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Volumn 23, Issue 12, 2012, Pages 3069-3074

Chemotherapy (CT) and hormonotherapy (HT) as neoadjuvant treatment in luminal breast cancer patients: Results from the GEICAM/2006-03, a multicenter, randomized, phase-II study

Author keywords

Chemotherapy; Hormonotherapy; Luminal breast cancer; Neoadjuvant

Indexed keywords

CYCLOPHOSPHAMIDE; DOCETAXEL; EPIRUBICIN; ESTROGEN RECEPTOR; EXEMESTANE; GOSERELIN; KI 67 ANTIGEN; PROGESTERONE RECEPTOR;

EID: 84869740457     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mds132     Document Type: Article
Times cited : (172)

References (43)
  • 1
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumours
    • Perou CM, Sorlie T, Eisen MB et al. Molecular portraits of human breast tumours. Nature 2000; 406: 747-752.
    • (2000) Nature , vol.406 , pp. 747-752
    • Perou, C.M.1    Sorlie, T.2    Eisen, M.B.3
  • 2
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • Sorlie T, Perou CM, Tibshirani R et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 2001; 98: 10869-10874.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10869-10874
    • Sorlie, T.1    Perou, C.M.2    Tibshirani, R.3
  • 3
    • 0037478605 scopus 로고    scopus 로고
    • Repeated observation of breast tumor subtypes in independent gene expression data sets
    • Sorlie T, Tibshirani R, Parker J et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci USA 2003; 100: 8418-8423.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8418-8423
    • Sorlie, T.1    Tibshirani, R.2    Parker, J.3
  • 4
    • 33746547467 scopus 로고    scopus 로고
    • Classification and risk stratification of invasive breast carcinomas using a real-time quantitative RT-PCR assay
    • Perreard L, Fan C, Quackenbush JF et al. Classification and risk stratification of invasive breast carcinomas using a real-time quantitative RT-PCR assay. Breast Cancer Res 2006; 8: R23.
    • (2006) Breast Cancer Res , vol.8
    • Perreard, L.1    Fan, C.2    Quackenbush, J.F.3
  • 5
    • 33646874546 scopus 로고    scopus 로고
    • The molecular portraits of breast tumors are conserved across microarray platforms
    • Hu Z, Fan C, Oh DS et al. The molecular portraits of breast tumors are conserved across microarray platforms. BMC Genomics 2006; 7: 96.
    • (2006) BMC Genomics , vol.7 , pp. 96
    • Hu, Z.1    Fan, C.2    Oh, D.S.3
  • 6
    • 33645820586 scopus 로고    scopus 로고
    • Estrogen-regulated genes predict survival in hormone receptor-positive breast cancers
    • Oh DS, Troester MA, Usary J et al. Estrogen-regulated genes predict survival in hormone receptor-positive breast cancers. J Clin Oncol 2006; 24: 1656-1664.
    • (2006) J Clin Oncol , vol.24 , pp. 1656-1664
    • Oh, D.S.1    Troester, M.A.2    Usary, J.3
  • 7
    • 0042838307 scopus 로고    scopus 로고
    • Breast cancer classification and prognosis based on gene expression profiles from a population-based study
    • Sotiriou C, Neo SY, McShane LM et al. Breast cancer classification and prognosis based on gene expression profiles from a population-based study. Proc Natl Acad Sci USA 2003; 100: 10393-10398.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10393-10398
    • Sotiriou, C.1    Neo, S.Y.2    McShane, L.M.3
  • 8
    • 77449105717 scopus 로고    scopus 로고
    • An integration of complementary strategies for gene-expression analysis to reveal novel therapeutic opportunities for breast cancer
    • Bild AH, Parker JS, Gustafson AM et al. An integration of complementary strategies for gene-expression analysis to reveal novel therapeutic opportunities for breast cancer. Breast Cancer Res 2009; 11: R55.
    • (2009) Breast Cancer Res , vol.11
    • Bild, A.H.1    Parker, J.S.2    Gustafson, A.M.3
  • 10
    • 67549125237 scopus 로고    scopus 로고
    • Are we HER-ting for innovation in neoadjuvant breast cancer design?
    • Snoj N, Bedard PL, de Azambuja E et al. Are we HER-ting for innovation in neoadjuvant breast cancer design? Breast Cancer Res 2009; 11: 201.
