Identification of Small Molecules that Interfere with H1N1 InfluenzaA Viral Replication

ChemMedChem

Volumn 7, Issue 12, 2012, Pages 2227-2235

  Bottini, Angel ^a   De, Surya K ^a   Baaten, Bas J G ^a   Wu, Bainan ^a   Barile, Elisa ^a   Soonthornvacharin, Stephen ^a   Stebbins, John L ^a   Bradley, Linda M ^a   Chanda, Sumit K ^a   Pellecchia, Maurizio ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

Antiviral agents; Drug discovery; Influenza; Tetrazoles; Ugi reaction

Indexed keywords

LUCIFERASE; OSELTAMIVIR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; FEMALE; IN VIVO STUDY; INFLUENZA VIRUS A H1N1; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; VIRUS REPLICATION; VIRUS RESISTANCE; VIRUS STRAIN;

ANIMALS; ANTIVIRAL AGENTS; FEMALE; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; MICE; MICE, INBRED C57BL; ORTHOMYXOVIRIDAE INFECTIONS; REAL-TIME POLYMERASE CHAIN REACTION; SMALL MOLECULE LIBRARIES; TETRAZOLES; VIRUS REPLICATION;

EID: 84870279731     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201200453     Document Type: Article

References (14)

1. M. Lakadamyali, M. J. Rust, X. Zhuang, Microbes Infect. 2004, 6, 929-936.
2. F. Ciampor, P. M. Bayley, M. V. Nermut, E. M. Hirst, R. J. Sugrue, A. J. Hay, Virology 1992, 188, 14-24.
3. R. M. Krug, J. M. Aramini, Trends Pharmacol. Sci. 2009, 30, 269-277.
4. R. König, S. Stertz, Y. Zhou, A. Inoue, H. H. Hoffmann, S. Bhattacharyya, J. G. Alamares, D. M. Tscherne, M. B. Ortigoza, Y. Liang, Q. Gao, S. E. Andrews, S. Bandyopadhyay, P. DeJesus, B. P. Tu, L. Pache, C. Shih, A. Orth, G. Bonamy, L. Miraglia, T. Ideker, A. Garcia-Sastre, J. A. Young, P. Palese, M. L. Shaw, S. K. Chanda, Nature 2010, 463, 813-817.
5. T. Watanabe, S. Watanabe, Y. Kawaoka, Cell Host Microbe 2010, 7, 427-439.
6. A. Srivastava, R. M. Singh, Indian J. Chem. Sect. B 2005, 44, 1868-1875.
7. F. Constabel, I. Ugi, Tetrahedron 2001, 57, 5785-5789.
8. S. Gaitonde, S. K. De, M. Tcherpakov, A. Dewing, H. Yuan, M. Riel-Mehan, S. Krajewski, G. Robertson, M. Pellecchia, Z. Ronai, Pigm. Cell Melanoma Res. 2009, 22, 187-195.
9. J. McKimm-Breschkin, T. Trivedi, A. Hampson, A. Hay, A. Klimov, M. Tashiro, F. Hayden, M. Zambon, Antimicrob. Agents Chemother. 2003, 47, 2264-2272.
10. J. R. Schnell, J. J. Chou, Nature 2008, 451, 591-595.
11. M. Yamashita, T. Tomozawa, M. Kakuta, A. Tokumitsu, H. Nasu, S. Kubo, Antimicrob. Agents Chemother. 2009, 53, 186-192.
12. K. Yonemaru, H. Sakai, M. Murakami, A. Kodama, T. Mori, T. Yanai, K. Maruo, T. Masegi, J. Vet. Med. Sci. 2007, 69, 271-278.
13. B. Hayes, S. R. Fagerlie, A. Ramakrishnan, S. Baran, M. Harkey, L. Graf, M. Bar, A. Bendoraite, M. Tewari, B. Torok-Storb, Stem Cells 2008, 26, 465-473.
14. L. M. Bradley, M. F. Douglass, D. Chatterjee, S. Akira, B. J. Baaten, PLoS Pathog. 2012, 8, e1002641.