Amyotrophic lateral sclerosis with positive anti-acetylcholine receptor antibodies. case report and review of the literature

Journal of Clinical Neuromuscular Disease

Volumn 14, Issue 2, 2012, Pages 82-85

  Mehanna, Raja ^a   Patton, Eddie L ^a   Phan, Cecile L ^a   Harati, Yadollah ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

acetylcholine receptor antibodies; amyotrophic lateral sclerosis; myasthenia gravis

Indexed keywords

CHOLINERGIC RECEPTOR ANTIBODY;

AGED; AMYOTROPHIC LATERAL SCLEROSIS; CASE REPORT; DEGENERATIVE DISEASE; FEMALE; HUMAN; MOTONEURON; NERVE STIMULATION; NEUROLOGIC EXAMINATION; PRIORITY JOURNAL; REPETITIVE NERVE STIMULATION; REVIEW;

AGED; AMYOTROPHIC LATERAL SCLEROSIS; AUTOANTIBODIES; ELECTROMYOGRAPHY; FEMALE; HUMANS; MUSCLE, SKELETAL; NEURAL CONDUCTION; RECEPTORS, CHOLINERGIC;

EID: 84870267224     PISSN: 15220443     EISSN: 15371611     Source Type: Journal    
DOI: 10.1097/CND.0b013e31824db163     Document Type: Review

References (14)

1. Vincent A, Newsom-Davis J. Acetylcholine receptor antibody as a diagnostic test for myasthenia gravis: results in 153 validated cases and 2967 diagnostic assays. J Neurol Neurosurg Psychiatry. 1985;48: 1246-1252. (Pubitemid 16229407)
2. Apiwattanakul M, McKeon A, Pittock S, et al. Eliminating false-positive results in serum tests for neuromuscular autoimmunity. Muscle Nerve. 2010; 41:702-704.
3. Brooks BR, Miller RG, Swash M, et al. El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler. 2000;1:293-300.
4. Mittag TW, Caroscio J. False-positive immunoassay for acetyl-choline receptor antibody in amyotrophic lateral sclerosis. N Engl J Med. 1980;302:868.
5. Restivo DA, Bianconi C, Ravenni R, et al. ALS and myasthenia: an unusual association in a patient treated with riluzole. Muscle Nerve. 2000;23:294- 295. (Pubitemid 30064958)
6. OkuyamaY, MizunoT, Inoue H, et al. Amyotrophic lateral sclerosis with anti-acetylcholine receptor antibody. Int Med. 1997;36:312-315.
7. Nwosu VK, Royer JA, Stickler DE. Voltage gated potassium channel antibodies in amyotrophic lateral sclerosis. Amyotroph Lateral Scler. 2010; 11:392-394.
8. Appel S, Engelhardt J, Garcia J, et al. Immunoglobulins from animal models of motor neuron disease and from amyotrophic lateral sclerosis patients passively transfer physiological abnormalities to the neuromuscular junction. Proc Natl Acad Sci USA. 1991;88: 647-651. (Pubitemid 21915523)
9. Smith RG, Hamilton S, Hofmann F, et al. Serum antibodies to L-type calcium channels in patients with amyotrophic lateral sclerosis. N Engl J Med. 1992;327:1721-1728.
10. Lennon VA, Kryzer TJ, Griesmann GE, et al. Calciumchannel antibodies in the Lambert-Eaton syndrome and other paraneoplastic syndromes. N Engl J Med. 1995;332:1467-1474.
11. Drachman DB, Fishman PS, Rothstein JD, et al. Amyotrophic lateral sclerosis. An autoimmune disease? Adv Neurol. 1995;68:59-65.
12. Arsac C, Raymond C, Martin-Moutot N, et al. Immunoassays fail to detect antibodies against neuronal calcium channels in amyotrophic lateral sclerosis serum. Ann Neurol. 1996;40:695-700. (Pubitemid 26415180)
13. Nyormoi O. Proteolytic activity in amyotrophic lateral sclerosis IgG preparations. Ann Neurol. 1996;40:701-706. (Pubitemid 26415181)
14. Vincent A, Drachman DB. Amyotrophic lateral sclerosis and antibodies to voltage-gated calcium channels- new doubts. Ann Neurol. 1996;40: 691-693.