    • (2009) Breast Cancer Res , vol.11 , pp. 201
    • Snoj, N.1    Bedard, P.L.2    de Azambuja, E.3
  • 11
    • 56749169261 scopus 로고    scopus 로고
    • Presurgical systemic treatment of nonmetastatic breast cancer: facts and open questions
    • Berruti A, Brizzi MP, Generali D et al. Presurgical systemic treatment of nonmetastatic breast cancer: facts and open questions. Oncologist 2008; 13: 1137-1148.
    • (2008) Oncologist , vol.13 , pp. 1137-1148
    • Berruti, A.1    Brizzi, M.P.2    Generali, D.3
  • 12
    • 39149111633 scopus 로고    scopus 로고
    • Preoperative chemotherapy: Updates of National Surgical Adjuvant Breast and Bowel Project Protocols B-18 and B-27
    • Rastogi P, Anderson SJ, Bear HD et al. Preoperative chemotherapy: Updates of National Surgical Adjuvant Breast and Bowel Project Protocols B-18 and B-27. J Clin Oncol 2008; 26: 778-785.
    • (2008) J Clin Oncol , vol.26 , pp. 778-785
    • Rastogi, P.1    Anderson, S.J.2    Bear, H.D.3
  • 13
    • 0037041610 scopus 로고    scopus 로고
    • Prognostic significance of complete pathological response after induction chemotherapy in operable breast cancer
    • Chollet P, Amat S, Cure H et al. Prognostic significance of complete pathological response after induction chemotherapy in operable breast cancer. Br J Cancer 2002; 86: 1041-1046.
    • (2002) Br J Cancer , vol.86 , pp. 1041-1046
    • Chollet, P.1    Amat, S.2    Cure, H.3
  • 14
    • 0037087562 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy in breast cancer:significantly enhanced response with docetaxel
    • Smith IC, Heys SD, Hutcheon AW et al. Neoadjuvant chemotherapy in breast cancer:significantly enhanced response with docetaxel. J Clin Oncol 2002; 20: 1456-1466.
    • (2002) J Clin Oncol , vol.20 , pp. 1456-1466
    • Smith, I.C.1    Heys, S.D.2    Hutcheon, A.W.3
  • 15
    • 5144219905 scopus 로고    scopus 로고
    • Chemotherapy is more effective in patients with breast cancer not expressing steroid hormone receptors: a study of preoperative treatment
    • Colleoni M, Viale G, Zahrieh D et al. Chemotherapy is more effective in patients with breast cancer not expressing steroid hormone receptors: a study of preoperative treatment. Clin Cancer Res 2004; 10: 6622-6628.
    • (2004) Clin Cancer Res , vol.10 , pp. 6622-6628
    • Colleoni, M.1    Viale, G.2    Zahrieh, D.3
  • 16
    • 9144242764 scopus 로고    scopus 로고
    • Comparative value of tumour grade, hormonal receptors, Ki 67 HER2 and topoisomerase II alpha status as predictive markers in breast cancer patients treated with neoadjuvant anthracycline based chemotherapy
    • Petit T, Wilt M, Velten M et al. Comparative value of tumour grade, hormonal receptors, Ki 67, HER2 and topoisomerase II alpha status as predictive markers in breast cancer patients treated with neoadjuvant anthracycline based chemotherapy. Eur J Cancer 2004; 40: 205-211.
    • (2004) Eur J Cancer , vol.40 , pp. 205-211
    • Petit, T.1    Wilt, M.2    Velten, M.3
  • 17
    • 21244497296 scopus 로고    scopus 로고
    • Cytotoxic and antiproliferative activity of the single agent epirubicin plus tamoxifen as primary chemotherapy in human breast cancer: a single institution phase III trial
    • Bottini A, Berruti A, Brizzi MP et al. Cytotoxic and antiproliferative activity of the single agent epirubicin plus tamoxifen as primary chemotherapy in human breast cancer: a single institution phase III trial. Endocr Relat Cancer 2005; 12: 383-392.
    • (2005) Endocr Relat Cancer , vol.12 , pp. 383-392
    • Bottini, A.1    Berruti, A.2    Brizzi, M.P.3
  • 18
    • 32544453873 scopus 로고    scopus 로고
    • Pathological complete response and residual DCIS following neoadjuvant chemotherapy for breast carcinoma
    • Jones RL, Lakhani SR, Ring AE et al. Pathological complete response and residual DCIS following neoadjuvant chemotherapy for breast carcinoma. Br J Cancer 2006; 94: 358-362.
