The roles of glutathione, glutathione peroxidase, glutathione reductase and the carbonyl protein in pulmonary and extra pulmonary tuberculosis

Journal of Clinical and Diagnostic Research

Volumn 6, Issue 9, 2012, Pages 1462-1465

  Dalvi, Shubhangi M ^a   Patil, Vinayak W ^a   Ramraje, Nagsen N ^a  

^a GRANT MEDICAL COLLEGE   (India)

Author keywords

Carbonyl protein content; Glutathione; GSH Px; GSH Rx; Tuberculosis

Indexed keywords

CARBONYL PROTEIN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; PROTEIN; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE CLASSIFICATION; ENZYME BLOOD LEVEL; EXTRAPULMONARY TUBERCULOSIS; FEMALE; HUMAN; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; OXIDATIVE STRESS; PROTEIN BLOOD LEVEL; SPUTUM ANALYSIS; SPUTUM CULTURE; TREATMENT DURATION;

EID: 84870016138     PISSN: 2249782X     EISSN: 0973709X     Source Type: Journal    
DOI: 10.7860/JCDR/2012/4410.2533     Document Type: Article

References (20)

1. Flynn JL, Chan J. Immunology of tuberculosis. Annu. Rev. Immunol 2001; 19: 93-129.
2. Chevion M, Berenshtein E, Stadtman ER. Human studies related to protein oxidation: protein carbonyl content as a marker of damage. Free Radic Res. 2000; 33: 99-108.
3. Castegna A, Drake J. Methods in biological oxidative stress, carbonyl protein levels-An assessment of protein oxidation. Methods inPharmacology and Toxicology 2003; 3:161-68.
4. Barbara S, Berlett Earl R, Stadtman S. Protein oxidation in aging, disease and oxidative stress. The Journal of Biological Chemistry 1997; 272(15): 20313-16.
5. Meister A. Methods in Systems Biology. Methods in Enzymology 1995;251: 3-7.1464
6. Hafeman DG, Sunde RA, Hoekstra WG. Effect of dietary selenium on erythrocyte and liver glutathione peroxidase in the rat J. Nutr. 1974;104:580-87.
7. Chu FF. The human glutathione peroxidase genes GPX2, GPX3, and GPX4 map to chromosomes 14, 5, and 19, respectively. CytogenetCell Genet 1994; 66 (2):96-98.
8. Carranza C, Juarez E, Torres M, Mycobacterium tuberculosis growth control by lung macrophages and CD8 cells from patient contacts. Am J Resp Crit Care Medicine 2006; 173: 238-45.
9. Levine RL, Garland D. Determination of carbonyl content in oxidatively modified proteins. Methods in Enzymology 1990; 186, 464-78.
10. Beutler E, et al. Improved method for the determination of bloodglutathione. J Lab Clin Med 1963; 61: 882-90.
11. Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. Lab Clin Med 1967: 158-69.
12. Goldberg DM, Spooner RJ. Method for the determination of glutathione reductase. Methods of Enzymatic Analysis 1983; 3 (3): 258-65.
13. Drancourt M, Raoult D. Palaeomicrobiology: current issues andperspectives. Nature Review Microbiology 2005; 3: 23-35.
14. Khan MA, Tania M, Zhang D, Chen H. Antioxidant enzymes and cancer. Chin J Cancer Res 2010; 22 (2): 87-92.
15. Hipkiss AR. Carnosine and protein carbonyl groups: A possible relationship. Biochemistry 2000; 65 (7): 907-16.
16. Kulkarni A, Madrasi NA. Relationship of nitric oxide and protein carbonyl in tuberculosis. Indian J Tuberc. 2008; 55(3):138-44.
17. Reddy YN, Murthy SV, Krishna DR, Prabhakar MC. Role of freeradicals and antioxidants in tuberculosis patients. Indian J tuberc 2004; 51:213-18.
18. Vijayamalini M, Manoharan S. Lipid peroxidation, Vitamins C, E and reduced glutathione levels in patients with pulmonary tuberculosis. Cell Biochem Funct 2004; 22:19-22.
19. Andrade JA, Crow JP. Protein nitration, metabolites of reactive nitrogen species and inflammation in lung allografts. Am J Respir Crit Care Med 2000; 161(6): 2035-42.
20. Connolly LE, Edelstein PH, Ramakrishnan L. Why is long-term therapy required to cure tuberculosis? PLOS Medicine 2007; 4: e120.