Epidemiology of oral clefts 2012: An international perspective

Frontiers of Oral Biology

Volumn 16, Issue , 2012, Pages 1-18

  Mossey, P A ^a   Modell, B ^b  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CLEFT LIP; CLEFT PALATE; COST OF ILLNESS; DEVELOPED COUNTRY; DEVELOPING COUNTRY; HEALTH; HEALTH CARE DISPARITY; HEALTH CARE QUALITY; HUMAN; PRIMARY PREVENTION; REVIEW; STATISTICS;

CLEFT LIP; CLEFT PALATE; COST OF ILLNESS; DEVELOPED COUNTRIES; DEVELOPING COUNTRIES; HEALTHCARE DISPARITIES; HUMANS; PRIMARY PREVENTION; QUALITY OF HEALTH CARE; WORLD HEALTH;

EID: 84870156851     PISSN: 14202433     EISSN: 16623770     Source Type: Book Series    
DOI: 10.1159/000337464     Document Type: Review

References (90)

1. Mossey PA, Little J: Epidemiology of oral clefts: an international perspective; in Wyszynski DF (ed): Cleft Lip and Palate. From Origin to Treatment. New York, Oxford University Press, 2002, chapt 12, pp 127-158.
2. Global Registry and Database on Craniofacial Anomalies. WHO Human Genetics Programme: Management of Noncommunicable Diseases: International Collaborative Research on Craniofacial Anomalies. Geneva, WHO, 2003.
3. Croen LA, Shaw GM, Wasserman CR, Tolarova MM: Racial and ethnic variations in the prevalence of orofacial clefts in California, 1983-1992. Am J Med Genet 1998;79:42-47. (Pubitemid 28402418)
4. Kirby R, Petrini J, Alter C: Collecting and interpreting birth defects surveillance data by Hispanic ethnicity: a comparative study. The Hispanic Ethnicity Birth Defects Workgroup. Teratology 2000;61:21-27. (Pubitemid 30040690)
5. Leck I, Lancashire RJ: Birth prevalence of malformations in members of different ethnic groups and in the offspring of matings between them, in Birmingham, England. J Epidemiol Community Health 1995;49:171-179.
6. Ching GHS, Chung CS: A genetic study of cleft lip and palate in Hawaii. 1. Interracial crosses. Am J Hum Genet 1974;26:162-172.
7. Tolarova MM, Cervenka J: Classification and birth prevalence of orofacial clefts. Am J Med Genet 1998;75:126-137. (Pubitemid 28034487)
8. Hagberg C, Larson O, Milerad J: Incidence of cleft lip and palate and risks of additional malformations. Cleft Palate Craniofac J 1997;35:40-45.
9. Online Mendelian Inheritance in Man, OMIM®. Baltimore, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, 2000. www URL: http://omim.org/
10. IPDTOC Working Group: Prevalence at birth of cleft lip with or without cleft palate: data from the International Perinatal Database of Typical Oral Clefts (IPDTOC). 2011;48:66-78.
11. Rittler M, Lopez-Camelo JS, Castilla EE, Bermejo E, Cocchi G, Correa A, Csaky-Szunyogh M, Danderfer R, De Vigan C, De Walle H, Da Grace Dutra M, Hirahara F, Martinez-Frias ML, Merlob P, Mutchinick O, Ritvanen A, et al: Preferential associations between oral clefts and other major congenital anomalies. Cleft Palate Craniofac J 2008;45:525-532.
12. Rittler M, Cosentino V, Lopez-Camelo JS, Murray JC, Wehby G, Castilla EE: Associated anomalies among infants with oral clefts at birth and during a 1-year follow-up. Am J Med Genet Part A 2011;155A:1588-1596.
13. Grosen D, Bille C, Pedersen JK, Skytthe A, Murray JC, Christensen K: Recurrence risk for offspring of twins discordant for oral cleft - a population-based cohort study of the Danish 1936-2004 cleft twin cohort. Am J Med Genet A 2011;152A:2468-2474.
14. Fogh-Anderson P: PhD Thesis, Copenhagen 1942.
15. Fraser GR, Calnan JS: Cleft lip and palate: seasonal incidence, birth weight, birth rank, sex, site, associated malformations and parental age. Arch Dis Child 1961;36:420-423.