    • (2006) Br J Cancer , vol.94 , pp. 358-362
    • Jones, R.L.1    Lakhani, S.R.2    Ring, A.E.3
  • 19
    • 33847063053 scopus 로고    scopus 로고
    • The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypes
    • Carey LA, Dees EC, Sawyer L et al. The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypes. Clin Cancer Res 2007; 13: 2329-2334.
    • (2007) Clin Cancer Res , vol.13 , pp. 2329-2334
    • Carey, L.A.1    Dees, E.C.2    Sawyer, L.3
  • 20
    • 66349089054 scopus 로고    scopus 로고
    • Phase III trial evaluating the addition of paclitaxel to doxorubicin followed by cyclophosphamide, methotrexate, and fluorouracil, as adjuvant or primary systemic therapy: European Cooperative Trial in Operable Breast Cancer
    • Gianni L, Baselga J, Eiermann W et al. Phase III trial evaluating the addition of paclitaxel to doxorubicin followed by cyclophosphamide, methotrexate, and fluorouracil, as adjuvant or primary systemic therapy: European Cooperative Trial in Operable Breast Cancer. J Clin Oncol 2009; 20: 2474-2481.
    • (2009) J Clin Oncol , vol.20 , pp. 2474-2481
    • Gianni, L.1    Baselga, J.2    Eiermann, W.3
  • 21
    • 77956861823 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy of breast cancer: tumor markers as predictors of pathologic response, recurrence, and survival
    • Precht LM, Lowe KL, Atwood M et al. Neoadjuvant chemotherapy of breast cancer: tumor markers as predictors of pathologic response, recurrence, and survival. Breast J 2010; 4: 362-368.
    • (2010) Breast J , vol.4 , pp. 362-368
    • Precht, L.M.1    Lowe, K.L.2    Atwood, M.3
  • 22
    • 77949357106 scopus 로고    scopus 로고
    • Immunohistochemical surrogate markers of breast cancer molecular classes predicts response to neoadjuvant chemotherapy: a single institutional experience with 359 cases
    • Bhargava R, Beriwal S, Dabbs DJ et al. Immunohistochemical surrogate markers of breast cancer molecular classes predicts response to neoadjuvant chemotherapy: a single institutional experience with 359 cases. Cancer 2010; 15(116): 1431-1439.
    • (2010) Cancer , vol.15 , Issue.116 , pp. 1431-1439
    • Bhargava, R.1    Beriwal, S.2    Dabbs, D.J.3
  • 23
    • 72449204608 scopus 로고    scopus 로고
    • Concordance of clinical and molecular breast cancer subtyping in the context of preoperative chemotherapy response
    • De Ronde JJ, Hannemann J, Halfwerk H et al. Concordance of clinical and molecular breast cancer subtyping in the context of preoperative chemotherapy response. Breast Cancer Res Treat. 2010; 119: 119-126.
    • (2010) Breast Cancer Res Treat , vol.119 , pp. 119-126
    • De Ronde, J.J.1    Hannemann, J.2    Halfwerk, H.3
  • 24
    • 84865191389 scopus 로고    scopus 로고
    • Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results form the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 657)
    • Esserman LJ, Berry DA, Cheang MC et al. Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results form the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 657). Breast Cancer Res Treat 2012; 132: 1049-1062.
    • (2012) Breast Cancer Res Treat , vol.132 , pp. 1049-1062
    • Esserman, L.J.1    Berry, D.A.2    Cheang, M.C.3
  • 25
    • 23844549918 scopus 로고    scopus 로고
    • Breast cancer molecular subtypes respond differently to preoperative chemotherapy
    • Rouzier R, Perou C, Symmans WF et al. Breast cancer molecular subtypes respond differently to preoperative chemotherapy. Clin Cancer Res 2005; 11: 5678-5685.
    • (2005) Clin Cancer Res , vol.11 , pp. 5678-5685
    • Rouzier, R.1    Perou, C.2    Symmans, W.F.3
  • 26
    • 77954160479 scopus 로고    scopus 로고
    • Breast cancer molecular subtypes predict response to anthracycline/taxane based chemotherapy
    • (abstract 2019)
    • Parker J, Prat A, Cheang M et al. Breast cancer molecular subtypes predict response to anthracycline/taxane based chemotherapy. San Antonio Breast Cancer Symposium 2009: (abstract 2019): 598s.
