Effects of N-Butylscopolammonium Bromide on Lung Function in Horses with Recurrent Airway Obstruction

Journal of Veterinary Internal Medicine

Volumn 26, Issue 6, 2012, Pages 1433-1438

  Couetil, L ^a   Hammer, J ^a   Miskovic Feutz, M ^a   Nogradi, N ^a   Perez Moreno, C ^a   Ivester, K ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

Anticholinergic therapy; Bronchodilatation; Heaves; RAO

Indexed keywords

CHOLINERGIC RECEPTOR BLOCKING AGENT; SCOPOLAMINE BUTYL BROMIDE;

ANIMAL; ANIMAL DISEASE; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; HORSE; HORSE DISEASE; RANDOMIZED CONTROLLED TRIAL;

ANIMALS; BUTYLSCOPOLAMMONIUM BROMIDE; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; HORSE DISEASES; HORSES; LUNG DISEASES, OBSTRUCTIVE; PARASYMPATHOLYTICS;

ANIMALIA; EQUIDAE;

EID: 84869882873     PISSN: 08916640     EISSN: 19391676     Source Type: Journal    
DOI: 10.1111/j.1939-1676.2012.00992.x     Document Type: Article

References (24)

1. Derksen FJ, Robinson NE, Armstrong PJ, et al. Airway reactivity in ponies with recurrent airway obstruction (heaves). J Appl Physiol 1985;58:598-604.
2. Couëtil LL, Rosenthal FS, DeNicola DB, Chilcoat CD. Clinical signs, evaluation of bronchoalveolar lavage fluid, and assessment of pulmonary function in horses with inflammatory respiratory disease. Am J Vet Res 2001;62:538-546.
3. Leclere M, Lavoie-Lamoureux A, Lavoie JP. Heaves, an asthma-like disease of horses. Respirology 2011;16:1027-1046.
4. McGorum BC, Dixon PM, Halliwell RE. Responses of horses affected with chronic obstructive pulmonary disease to inhalation challenges with mould antigens. Equine Vet J 1993;25:261-267.
5. Gillespie JR, Tyler WS, Eberly VE. Pulmonary ventilation and resistance in emphysematous and control horses. J Appl Physiol 1966;21:416-422.
6. Tesarowski DB, Viel L, McDonell WN. Pulmonary function measurements during repeated environmental challenge of horses with recurrent airway obstruction (heaves). Am J Vet Res 1996;57:1214-1219.
7. Robinson NE, Derksen FJ, Berney C, Goosens L. The airway response of horses with recurrent airway obstruction (heaves) to aerosol administration of ipratropium bromide. Equine Vet J 1993;25:299-303.
8. Pearson EG, Riebold TW. Comparison of bronchodilators in alleviating clinical signs in horses with chronic obstructive pulmonary disease. J Am Vet Med Assoc 1989;194:1287-1291.
9. Ducharme NG, Fubini SL. Gastrointestinal complications associated with the use of atropine in horses. J Am Vet Med Assoc 1983;182:229-231.
10. Roelvink ME, Goossens L, Kalsbeek HC, Wensing T. Analgesic and spasmolytic effects of dipyrone, hyoscine-N-butylbromide and a combination of the two in ponies. Vet Rec 1991;129:378-380.
11. Geimer TR, Ekström PM, Ludders JW, et al. Haemodynamic effects of hyoscine-N-butylbromide in ponies. J Vet Pharmacol Ther 1995;18:13-16.
12. Rush BR, Raub ES, Rhoads WS, et al. Pulmonary function in horses with recurrent airway obstruction after aerosol and parenteral administration of beclomethasone dipropionate and dexamethasone, respectively. Am J Vet Res 1998;59:1039-1043.
13. Murphy JR, McPherson EA, Dixon PM. Chronic obstructive pulmonary disease (COPD): Effects of bronchodilator drugs on normal and affected horses. Equine Vet J 1980;12:10-14.
14. Duvivier DH, Votion D, Vandenput S, et al. Airway response of horses with COPD to dry powder inhalation of ipratropium bromide. Vet J 1997;154:149-153.
15. Bertin FR, Ivester KM, Couëtil LL. Comparative efficacy of inhaled albuterol between two hand-held delivery devices in horses with recurrent airway obstruction. Equine Vet J 2011;43:393-398.
16. Art T, Moffarts BD, Erck EV, et al. Effets fonctionnels respiratoires induits par l'inhalation de glycopyrrolate chez le cheval poussif en crise. Annales De Medicine Veterinaire 2003;147:175-180.
17. Brown JH, Taylor P. Muscarinic receptor agonists and antagonists. In: Hardman JG, Limbird LE, eds. Goodman & Gilman's The Pharmacological Basis of Therapeutics, 10th ed. New York: McGraw-Hill; 2001:155-173.
18. Dyde R, Chapman AH, Gale R, et al. Precautions to be taken by radiologists and radiographers when prescribing hyoscine-N-butylbromide. Clin Radiol 2008;63:739-743.
19. Davies JV, Gerring EL. Effect of spasmolytic analgesic drugs on the motility patterns of the equine small intestine. Res Vet Sci 1983;34:334-339.
20. Gomaa N, Uhlig A, Schusser GF. Effect of Buscopan compositum on the motility of the duodenum, cecum and left ventral colon in healthy conscious horses. Berl Munch Tierarztl Wochenschr 2011;124:168-174.
21. Pimenta EL, Teixeira Neto FJ, Sá PA, et al. Comparative study between atropine and hyoscine-N-butylbromide for reversal of detomidine induced bradycardia in horses. Equine Vet J 2011;43:332-340.
22. Robinson NE, Derksen FJ, Slocombe RF. Determination of the site of airway obstruction using gases of differing density. In: Rose RJ, Snow DH, Persson SGB, eds. Equine Exercise Physiology. Cambridge: Granta Editions; 1983:71-75.
23. Broadstone RV, LeBlanc PH, Derksen FJ, Robinson NE. In vitro responses of airway smooth muscle from horses with recurrent airway obstruction. Pulm Pharmacol 1991;4:191-202.
24. Robinson NE, Olszewski MA, Boehler D, et al. Relationship between clinical signs and lung function in horses with recurrent airway obstruction (heaves) during a bronchodilator trial. Equine Vet J 2000;32:393-400.