16. Bonaiti C, Briard ML, Feingold J, Pavy B, Psaume J, Migne-Tufferaud G, Kaplan J: An epidemiological and genetic study of facial clefting in France: epidemiology and frequency in relatives. J Med Genet 1982;19:8-15. (Pubitemid 12186935)
17. Tolarova MM: Orofacial clefts in Czechoslovakia: incidence, genetics and prevention of cleft lip and palate over a 19-year period. Scand J Plast Reconstr Surg 1987;21:19-25.
18. Jensen BL, Kreiborg S, Dahl E, Fogh-Andersen P: Cleft lip and palate in Denmark 1976-1981: epidemiology variability and early somatic development. Cleft Palate J 1988;25:258-269.
19. Johnston MC, Brown KS: Human population data. General discussion. III. Prog Clin Biol Res 1980:1.
20. Mossey PA, Little J, Munger RG, Dixon MJ, Shaw WC: Cleft lip and palate. Lancet 2009;374:1773-1785.
21. Fujino H, Tanaka K, Sanui Y: Genetic study of cleft lips and cleft palates based upon 2,828 Japanese cases. Kyushu J Med Sci 1963;14:317-331.
22. Niswander JD, MacLean CJ, Chung CS, Dronamraju K: Sex ratio and cleft lip with or without cleft palate. Lancet 1972;ii:858-860.
23. Burdi AR, Silvey RG: Sexual differences in closure of the human palatal shelves. Cleft Palate J 1969;6:1-7.
24. Harville E W, Wilcox AJ, Lie RT, Vindeness H, Abyholm F: Cleft lip and palate versus cleft lip only: are they distinct defects? Am J Epidemiol 2005;162:448-453. (Pubitemid 41191430)
25. Calzolari E, Pierini A, Astolfi G, Bianchi F, Neville AJ, Rivieri F: Associated anomalies in multimalformed infants with cleft lip and palate: an epidemiologic study of nearly six million births in twenty-three EUROCAT registries. Am J Med Genet A 2007;143A:528-537. (Pubitemid 46348891)
26. Dolk H: EUROCAT: 25 years of European surveillance of congenital anomalies. Arch Dis Child Fetal Neonatal Ed 2005;90:F355-F358. (Pubitemid 41224066)
27. Vanderas AP: Incidence of cleft lip, cleft palate, and cleft lip and palate among races: a review. Cleft Palate J 1987; 24:216-225. (Pubitemid 17129972)
28. Milerad J, Larson O, Hagberg C, Ideberg M: Associated malformations in infants with cleft lip and palate: a prospective, population-based study. Pediatrics 1997;100:180-186. (Pubitemid 27328193)
29. Shafi T, Khan MR, Atiq M: Congenital heart disease and associated malformations in children with cleft lip and palate in Pakistan. Br J Plast Surg 2003;56:106-109. (Pubitemid 36763950)
30. Shaw GM, Carmichael SL, Yang W, Harris JA, Lammer EJ: Congenital malformations in births with orofacial clefts among 3.6 million California births, 1983-1997. Am J Med Genet Part A 2004;125A:250-256. (Pubitemid 38294842)
31. Stoll C, Alembik Y, Dott B, Roth MP: Associated malformations in cases with oral clefts. Cleft Palate Craniofac J 2000;37:41-47. (Pubitemid 30065017)
32. Rawashdeh MA, Jawdat Abu-Hawas B: Congenital associated malformations in a sample of Jordanian patients with cleft lip and palate. J Oral Maxillofac Surg 2008;66:2035-2041.
33. Kallen B, Harris J, Robert E: The epidemiology of orofacial clefts. 2. Associated malformations. J Craniofac Genet Dev Biol 1996;16:242-248. (Pubitemid 26394674)
34. Genisca AE, Frias JL, Broussard CS, Honein MA, Lammer EJ, Moore CA, Shaw GM, Murray JC, Yang W, Rasmussen SA: Orofacial clefts in The National Birth Defects Prevention Study (1997-2004). Am J Med Genet A 2009;149A:1149-1158.
