-
1
-
-
48249125791
-
Malignant gliomas in adults
-
Wen PY, Kesari S. Malignant gliomas in adults. N Engl J Med 2008;359:492-507.
-
(2008)
N Engl J Med
, vol.359
, pp. 492-507
-
-
Wen, P.Y.1
Kesari, S.2
-
2
-
-
79958165458
-
A distinct region of the MGMT CpGisland critical for transcriptional regulation is preferentially methylated in glioblastoma cells and xenografts
-
Malley DS, Hamoudi RA, Kocialkowski S, Pearson DM, Collins VP, Ichimura K. A distinct region of the MGMT CpGisland critical for transcriptional regulation is preferentially methylated in glioblastoma cells and xenografts. ActaNeuropathol 2011;121:651-61.
-
(2011)
ActaNeuropathol
, vol.121
, pp. 651-661
-
-
Malley, D.S.1
Hamoudi, R.A.2
Kocialkowski, S.3
Pearson, D.M.4
Collins, V.P.5
Ichimura, K.6
-
3
-
-
37449003812
-
Nomograms for predicting survival of patients with newly diagnosed glioblastoma: Prognostic factor analysis of EORTC and NCIC trial 26981-22981/CE.3
-
Gorlia T, Van Den Bent MJ, Hegi ME, Mirimanoff RO, Weller M, Cairncross JG, et al. Nomograms for predicting survival of patients with newly diagnosed glioblastoma: Prognostic factor analysis of EORTC and NCIC trial 26981-22981/CE.3. Lancet Oncol 2008;9:29-38.
-
(2008)
Lancet Oncol
, vol.9
, pp. 29-38
-
-
Gorlia, T.1
Van Den Bent, M.J.2
Hegi, M.E.3
Mirimanoff, R.O.4
Weller, M.5
Cairncross, J.G.6
-
4
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
-
Stupp R, Hegi ME, Mason WP, Van Den Bent MJ, Taphoorn MJ, Janzer RC, et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 2009;10:459-66.
-
(2009)
Lancet Oncol
, vol.10
, pp. 459-466
-
-
Stupp, R.1
Hegi, M.E.2
Mason, W.P.3
Van Den Bent, M.J.4
Taphoorn, M.J.5
Janzer, R.C.6
-
5
-
-
78650035002
-
DNA methylation in glioblastoma: Impact on gene expression and clinical outcome
-
Etcheverry A, Aubry M, De Tayrac M, Vauleon E, Boniface R, Guenot F, et al. DNA methylation in glioblastoma: Impact on gene expression and clinical outcome. BMC Genomics 2010;11:701.
-
(2010)
BMC Genomics
, vol.11
, pp. 701
-
-
Etcheverry, A.1
Aubry, M.2
De Tayrac, M.3
Vauleon, E.4
Boniface, R.5
Guenot, F.6
-
6
-
-
34248212690
-
Methylguaninemethyltransferase testing in glioblastoma: When and how?
-
Stupp R, Hegi ME. Methylguaninemethyltransferase testing in glioblastoma: When and how? J ClinOncol 2007;25:1459-60.
-
(2007)
J ClinOncol
, vol.25
, pp. 1459-1460
-
-
Stupp, R.1
Hegi, M.E.2
-
7
-
-
79251536531
-
Comprehensive analysis of MGMT promoter methylation: Correlation with MGMT expression and clinical response in GBM
-
Shah N, Lin B, Sibenaller Z, Ryken T, Lee H, Yoon JG, et al. Comprehensive analysis of MGMT promoter methylation: Correlation with MGMT expression and clinical response in GBM. PLoS One 2011;6:e16146.
-
(2011)
PLoS One
, vol.6
-
-
Shah, N.1
Lin, B.2
Sibenaller, Z.3
Ryken, T.4
Lee, H.5
Yoon, J.G.6
-
8
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi ME, Diserens AC, Gorlia T, Hamou MF, De Tribolet N, Weller M, et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 2005;352:997-1003.
-
(2005)
N Engl J Med
, vol.352
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
Hamou, M.F.4
De Tribolet, N.5
Weller, M.6
-
9
-
-
38149046589
-
Pitfalls in the assessment of MGMT expression and in its correlation with survival in diffuse astrocytomas: Proposal of a feasible immunohistochemical approach
-
Capper D, Mittelbronn M, Meyermann R, Schittenhelm J. Pitfalls in the assessment of MGMT expression and in its correlation with survival in diffuse astrocytomas: Proposal of a feasible immunohistochemical approach. ActaNeuropathol 2008;115:249-59.
