A patient with simultaneously appearing adenocarcinoma and small-cell lung carcinoma harbouring an identical EGFR exon 19 mutation

Annals of Oncology

Volumn 23, Issue 12, 2012, Pages 3188-3189

  Van Riel, S ^a   Thunnissen, E ^b   Heideman, D ^b   Smit, E F ^b   Biesma, B ^a  

^a JEROEN BOSCH HOSPITAL   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOPLATIN; CISPLATIN; DOCETAXEL; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; GEMCITABINE; PEMETREXED;

ADULT; CANCER RECURRENCE; CANCER STAGING; CASE REPORT; CLINICAL FEATURE; DIZZINESS; EGFR GENE; EXON; FEMALE; GENE DELETION; GENE MUTATION; HUMAN; HUMAN TISSUE; LETTER; LUNG ADENOCARCINOMA; LUNG SMALL CELL CANCER; NUCLEAR MAGNETIC RESONANCE IMAGING; ONCOGENE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; STEREOTACTIC BODY RADIATION THERAPY; TRACHEOBRONCHIAL TOILET; TUMOR BIOPSY;

EID: 84869853435     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mds525     Document Type: Letter

References (5)

1. Tatematsu A, Shimizu J, Murakami Y et al. Epidermal growth factor receptor mutations in small cell lung cancer. Clin Cancer Res 2008; 14: 6092-6096.
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3. Sequist LV, Waltman BA, Dias-Santagata D et al. Gemotypic and histologiacal evolution of lung cancers acquiring resistance to EGFR inhibitors. Sci Transl Med 2011; 3: 75ra26.
4. Zakowski MF, Ladanyi M, Kris MG. EGFR mutations in small-cell lung cancers in patients who have never smoked. N Engl J Med 2006; 355: 213-215.
5. Turke AB, Zejnullahu K, Wu YL et al. Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC. Cancer Cell 2010; 17: 77-88.