35. Iregbulem LM: The incidence of cleft lip and palate in Nigeria. Cleft Palate J 1982;19:201-205. (Pubitemid 12055396)
36. Ogle OE: Incidence of cleft lip and palate in a newborn Zairian sample. Cleft Palate Craniofac J 1993;30:250-251.
37. Khan AA: Congenital malformation in African neonates in Nairobi. J Trop Med Hyg 1965;68:272.
38. Simpkiss M, Lowe A: Congenital abnormalities in the African newborn. Arch Dis Child 1961;36:404-405.
39. Gupta B: Incidence of congenital malformation in Nigerian children. West Afr Med J 1969;18:22-27.
40. Robinson DC, Shepherd JJ: The prevalence and natural history of cleft lip and palate in Uganda. Dev Med Child Neurol 1970;12:636-641.
41. Khrouf N, Spang R, Podgorna T, Miled SB, Moussaoui M, Chibani M: Malformations in 10,000 consecutive births in Tunis. Acta Paediatr Scand 1986;75:534-539. (Pubitemid 16100476)
42. Kromberg JGR, Jenkins T: Common birth defects in South African Blacks. S Afr Med J 1982;62.
43. Morrison G, Cronje AS, Van Vuuren I, Op't Hof J: The incidence of cleft lip and palate in the Western Cape. S Afr Med J 1985;68:576-577. (Pubitemid 16204723)
44. Butali A, Mossey PA: Epidemiology of orofacial clefts in Africa: methodological challenges in ascertainment. Pan Afr Med J 2009;2:1-11.
45. Myrianthopoulos NC, Chung CS: Congenital malformations in singletons: epidemiological survey. Report from the Collaborative Perinatal Project. New York, Stratton Intercontinental Medical Book Corp, 1974.
46. Wyszynski DF, Beaty TH, Maestri N: Genetics of non-syndromic cleft lip with or without cleft palate revisited. Cleft Palate Craniofac J 1996;33:406-417.
47. Das SK, Runnels RS, Smith JC, Cohly HH: Epidemiology of cleft lip and cleft palate in Mississippi. South Med J 1995;88:437-442.
48. Al-Johar A, Ravichandran K, Subhani S: Pattern of cleft lip and palate in hospitalbased population in Saudi Arabia: retrospective study. Cleft Palate Craniofac J 2008;45:592-596.
49. Kumar P, Hussain MT, Cardoso E, Hawary MB, Hassanain J: Facial clefts in Saudi Arabia: an epidemiologic analysis in 179 patients. Plast Reconstr Surg 1991;88:955-958.
50. Borkar AS: Epidemiology of facial clefts in the central province of Saudi Arabia. Br J Plast Surg 1993;46:673-675. (Pubitemid 24018297)
51. Aqrabawi HE: Facial cleft and associated anomalies: incidence among infants at a Jordanian medical centre. East Mediterr Health J 2008;14:356-359. (Pubitemid 351888497)
52. Rajab A, Thomas C: Oral clefts in the Sultanate of Oman. Eur J Plast Surg 2001;24:230-233. (Pubitemid 32998694)
53. Sabbagh HJ, Mossey PA, Innes NP: Prevalence of orofacial clefts in Saudi Arabia and neighboring countries: a systematic review. Saudi Dent J 2012;24:3-10.
54. Smahel Z, Brejcha M: Differences in craniofacial morphology between complete and incomplete unilateral cleft lip and palate in adults. Cleft Palate J 1983;20:113-127. (Pubitemid 13068626)
55. Nordin KE, Larson O, Nylén B, Eklund G: Early bone grafting in complete cleft lip and palate cases following maxillofacial orthopedics. I. The method and skeletal development from seven to thirteen years of age. Scand J Plast Reconstr Surg 1983;17:33-50. (Pubitemid 13013100)
56. Semb G, Shaw WC: Simonart's band and facial growth in unilateral clefts of the lip and palate. Cleft Palate Craniofac J 1991;28:40-48.
