Tolerability profile of clonidine in the treatment of adults with tourette syndrome

Clinical Neuropharmacology

Volumn 35, Issue 6, 2012, Pages 269-272

  Cavanna, Andrea Eugenio ^a,b   Selvini, Claudia ^a,c   Termine, Cristiano ^c   Balottin, Umberto ^d   Eddy, Clare M ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF INSUBRIA   (Italy)

^d UNIVERSITY OF PAVIA   (Italy)

Author keywords

adverse effects; clonidine; tics; tolerability; Tourette syndrome

Indexed keywords

ARIPIPRAZOLE; CLONAZEPAM; CLONIDINE; FLUOXETINE; HALOPERIDOL; MELATONIN; MIRTAZAPINE; PIMOZIDE; PSYCHOTROPIC AGENT; QUETIAPINE; RISPERIDONE; SERTRALINE; SULPIRIDE; ZONISAMIDE;

ACADEMIC ACHIEVEMENT; ADULT; ARTICLE; ATTENTION DEFICIT DISORDER; CLINICAL ARTICLE; COMORBIDITY; CONTROLLED STUDY; DISEASE SEVERITY; DIZZINESS; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; FEMALE; GASTROESOPHAGEAL REFLUX; GILLES DE LA TOURETTE SYNDROME; HEAD TINGLING; HEADACHE; HUMAN; INSOMNIA; IRRITABILITY; MALE; MENTAL CONCENTRATION; MUSCLE RIGIDITY; MUSCLE WEAKNESS; NEUROTOXICITY; OBSESSIVE COMPULSIVE DISORDER; OCULOGYRIC CRISIS; PREVALENCE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK FACTOR; SEDATION; SIDE EFFECT; SUICIDAL IDEATION; WEIGHT GAIN;

ADOLESCENT; ADRENERGIC ALPHA-2 RECEPTOR AGONISTS; ADULT; CHILD; CLONIDINE; COHORT STUDIES; FEMALE; HEADACHE; HUMANS; HYPNOTICS AND SEDATIVES; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; TOURETTE SYNDROME; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84870055923     PISSN: 03625664     EISSN: 1537162X     Source Type: Journal    
DOI: 10.1097/WNF.0b013e3182741c39     Document Type: Article

References (25)

1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorder, Text Revision (DSM-IV-TR). 4th ed. Washington, DC: APA; 2000.
2. Robertson MM. Gilles de la Tourette syndrome: the complexities of phenotype and treatment. Br J Hosp Med 2011;72:100-107.
3. Cavanna AE, Servo S, Monaco F, et al. The behavioral spectrum of Gilles de la Tourette syndrome. J Neuropsychiatry Clin Neurosci 2009;21:13-23.
4. Eddy CM, Rickards HE, Cavanna AE. Treatment strategies for tics in Tourette syndrome. Ther Adv Neurol Disord 2011;4:25-45.
5. Srour M, Lespèrance P, Richer F, et al. Pediatric psychopharmacology: psychopharmacology of tic disorders. J Can Acad Child Adolesc Psychiatry 2008;17:150-159.
6. The ESSTS Guidelines Group: Roessner V, Plesse KJ, Rothenberger A, et al. European clinical guidelines for Tourette syndrome and other tic disorders. Part II: pharmacological treatment. Eur Child Adolesc Psychiatry 2011;20:173-196.
7. Singer HS. Treatment of tics and Tourette syndrome. Current Treat Options Neurol 2010;12:539-561.
8. Shapiro AK, Shapiro E, Eisenkraft GJ. Treatment of Gilles de la Tourette's syndrome with clonidine and neuroleptics. Arch Gen Psychiatry 1983;40:1235-1240. (Pubitemid 13015020)
9. Leckman JF, Cohen DJ, Gertner JM, et al. Growth hormone response to clonidine in children ages 4-17: Tourette's syndrome vs children with short stature. J Am Acad Child Psychiatry 1984;23:174-181. (Pubitemid 14066110)
10. Singer HS, Gammon K, Quaskey S. Haloperidol, fluphenazine and clonidine in Tourette syndrome: controversies in treatment. Pediatr Neurosci 1985;12:71-74. (Pubitemid 16002737)
11. Singer HS, Brown J, Quaskey S, et al. The treatment of attention-deficit hyperactivity disorder in Tourette's syndrome: a double-blind placebo-controlled study with clonidine and desipramine. Pediatrics 1995;95:74-81.
12. Sandyk R. Tourette syndrome: successful treatment with clonidine and oxycodone. J Neurol 1986;233:178-179. (Pubitemid 16114601)
13. Jankovic J, Rohaidy H. Motor behavioural and pharmacologic findings in Tourette's syndrome. J Can Neurol Sci 1987;14:541-546. (Pubitemid 17147650)
14. Marsel-Mesulam M, Petersen RC. Treatment of Gilles de la Tourette's syndrome: eight-year, practice-based experience in a predominantly adult population. Neurology 1987;37:1828-1833. (Pubitemid 18026360)
15. Comings DE, Comings BG, Tacket T, et al. The clonidine patch and behaviour problems. J Am Acad Child Adolesc Psychiatry 1990;29:667-668.
16. Lichter DG, Jackson LA. Predictors of clonidine response in Tourette syndrome: implications and inferences. J Child Neurol 1996;11:93-97. (Pubitemid 26098132)
17. Gancher S, Conant-Norville D, Angell R. Treatment of Tourette's syndrome with transdermal clonidine: a pilot study. J Neuropsychiatry Clin Neurosci 1990;2:66-69. (Pubitemid 20125847)
18. Kessler AR. Clonidine treatment increases tics in patients with Tourette syndrome: case report. J Child Neurol 2001;16:380-381. (Pubitemid 32547307)
19. Leckman JF, Cohen DJ, Detlor J, et al. Clonidine in the treatment of Tourette syndrome: a review of data. Adv Neurol 1982;35:391-401.
20. Robertson MM, Eapen V. The National Hospital interview schedule for the assessment of Giles de la Tourette syndrome. Int J Methods Psychiatr Res 1996;6:203-226. (Pubitemid 127757465)
21. The Tourette's Syndrome Study Group. Treatment of ADHD in children with tics. A randomized controlled trial. Neurology 2002;58:527-536.
22. Du Y, Li H, Vance A, et al. Randomized double-blind multicentre placebo-controlled clinical trial of the clonidine adhesive patch for the treatment of tic disorders. Aus N Z J Psych 2008;42:807-813.
23. Leckman JF, Detlor J, Harcherik DF, et al. Acute and chronic clonidine treatment in Tourette's syndrome: a preliminary report on clinical response and effect on plasma and urinary catecholamine metabolites, growth hormone, and blood pressure. J Am Acad Child Psychiatry 1983;22:433-440. (Pubitemid 14037826)
24. Leckman JF, Hardin MT, Riddle MA, et al. Clonidine treatment of Gilles de la Tourette syndrome. Arch Gen Psychiatry 1991;48:324-328.
25. Gaffney GR, Perry PJ, Lund BC, et al. Risperidone versus clonidine in the treatment of children and adolescents with Tourette's syndrome. J Am Acad Child Adolesc Psychiatry 2002;41:330-336. (Pubitemid 38338155)