3D simulation of the aqueous flow in the human eye

Medical Engineering and Physics

Volumn 34, Issue 10, 2012, Pages 1462-1470

  Villamarin, Adan ^a   Roy, Sylvain ^a,b   Hasballa, Reda ^a   Vardoulis, Orestis ^a   Reymond, Philippe ^a   Stergiopulos, Nikolaos ^a  

^a EPFL   (Switzerland)

^b Glaucoma Center   (Switzerland)

Author keywords

Anterior chamber; Aqueous humor; Glaucoma; Glaucoma surgery; Trabecular meshwork

Indexed keywords

ANTERIOR CHAMBER; AQUEOUS HUMOR; GLAUCOMA; GLAUCOMA SURGERY; TRABECULAR MESHWORKS;

BODY FLUIDS; COMPUTATIONAL FLUID DYNAMICS; OPHTHALMOLOGY; SURGERY; SURGICAL EQUIPMENT; THREE DIMENSIONAL COMPUTER GRAPHICS;

THREE DIMENSIONAL;

AQUEOUS HUMOR FLOW; ARTICLE; COMPUTATIONAL FLUID DYNAMICS; FILTERING OPERATION; FLOW RATE; GLAUCOMA; GLAUCOMA DRAINAGE IMPLANT; GLAUCOMA SURGERY; HUMAN; HUMAN TISSUE; IMAGE PROCESSING; IMAGE RECONSTRUCTION; INTRAOCULAR PRESSURE; MICROPHOTOGRAPHY; PRESSURE; PRIORITY JOURNAL; SIMULATION; SURGICAL TECHNIQUE; THREE DIMENSIONAL IMAGING;

AQUEOUS HUMOR; GLAUCOMA; HUMANS; HYDRODYNAMICS; MODELS, BIOLOGICAL; PERMEABILITY; STRESS, MECHANICAL;

EID: 84869503500     PISSN: 13504533     EISSN: 18734030     Source Type: Journal    
DOI: 10.1016/j.medengphy.2012.02.007     Document Type: Article

References (34)