57. Roberts-Harry D, Semb G, Hathorn I, Killingback N: Facial growth in patients with unilateral clefts of the lip and palate: a two-center study. Cleft Palate Craniofac J 1996;33:489-493. (Pubitemid 26392815)
58. Da Silva Filho O, Santamaria M, Da Silva Dalben G, Semb G: Prevalence of a Simonart's band in patients with complete cleft lip and alveolus and complete cleft lip and palate. Cleft Palate Craniofac J 2006;43:442-445. (Pubitemid 44106842)
59. Rahimov F, Marazita ML, Visel A, Cooper ME, Hitchler MJ, Rubini M, Domann FE, Govil M, Christensen K, Bille C, Melbye M, Jugessur A, Lie RT, Wilcox AJ, Fitzpatrick DR, Green ED, Mossey PA, Little J, Steegers-Theunissen R P, Pennacchio LA, Schutte BC, Murray JC: Disruption of an AP-2α binding site in an IRF6 enhancer is associated with cleft lip. Nat Genet 2008;40:1341-1347.
60. Forrester MB, Merz RD, Yoon PW: Impact of prenatal diagnosis and elective termination on the prevalence of selected birth defects in Hawaii. Am J Epidemiol 1998;148:1206-1211. (Pubitemid 29018284)
61. Yazdy M, Honein M, Xing J: Reduction in orofacial clefts following folic acid fortification of the US grain supply. Birth Defects Res A Clin Mol Teratol 2007;79:16-23. (Pubitemid 46053406)
62. Mossey PA: Epidemiology underpinning research in the etiology of orofacial clefts. Orthod Craniofac Res 2007;10:114-120.
63. Hill L, Murphy M, McDowall M, Paul AH, et al: Maternal drug histories and congenital malformations: limb reduction defects and oral clefts. J Epidemiol Community Health 1988;42:1-7.
64. Shaw GM, Lammer EJ, Wasserman CR, et al: Risks of orofacial clefts in children born to women using multivitamins containing folic acid periconceptionally. Lancet 1995;346:393-396.
65. Czeizel AE, Timar L, Sarkozi A, et al: Dose-dependent effect of folic acid on the prevention of orofacial clefts. Pediatrics 1999;104:e66.
66. Kallen B: Maternal drug use and infant cleft lip/palate with special reference to corticoids. Cleft Palate Craniofac J 2003;40:624-628.
67. Van Rooij IA, Ocke MC, Straatman H, et al: Periconceptional folate intake by supplement and food reduces the risk of nonsyndromic cleft lip with or without cleft palate. Prev Med 2004;39:689-694. (Pubitemid 39194730)
68. Badovinac RL, Werler MM, Williams PL, Kelsey KT, Hayes C: Folic acid-containing supplement consumption during pregnancy and risk for oral clefts: a meta-analysis. Birth Defects Res A Clin Mol Teratol 2007;79:8-15. (Pubitemid 46053405)
69. Hayes C, Werler MM, Willett WC, et al: Case-control study of periconceptional folic acid supplementation and orofacial clefts. Am J Epidemiol 1996;143:1229-1234. (Pubitemid 26178735)
70. Krapels I P, van Rooij IA, Ocke MC, West CE, van der Horst CM, Steegers-Theunissen RP: Maternal nutritional status and the risk for orofacial cleft offspring in humans. J Nutr 2004;134:3106-3113. (Pubitemid 39470092)
71. Little J, Gilmour M, Mossey PA, Fitzpatrick D, Cardy A, Clayton-Smith J, Fryer AE: ITS MAGIC Collaboration. Folate and clefts of the lip and palate - a UKbased case-control study. Part I: Dietary and supplemental folate. Cleft Palate Craniofac J 2008;45:420-427.
72. Wong WY, Eskes TKAB, Kuijpers-Jagtman AM, Spauwen PHM, Steegers EAP, Thomas CMG, et al: Nonsyndromic orofacial clefts: association with maternal hyperhomocysteinemia. Teratology 1999;60:253-257. (Pubitemid 30265242)
73. Van Rooij IA, Vermeij-Keers C, Kluijtmans LA, et al: Does the interaction between maternal folate intake and the methylenetetrahydrofolate reductase polymorphisms affect the risk of cleft lip with or without cleft palate? Am J Epidemiol 2003;157:583-591. (Pubitemid 36368528)
74. Munger RG, Sauberlich HE, Corcoran C, Nepomuceno B, Daack-Hirsch S, Solon FS: Maternal vitamin B6 and folate status and risk of oral cleft birth defects in the Philippines. Birth Defects Res A Clin Mol Teratol 2004;70:464-471. (Pubitemid 38998795)
75. Little J, Gilmour M, Mossey PA, Fitzpatrick D, Cardy A, Clayton-Smith J, Hill A, Duthie SJ, Fryer AE, Molloy AM, Scott JM: ITS MAGIC Collaboration. Folate and clefts of the lip and palate - a UKbased case-control study. Part II: Biochemical and genetic analysis. Cleft Palate Craniofac J 2008;45:428-438.
