H ^a   Stammer, H ^b   Stierna, P ^c   Bachert, Claus ^d  

^a Bionorica SE ^*  (Germany)

^b Karolinska Institut   (Germany)

^c KAROLINSKA INSTITUTE   (Sweden)

^d GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Acute viral rhinosinusitis; Herbal dry extract; Major symptom score (MSS); Sino nasal outcome test(SNOT) 20; Ultrasonography

Indexed keywords

BNO 1016; PLANT EXTRACT;

ACUTE DISEASE; ADULT; AGED; ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; ECHOGRAPHY; FEMALE; GENTIAN; HUMAN; MALE; MIDDLE AGED; PARANASAL SINUS; PHYTOTHERAPY; PRIMULACEAE; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RHINITIS; RUMEX; SAMBUCUS; SINUSITIS; TREATMENT OUTCOME; VERBENACEAE; VIROLOGY;

ACUTE DISEASE; ADULT; AGED; DOUBLE-BLIND METHOD; FEMALE; GENTIANA; HUMANS; MALE; MIDDLE AGED; PARANASAL SINUSES; PHYTOTHERAPY; PLANT EXTRACTS; PRIMULA; PROSPECTIVE STUDIES; RHINITIS; RUMEX; SAMBUCUS; SINUSITIS; TREATMENT OUTCOME; VERBENA; YOUNG ADULT;

EID: 84870311385     PISSN: 03000729     EISSN: None     Source Type: Journal    
DOI: 10.4193/Rhino.12.015     Document Type: Article

References (16)

1. Fokkens W, Lund V, Mullol J, et al. EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. Rhinology. 2012; supplement 23: 1-299.
2. Masood A, Moumoulidis I, Panesar J. Acute rhinosinusitis in adults: an update on current management. Postgrad Med J. 2007; 83: 402-408.
3. Hellgren J, Cervin A, Nordling S, Bergman A, Cardell LO. Allergic rhinitis and the common cold - high cost to society. Allergy. 2010; 65: 776-783.
4. Melzer J, Saller R, Schapowal A, Brignoli R. Systematic Review of Clinical Data with BNO 101 (BNO 101) in the Treatment of Sinusitis. Forschende Komplementärmedizin. 2006; 13: 78-87.
5. Bachert C, Schapowal A, Funk P, Kieser M. Treatment of acute rhinosinusitis with the preparation from Pelargonium sidoides EPs 7630: a randomized, double-blind, placebocontrolled trial. Rhinology. 2009; 47: 51-58.
6. Timmer A, Günther J, Rücker G, Motschall E, Antes G, Kern WV. Pelargonium sidoides extract for acute respiratory tract infections. Cochrane Database Syst Rev. 2008; 3: CD006323.
7. Guo R, Canter PH, Ernst E. Herbal medicines for the treatment of rhinosinusitis: a systematic review. Otolaryngol Head Neck Surg. 2006; 135: 496-506.
8. Ismail C. Pharmacology of Sinupret. Recent results on the rational for the Sinupret compound. HNO. 2005; 53 (Suppl 1): S38-S42.
9. März RW, Ismail C, Popp MA. Profile and effectiveness of a phytogenic combination preparation for treatment of sinusitis. Wien Med Wochenschr. 1999; 149: 202-208.
10. Baumann I, Blumenstock G, DeMaddalena H, Piccirillo JF, Plinkert PK. Quality of life in patients with chronic rhinosinusitis: validation of the Sino-Nasal Outcome Test-20 German Adapted Version. HNO. 2007; 55: 42-47.
11. World Medical Association (WMA): WMA Declaration of Helsinki - Ethical principles for medicinal research involving human patients. Adopted by the 18th WMA General Assembly Helsinki, Finland June 1964, and amended by the 48th WMA General Assembly. Somerset West, Republic of South Africa October 1996.
12. EMEA - The European Agency for the Evaluation of Medicinal Products: ICH Topic E6. Note for Guidance on Good Clinical Practice (CPMP/ ICH/ 135/ 95). Step 5. Consolidated Guideline 1 May 1996/ Date for coming into operation: 17 January 1997.
13. Meltzer EO, Bachert C, Staudinger H. Treating acute rhinosinusitis: comparing efficacy and safety of mometasone furoate nasal spray, amoxicillin, and placebo. J Allergy Clin Immunol. 2005; 116: 1289-1295.
14. Revicki DA, Margolis MK, Thompson CL, Meltzer EO, Sandor DW, Shaw JW. Major symptom score utility index for patients with acute rhinosinusitis. Am J Rhinol Allergy. 2011; 25: 99-106.
15. Young J, De Sutter A, Merenstein D, et al. Antibiotics for adults with clinically diagnosed acute rhinosinusitis: a meta-analysis of individual patient data. Lancet. 2008; 371: 908-914.
16. Zalmanovici Trestioreanu A, Yaphe J. Intranasal steroids for acute sinusitis (Review); The Cochrane Library, 2010, Issue 7.