SOD1, but not SOD3, deficiency accelerates diabetic renal injury in C57BL/6-Ins2Akita diabetic mice

Metabolism: Clinical and Experimental

Volumn 61, Issue 12, 2012, Pages 1714-1724

  Fujita, Hiroki ^a,b   Fujishima, Hiromi ^a   Takahashi, Keiko ^b   Sato, Takehiro ^a   Shimizu, Tatsunori ^a   Morii, Tsukasa ^a   Shimizu, Takahiko ^c   Shirasawa, Takuji ^c,d   Qi, Zhonghua ^b   Breyer, Matthew D ^b   Harris, Raymond C ^b   Yamada, Yuichiro ^a   Takahashi, Takamune ^b  

^a AKITA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^d JUNTENDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Akita mouse; Diabetic nephopathy; Knockout mouse; Oxidative stress; Superoxide dismutase

Indexed keywords

ALBUMIN; CONNECTIVE TISSUE GROWTH FACTOR; COPPER ZINC SUPEROXIDE DISMUTASE; EXTRACELLULAR SUPEROXIDE DISMUTASE; MESSENGER RNA; NITRIC OXIDE; PROSTAGLANDIN E2; TRANSFORMING GROWTH FACTOR BETA1;

ALBUMINURIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DISEASE SEVERITY; DOWN REGULATION; ENDOTHELIAL DYSFUNCTION; ENZYME DEFICIENCY; GLOMERULUS; GLOMERULUS FILTRATION RATE; KIDNEY HYPERTROPHY; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ALBUMINURIA; ANIMALS; BLOTTING, WESTERN; CONNECTIVE TISSUE GROWTH FACTOR; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; DINOPROSTONE; GLOMERULAR FILTRATION RATE; GLOMERULAR MESANGIUM; KIDNEY GLOMERULUS; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; NITRIC OXIDE; OXIDATIVE STRESS; REAL-TIME POLYMERASE CHAIN REACTION; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84869502438     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2012.05.005     Document Type: Article

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