    • (2009) San Antonio Breast Cancer Symposium
    • Parker, J.1    Prat, A.2    Cheang, M.3
  • 27
    • 47949130222 scopus 로고    scopus 로고
    • Neoadjuvant endocrine therapy for breast cancer: past, present and future
    • Barnadas A, Gil M, Sanchez-Rovira P et al. Neoadjuvant endocrine therapy for breast cancer: past, present and future. Anticancer Drugs 2008; 19: 339-347.
    • (2008) Anticancer Drugs , vol.19 , pp. 339-347
    • Barnadas, A.1    Gil, M.2    Sanchez-Rovira, P.3
  • 28
    • 41649102048 scopus 로고    scopus 로고
    • Response to neoadjuvant therapy and long term survival in patients with triple negative breast cancer
    • Liedtke C, Mazouni C, Hess KR et al. Response to neoadjuvant therapy and long term survival in patients with triple negative breast cancer. J Clin Oncol 2008; 26: 1275-1281.
    • (2008) J Clin Oncol , vol.26 , pp. 1275-1281
    • Liedtke, C.1    Mazouni, C.2    Hess, K.R.3
  • 29
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors
    • Therasse P, Arbuck SG, Eisenhauer EA et al. New guidelines to evaluate the response to treatment in solid tumors. J Natl Cancer Inst 2000; 92: 205-216.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3
  • 30
    • 0142211270 scopus 로고    scopus 로고
    • A new histological grading system to assess response of breast cancers to primary chemotherapy: prognostic significance and survival
    • Ogston KN, Miller ID, Payne S et al. A new histological grading system to assess response of breast cancers to primary chemotherapy: prognostic significance and survival. Breast 2003;12(5): 320-327.
    • (2003) Breast , vol.12 , Issue.5 , pp. 320-327
    • Ogston, K.N.1    Miller, I.D.2    Payne, S.3
  • 31
    • 84871062392 scopus 로고    scopus 로고
    • National Cancer Institute Common Terminology Criteria for adverse events (NCI-CTCAE) version 3.0. Available at
    • National Cancer Institute Common Terminology Criteria for adverse events (NCI-CTCAE) version 3.0. Available at http://ctep.info.nih.gov/reporting/index.html.
  • 32
    • 77956474928 scopus 로고    scopus 로고
    • Neoadjuvant endocrine therapy in primary breast cancer: indications and use as research tool
    • Chia YH, Ellis MJ, Ma CX. Neoadjuvant endocrine therapy in primary breast cancer: indications and use as research tool. Br J Cancer 2010; 103: 759-764.
    • (2010) Br J Cancer , vol.103 , pp. 759-764
    • Chia, Y.H.1    Ellis, M.J.2    Ma, C.X.3
  • 33
    • 19344364880 scopus 로고    scopus 로고
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15 year survival: an overview of the randomised trials
    • Early Breast cancer Trials Collaborative Group
    • Early Breast cancer Trials Collaborative Group. Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15 year survival: an overview of the randomised trials. Lancet 2005; 365: 1687-1717.
    • (2005) Lancet , vol.365 , pp. 1687-1717
  • 34
    • 33645729203 scopus 로고    scopus 로고
    • Estrogen receptor status and outcomes of modern chemotherapy in women with node positive breast cancer
    • Berry D, Cirrincione C, Henderson IC et al. Estrogen receptor status and outcomes of modern chemotherapy in women with node positive breast cancer. JAMA 2006; 295: 1658-1667.
    • (2006) JAMA , vol.295 , pp. 1658-1667
    • Berry, D.1    Cirrincione, C.2    Henderson, I.C.3
  • 35
    • 35248895346 scopus 로고    scopus 로고
    • HER2 and response to paclitaxel in node positive breast cancer
    • Hayes DF, Thor AD, Dressler LG et al. HER2 and response to paclitaxel in node positive breast cancer. N Engl J Med 2007; 357: 1496-1506.