1. Congdon N., O'Colmain B., Klaver C.C., Klein R., Munoz B., Friedman D.S., et al. Causes and prevalence of visual impairment among adults in the United States. Arch Ophthalmol 2004, 122:477-485.
2. Ethier C.R., Johnson M., Ruberti J. Ocular biomechanics and biotransport. Annu Rev Biomed Eng 2004, 6:249-273.
3. Kwon Y.H., Fingert J.H., Kuehn M.H., Alward W.L. Primary open-angle glaucoma. N Engl J Med 2009, 360:1113-1124.
4. Chen P.P., Yamamoto T., Sawada A., Parrish R.K., Kitazawa Y. Use of antifibrosis agents and glaucoma drainage devices in the American and Japanese Glaucoma Societies. J Glaucoma 1997, 6:192-196.
5. Joshi A.B., Parrish R.K., Feuer W.F. 2002 survey of the American Glaucoma Society: practice preferences for glaucoma surgery and antifibrotic use. J Glaucoma 2005, 14:172-174.
6. Schnyder C. Glaucome 2005, Elsevier, Paris.
7. Llobet A., Gasull X., Gual A. Understanding trabecular meshwork physiology: a key to the control of intraocular pressure. News Physiol Sci 2003, 18:205-209.
8. Bill A. Blood circulation and fluid dynamics in the eye. Physiol Rev 1975, 55:383-417.
9. Bill A., Phillips C.I. Uveoscleral drainage of aqueous humour in human eyes. Exp Eye Res 1971, 12:275-281.
10. Irshad F.A., Mayfield M.S., Zurakowski D., Ayyala R.S. Variation in Schlemm's canal diameter and location by ultrasound biomicroscopy. Ophthalmology 2010, 117:916-920.
11. Flammer J. Glaucoma: a guide for patients; an introduction for care-providers; a reference for quick information 2001, Huber, Bern.
12. Canning C.R., Greaney M.J., Dewynne J.N., Fitt A.D. Fluid flow in the anterior chamber of a human eye. IMA J Math Appl Med Biol 2002, 19:31-60.
13. Ethier C.R., Kamm R.D., Palaszewski B.A., Johnson M.C., Richardson T.M. Calculations of flow resistance in the juxtacanalicular meshwork. Invest Ophthalmol Vis Sci 1986, 27:1741-1750.
14. Heys J.J., Barocas V.H. A Boussinesq model of natural convection in the human eye and the formation of Krukenberg's spindle. Ann Biomed Eng 2002, 30:392-401.
15. Johnson M.C., Kamm R.D. The role of Schlemm's canal in aqueous outflow from the human eye. Invest Ophthalmol Vis Sci 1983, 24:320-325.
16. Scott J.A. The computation of temperature rises in the human eye induced by infrared radiation. Phys Med Biol 1988, 33:243-257.
17. Scott J.A. A finite element model of heat transport in the human eye. Phys Med Biol 1988, 33:227-241.
18. Kumar S., Acharya S., Beuerman R., Palkama A. Numerical solution of ocular fluid dynamics in a rabbit eye: parametric effects. Ann Biomed Eng 2006, 34:530-544.
19. Cairns J.E. Trabeculectomy preliminary report of a new method. Am J Ophthalmol 1968, 66:673-679.
20. Avtar R., Srivastava R. Modelling aqueous humor outflow through trabecular meshwork. Appl Math Comput 2007, 189:734-745.
21. Kocak I., Orgul S., Flammer J. Variability in the measurement of corneal temperature using a noncontact infrared thermometer. Ophthalmologica 1999, 213:345-349.
22. Karampatzakis A., Samaras T. Numerical model of heat transfer in the human eye with consideration of fluid dynamics of the aqueous humour. Phys Med Biol 2010, 55:5653-5665.
23. Ooi E., Ng E. Simulation of aqueous humor hydrodynamics in human eye heat transfer. Comput Biol Med 2008, 38:252-262.
24. Johnson M. What controls aqueous humour outflow resistance. Exp Eye Res 2006, 82:545-557.
25. Murphy C.G., Johnson M., Alvarado J.A. Juxtacanalicular tissue in pigmentary and primary open angle glaucoma. The hydrodynamic role of pigment and other constituents. Arch Ophthalmol 1992, 110:1779-1785.
26. Reneman R.S., Arts T., Hoeks A.P. Wall shear stress-an important determinant of endothelial cell function and structure-in the arterial system in vivo. Discrepancies with theory. J Vasc Res 2006, 43:251-269.
27. Ethier C.R., Read A.T., Chan D. Biomechanics of Schlemm's Canal Endothelial Cells: influence on F-actin architecture. Biophys J 2004, 87:2828-2837.
28. Lehto I., Ruusuvaara P., Setala K. Corneal endothelium in pigmentary glaucoma and pigment dispersion syndrome. Acta Ophthalmol 1990, 68:703-709.
29. Gerlach J.C., Hentschel F., Spatkowski G., Zeilinger K., Smith M.D., Neuhaus P. Cell detachment during sinusoidal reperfusion after liver preservation: an in vitro model. Transplantation 1997, 64:907-912.
30. Maris P.J., Ishida K., Netland P.A. Comparison of trabeculectomy with Ex-PRESS miniature glaucoma device implanted under scleral flap. J Glaucoma 2007, 16:14-19.
31. Broquet J., Roy S., Mermoud A. Visualization of the aqueous outflow pathway in the glaucoma surgery by finite element model of the eye. Comput Methods Biomech Biomed Eng 2005, 8:43-44.
32. Toris C.B., Yablonski M.E., Camras C.B., Gleason M.L. Uveoscleral outflow decreases with age in ocular normotensive humans. Invest Ophthalmol Vis Sci 1996, 37:1909.
33. Townsend D.J., Brubaker R.F. Immediate effect of epinephrine on aqueous formation in the normal human eye as measured by fluorophotometry. Invest Ophthalmol Vis Sci 1980, 19:256-266.
34. Bill A. Further studies on the influence of the intraocular pressure on aqueous humour dynamics in cynomolgus monkeys. Invest Ophthalmol Vis Sci 1967, 6:364-372.