Nox4- and Nox2-dependent oxidant production is required for VEGF-induced SERCA cysteine-674 S-glutathiolation and endothelial cell migration

Free Radical Biology and Medicine

Volumn 53, Issue 12, 2012, Pages 2327-2334

  Evangelista, Alicia M ^a   Thompson, Melissa D ^a   Bolotina, Victoria M ^a   Tong, Xiaoyong ^a   Cohen, Richard A ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Calcium; Endothelial cells; Free radicals; Hydrogen peroxide; Nox2; Nox4; SERCA; VEGF

Indexed keywords

CALCIUM ION; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; CYSTEINE; GLUTATHIONE; HYDROGEN PEROXIDE; MESSENGER RNA; OXIDIZING AGENT; PROTEIN SERCA2B; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SERINE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANGIOGENESIS; AORTA; ARTICLE; CALCIUM TRANSPORT; CELL MIGRATION; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; MUTATION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; REGULATORY MECHANISM; S GLUTATHIOLATION; SIGNAL TRANSDUCTION;

CALCIUM; ENDOTHELIAL CELLS; FREE RADICALS; HYDROGEN PEROXIDE; NOX2; NOX4; SERCA; VEGF;

CALCIUM SIGNALING; CATALASE; CELL MOVEMENT; CELLS, CULTURED; CYSTEINE; ENDOTHELIAL CELLS; GLUTATHIONE; HUMANS; HYDROGEN PEROXIDE; MEMBRANE GLYCOPROTEINS; NADPH OXIDASE; OXIDATION-REDUCTION; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SUPEROXIDE DISMUTASE; SUPEROXIDES; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84870199000     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.10.546     Document Type: Article

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