    • (2007) N Engl J Med , vol.357 , pp. 1496-1506
    • Hayes, D.F.1    Thor, A.D.2    Dressler, L.G.3
  • 36
    • 65549146500 scopus 로고    scopus 로고
    • Sequential docetaxel as adjuvant chemotherapy for early breast cancer (TACT): an open label, phase III, randomised controlled trial
    • Ellis P, Barrett-Lee P, Johnson L et al. Sequential docetaxel as adjuvant chemotherapy for early breast cancer (TACT): an open label, phase III, randomised controlled trial. Lancet 2009; 373: 1681-1692.
    • (2009) Lancet , vol.373 , pp. 1681-1692
    • Ellis, P.1    Barrett-Lee, P.2    Johnson, L.3
  • 37
    • 34547191815 scopus 로고    scopus 로고
    • Phase 2 randomized trial of primary endocrine therapy versus chemotherapy in postmenopausal patients with estrogen receptor-positive breast cancer
    • Semiglazov VF, Semiglazov VV, Dashyan GA et al. Phase 2 randomized trial of primary endocrine therapy versus chemotherapy in postmenopausal patients with estrogen receptor-positive breast cancer. Cancer 2007; 110: 244-254.
    • (2007) Cancer , vol.110 , pp. 244-254
    • Semiglazov, V.F.1    Semiglazov, V.V.2    Dashyan, G.A.3
  • 38
    • 66849140730 scopus 로고    scopus 로고
    • Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer
    • Cheang MC, Chia SK, Voduc D et al. Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer. J Natl Cancer Inst 2009; 101: 736-750.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 736-750
    • Cheang, M.C.1    Chia, S.K.2    Voduc, D.3
  • 39
    • 78049453780 scopus 로고    scopus 로고
    • A comparison of PAM50 intrinsic subtyping with inmunohistochemistry and clinical prognostic factors in tamoxifen treated estrogen receptor positive breast cancer
    • Nielsen T, Parker JS, Leung S et al. A comparison of PAM50 intrinsic subtyping with inmunohistochemistry and clinical prognostic factors in tamoxifen treated estrogen receptor positive breast cancer. Clin Cancer Res 2010; 16: 5222-5232.
    • (2010) Clin Cancer Res , vol.16 , pp. 5222-5232
    • Nielsen, T.1    Parker, J.S.2    Leung, S.3
  • 40
    • 51349088017 scopus 로고    scopus 로고
    • Biological processes associated with breast cancer clinical outcome depend on the molecular subtypes
    • Desmedt C, Haibe-Kains B, Wirapati P et al. Biological processes associated with breast cancer clinical outcome depend on the molecular subtypes. Clin Cancer Res 2008; 14: 5158-5165.
    • (2008) Clin Cancer Res , vol.14 , pp. 5158-5165
    • Desmedt, C.1    Haibe-Kains, B.2    Wirapati, P.3
  • 41
    • 58149330982 scopus 로고    scopus 로고
    • Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures
    • Wirapati P, Sotiriou C, Kunkel S et al. Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures. Breast Cancer Res 2008; 10: R65.
    • (2008) Breast Cancer Res , vol.10
    • Wirapati, P.1    Sotiriou, C.2    Kunkel, S.3
  • 42
    • 77954934986 scopus 로고    scopus 로고
    • Phase II parrallel group study showing comparable efficacy between metastatic premenopausal breast cancer patients treated with letrozol plus goserelin and postmenopausal patients treated with letrozole alone as first line hormone therapy
    • Park IH, Ro J, Lee KS et al. Phase II parrallel group study showing comparable efficacy between metastatic premenopausal breast cancer patients treated with letrozol plus goserelin and postmenopausal patients treated with letrozole alone as first line hormone therapy. J Clin Oncol 2010; 28: 2705-2711.
    • (2010) J Clin Oncol , vol.28 , pp. 2705-2711
    • Park, I.H.1    Ro, J.2    Lee, K.S.3
  • 43
    • 77957592529 scopus 로고    scopus 로고
    • Phase II trial of anastrozole plus goserelin in the treatment of hormone receptor-positive, metastatic carcinoma of the breast in premenopausal women
    • Carlson RW, Theriault R, Schurman CM et al. Phase II trial of anastrozole plus goserelin in the treatment of hormone receptor-positive, metastatic carcinoma of the breast in premenopausal women. J Clin Oncol 2010; 28: 3917-3921.
    • (2010) J Clin Oncol , vol.28 , pp. 3917-3921
    • Carlson, R.W.1    Theriault, R.2    Schurman, C.M.3


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