Hormone receptor expression in invasive breast cancer among korean women and comparison of 3 antiestrogen receptor antibodies: A multi-institutional retrospective study using tissue microarrays

American Journal of Surgical Pathology

Volumn 36, Issue 12, 2012, Pages 1817-1825

  Bae, Young Kyung ^a   Gong, Gyungyub ^b   Kang, Jun ^c   Lee, Ahwon ^d   Cho, Eun Yoon ^e   Lee, Ji Shin ^f   Suh, Kwang Sun ^g   Lee, Dong Wha ^h  

^a Yeungnam University College of Medicine   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

^c Inje University College of Medicine   (South Korea)

^d The Catholic University of Korea College of Medicine   (South Korea)

^e Sungkyunkwan University School of Medicine   (South Korea)

^f Chonnam National University Medical School   (South Korea)

^g Chungnam National University College of Medicine   (South Korea)

^h Soonchunhyang University College of Medicine   (South Korea)

Author keywords

6F11 and SP1); breast cancer; ER (1D5; PR (1E2)

Indexed keywords

ANTIBODY; DIAGNOSTIC AGENT; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; TUMOR MARKER;

ADULT; AGED; ANTIBODY SPECIFICITY; ARTICLE; BREAST TUMOR; CANCER INVASION; CARCINOMA; CHEMISTRY; CHI SQUARE DISTRIBUTION; COMPARATIVE STUDY; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; KAPLAN MEIER METHOD; MIDDLE AGED; MORTALITY; MULTICENTER STUDY; PATHOLOGY; PREDICTIVE VALUE; PROGNOSIS; RETROSPECTIVE STUDY; SOUTH KOREA; TIME; TISSUE MICROARRAY;

ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES; ANTIBODY SPECIFICITY; BREAST NEOPLASMS; CARCINOMA; CHI-SQUARE DISTRIBUTION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; MIDDLE AGED; NEOPLASM INVASIVENESS; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; REPUBLIC OF KOREA; RETROSPECTIVE STUDIES; TIME FACTORS; TISSUE ARRAY ANALYSIS; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 84870025635     PISSN: 01475185     EISSN: 15320979     Source Type: Journal    
DOI: 10.1097/PAS.0b013e318267b012     Document Type: Article

References (15)

1. Hammond ME, Hayes DF, Dowsett M, et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer. J Clin Oncol. 2010;28:2784-2795.
2. Lee A, Gong G, Park K, et al. A Multi-institutional study of interlaboratory variance in the estrogen and progesterone receptor assays. J Breast Cancer. 2010;13:46-52.
3. Kim MJ, Ro JY, Ahn SH, et al. Clinicopathologic significance of the basal-like subtype of breast cancer: a comparison with hormone receptor and Her2/neu-overexpressing phenotypes. Hum Pathol. 2006;37:1217-1226.
4. Allred DC, Harvey JM, Berardo M, et al. Prognostic and predictive factors in breast cancer by immunohistochemical analysis. Mod Pathol. 1998;11:155-168.
5. Lee KM, Choi JY, Kang C, et al. Genetic polymorphisms of selected DNA repair genes, estrogen and progesterone receptor status, and breast cancer risk. Clin Cancer Res. 2005;11:4620-4626.
6. Park SH, Kim H, Song BJ. Down regulation of bcl2 expression in invasive ductal carcinomas is both estrogen-and progesterone-receptor dependent and associated with poor prognostic factors. Pathol Oncol Res. 2002;8:26-30.
7. Cheang MC, Treaba DO, Speers CH, et al. Immunohistochemical detection using the new rabbit monoclonal antibody SP1 of estrogen receptor in breast cancer is superior to mouse monoclonal antibody 1D5 in predicting survival. J Clin Oncol. 2006;24:5637-5644.
8. Grabau D, Bendahl PO, Ryden L, et al. Three different antibodies for estrogen receptor analysis in breast cancer-implications for positive frequency, reproducibility and clinical outcome. Eur J Cancer (Suppl). 2010;8:103.
9. Nadji M, Gomez-Fernandez C, Ganjei-Azar P, et al. Immunohis-tochemistry of estrogen and progesterone receptors reconsidered: experience with 5, 993 breast cancers. Am J Clin Pathol. 2005;123:21-27.
10. Huang Z, Zhu W, Szekeres G, et al. Development of new rabbit monoclonal antibody to estrogen receptor: immunohistochemical assessment on formalin-fixed, paraffin-embedded tissue sections. Appl Immunohistochem Mol Morphol. 2005;13:91-95.
11. Kaplan PA, Frazier SR, Loy TS, et al. 1D5 and 6F11: An immunohistochemical comparison of two monoclonal antibodies for the evaluation of estrogen receptor status in primary breast carcinoma. Am J Clin Pathol. 2005;123:276-280.
12. Harvey JM, Clark GM, Osborne CK, et al. Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer. J Clin Oncol. 1999;17:1474-1481.
13. Layfield LJ, Saria E, Mooney EE, et al. Tissue heterogeneity of immunohistochemically detected estrogen receptor. Implications for image analysis quantification. Am J Clin Pathol. 1998;110:758-764.
14. Collins LC, Botero ML, Schnitt SJ. Bimodal frequency distribution of estrogen receptor immunohistochemical staining results in breast cancer: an analysis of 825 cases. Am J Clin Pathol. 2005;123:16-20.
15. Schnitt SJ. Estrogen receptor testing of breast cancer in current clinical practice: What's the question? J Clin Oncol. 2006;24:1797-1799.