Effect of vagus nerve stimulation in an adult patient with dravet syndrome: Contribution to sudden unexpected death in epilepsy risk reduction?

European Neurology

Volumn 69, Issue 2, 2013, Pages 119-121

  Spatola, Marianna ^a   Jeannet, Pierre Yves ^b   Pollo, Claudio ^b   Wider, Christian ^a   Labrum, Robyn ^c   Rossetti, Andrea O ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

Author keywords

Alertness; Cardiac dysfunction; Epilepsy; Neuropsychological impairment; SCN1A gene; Treatment; Vagal nerve stimulator

Indexed keywords

BENZODIAZEPINE DERIVATIVE; CARBAMAZEPINE; CLOBAZAM; ETIRACETAM; GABAPENTIN; LAMOTRIGINE; LYSINE; PHENOBARBITAL; PHENYTOIN; RETIGABINE; SERINE; SODIUM CHANNEL NAV1.1; VALPROIC ACID; VIGABATRIN;

ADULT; ALERTNESS; ANTICONVULSANT THERAPY; ARTICLE; CASE REPORT; COGNITION; DISEASE DURATION; DNA SEQUENCE; FOCAL EPILEPSY; FOLLOW UP; GENE DELETION; HETEROZYGOTE; HUMAN; MALE; NERVE STIMULATOR; PRIORITY JOURNAL; PSYCHOMOTOR RETARDATION; RISK REDUCTION; SEVERE MYOCLONIC EPILEPSY IN INFANCY; SUDDEN DEATH; TONIC CLONIC SEIZURE; VAGUS NERVE STIMULATION; CONVULSION; DISEASE ASSOCIATION; DISEASE SEVERITY; IMPLANTED VAGUS NERVE STIMULATOR; PSYCHOMOTOR DISORDER;

DEATH, SUDDEN; EPILEPSIES, MYOCLONIC; HUMANS; MALE; RISK REDUCTION BEHAVIOR; TREATMENT OUTCOME; VAGUS NERVE STIMULATION; YOUNG ADULT;

EID: 84870296237     PISSN: 00143022     EISSN: 14219913     Source Type: Journal    
DOI: 10.1159/000345132     Document Type: Article

References (10)

1. Genton P, Velizarova R, Dravet C: Dravet syndrome: The long-Term outcome. Epilepsia 2011; 52(SUPPL2):44-49
2. Claes L, Del-Favero J, Ceulemans B, Lagae L, Van Broeckhoven C, De Jonghe P: De novo mutations in the sodium-channel gene SCN1A cause severe myoclonic epilepsy of infancy. Am J Hum Genet 2001; 68: 1327-1332
3. McHugh JC, Singh HW, Phillips J, Murphy K, Doherty CP, Delanty N: Outcome measurement after vagal nerve stimulation therapy: Proposal of a new classification. Epilepsia 2007; 48: 375-378
4. Zamponi N, Passamonti C, Cappanera S, Petrelli C: Clinical course of young patients with Dravet syndrome after vagal nerve stimulation. Eur J Paediatr Neurol 2011; 15: 8-14
5. Hesdorffer DC, Tomson T, Benn E, Sander JW, Nilsson L, Langan Y, Walczak TS, Beghi E, Brodie MJ, Hauser A: Combined analysis of risk factors for SUDEP. Epilepsia 2011; 52: 1150-1159
6. Delogu AB, Spinelli A, Battaglia D, Dravet C, De Nisco A, Saracino A, Romagnoli C, Lanza GA, Crea F: Electrical and autonomic cardiac function in patients with Dravet syndrome. Epilepsia 2011; 52(SUPPL2):55-58
7. Maier SK, Westenbroek RE, Yamanushi TT, Dobrzynski H, Boyett MR, Catterall WA, Scheuer T: An unexpected requirement for brain-Type sodium channels for control of heart rate in the mouse sinoatrial node. Proc Natl Acad Sci USA 2003; 100: 3507-3512
8. Amin AS, Asghari-Roodsari A, Tan HL: Cardiac sodium channelopathies. Pflügers Arch 2010; 460: 223-237
9. Iriarte J, Urrestarazu E, Alegre M, Macías A, Gómez A, Amaro P, Artieda J, Viteri C: Lateonset periodic asystolia during vagus nerve stimulation. Epilepsia 2009; 50: 928-932
10. Annegers JF, Coan SP, Hauser WA, Leestma J: Epilepsy, vagal nerve stimulation by the NCP system, all-cause mortality, and sudden, unexpected, unexplained death. Epilepsia 2000; 41: 549-553