-
(2008)
ActaNeuropathol
, vol.115
, pp. 249-259
-
-
Capper, D.1
Mittelbronn, M.2
Meyermann, R.3
Schittenhelm, J.4
-
10
-
-
33746860420
-
O6-methylguanine-DNA methyltransferase expression strongly correlates with outcome in childhood malignant gliomas: Results from the CCG-945 Cohort
-
Pollack IF, Hamilton RL, Sobol RW, Burnham J, Yates AJ, Holmes EJ, et al. O6-methylguanine-DNA methyltransferase expression strongly correlates with outcome in childhood malignant gliomas: Results from the CCG-945 Cohort. J Clin Oncol 2006;24:3431-7.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3431-3437
-
-
Pollack, I.F.1
Hamilton, R.L.2
Sobol, R.W.3
Burnham, J.4
Yates, A.J.5
Holmes, E.J.6
-
11
-
-
78650510699
-
O6-methylguanine DNA methyltransferase gene promoter methylation status in gliomas and its correlation with other molecular alterations: First Indian report with review of challenges for use in customized treatment
-
Jha P, Suri V, Jain A, Sharma MC, Pathak P, Srivastava A, et al. O6-methylguanine DNA methyltransferase gene promoter methylation status in gliomas and its correlation with other molecular alterations: First Indian report with review of challenges for use in customized treatment. Neurosurgery 2010;67:1681-91.
-
(2010)
Neurosurgery
, vol.67
, pp. 1681-1691
-
-
Jha, P.1
Suri, V.2
Jain, A.3
Sharma, M.C.4
Pathak, P.5
Srivastava, A.6
-
12
-
-
78649326720
-
MGMT gene promoter methylation in pediatric glioblastomas
-
Srivastava A, Jain A, Jha P, Suri V, Sharma MC, Mallick S, et al. MGMT gene promoter methylation in pediatric glioblastomas. Childs Nerv Syst 2010;26:1613-8.
-
(2010)
Childs Nerv Syst
, vol.26
, pp. 1613-1618
-
-
Srivastava, A.1
Jain, A.2
Jha, P.3
Suri, V.4
Sharma, M.C.5
Mallick, S.6
-
13
-
-
34547122001
-
The 2007 WHO classification of tumours of the central nervous system
-
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 2007;114:97-109.
-
(2007)
Acta Neuropathol
, vol.114
, pp. 97-109
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
Cavenee, W.K.4
Burger, P.C.5
Jouvet, A.6
-
14
-
-
0034326238
-
Predicting lung cancer by detecting aberrant promoter methylation in sputum
-
Palmisano WA, Divine KK, Saccomanno G, Gilliland FD, Baylin SB, Herman JG, et al. Predicting lung cancer by detecting aberrant promoter methylation in sputum. Cancer Res 2000;60:5954-8.
-
(2000)
Cancer Res
, vol.60
, pp. 5954-5958
-
-
Palmisano, W.A.1
Divine, K.K.2
Saccomanno, G.3
Gilliland, F.D.4
Baylin, S.B.5
Herman, J.G.6
-
15
-
-
0033557903
-
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
-
Esteller M, Hamilton SR, Burger PC, Baylin SB, Herman JG. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res 1999;59:793-7.
-
(1999)
Cancer Res
, vol.59
, pp. 793-797
-
-
Esteller, M.1
Hamilton, S.R.2
Burger, P.C.3
Baylin, S.B.4
Herman, J.G.5
-
16
-
-
34548147443
-
Optimization of quantitative MGMT promoter methylation analysis using pyrosequencing and combined bisulfite restriction analysis
-
Mikeska T, Bock C, El-Maarri O, Hubner A, Ehrentraut D, Schramm J, et al. Optimization of quantitative MGMT promoter methylation analysis using pyrosequencing and combined bisulfite restriction analysis. J MolDiagn 2007;9:368-81.
-
(2007)
J MolDiagn
, vol.9
, pp. 368-381
-
-
Mikeska, T.1
Bock, C.2
El-Maarri, O.3
Hubner, A.4
Ehrentraut, D.5
Schramm, J.6
-
17
-
-
35649001325
-
Intratumoral homogeneity of MGMT promoter hypermethylation as demonstrated in serial stereotactic specimens from anaplastic astrocytomas and glioblastomas
-
Grasbon-Frodl EM, Kreth FW, Ruiter M, Schnell O, Bise K, Felsberg J, et al. Intratumoral homogeneity of MGMT promoter hypermethylation as demonstrated in serial stereotactic specimens from anaplastic astrocytomas and glioblastomas. Int J Cancer 2007;121:2458-64.
-
(2007)
Int J Cancer
, vol.121
, pp. 2458-2464
-
-
Grasbon-Frodl, E.M.1
Kreth, F.W.2
Ruiter, M.3
Schnell, O.4
Bise, K.5
Felsberg, J.6
-
18
-
-
0025195404
-
Mammalian O6-alkylguanine-DNA alkyltransferase: Regulation and importance in response to alkylating carcinogenic and therapeutic agents
-
Pegg AE. Mammalian O6-alkylguanine-DNA alkyltransferase: Regulation and importance in response to alkylating carcinogenic and therapeutic agents. Cancer Res 1990;50:6119-29.