76. Loffredo L, Souza JMP, Freitas JAS, Mossey PA: Oral clefts and vitamin supplementation. Cleft Palate Craniofac J 2000;37:69-76.
77. Itikala PR, Watkins ML, Mulinare J, Moore CA, Liu Y: Maternal multivitamin use and orofacial clefts in the offspring. Teratology 2001;63:79-86.
78. Simmons CJ, Mosley BS, Fulton-Bond CA, Hobbs CA: Birth defects in Arkansas: is folic acid fortification making a difference? Birth Defects Res A Clin Mol Teratol 2004;70:559-564. (Pubitemid 39244256)
79. Canfield MA, Collins JS, Botto LD, Williams LJ, Mai CT, Kirby RS, et al: Changes in the birth prevalence of selected birth defects after grain fortification with folic acid in the United States: findings from a multi-state population-based study. Birth Defects Res A Clin Mol Teratol 2005;73:679-689. (Pubitemid 41572010)
80. Ray JG, Meier C, Vermeulen MJ, Wyatt PR, Cole DE: Association between folic acid food fortification and congenital orofacial clefts. J Pediatr 2003;143:805-807. (Pubitemid 37510654)
81. López-Camelo JS, Orioli IM, da Graça Dutra M, Nazer-Herrera J, Rivera N, Ojeda ME, Canessa A, Wettig E, Fontannaz AM, Mellado C, Castilla EE: Reduction of birth prevalence rates of neural tube defects after folic acid fortification in Chile. Am J Med Genet A 2005;135:120-125. (Pubitemid 40769959)
82. Botto LD, Lisi A, Bower C, Canfield MA, Dattani N, De Vigan C, et al: Trends of selected malformations in relation to folic acid recommendations and fortification: an international assessment. Birth Defects Res A Clin Mol Teratol 2006;76:693-705. (Pubitemid 44655984)
83. Czeizel A, Sankaranarayanan K: The load of genetic and partly genetic disorders in man. Congenital anomalies: estimates of detriment in terms of life years lost and years of impairment. Mutat Res 1984;128:73-103. (Pubitemid 14052379)
84. Tennant PW, Pearce MS, Bythell M, Rankin J: Twenty-year survival of children born with congenital anomalies: a population-based study. Lancet 2010;375:649-656.
85. Christensen K, Juel K, Herskind AM, Murray JC: Long-term follow up study of survival associated with cleft lip and palate at birth. BMJ 2004;328:1405-1411.
86. Murthy J: Management of cleft lip and palate in adults. Indian J Plast Surg 2009;42:116-122.
87. Williams AC, Bearn D, Mildinhall S, Murphy T, Sell D, Shaw WC, Murray JJ, Sandy JR: Cleft lip and palate care in the United Kingdom - the Clinical Standards Advisory Group (CSAG) Study. Part 2: Dentofacial outcomes and patient satisfaction. Cleft Palate Craniofac J 2001;38:24-29. (Pubitemid 32436172)
88. Sell D, Grunwell P, Mildinhall S, Murphy T, Cornish TA, Bearn D, Shaw WC, Murray JJ, Williams AC, Sandy JR: Cleft lip and palate care in the United Kingdom - the Clinical Standards Advisory Group (CSAG) Study. Part 3: Speech outcomes. Cleft Palate Craniofac J 2001;38:30-37. (Pubitemid 32436173)
89. Ramana Y V, Nanda V, Biswas G, Chittoria R, Ghosh S, Sharma RK: Audiological profile in older children and adolescents with unrepaired cleft palate. Cleft Palate Craniofac J 2005;42:570-573. (Pubitemid 41346010)
90. Cotton RG: Rare disease registries and mutation/variation databases. Hum Mutat 2011;32:1073-1074.