The detection of occult HBV infection in patients with HBsAg negative pattern by real-time PCR method

Transfusion and Apheresis Science

Volumn 47, Issue 3, 2012, Pages 283-287

  Izmirli, Sena ^a   Celik, Deniz Gozde ^a   Yuksel, Pelin ^a   Saribas, Suat ^a   Aslan, Mustafa ^a   Ergin, Sevgi ^a   Bahar, Hrisi ^a   Sen, Sümeyye ^a   Cakal, Bulent ^b   Oner, Ali ^b   Kocazeybek, Bekir ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Isolated Anti HBc infections; Occult HBV infection

Indexed keywords

ALANINE AMINOTRANSFERASE; HEPATITIS B CORE ANTIBODY; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B VACCINE; VIRUS DNA;

ADOLESCENT; ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; BLOOD TRANSFUSION; CHILD; CONTROLLED STUDY; FEMALE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL DEVICE; NUCLEIC ACID AMPLIFICATION; OCCULT HEPATITIS B INFECTION; PRESCHOOL CHILD; REAL TIME POLYMERASE CHAIN REACTION; SCHOOL CHILD; SENSITIVITY ANALYSIS; VIRUS TRANSMISSION;

ADOLESCENT; ADULT; AGED; CHILD; CHILD, PRESCHOOL; CROSS-SECTIONAL STUDIES; DNA, VIRAL; FEMALE; HEPATITIS B; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HUMANS; MALE; MIDDLE AGED; REAL-TIME POLYMERASE CHAIN REACTION; YOUNG ADULT;

EID: 84870296416     PISSN: 14730502     EISSN: 18781683     Source Type: Journal    
DOI: 10.1016/j.transci.2012.07.009     Document Type: Article

References (25)

1. Maddrey W.C. Hepatitis B: an important public health issue. J Med Virol 2000, 61:326-362.
2. Hu K.-Q. Occult hepatitis B virus infection and its clinical implications. J Viral Hepat 2002, 9:243-257.
3. Torbenson M., Thomas D.L. Occult HBV. Lancet Infect Dis 2002, 2:479-486.
4. Schreiber G.B., Busch M.P., Kleinman S.H., Korelitz J.J. FTR-EDS. The risk of transfusion transmitted viral infections. N Engl J Med 1996, 334:1685-1690.
5. Dickson R.C., Everhart J.C., Lake J.R., Wei Y., Seaberg E.C., Wiesner R.H., et al. Transmission of hepatitis B by transplantation of livers from donors positive for antibody to hepatitis B core antigen. Gastroenterology 1997, 113:1668-1674.
6. Hollinger F.B., Sood G. Occult hepatitis B virus infection: a covert operation. J Viral Hepat 2010, 17:1-15.
7. Marusawa H., Uemoto S., Hijikata M., Ueda Y., Tanaka K., Shimotohno K., et al. Latent hepatitis B virus infection in healthy individuals with antibodies to hepatitis B core antigen. Hepatology 2000, 31:488-495.
8. Badur S. Non-A, non-B hepatitis viruses. J Klimik 1988, 1:20-24.
9. Chazouilleres O., Mamish D., Kim M., Carey K., Ferrell L., Roberts J.P., et al. 'Occult hepatitis' B virus as source of infection in liver transplant recipients. Lancet 1994, 343:1685-1690.
10. Bal S.H., Heper Y., Kumaş L.T., Mi{dotless}sti{dotless}k R., Töre O. Investigation of the presence of HBV-DNA in isolated Anti-HBc positive cases and their importance in blood banking. Bul Microbiol 2009, 43:243-250.
11. Altunay H., Kosan E., Birinci I., Aksoy A., Kirali K., Saribas S., et al. Are isolated anti-HBc blood donors in high risk group? The detection of HBV DNA in isolated anti-HBc cases with nucleic acid amplification test (NAT) based on transcription-mediated amplification (TMA) and HBV discrimination. Transfus Apher Sci 2010, 43:265-268.
12. Minuk G.Y., Sun D., Uhanova J., Zhang M., Caouette S., Nicolle L.E., et al. Occult hepatitis B virus infection in a North American community-based population. J Hepatol 2005, 42:480-485.
13. Liang T.J., Bodenheimer H.C., Yankee Ronald Brown N.V., Chang K., Huang J., Wands J.R. Presence of hepatitis B and C viral genomes in US blood donors as detected by polymerase chain reaction amplification. J Med Virol 1994, 42:151-157.
14. Antar W., El-Shokry M.H., Abd El Hamid1 W.A., Helmy M.F. Significance of detecting anti-HBc among Egyptian male blood donors negative for HBsAg. Transfus Med 2010, 20:409-413.
15. Ali R., Khan L.A., Husain S.A., Singla R., Kar P. Significance of anti-HBc screening of blood donors & its association with occult hepatitis B virus infection: implications for blood transfusion. Indian J Med Res 2010, 132:312-317.
16. Zervou E.K., Dalekos G.N., Boumba D.S., Tsianos E.V. Value of anti-HBc screening of blood donors for prevention of HBV infection: results of a 3-year prospective study in Northwestern Greece. Transfusion 2001, 41:652-658.
17. Douglas D.D., Taswell H.F., Rakela J., Rabe D. Absence of hepatitis B virus DNA detected by polymerase chain reaction in blood donors who are hepatitis B surface antigen negative and antibody to hepatitis B core antigen positive from a United States population with a low prevalence of hepatitis B serologic markers. Transfusion 1993, 33:212-216.
18. Shih L.N., Sheu J.C., Wang J.T., Huang G.T., Yang P.M., Lee H.S., et al. Serum hepatitis B virus DNA in healthy HBsAg-negative Chinese adults evaluated by polymerase chain reaction. J Med Virol 2000, 32:257-280.
19. Song E.Y., Yun Y.M., Park M.H., Seo D.H. Prevalence of occult hepatitis B virus infection in a general adult population in Korea. Intervirology 2009, 52:57-62.
20. Kocazeybek B., Ordu A., Ayyi{dotless}ldi{dotless}z A., Aslan M. The investigation of HBV-DNA in naturally immunized cases with hepatitis B infection. J Viral Hepat 2000, 1:30-32.
21. Aspinall S., Steele A.D., Peenze I. Detection and quantitation of hepatitis B virus DNA: comparison of two commercial hybridization assays with polymerase chain reaction. J Viral Hepat 1995, 2:107-111.
22. Kosan E., Kocazeybek B., Altunay H., Aymelek M., Alan E., et al. Can the nucleic acid amplification test (NAT) be an alternative to the serologic tests? A prospective study, the results of 18200 blood donors from the Turkish Red Crescent. Transfus Apher Sci 2010 Dec, 43:269-272.
23. Thomas H.C., Carman W.F. Envelope and precore/core variants of hepatitis B virus. Gastroenterol Clin North Am 1994, 23:499-514.
24. Carman W.F., Zanetti A.R., Karayiannis P., et al. Vaccine-induced escape mutant of hepatitis B virus. Lancet 1990, 336:325-329.
25. Thomas H.C. The emergence of envelope and precore/core variants of hepatitis B virus: the potential role of antibody selection. J Hepatol 1995, 22:1-8.