-
(1990)
Cancer Res
, vol.50
, pp. 6119-6129
-
-
Pegg, A.E.1
-
19
-
-
0030823671
-
Methylation hot spots in the 5'OElig; flanking region denote silencing of the O6-methylguanine-DNA methyltransferase gene
-
Qian XC, Brent TP. Methylation hot spots in the 5'OElig; flanking region denote silencing of the O6-methylguanine-DNA methyltransferase gene. Cancer Res 1997;57:3672-7.
-
(1997)
Cancer Res
, vol.57
, pp. 3672-3677
-
-
Qian, X.C.1
Brent, T.P.2
-
20
-
-
75149166496
-
MGMT promoter methylation in malignant gliomas: Ready for personalized medicine?
-
Weller M, Stupp R, Reifenberger G, Brandes AA, Van Den Bent MJ, Wick W, et al. MGMT promoter methylation in malignant gliomas: Ready for personalized medicine? Nat Rev Neurol 2009;6:39-51.
-
(2009)
Nat Rev Neurol
, vol.6
, pp. 39-51
-
-
Weller, M.1
Stupp, R.2
Reifenberger, G.3
Brandes, A.A.4
Van Den Bent, M.J.5
Wick, W.6
-
21
-
-
78650018623
-
The next generation of glioma biomarkers: MGMT methylation, BRAF fusions and IDH1 mutations
-
Von Deimling A, Korshunov A, Hartmann C. The next generation of glioma biomarkers: MGMT methylation, BRAF fusions and IDH1 mutations. Brain Pathol 2010;21:74-87.
-
(2010)
Brain Pathol
, vol.21
, pp. 74-87
-
-
Von Deimling, A.1
Korshunov, A.2
Hartmann, C.3
-
22
-
-
79251577095
-
O6-Methylguanine-DNA methyltransferase protein expression by immunohistochemistry in brain and non-brain systemic tumors: Systematic review and meta-analysis of correlation with methylation-specific polymerase chain reaction
-
Brell M, Ibanez J, Tortosa A. O6-Methylguanine-DNA methyltransferase protein expression by immunohistochemistry in brain and non-brain systemic tumors: Systematic review and meta-analysis of correlation with methylation-specific polymerase chain reaction. BMC Cancer 2011;11:35.
-
(2011)
BMC Cancer
, vol.11
, pp. 35
-
-
Brell, M.1
Ibanez, J.2
Tortosa, A.3
-
23
-
-
51249098488
-
Anti O6-Methylguanine-DNA methyltransferase (MGMT) immunohistochemistry in glioblastomamultiforme: Observor variability and lack of association with patient survival impede its use as clinical biomarker
-
Preusser M, Charles JR, Felsberg J, Reifenberg G, Hamou MF, Diserens AC, et al. Anti O6-Methylguanine-DNA methyltransferase (MGMT) immunohistochemistry in glioblastomamultiforme: Observor variability and lack of association with patient survival impede its use as clinical biomarker. Brain Pathol 2008;18:520-32.
-
(2008)
Brain Pathol
, vol.18
, pp. 520-532
-
-
Preusser, M.1
Charles, J.R.2
Felsberg, J.3
Reifenberg, G.4
Hamou, M.F.5
Diserens, A.C.6
-
24
-
-
77953291279
-
Prognostic of O6-Methylguanine-DNA methyltransferase status in glioblastoma patients assessed by five different methods
-
Karayan-Tapon L, Quillen V, Guilhot J, Wager M, Fromont G, Sailali S, et al. Prognostic of O6-Methylguanine-DNA methyltransferase status in glioblastoma patients assessed by five different methods. J Neurooncol 2010;97:311-22.
-
(2010)
J Neurooncol
, vol.97
, pp. 311-322
-
-
Karayan-Tapon, L.1
Quillen, V.2
Guilhot, J.3
Wager, M.4
Fromont, G.5
Sailali, S.6
-
25
-
-
63449115574
-
MGMT analysis at DNA, RNA and protein levels in glioblastoma tissue
-
Preusser M. MGMT analysis at DNA, RNA and protein levels in glioblastoma tissue. Histol Histopathol 2009;24:511-8.
-
(2009)
Histol Histopathol
, vol.24
, pp. 511-518
-
-
Preusser, M.1
-
26
-
-
54849188000
-
Relevance of MSP assay for the detection of MGMT promoter hypermethylation in glioblastomas
-
Yachi K, Watanabe T, Ohta T, Fukushima T, Yoshino A, Ogino A, et al. Relevance of MSP assay for the detection of MGMT promoter hypermethylation in glioblastomas. Int J Oncol 2008;33:469-75.
