Statin upregulates the expression of klotho, an anti-aging gene, in experimental cyclosporine nephropathy

Nephron - Experimental Nephrology

Volumn 120, Issue 4, 2012, Pages

  Yoon, Hye Eun ^a   Lim, Sun Woo ^b   Piao, Shang Guo ^b   Song, Ji Hyun ^b   Kim, Jin ^a   Yang, Chul Woo ^a,b  

^a The Catholic University of Korea   (South Korea)

^b The Catholic University of Korea   (South Korea)

Author keywords

Apoptosis; Cyclosporine nephrotoxicity; Oxidative stress; Renal transplantation; Statin

Indexed keywords

BIM PROTEIN; CYCLOSPORIN A; HEME OXYGENASE 1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; KLOTHO PROTEIN; MANGANESE SUPEROXIDE DISMUTASE; PRAVASTATIN; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR FOXO; BETA GLUCURONIDASE; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; GENE; GENE EXPRESSION REGULATION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; KIDNEY DISEASE; KLOTHO GENE; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; AGING; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; KIDNEY; METABOLISM; PHYSIOLOGY; UPREGULATION;

AGING; ANIMALS; CYCLOSPORINE; GLUCURONIDASE; IMMUNOSUPPRESSIVE AGENTS; KIDNEY; KIDNEY DISEASES; MALE; MICE; PRAVASTATIN; UP-REGULATION;

EID: 84869884299     PISSN: None     EISSN: 16602129     Source Type: Journal    
DOI: 10.1159/000342117     Document Type: Article

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