Fractalkine and its receptor (CX3CR1) in patients with stable coronary artery disease and diabetes mellitus

Metabolic Syndrome and Related Disorders

Volumn 10, Issue 6, 2012, Pages 400-406

  Njerve, Ida Unhammer ^a,b   Pettersen, Alf Åge ^a,b   Opstad, Trine Baur ^a,b   Arnesen, Harald ^a,b,c   Seljeflot, Ingebjørg ^a,b,c  

^a ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANGIOTENSIN RECEPTOR ANTAGONIST; C REACTIVE PROTEIN; CHEMOKINE RECEPTOR CX3CR1; MONOCYTE CHEMOTACTIC PROTEIN 1;

ADULT; ANTICOAGULANT THERAPY; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CROSS-SECTIONAL STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; SMOKING;

AGED; CHEMOKINE CX3CL1; CORONARY ARTERY DISEASE; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; DISEASE PROGRESSION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; HUMANS; MALE; METABOLIC SYNDROME X; MIDDLE AGED; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RECEPTORS, CHEMOKINE;

EID: 84869795201     PISSN: 15404196     EISSN: 15578518     Source Type: Journal    
DOI: 10.1089/met.2012.0052     Document Type: Article

References (26)

1. Umehara H, Bloom ET, Okazaki T, et al. Fractalkine in vascular biology: From basic research to clinical disease. Arterioscler Thromb Vasc Biol 2004;24:34-40. (Pubitemid 38082409)
2. Bazan JF, Bacon KB, Hardiman G, et al. A new class of membrane-bound chemokine with a CX3C motif. Nature 1997;385:640-644.
3. Imai T, Hieshima K, Haskell C, et al. Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion. Cell 1997;91:521-530. (Pubitemid 27508241)
4. Greaves DR, Hakkinen T, Lucas AD, et al. Linked chromosome 16q13 chemokines, macrophage-derived chemokine, fractalkine, and thymus-and activation-regulated chemokine, are expressed in human atherosclerotic lesions. Arterioscler Thromb Vasc Biol 2001;21:923-929. (Pubitemid 34168647)
5. Shah R, Hinkle CC, Ferguson JF, et al. Fractalkine is a novel human adipochemokine associated with type 2 diabetes. Diabetes 2011;60:1512-1518.
6. Wong BW, Wong D, McManus BM. Characterization of fractalkine (CX3CL1) and CX3CR1 in human coronary arteries with native atherosclerosis, diabetes mellitus, and transplant vascular disease. Cardiovasc Pathol 2002;11:332-338. (Pubitemid 35380022)
7. Manduteanu I, Pirvulescu M, Gan AM, et al. Similar effects of resistin and high glucose on P-selectin and fractalkine expression and monocyte adhesion in human endothelial cells. Biochem Biophys Res Commun 2010;391: 1443-1448.
8. Dragomir E, Manduteanu I, Calin M, et al. High glucose conditions induce upregulation of fractalkine and monocyte chemotactic protein-1 in human smooth muscle cells. Thromb Haemost 2008;100:1155-1165.
9. Meng L, Park J, Cai Q, et al. Diabetic conditions promote binding of monocytes to vascular smooth muscle cells and their subsequent differentiation. Am J Physiol Heart Circ Physiol 2010;298:H736-H745.
10. Yadav A, Saini V, Arora S. MCP-1: Chemoattractant with a role beyond immunity: A review. Clin Chim Acta 2010;411: 1570-1579.
11. Braunersreuther V, Mach F, Steffens S. The specific role of chemokines in atherosclerosis. Thromb Haemost 2007;97:714-721. (Pubitemid 46804314)
12. Saederup N, Chan L, Lira SA, et al. Fractalkine deficiency markedly reduces macrophage accumulation and atherosclerotic lesion formation in CCR2-/-mice: Evidence for independent chemokine functions in atherogenesis. Circulation 2008;117:1642-1648. (Pubitemid 351482604)
13. Combadiere C, Potteaux S, Gao JL, et al. Decreased atherosclerotic lesion formation in CX3CR1/apolipoprotein E double knockout mice. Circulation 2003;107:1009-1016. (Pubitemid 36258725)
14. Lesnik P, Haskell CA, Charo IF. Decreased atherosclerosis in CX3CR1-/-mice reveals a role for fractalkine in atherogenesis. J Clin Invest 2003;111:333-340. (Pubitemid 36182209)
15. Jerath MR, Liu P, Struthers M, et al. Dual targeting of CCR2 and CX3CR1 in an arterial injury model of vascular inflammation. Thromb J 2010;8:14.
16. White GE, Greaves DR. Fractalkine: A survivor's guide: Chemokines as antiapoptotic mediators. Arterioscler Thromb Vasc Biol 2012;32:589-594.
17. Pettersen AA, Seljeflot I, Abdelnoor M, et al. Unstable angina, stroke, myocardial infarction and death in aspirin nonresponders. A prospective, randomized trial. The ASCET (ASpirin non-responsiveness and Clopidogrel Endpoint Trial) design. Scand Cardiovasc J 2004;38:353-356. (Pubitemid 40123793)
18. Grundy SM, Cleeman JI, Daniels SR, et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement: Executive Summary. Crit Pathw Cardiol 2005;4:198-203. (Pubitemid 41697502)
19. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001;25:402-408. (Pubitemid 34164012)
20. Damas JK, Boullier A, Waehre T, et al. Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, is elevated in coronary artery disease and is reduced during statin therapy. Arterioscler Thromb Vasc Biol 2005;25:2567-2572. (Pubitemid 43732280)
21. Mercurio V, Carlomagno G, Fazio V, et al. Insulin resistance: Is it time for primary prevention? World J Cardiol. 2012;4:1-7.
22. Maegdefessel L, Schlitt A, Pippig S, et al. Patients with insulin-dependent diabetes or coronary heart disease following rehabilitation express serum fractalkine levels similar to those in healthy control subjects. Vasc Health Risk Manag 2009;5:849-857.
23. Jiang DQ, Liu H, Zhang SB, et al. Aspirin inhibits tumor necrosis factor-alpha-stimulated fractalkine expression in human umbilical vein endothelial cells. Chin Med J (Engl) 2009;122:1147-1153.
24. Liu H, Jiang D, Zhang S, et al. Aspirin inhibits fractalkine expression in atherosclerotic plaques and reduces atherosclerosis in ApoE gene knockout mice. Cardiovasc Drugs Ther 2010;24:17-24.
25. Xiong Z, Leme AS, Ray P, et al. CX3CR1 + lung mononuclear phagocytes spatially confined to the interstitium produce TNF-alpha and IL-6 and promote cigarette smokeinduced emphysema. J Immunol 2011;186:3206-3214.
26. Fyhrquist F, Saijonmaa O. Renin-angiotensin system revisited. J Intern Med 2008;264:224-236.