-
(2008)
Int J Oncol
, vol.33
, pp. 469-475
-
-
Yachi, K.1
Watanabe, T.2
Ohta, T.3
Fukushima, T.4
Yoshino, A.5
Ogino, A.6
-
27
-
-
11144349554
-
Frequent promoter hypermethylation and low expression of the MGMT gene in oligodendroglial tumors
-
Mollemann M, Wolter M, Felsberg J, Collins VP, Reifenberger G. Frequent promoter hypermethylation and low expression of the MGMT gene in oligodendroglial tumors. Int J Cancer 2005;113:379-85.
-
(2005)
Int J Cancer
, vol.113
, pp. 379-385
-
-
Mollemann, M.1
Wolter, M.2
Felsberg, J.3
Collins, V.P.4
Reifenberger, G.5
-
28
-
-
33947536116
-
A simplified laboratory validated assay for MGMT promoter hypermethylation analysis of glioma specimens from formalin-fixed paraffin-embedded tissue
-
Cankovic M, Mikkelsen T, Rosenblum ML, Zarbo RJ. A simplified laboratory validated assay for MGMT promoter hypermethylation analysis of glioma specimens from formalin-fixed paraffin-embedded tissue. Lab Invest 2007;87:392-7.
-
(2007)
Lab Invest
, vol.87
, pp. 392-397
-
-
Cankovic, M.1
Mikkelsen, T.2
Rosenblum, M.L.3
Zarbo, R.J.4
-
29
-
-
3042682951
-
Histological indicators of prognosis in glioblastomas: Retinoblastoma protein expression and oligodendroglial differentiation indicate improved survival
-
Hilton DA, Penney M, Pobereskin L, Sanders H, Love S. Histological indicators of prognosis in glioblastomas: Retinoblastoma protein expression and oligodendroglial differentiation indicate improved survival. Histopathology 2004;44:555-60.
-
(2004)
Histopathology
, vol.44
, pp. 555-560
-
-
Hilton, D.A.1
Penney, M.2
Pobereskin, L.3
Sanders, H.4
Love, S.5
-
30
-
-
33748533494
-
Correlation among pathology, genotype, and patient outcomes in glioblastoma
-
Homma T, Fukushima T, Vaccarella S, Yonekawa Y, Di Patre PL, Franceschi S, et al. Correlation among pathology, genotype, and patient outcomes in glioblastoma. J Neuropathol Exp Neurol 2006;65:846-54.
-
(2006)
J Neuropathol Exp Neurol
, vol.65
, pp. 846-854
-
-
Homma, T.1
Fukushima, T.2
Vaccarella, S.3
Yonekawa, Y.4
Di Patre, P.L.5
Franceschi, S.6
-
31
-
-
67650462247
-
Cerebral glioblastoma with oligodendrogliomal component: Analysis of 36 cases
-
Salvati M, Formichella AI, D'Elia A, Brogna C, Frati A, Giangaspero F, et al. Cerebral glioblastoma with oligodendrogliomal component: Analysis of 36 cases. J Neurooncol 2009;94:129-34.
-
(2009)
J Neurooncol
, vol.94
, pp. 129-134
-
-
Salvati, M.1
Formichella, A.I.2
D'Elia, A.3
Brogna, C.4
Frati, A.5
Giangaspero, F.6
-
32
-
-
42549170131
-
Glioblastomas: Correlation between oligodendroglial components, genetic abnormalities, and prognosis
-
Pinto LW, Araujo MB, Vettore AL, Wernersbach L, Leite AC, Chimelli L, et al. Glioblastomas: Correlation between oligodendroglial components, genetic abnormalities, and prognosis. Virchows Arch 2008;452:481-90.
-
(2008)
Virchows Arch
, vol.452
, pp. 481-490
-
-
Pinto, L.W.1
Araujo, M.B.2
Vettore, A.L.3
Wernersbach, L.4
Leite, A.C.5
Chimelli, L.6
-
33
-
-
79952277565
-
Glioblastomas with oligodendroglial component - Common origin of the different histological parts and genetic subclassification
-
Klink B, Schlingelhof B, Klink M, Stout-Weider K, Patt S, Schrock E. Glioblastomas with oligodendroglial component - common origin of the different histological parts and genetic subclassification. Anal Cell Pathol (Amst) 2010;33:37-54.
-
(2010)
Anal Cell Pathol (Amst)
, vol.33
, pp. 37-54
-
-
Klink, B.1
Schlingelhof, B.2
Klink, M.3
Stout-Weider, K.4
Patt, S.5
Schrock, E.6
|