A new approach to structural integrity assessment based on axial and radial diffusivities

Functional Neurology

Volumn 27, Issue 2, 2012, Pages 85-90

  Wheeler Kingshott, Claudia A M ^a   Ciccarelli, Olga ^a   Schneider, Torben ^a   Alexander, Daniel C ^b   Cercignani, Mara ^c  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c BRIGHTON AND SUSSEX MEDICAL SCHOOL   (United Kingdom)

Author keywords

Axial diffusivity; Diffusion tensor; DTI; Eigenvalues; Radial diffusivity; Template

Indexed keywords

ADULT; ARTICLE; AXIAL DIFFUSIVITY; BRAIN MAPPING; CASE REPORT; CONTROLLED STUDY; DIFFUSION TENSOR IMAGING; FEMALE; FRACTIONAL ANISOTROPY; HUMAN; IMAGE ANALYSIS; IMAGE PROCESSING; MALE; MEASUREMENT; MULTIPLE SCLEROSIS; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; RADIAL DIFFUSIVITY; RADIOLOGICAL PARAMETERS; VOXEL BASED MORPHOMETRY; WHITE MATTER;

ADULT; ANISOTROPY; BRAIN; DIFFUSION TENSOR IMAGING; FEMALE; HUMANS; MALE; MIDDLE AGED; NERVE FIBERS, MYELINATED;

EID: 84870193140     PISSN: 03935264     EISSN: 19713274     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Basser PJ, Pierpaoli C. A simplified method to measure the diffusion tensor from seven MR images. Magn Reson Med 1998;39:928-934
2. Song SK, Sun SW, Ramsbottom MJ, Chang C, Russell J, Cross AH. Dysmyelination revealed through MRI as increased radial (but unchanged axial) diffusion of water. Neuroimage 2002;17:1429-1436
3. Rovaris M, Agosta F, Pagani E, Filippi M. Diffusion tensor MR imaging. Neuroimaging Clin N Am 2009;19:37-43
4. Wheeler-Kingshott CA, Cercignani M. About axial and radial diffusivities. Magn Reson Med 2009;61:1255-1260
5. McDonald WI, Compston A, Edan G et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol 2001;50:121-127
6. Cook PA, Symms M, Boulby PA, Alexander DC. Optimal acquisition orders of diffusion-weighted MRI measurements. J Magn Reson Imaging 2007;25:1051-1058
7. Tozer DJ, Chard DT, Bodini B et al. Linking white matter tracts to associated cortical grey matter: a tract extension methodology. Neuroimage 2012;59:3094-3102
8. Cook PA, Bai Y, Nedjati-Gilani K et al. Camino: Open-Source Diffusion-MRI Reconstruction and Processing. Proceedings of the International Society for Magnetic Resonance in Medicine 2006;14:2759
9. Alexander DC, Pierpaoli C, Basser PJ, Gee JC. Spatial transformations of diffusion tensor magnetic resonance images. IEEE Trans Med Imaging 2001;20:1131-1139
10. Field AS, Alexander AL, Wu YC, Hasan KM, Witwer B, Badie B. Diffusion tensor eigenvector directional color imaging patterns in the evaluation of cerebral white matter tracts altered by tumor. J Magn Reson Imaging 2004;2:555-562
11. Dutta R, Trapp BD. Mechanisms of neuronal dysfunction and degeneration in multiple sclerosis. Prog Neurobiol 2011;93:1-12
12. Peng H, Orlichenko A, Dawe RJ, Agam G, Zhang S, Arfanakis K. Development of a human brain diffusion tensor template. Neuroimage 2009;46:967-980
13. Salmond CH, Ashburner J, Vargha-Khadem F, Connelly A, Gadian DG, Friston KJ. Distributional assumptions in voxel-based morphometry. Neuroimage 2002;17:1027-1030
14. Bozzali M, Cercignani M, Baglio F et al. Voxel-wise analysis of diffusion tensor MRI improves the confidence of diagnosis of corticobasal degeneration non-invasively. Parkinsonism Relat Disord 2008;14:436-439
15. Ferraiuolo L, Kirby J, Grierson AJ, Sendtner M, Shaw PJ. Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis. Nat Rev Neurol 2011;7:616-630
16. Rizzo G, Martinelli P, Manners D et al. Diffusion-weighted brain imaging study of patients with clinical diagnosis of corticobasal degeneration, progressive supranuclear palsy and Parkinson's disease. Brain 2008;131:2690-2700
17. Song SK, Sun SW, Ju WK, Lin SJ, Cross AH, Neufeld AH. Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia. Neuroimage 2003;20:1714-1722
18. Song SK, Yoshino J, Le TQ et al. Demyelination increases radial diffusivity in corpus callosum of mouse brain. Neuroimage 2005;26:132-140