Anti-inflammatory effects and acute toxicity of hydroethanolic extract of Jacaranda decurrens roots in adult male rats

Journal of Ethnopharmacology

Volumn 144, Issue 3, 2012, Pages 802-805

  Santos, Joyce Alencar ^a   Arruda, Aline ^a   Silva, Magaiver Andrade ^a   Cardoso, Claudia Andrea Lima ^b   Vieira, Maria Do Carmo ^a   Kassuya, Cândida Aparecida Leite ^a   Arena, Arielle Cristina ^c  

^a UNIVERSIDADE FEDERAL DA GRANDE DOURADOS   (Brazil)

^b UNIVERSIDADE ESTADUAL DE MATO GROSSO DO SUL   (Brazil)

^c SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Carrageenan; Inflammation; Jacaranda decurrens; Paw edema; Toxicity

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ANTIINFLAMMATORY AGENT; ASPARTATE AMINOTRANSFERASE; CARRAGEENAN; CREATININE; DEXAMETHASONE; GAMMA GLUTAMYLTRANSFERASE; JACARANDA DECURRENS EXTRACT; MYELOPEROXIDASE; PLANT EXTRACT; UNCLASSIFIED DRUG; UREA;

ACUTE TOXICITY; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BEHAVIOR; BODY WEIGHT; CREATININE BLOOD LEVEL; DOSE RESPONSE; DRUG EXPOSURE; DRUG MEGADOSE; ENZYME ACTIVITY; EOSINOPHIL COUNT; ERYTHROCYTE COUNT; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HEMATOCRIT; JACARANDA DECURRENS; LD 50; LIVER WEIGHT; LUNG WEIGHT; LYMPHOCYTE COUNT; MALE; MEDICINAL PLANT; MONOCYTE; NEUTROPHIL COUNT; NONHUMAN; PAW EDEMA; PLANT ROOT; RAT; THROMBOCYTE COUNT; TOXICITY TESTING;

ACETATES; ANIMALS; ANTI-INFLAMMATORY AGENTS; BIGNONIACEAE; CARRAGEENAN; EDEMA; ETHANOL; MALE; METHANOL; PEROXIDASE; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; RATS; RATS, WISTAR; SOLVENTS; TOXICITY TESTS, ACUTE; WATER;

BIGNONIACEAE; JACARANDA; RATTUS;

EID: 84870299833     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.10.024     Document Type: Article

References (18)

1. T. Balani, S. Agrawal, and A.M. Thaker Hematological and biochemical changes due to short-term oral administration of imidacloprid Toxicology International 18 2011 2 6
2. M. Batlouni Anti-inflamatórios não esteroides: efeitos cardiovasculares, cérebro-vasculares e renais Arquivos Brasileiros de Cardiologia 94 2010 556 563
3. B.W. Bertoni, M.P.C. Telles, M.G. Malosso, S.C.Z. Torres, J.O. Pereira, M.V. Lourenço, S.C. França, and A.M. Pereira Genetic diversity in natural populations of Jacaranda decurrens Cham. determined using RAPD and AFLP markers Genetics and Molecular Biology 33 2010 532 540
4. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Analytical Biochemistry 72 1976 248 254
5. Brazilian Health Surveillance Agency (ANVISA) Guide for Conducting Non-Clinical Safety Studies Required for Drug Development vol. 1 2010 p. 37
6. D.A. Cabrini, H.H. Moresco, P. Imazu, C.D. Silva, and E.F. Pietrovski Analysis of the potential topical anti-inflammatory activity of Averrhoa carambola L. in mice Evidence-based Complementary Alternative Medicine 2011 1 7
7. C.A.D. Carvalho, M.V. Lourenço, B.W. Bertoni, S.C. França, P.S. Pereira, A.L. Fachin, and A.M.S. Pereira Atividade antioxidante de Jacaranda decurrens Cham.; Bignoniaceae Revista Brasileira de Farmacognosia 19 2009 592 598
8. L.M. De Young, J.B. Kheifets, S.J. Ballaron, and J.M. Young Edema and cell infiltration in the phorbol ester-treated mouse ear are temporally separate and can be differentially modulated by pharmacologic agents Agents and Actions 26 1989 335 376
9. M. Di Rosa, J.P. Giroud, and D.A. Willoughby Studies on the mediators of the acute inflammatory response induced in rats in different sites by carrageenan and turpentine Journal of Pathology 104 1971 15 44
10. C.A. Kassuya, A. Cremoneze, L.F. Barros, A.S. Simas, F.R. Lapa, R. Mello-Silva, M.E. Stefanello, and A.R. Zampronio Antipyretic and anti-inflammatory properties of the ethanolic extract, dichloromethane fraction and costunolide from Magnolia ovata (Magnoliaceae) Journal of Ethnopharmacology 124 2009 369 376
11. S.B. Mahato, and A.P. Kundu Spectra of pentacyclic triterpenoids-a complication and some salient features Phytochemistry 37 1994 1517
12. G.P. Nunes, M.F. Silva, U.M. Resende, and J.M. Siqueira Plantas medicinais comercializadas por raizeiros no Centro de Campo Grande, Mato Grosso do Sul Revista Brasileira de Farmacognosia 13 2003 83 92
13. Organisation for Economic Co-operation and Development (OECD) Guideline 425:Acute Oral Toxicity-Up-and-Down-Procedure 4 2008 Head of Publications Service Paris p. 27
14. K. Subbaramaiah, P. Michaluart, M.B. Sporn, and A.J. Dannenberg Ursolic acid inhibits cyclooxygenase-2 transcription in human mammary epithelial cells Cancer Research 60 2000 2399 2453
15. A.T.C. Taketa, E. Breitmaier, and E.P. Schenkel Tritepenos de Hyptis fasciculata Benth Journal of the Brazilian Chemical Society 15 2004 205
16. L.M.F. Tresvenzol, J.R. Paula, A.F. Ricardo, H.D. Ferreira, and D.T. Zatta Study about informal trade of medicinal plants in Goiania and neighboring cities Brazil. Revista Eletrônica de Farmácia 3 2006 23 28
17. H. Uzkeser, E. Cadirci, Z. Halici, F. Odabasoglu, B. Polat, T.N. Yuksel, S. Ozaltin, and F. Atalay Anti-inflammatory and antinociceptive effects of salbutamol on acute and chronic models of inflammation in rats: involvement of an antioxidant mechanism Mediators of Inflammation 2012 2012 1 10
18. D.T. Zatta, F.C. Pimenta, L.M.F. Tresvenzol, T.S. Fiuza, M.T.F. Bara, L.C. Cunha, L.L. Pucci, C.F.D. Garrote, F.N.M. Oliveira, and J.R. Paula Study of antibacterial activity against Pseudomonas aeruginosa strains and acute toxicity of Jacaranda decurrens leaves Latin American Journal of Pharmacy 28 2009 485 494